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| 1 | Intelligent metasurfaces:control,communication and computing显示文摘Controlling electromagnetic waves and information simultaneously by information metasurfaces is of central importance in modern society.Intelligent metasurfaces are smart platforms to manipulate the wave-information-matter interactions without manual intervention by synergizing engineered ultrathin structures with active devices and algorithms,which evolve from the passive composite materials for tailoring wave-matter interactions that cannot be achieved in nature.Here,we review the recent progress of intelligent metasurfaces in wave-information-matter controls by providing the historical background and underlying physical mechanisms.Then we explore the application of intelligent metasurfaces in developing novel wireless communication architectures,with particular emphasis on metasurface-modulated backscatter wireless communications.We also explore the wave-based computing by using the intelligent metasurfaces,focusing on the emerging research direction in intelligent sensing.Finally,we comment on the challenges and highlight the potential routes for the further developments of the intelligent metasurfaces for controls,communications and computing. | Lianlin Li Hanting Zhao Che Liu Long Li Tie Jun Cui | 2022 | eLight2022，2，1： | 7 |
| 2 | Dietary energy intake affects fetal survival and development during early and middle pregnancy in Large White and Meishan gilts显示文摘This experiment was designed to determine the effects of variations in dietary energy intake on reproductive performance and gene expression of luteal and endometrium tissues in Large White(LW)and Meishan(MS) gilts during early and middle pregnancy. After insemination, 32 LW gilts were assigned to high and low(HE_Land LE_L, 14.23 and 12.56 MJ DE/kg, respectively) diet treatment groups,while 32 MS gilts were allocated to HE_M and LE_M(12.56 and 10.88 MJ DE/kg) groups. Gilts were slaughtered on days 35, 55 and 90 of gestation. The fetal survival and luteal progesterone(P_4) concentration in the HE_Lgroup were higher on day 35 but lower on day 90 of gestation compared with the LE_L group(P < 0.05) for LW gilts. However, fetal survival and luteal P_4 concentration on day 35 of gestation were greater(P < 0.05) in the LE_M group than in the HE_M group for MS gilts, but no significant difference in mid-gestation was showed. The fetal weights of both breeds were higher for the high energy diets compared with the respective control group on day 90 of gestation(P < 0.05). In addition,the m RNA levels of P_4 synthesis-related proteins had correlated with luteal P_4 concentration in both breeds. Further, endometrial levels of uteroferrin(ACP5), retinol-binding protein 4(RBP_4) and secreted phosphoprotein 1(SPP1) m RNA were upregulated in the HE_Lgroup on day 35 of gestation but ACP5 and SPP1 were downregulated on day 55 of gestation compared with the LE_Lgroup(P < 0.05) for LW gilts. In MS gilts, diet only affected the expression of SPP1(P < 0.05). Our results revealed the differential sensitivity of LW and MS breeds to variations in dietary energy intake. For LW gilts, the HE_Lgroup improved fetal survival on day 35 but a sustained high energy diet decreased fetal survival on day 90 of gestation. The differences in dietary energy intake did not influence fetal survival on day 90 of gestation but the higher energy diet did increase fetal weight in the MS breed compared with the lower energy intake diet. These results may be due to differential luteal secretion activity and endometrium gene expression in these two breeds. | Long Che Zhenguo Yang Mengmeng Xu Ziyun Zhang Peilin Liu Shengyu Xu Lianqiang Che Yan Lin Zhengfeng Fang Bin Feng Jian Li De Wu | 2015 | Animal Nutrition2015，，3： | 4 |
