|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 肾脏病学的新创意:“肾脏疾病:改善全球预后”(KDIGO)显示文摘慢性肾脏病(CKD)是世界范围的医疗和公共卫生问题,并开始呈现流行性的特点.美国肾脏数据系统(USRDS)的数据提示,终末期肾衰的发病率呈上升趋势,因此对于这一问题的重视日益增加.根据近期USRDS登记系统提供的资料,世界范围内需要肾脏替代治疗(RRT)的终末期肾病(ESRD)患者数目持续上升,其中我国台湾、美国和日本最多(254~365人/100万人)[1].卡塔尔和巴斯克地区的儿童患病率最高,分别为33.7人/100万人和22.7人/100万人;在大于等于20岁患者中患病率最高的是卡塔尔、美国和台湾.在欧洲,德国的患病率最高,2000年为175人/100万人.在RRT仍在发展中的东欧,报道的患病率低于西欧[2]. | Norbert Lameire Garabed Eknoyan Rashad Barsoum Kai-Uwe Eckardt Adeera Levin Nathan Levin Francesco Locatelli Alison Macleod Raymond Vanholder Rowan Walker Haiyan Wang 张路霞 王海燕 | 2005 | 中华肾脏病杂志2005，21，12： | 19 |
| 2 | Intestinal dendritic cells in the pathogenesis of inflammatory bowel disease显示文摘The gastrointestinal tract harbors a large number and diverse array of commensal bacteria and is an important entry site for pathogens.For these reasons,the intestinal immune system is uniquely dedicated to protect against infections,while avoiding the development of destructive inflammatory responses to the microbiota.Several models have been proposed to explain how the immune system discriminates between,and appropriately responds to,commensal and pathogenic microorganisms.Dendritic cells(DCs)and regulatory T cells(Treg)are instrumental in maintaining immune homeostasis and tolerance in the gut.DCs are virtually omnipresent and are remarkably plastic,having the ability to adapt to the influences of the microenvironment.Different DC populations with partially overlapping phenotypic and functional properties have been described in different anatomical locations.DCs in the draining mesenteric lymph nodes,in the intestinal lamina propria and in Peyer's patches partake both in the control of intestinal inflammation and in the maintenance of gut tolerance.In this respect,gutresident DCs and macrophages exert tolerogenic functions as they regularly encounter and sense commensal bacteria.In contrast,migrating DC subsets that are recruited to the gut as a result of pathogenic insults initiate immune responses.Importantly,tolerogenic DCs act by promoting the differentiation and expansion of Treg cells that efficiently modulate gut inflammation,as shown both in preclinical models of colitis and in patients with inflammatory bowel disease(IBD).This article reviews the phenotypic and functional features of gut DC subsets and discusses the current evidence underpinning the DC contribution to the pathogenesis of the major clinical subtypes of human IBD.It also addresses the potential clinical benefit derived from DC targeting either in vivo or in vitro. | Sergio Rutella Franco Locatelli | 2011 | World Journal of Gastroenterology2011，17，33： | 13 |
| 3 | A new governance approach for multi-firm projects: Lessons from Olkiluoto 3 and Flamanville 3 nuclear power plant projects显示文摘 | Inkeri Ruuska Tuomas Ahola Karlos Artto Giorgio Locatelli Mauro Mancini | 2010 | International Journal of Project Management2010，，6： | 2 |
| 4 | Nruroendovrine control of growth hormone secretion 显示文摘 | Eugenio E Muller Vittorio Locatelli Daniela Cocchi | 1999 | Physiol Rev1999，70，2： | 1 |
| 5 | Neuroendocrine control of growth hormone secretion显示文摘 | Muller EE Locatelli V Cocchi D | 1999 | Physiological Reviews1999，79，： | 1 |
| 6 | A moderate transfusion regimen may reduce iron loading in 13-thalassemia major without producing excessive expansion of erythropoiesis显示文摘 | Cazzola M Borgna-Pignatti C Locatelli F | 1997 | Transfusion1997，37，： | 1 |
| 7 | Somatic stem cell research for neural repair:Current evidence and emerging perspectives显示文摘 | Corti S Locatelli F Papadimitriou D | 2004 | J Cell Mol Med2004，8，3： | 1 |
| 8 | Is it the agent or the blood pressure level that matters for renal and vascular protection in ehronie nephropathies? 显示文摘 | LOCATELLI F DEL VECCHIO L POZZONI P | 2005 | Kidney Int Suppl2005，，93： | 1 |
| 9 | Detection of liver metastases with pulse inversion harmonic imaging: Preliminary results显示文摘 | L. Dalla Palma M. Bertolotto E. Quaia M. Locatelli | 1999 | European Radiology1999，，3： | 1 |
| 10 | Resting heartrate and the risk of heart failure in healthy adults: theRotterdam Study显示文摘 | Nanchen D* Leening MJ Locatelli I | 2013 | Circ Heart Fail2013，6，3： | 1 |
| 11 | A randomized,double-blind,placebo-controlled study to assess the efficacy and safety of cinacalcet HCl in participants with CKD not receiving dialysis显示文摘 | Chonchol M Locatelli F Abboud HE | | 0，，： | 1 |
| 12 | Predictors of adverse perinatal outcome in twins delivered at <?37 weeks显示文摘 | Patrizia Vergani Anna Locatelli Marta Ratti Antonietta Scian Giulia Zangheri John Pezzullo Alessandro Ghidini | 2004 | Journal of Maternal-Fetal and Neonatal Medicine2004，，6： | 1 |
| 13 | Effects of MCP-1 inhibition by bindarit therapy in a rat model of polycystic kidney disease显示文摘 | Zoja C Coma D Locatelli M | 2015 | Nephron2015，129，1： | 1 |
| 14 | Peginesa- tide in patients with anemia undergoing hemodialysis 显示文摘 | Fishbane S Schiller B Locatelli F | 2013 | N Engl J Med2013，368，4： | 1 |
| 15 | A randomised controlled trial of ursodeoxycholic acid and S-adenosyl-l-methionine in the treatment of gestational cholestasis显示文摘 | Roncaglia N Locatelli A Arreghini A | 2004 | BJOG2004，111，1： | 1 |
| 16 | Cardiovascular disease in chronic renal failure: The challenge continues显示文摘 | Locatelli F Marcelli D Conte F | 2000 | Nephrol Dial Transplant2000，15，： | 1 |
| 17 | The importance of diabetic nephropathy in current nephrological practice 显示文摘 | Locatelli F Canaud B Eckardt KU | 2003 | Nephrol Dial Transplant2003，18，9： | 1 |
| 18 | Predictors of perinatal survival in a cohort of pregnancies with severe oligohydramnios due to premature rupture of membranes at 《 26 weeks managed with serial amnioinfusions显示文摘 | Locatelli A Ghidini A Verderio M | 2006 | Eur J Obstet Gynecol Reprod Biol2006，128，12： | 1 |
| 19 | Use of recombinanthuman granuloeyte colony-stimulating factor in children given allogeneic born marrow transplantation for acute or chronic leukemia显示文摘 | Locatelli F Pession A Zecca M | 1996 | Bone Marrow Transplant1996，17，1： | 1 |
| 20 | The importance of substance P and calcitonin gene related peptide as vasodilator neuropeptide during acute phase of experimental posthemorrhagic vasospasm 显示文摘 | Locatelli M | 2000 | J Neurosurg Sci2000，44，4： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员