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| 1 | Complications of radiofrequency ablation of hepatic tumors:Frequency and risk factors显示文摘Radiofrequency ablation(RFA)has become an important option in the therapy of primary and secondary hepatic tumors.Surgical resection is still the best treatment option,but only a few of these patients are candidates for surgery:multilobar disease,insufficient liver reserve that will lead to liver failure after resection,extra-hepatic disease,proximity to major bile ducts and vessels,and co-morbidities.RFA has a low mortality and morbidity rate and is considered to be safe.Thus,complications occur and vary widely in the literature.Complications are caused by thermal damage,direct needle injury,infection and the patient’s co-morbidities.Tumor type,type of approach,number of lesions,tumor localization,underlying hepatic disease,the physician’s experience,associated hepatic resection and lesion size have been described as factors significantly associated with complications.The physician in charge should promptly recognize high-risk patients more susceptible to complications,perform a close post procedure follow-up and manage them early and adequately if they occur.We aim to describe complications from RFA of hepatic tumors and their risk factors,as well as a few techniques to avoid them.This way,others can decrease their morbidity rates with better outcomes. | Alexandre Zanchenko Fonseca Stephanie Santin Luiz Guilherme Lisboa Gomes Jaques Waisberg Marcelo Augusto Fontenelle Ribeiro Jr. | 2014 | World Journal of Hepatology2014，6，3： | 24 |
| 2 | Primary prophylaxis of variceal bleeding in patients with cirrhosis:A comparison of different strategies显示文摘Patients with cirrhosis and esophageal varices bleed at a yearly rate of 5%-15%,and,when variceal hemorrhage develops,mortality reaches 20%.Patients are deemed at high risk of bleeding when they present with medium or large-sized varices,when they have red signs on varices of any size and when they are classified as Child-Pugh C and have varices of any size.In order to avoid variceal bleeding and death,individuals with cirrhosis at high risk of bleeding must undergo primary prophylaxis,for which currently recommended strategies are the use of traditional non-selective beta-blockers(NSBBs)(i.e.,propranolol or nadolol),carvedilol(a NSBB with additional alpha-adrenergic blocking effect)or endoscopic variceal ligation(EVL).The superiority of one of these alternatives over the others is controversial.While EVL might be superior to pharmacological therapy regarding the prevention of the first bleeding episode,either traditional NSBBs or carvedilol seem to play a more prominent role in mortality reduction,probably due to their capacity of preventing other complications of cirrhosis through the decrease in portal hypertension.A sequential strategy,in which patients unresponsive to pharmacological therapy would be submitted to endoscopic treatment,or the combination of pharmacological and endoscopic strategies might be beneficial and deserve further investigation. | Ângelo Zambam de Mattos Carlos Terra Alberto Queiroz Farias Paulo Lisboa Bittencourt Alliance of Brazilian Centers for Cirrhosis Care–the ABC Group | 2021 | World Journal of Gastrointestinal Endoscopy2021，13，12： | 8 |
| 3 | Relationship between Physical and Chemical Soil Attributes and Plant Species Diversity in Tropical Mountain Ecosystems from Brazil显示文摘Although the high diversity of plant species in the rupestrian fields has been primarily attributed to the existence of a set of distinct habitats, few studies support this assertion. The present study aimed to further investigate the relationship between physical and chemical attributes of soils with the diversity of plant species in this unique ecosystem. The rupestrian field is a unique vegetation formation that covers some of the southeastern Brazilian mountains in the transition of the Atlantic rain forest and the Cerrado(savanna). Different habitats occur according to soil characteristics(e.g., presence of rocks, sand, fertility, hydrology, etc.). These attributes ultimately influence the vegetation that is highly adapted to the harsh edaphic