| 3 | Effects of dietary valine supplementation during late gestation on the reproductive performance and mammary gland development of gilts显示文摘Background:Mammary gland development during late gestation in gilts is a major factor that alters the composition of colostrum and growth performance of piglets.Plasma valine is taken up and metabolized extensively by the mammary gland;however,the effects of valine on mammary gland development during late gestation are still unclear.Thirty primiparous gilts were divided into three treatment groups(n=10)and received one of the three diets starting on day 75 of gestation until the day of farrowing.The total dietary valine to lysine ratio of the three diets was 0.63(LV),0.73(MV),and 0.93(HV),respectively.Results:Dietary valine supplementation during late gestation did not affect(P>0.05)the litter size and weight at farrowing;however,the piglet weight and average daily gain at weaning were linearly increased(P<0.05)as the dietary valine increased.The highest piglet weight at weaning was observed when the gilts were provided the HV diet.Dietary valine supplementation linearly elevated(P<0.05)protein,fat and solids-not-fat and some free amino acids content in colostrum.The concentration of prolactin in plasma of gilts was linearly increased in response to valine supplementation at days 1 and 10 of lactation(P<0.05).Furthermore,with increasing dietary valine allowance,a linear increase(P<0.05)was observed in the area of the lumen of alveolus and the content of DNA,RNA,and total protein in the mammary tissues at day 1 of lactation.Moreover,the protein expression of cyclin D1,p-mTOR,p-S6,and p-4EBP1 was also linearly increased(P<0.05)in the mammary tissue at day 1 of lactation.However,no difference(P>0.05)was observed in the indices related to mammary development and the mTOR signaling pathway at day 21 of lactation.Conclusion:The results revealed that increasing the total dietary valine to lysine ratio to 0.93 during late gestation significantly enhances the piglet weight and average daily gain at weaning probably due to improved development of mammary gland. | Long Che Mengmeng Xu Kaiguo Gao Li Wang Xuefen Yang Xiaolu Wen Hao Xiao Zongyong Jiang | 2020 | Journal of Animal Science and Biotechnology2020，11，2： | 4 |
| 4 | The Role of HBx Gene Mutations in PLA2R Positive Hepatitis-B-associated Membranous Nephropathy显示文摘China is a higher-intermediate hepatitis B virus(HBV)endemicity country,and HBV is among the most important infectious diseases[1,2].Hepatitis-Bassociated glomerulonephritis(HBV-GN)is also one of the main forms of secondary kidney diseases seen in China[3].The main pathological type is hepatitis-Bassociated membranous nephropathy(HBV-MN).In the recent years,it has been found that human renal podocyte membrane M-type phospholipase 2 receptor(PLA2R)is the main autoantigen in idiopathic membranous nephropathy(IMN)[4].At present,it is found that PLA2 R and its antibodies are. | DONG Hui XU Yan XU Ting SUN Jing Yi BU Quan Dong WANG Yan Fei CHE Lin ZHAO Long JIANG Wei | 2020 | Biomedical and Environmental Sciences2020，33，4： | 3 |
| 5 | Development of DWDM Filter Manufacture显示文摘DWDM technology is developing rapidly. Thin film narrow bandpass filter plays an important role in this field. This article presents some achievements in developing the DWDM narrow bandpass filters and also describes the results achieved by us. | MIAO Tong qun,JIN Nan shan, ZHOU Fang che, QIAN Long sheng (Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences, Changchun 130022, China) | 2001 | 光学精密工程2001，9，5： | 3 |
| 6 | Highly Efficient Organic Ultraviolet Photodetectors Based on Re(I) Complexes显示文摘High response organic ultraviolet photodetectors(UV-PDs) were demonstrated with 4,4',4''tris[3-methyl-pheny(phenyl)amino]triphenylamine(m-MTDATA) and two Re(I) complexes,(bathocuproine)Re(CO)3 Cl(Re-BCP) and(bathophenanthroline)Re(CO)3 Cl(Re-Bphen) to act as the electron donor and acceptor,respectively.UV-PDs have the configuration of indium tin oxide(ITO)/m-MTDATA(25nm)/m-MTDATA:Re-complex(25―35nm)/Re-complex(20nm)/LiF(1 nm)/Al(200 nm) with different blend layer thicknesses of 25,30 and 35 nm.The optimized PD based on Re-Bphen offers a corrected-dark photocurrent up to 760 μA/cm2 at 10 V,corresponding to a response of 310 mA/W which is among the best values reported for organic UV-PDs.Excellent electron transport ability makes for such high photo-to-electron conversion. | LIU Chun-bo WANG Long LIU Min LI Chuan-bi LI Chun-mei CHE Guang-bo SU Bin | 2012 | Chemical Research in Chinese Universities2012，28，3： | 3 |
| 7 | Genome-wide analysis reveals selection for Chinese Rongchang pigs显示文摘Livestock have undergone domestication and consequently strong selective pressure on genes or genomic regions that control desirable traits. To identify selection signatures in the genome of Chinese Rongchang pigs, we generated a total of about 170 Gb of DNA sequence data with about 6.4-fold coverage for each of six female individuals. By combining these data with the publically available genome data of 10 Asian wild boars,we identified 449 protein-coding genes with selection signatures in Rongchang pigs, which are mainly involved in growth and hormone binding, nervous system development, and drug metabolism. The accelerated evolution of these genes may contribute to the dramatic phenotypic differences between Rongchang pigs and Chinese wild boars. This study illustrated how domestication and subsequent artificial selection have shaped patterns of genetic variation in Rongchang pigs and provides valuable genetic resources that can enhance the use of pigs in agricultural production and biomedical studies. | Lei CHEN Shilin TIAN Long JIN Zongyi GUO Dan ZHU Lan JING Tiandong CHE Qianzi TANG Siqing CHEN Liang ZHANG Tinghuan ZHANG Zuohua LIU Jinyong WANG Mingzhou LI | 2017 | Frontiers of Agricultural Science and Engineering2017，4，3： | 2 |
| 8 | Compact CubeSat Gamma-ray detector for GRID mission显示文摘Gamma-Ray Integrated Detectors(GRID)mis-sion is a student project designed to use multiple gamma-ray detectors carried by nanosatellites(CubeSats),forming a full-time all-sky gamma-ray detection network that monitors the transient gamma-ray sky in the multi-mes-senger astronomy era.A compact CubeSat gamma-ray detector,including its hardware and firmware,was designed and implemented for the mission.The detector employs four Gd 2 Al 2 Ga 3 O 12:Ce(GAGG:Ce)scintillators coupled with four silicon photomultiplier(SiPM)arrays to achieve a high gamma-ray detection efficiency between 10 keV and 2 MeV with low power and small dimensions.The first detector designed by the undergraduate student team onboard a commercial CubeSat was launched into a Sun-synchronous orbit on October 29,2018.The detector was in a normal observation state and accumulated data for approximately one month after on-orbit functional and performance tests,which were conducted in 2019. | Jia-Xing Wen Xu-Tao Zheng Jian-Dong Yu Yue-Peng Che Dong-Xin Yang Huai-Zhong Gao Yi-Fei Jin Xiang-Yun Long Yi-Hui Liu Da-Cheng Xu Yu-Chong Zhang Ming Zeng Yang Tian Hua Feng Zhi Zeng Ji-Rong Cang Qiong Wu Zong-Qing Zhao Bin-Bin Zhang Peng An GRID collaboration | 2021 | Nuclear Science and Techniques2021，32，9： | 2 |