and climatic mountain conditions. Five distinct habitats were studied by us: rocky outcrops, peat bogs, sandy bogs, quartz gravel fields, and 'cerrado'(savanna). A floristic survey indicated that four families are found at greater frequency: Poaceae, Asteraceae, Cyperaceae, and Leguminosae. The greatest diversity of plant species was found in the rocky outcrops habitat, followed by cerrado, peat bog, quartz gravel grassland, and sandy bogs, respectively. The main difference in the floristic composition among these habitats was related to the dominant species. Trachypogon spicatus(Poaceae) was the most dominant species in the rocky outcrops, Axonopus siccus(Poaceae) in the peat bogs, Lagenocarpus rigidus(Cyperaceae) in the sandy bogs, Schizachyrium tenerum(Poaceae) in the cerrado, while Vellozia sp. 8(Velloziaceae) dominated the vegetation in the quartz gravel grassland. This study demonstrated that physical and chemical soil properties strongly related the diversity of plant species occurring in the different habitats of rupestrian fields. | Ferna de CARVALHO Edward Luis GODOY Francy J. G. LISBOA Fatima Maria de Souza MOREIRA Francisco Adriano de SOUZA Ricardo Luis Louro BERBARA G Wilson FERNES | 2014 | Journal of Mountain Science2014，11，4： | 7 |
| 4 | Assessing the inter-annual variability of separation distances around odour sources to protect the residents from odour annoyance显示文摘In recent years, there has been a growing concern about potential impacts on public health and wellbeing due to exposure to environmental odour. Separation distances between odour-emitting sources and residential areas can be calculated using dispersion models, as a means of protecting the neighbourhood from odour annoyance. This study investigates the suitability of using one single year of meteorological input data to calculate reliable direction-dependent separation distances. Accordingly, we assessed and quantified the inter-annual variability of separation distances at two sites with different meteorological conditions, one in Brazil and the other in Austria. A 5-year dataset of hourly meteorological observations was used for each site. Two odour impact criteria set in current regulations were selected to explore their effect on the separation distances. The coefficient of variation was used as a statistical measure to characterise the amount of annual variation. Overall,for all scenarios, the separation distances had a low degree of inter-annual variability(mean coefficient of variation values from 8% to 21%). Reasonable agreements from year to year were therefore observed at the two sites under investigation, showing that one year of meteorological data is a good compromise to achieve reliable accuracy. This finding can provide a more cost-effective solution to calculate separation distances in the vicinity of odour sources. | Marlon Brancher Martin Piringer Davide Franco Paulo Belli Filho Henrique De Melo Lisboa Gunther Schauberger | 2019 | Journal of Environmental Sciences2019，31，5： | 6 |
| 5 | Renal failure in cirrhosis: Emerging concepts显示文摘Acute renal failure, now termed acute kidney injury(AKI), is frequently found in patients with cirrhosis. The occurrence of AKI, irrespective of the underlying cause, is associated with reduced in-hospital, 3-mo and 1-year survival. Hepatorenal syndrome is associated with the worst outcome among AKI patients with cirrhosis. Several definitions for AKI that have been proposed are outlined and evaluated in this paper. Among these, the International Club for Ascites-AKI criteria substantially strengthen the quality of early diagnosis and intervention according to underlying cause of AKI. | Paulo Lisboa Bittencourt Alberto Queiroz Farias Carlos Terra | 2015 | World Journal of Hepatology2015，7，21： | 5 |