| 9 | Weather and Stroke in a Subtropical Area 显示文摘 | Zen-- Yong Chen MD Shu -- Feng Chang MD MPH Che -- Long Su MD | 1995 | Ilan Taiwan Stroke1995，26，4： | 1 |
| 10 | Overexpression of Nampt in gastric cancer and chemopotentiating effectsof the Nampt inhibitor FK866 in combination with fluorouracil显示文摘 | Tie-Qiang Bi Xiang-Ming Che Xin-Hua Liao Dan-Jie Zhang Hou-Long Long Hai-Jun Li Wei Zhao | 2011 | Oncology Reports2011，，5： | 1 |
| 11 | Paclitaxel/gelatin coated magnetic mesoporous silica nanoparticles:Preparation and antitumor efficacy in vivo显示文摘 | CHE Er-xi GAO Yi-kun WAN Long | 2015 | Micropor Mesopor Mat2015，204，： | 1 |
| 12 | Intra‐operative management of low portal vein flow in pediatric living donor liver transplantation显示文摘 | Ting‐Lung Lin Li‐Wei Chiang Chao‐Long Chen Shih‐Hor Wang Chih‐Che Lin Yueh‐Wei Liu Chee‐Chien Yong Tsan‐Shiun Lin Wei‐Feng Li Bruno Jawan Yu‐Fan Cheng Tai‐Yi Chen Allan M. Concejero Chih‐Chi Wang | 2012 | Transplant International2012，，5： | 1 |
| 13 | Distance-controllable and direction-steerable opto-conveyor for targeting delivery显示文摘Opto-conveyors have attracted widespread interest in various fields because of their non-invasive and non-contact delivery of micro/nanoparticles.However,the flexible control of the delivery distance and the dynamic steering of the delivery direction,although very desirable in all-optical manipulation,have not yet been achieved by optoconveyors.Here,using a simple and cost-effective scheme of an elliptically focused laser beam obliquely irradiated on a substrate,a direction-steerable and distance-controllable opto-conveyor for the targeting delivery of microparticles is implemented.Theoretically,in the proposed scheme of the opto-conveyor,the transverse and longitudinal resultant forces of the optical gradient force and the optical scattering force result in the transverse confinement and the longitudinal transportation of microparticles,respectively.In this study,it is experimentally shown that the proposed opto-conveyor is capable of realizing the targeting delivery for microparticles.Additionally,the delivery distance of microparticles can be flexibly and precisely controlled by simply adjusting the irradiation time.By simply rotating the cylindrical lens,the proposed opto-conveyor is capable of steering the delivery direction flexibly within a large range of azimuthal angles,from-75°to 75°.This study also successfully demonstrated the real-time dynamic steering of the delivery direction from-45°to 45°with the dynamical rotation of the cylindrical lens.Owing to its simplicity,flexibility,and controllability,the proposed method is capable of creating new opportunities in bioassays as well as in drug delivery. | Zhen Che Wenguo Zhu Yaoming Huang Yu Zhang Linqing Zhuo Pengpeng Fan Zhibin Li Huadan Zheng Wenjin Long Wentao Qiu Yunhan Luo Jun Zhang Jinghua Ge Jianhui Yu Zhe Chen | 2020 | Photonics Research2020，8，7： | 1 |
| 14 | KNEMAG:Key Node Estimation Mechanism Based on Attack Graph for IoT Security显示文摘With the rapid development and widespread application of the IoT,the at-tacks against IoT vulnerabilities have become more complex and diverse.Most of the previous research focused on node vulnerability and its risk analysis.There is little information available about the importance of the location of the node in the system.Therefore,an estimation mechanism is proposed to assess the key node of the IoT system.The estimation of the key node includes two parts:one is the utilization relationship between nodes,and the other is the impact on the system after the node is conquered.We use the node importance value and the node risk value to quantify these two parts.First,the node importance value is calculated by considering the attack path that pass through the node and the probability that the attacker will abandon the attack.Second,in addition to node vulnerabilities and the consequences of being attacked,two quantitative indicators are proposed to comprehensively assess the impact of nodes on the system security,and the node risk value is calculated based on the grey correlation analysis method.Third,the key node in the IoT system could be obtained by integrating the node importance value and risk value.Finally,the simulation experiment result shows that the presented method could find the key node of the system quickly and accurately. | Bichen Che Long Liu Huali Zhang | 2020 | Journal on Internet of Things2020，2，4： | 1 |
| 15 | Outcomes of long storage times for cryopreserved vascular grafts in outflow reconstruction in living donor liver transplantation显示文摘 | Chih‐Chi Wang Salvador Lopez‐Valdes Ting‐Lung Lin Anthony Yap Chee‐Chien Yong Wei‐Feng Li Shih‐Ho Wang Chih‐Che Lin Yueh‐Wei Liu Tsan‐Shiun Lin Allan M. Concejero Hock‐Liew Eng Douglas Henry Yu‐Fan Cheng Bruno Jawan Chao‐Long Chen | 2014 | Liver Transpl2014，，2： | 1 |
| 16 | Rapid Ultrasonic-Assisted Soldering of AZ31B Mg Alloy/6061 Al Alloy with Low-Melting-Point Sn–xZn Solders Without Flux in Air显示文摘A novel ultrasonic-assisted low-temperature soldering was developed to join AZ31B Mg alloy and 6061 Al alloy with a series of Sn–x Zn solders. The average maximum shear strength of the joints reaches up to 87.5 MPa at soldering temperature of 300 °C under ultrasonic assistance for only 5 s using Sn–20 Zn solder. The fracture path propagates completely in the soldering seam. The results indicate that the microjet generated by ultrasonic pressure in liquid solder could strike and splinter the Mg_2Sn intermetallic compounds into small pieces, which contributes to the enhancement of the joint strength. In addition, the primary Al(Zn) solid solution phase formed during cooling stage could also strengthen the joint due to the prevention of microcracks propagation. | Zhi-Wei Lai Zhe-Yuan Huang Chuan Pan Hui-Qiao Du Xiao-Guang Che Lei Liu Wei-Ming Long Gui-Sheng Zou | 2019 | Acta Metallurgica Sinica(English Letters)2019，32，3： | 1 |
| 17 | Snapshot of Structural Variations in the Tibetan Wild Boar Genome at Single-Nucleotide Resolution显示文摘Genomic structural variations(SVs),particularly insertions,deletions and inversions,can contribute to the heterogeneity of millions of nucleotides within a genome,and are likely to make an important contribution to biological diversity and phenotypic variation(Alkan et al.,2011;Bickhart and Liu,2014).With the rapid development of the next-generation sequencing technologies and the new assembly methodologies,the | Lei Chen Long Jin Mingzhou Li Shilin Tian Tiandong Che Qianzi Tang Jing Lan Zhi Jiang Ruiqiang Li Yiren Gu Xuewei Li Jinyong Wang | 2014 | Journal of Genetics and Genomics2014，41，12： | 1 |
| 18 | 2021皮肤红斑狼疮的诊断、治疗和长期管理指南显示文摘皮肤红斑狼疮(CLE)是一种炎症性自身免疫性疾病,其分型较多,包括急性、亚急性、慢性和间歇性CLE。其中,慢性CLE可以进一步分为红斑狼疮(LE)的几个亚型,如盘状LE、疣状LE、深在性LE、冻疮样LE和Blaschko线状LE等。为了给皮肤科医生和风湿科医生提供CLE的诊断、治疗和长期管理的实用指导建议,本证据和共识指南根据卫生保健实践指南的报告条目(国际RIGHT工作组)目录编制,并在国际实践指南注册平台注册。在亚洲皮肤科学会(ADA)、亚洲皮肤病性病学会(AADV)以及中华医学会皮肤性病学分会(CSD)红斑狼疮研究中心的共同努力下,来自亚洲、美洲、欧洲等16个国家或地区的25名皮肤科医生、7名风湿科医生、1名红斑狼疮领域专家和2名方法学家参与了本指南的制定。所有建议均取得了32名医生中至少80%的同意。作为共识,CLE的诊断主要基于临床和组织病理学表现的评估,并且通过对全身多系统损伤的评估,排除系统性红斑狼疮(SLE)。外用糖皮质激素和钙调磷酸酶抑制剂是局部CLE的一线治疗。对于泛发或严重的CLE皮损和/或局部耐药的病例,可以合并全身治疗,包括抗疟药和/或短期全身使用糖皮质激素。值得注意的是,抗疟药是所有类型CLE的一线全身治疗药物,同样可用于妊娠期患者和儿童。二线治疗用药包括沙利度胺、类维生素A类药物、氨苯砜和甲氨蝶呤,而霉酚酸酯是三线治疗用药。最后,脉冲染料激光或手术可作为四线治疗,用于局部以及发生在不可修饰部位的慢性、难治性CLE皮损。贝利尤单抗亦可作为四线治疗用药,用于活动性SLE患者的泛发性CLE皮损或糖皮质激素逐渐减量期间复发的急性CLE。对于疾病的管理,患者教育和长期随访是必要的。建议在每次随访时适当评估疾病活动度、皮肤和其他器官损伤、生活质量、合并症及可能发生的不良事件。 | Qianjin Lu Hai Long Steven Chow Syarief Hidayat Retno Danarti Yulianto Listiawan Danqi Deng Qing Guo Hong Fang Juan Tao Ming Zhao Leihong Xiang Nan Che Fen Li Hongjun Zhao Chak Sing Lau Fong Cheng Ip King Man Ho Arnelfa C.Paliza Chan Vicheth Kiran Godse Soyun Cho Chew Swee Seow Yoshiki Miyachi Tran Hau Khang Rataporn Ungpakorn Hassan Galadari Rashmikant Shah Kehu Yang Youwen Zhou Carlo Selmi Amr HSawalha Xuan Zhang Yaolong Chen Chrang-Shi Lin 姚文鑫 | 2022 | 中国合理用药探索2022，19，10： | 1 |
| 19 | Development of phosphonate-terminated magnetic mesoporous silica nanoparticles for pH-controlled release of doxorubicin and improved tumor accumulation显示文摘In this study,phosphonate-terminated magnetic mesoporous nanoparticles(pMMSNs)was designed by incorporation of MNPs in the center of mesoporous silica nanoparticles(MSNs)and followed by grafting phosphonate group on to the surface of MMSNs.The carrier exhibited a typical superparamagnetic feature and the saturation magnetization was 4.89 emu/g measured by vibrating sample magnetometer(VSM).pMMSNs had a spherical morphology and a pore size of 2.2 nm.FromN2 adsorption-desorption analysis,pMMSNs had a surface area of 613.4 m^(2)/g and a pore volume of 0.78 cm^(3)/g.Phosphonate modification improved the colloidal stability of MMSNs,and the hydrodynamic diameter of pMMSNs was around 175 nm.The hydrophilic phosphonate group significantly enhanced the negative surface charge of MMSNs from -19.3 mV to -28.8 mV pMMSNs with more negative surface charge had a 2.3-fold higher drug loading capacity than that of MMSNs.In addition,the rate and amount of release of doxorubicin(DOX)from DOX/pMMSNs was pH-dependent and increased with the decrease of pH.At pH 7.4,the release amount was quite low and only approximately 17wt%ofDOXwasreleasedin48h.AtpH5.0and3.0,the release rate increased significantly and the release amount achieved 31 wt%and 60 wt%in 48 h,respectively.To evaluate the magnetic targeting performance ofpMMSNs,FITC labeledpMMSNswas injected into mice bearing S180 solid tumor.FITC labeledpMMSNscontrolled by an external magnetic field showed higher tumor accumulation and lower normal tissue distribution. | Erxi Che Long Wan Ying Zhang Qinfu Zhao Xiling Han Jia Li Jia Liu Siling Wang | 2014 | Asian Journal of Pharmaceutical Sciences2014，9，6： | 0 |
| 20 | Zero-waste emission design of sustainable and programmable actuators显示文摘Moisture-responsive actuators are widely used as energy-harvesting devices due to their excellent ability to spontaneously and continuously convert external energy into kinetic energy.However,it remains a challenge to sustainably synthesize moisture-driven actuators.Here,we present a sustainable zero-waste emission methodology to prepare soft actuators using carbon nano-powders and biodegradable polymers through a water evaporation method.Due to the water solubility and recyclability of the matrixes employed here,the entire synthetic process achieves zero-waste emission.Our composite films featured strong figures of merit and capabilities with a 250◦maximum bending angle under 90%relative humidity.Programmable motions and intelligent bionic applications,including walkers,smart switches,robotic arms,flexible excavators,and hand-shaped actuators,were further achieved by modulating the geometry of the actuators.This sustainable method for actuators’fabrication has great potential in large-scale productions and applications due to its advantages of zero-waste emission manufacturing,excellent recyclability,inherent adaptive integration,and low cost. | Linchao Sun Lixuan Che Ming Li William George Neal Xu Leng Yaojia Long Yifeng Jia Yunhu Gao Matteo Palma Yao Lu | 2023 | SusMat2023，3，2： | 0 |
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