| 6 | Cumulative positive fluid balance is a risk factor for acute kidney injury and requirement for renal replacement therapy after liver transplantation显示文摘AIM To analyze whether fluid overload is an independent risk factor of adverse outcomes after liver transplantation(LT).METHODS One hundred and twenty-one patients submitted to LT were retrospectively evaluated.Data regarding perioperative and postoperative variables previously associated with adverse outcomes after LT were reviewed.Cumulative fluid balance(FB) in the first 12 h and 4 d after surgery were compared with major adverse outcomes after LT.RESULTS Most of the patients were submitted to a liberal approach of fluid administration with a mean cumulative FBover 5 L and 10 L,respectively,in the first 12 h and 4 d after LT.Cumulative FB in 4 d was independently associated with occurrence of both AKI and requirement for renal replacement therapy(RRT)(OR = 2.3;95%CI:1.37-3.86,P = 0.02 and OR = 2.89;95%CI:1.52-5.49,P = 0.001 respectively).Other variables on multivariate analysis associated with AKI and RRT were,respectively,male sex and Acute Physiology and Chronic Health Disease Classification System(APACHE II) levels and sepsis or septic shock.Mortality was shown to be independently related to AST and APACHE II levels(OR = 2.35;95%CI:1.1-5.05,P = 0.02 and 2.63;95%CI:1.0-6.87,P = 0.04 respectively),probably reflecting the degree of graft dysfunction and severity of early postoperative course of LT.No effect of FB on mortality after LT was disclosed.CONCLUSION Cumulative positive FB over 4 d after LT is independently associated with the development of AKI and the requirement of RRT.Survival was not independently related to FB,but to surrogate markers of graft dysfunction and severity of postoperative course of LT. | Liana Codes Ygor Gomes de Souza Ricardo Azevedo Cruz D'Oliveira Jorge Luiz Andrade Bastos Paulo Lisboa Bittencourt | 2018 | World Journal of Transplantation2018，8，2： | 4 |
| 7 | Corticosteroids for severe influenza pneumonia: A critical appraisal显示文摘Influenza pneumonia is associated with high number of severe cases requiring hospital and intensive care unit(ICU) admissions with high mortality. Systemic steroids are proposed as a valid therapeutic option even though its effects are still controversial. Heterogeneity of published data regarding study design, population demographics, severity of illness, dosing, type and timing of corticosteroids administered constitute an important limitation for drawing robust conclusions. However, it is reasonable to admit that, as it was not found any advantage of corticosteroid therapy in so diverse conditions, such beneficial effects do not exist at all. Its administration is likely to increase overall mortality and such trend is consistent regardless of the quality as well as the sample size of studies. Moreover it was shown that corticosteroids might be associated with higher incidence of hospital-acquired pneumonia and longer duration of mechanical ventilation and ICU stay. Finally, it is reasonable to conclude that corticosteroids failed to demonstrate any beneficial effects in the treatment of patients with severe influenza infection. Thus its current use in s evere influenza pneumonia should be restricted to very selected cases and in the setting of clinical trials. | Wagner Luis Nedel David Garcia Nora Jorge Ibrain Figueira Salluh Thiago Lisboa Pedro Póvoa | 2016 | World Journal of Critical Care Medicine2016，5，1： | 3 |
| 8 | 利用电阻率和探地雷达(GPR)法进行污染场地地球物理勘查——巴西圣保罗州里贝朗普雷图市润滑油废物处理区研究实例显示文摘地球物理方法在圈定废物处理区污染范围方面非常有效,有助于提高测深项目和监测井安装的效率。在研究区内,再精炼润滑油废弃物已堆积了近25年。为了开展此项研究,在该区开挖了4个总体积约25000m^3的沟槽。在沟槽底部和两侧未使用任何保护衬砌。本文目的是,评价电阻率和探地雷达法在描述巴西圣保罗州里贝朗普雷图市这种润滑油废物处理区污染的潜力,该润滑油废物处理区位于Serra Geral组玄武岩倾复带和Botucatu组砂岩的地质单元。采用二维剖面图显示方式揭示地球物理勘查结果。地球物理勘查结果表明:沟槽下部区域的电阻率(小于185Ωm)反映碳氢化合物中细菌的活动,与在以往文献中报告的由碳氢化合物引起污染的多个场地内观测结果类似。通过探地雷达法(GPR)可确定沟槽的几何形状。通过直接取样(监测井中地下水和土壤的化学分析)可证实污染的存在。在土样分析中发现,样品中存在多种低浓度的多环芳香碳氢化合物(PAH),这些化合物主要为萘和菲。通过水样分析证实地下水受到铅污染。在勘查期间使用的地球物理方法,为这种润滑油废物处理区研究提供了一种极好的环境描述手段,且在类似地区的研究中也可应用这些地球物理方法。 | Alexandre Lisboa Lago Vagner Roberto Elis 赵玉军(翻译) 武毅(校对) | 2009 | 水文地质工程地质技术方法动态2009，，3： | 3 |
| 9 | Resveratrol attenuates oxidative stress and prevents steatosis and hypertension in obese rats programmed by early weaning显示文摘 | Juliana G. Franco Patrícia C. Lisboa Natália S. Lima Taline A.S. Amaral Nayara Peixoto-Silva Angela C. Resende Elaine Oliveira Magna C.F. Passos Egberto G. Moura | 2013 | The Journal of Nutritional Biochemistry2013，，6： | 2 |
| 10 | Metabolic surgery and intestinal gene expression:Digestive tract and diabetes evolution considerations显示文摘AIM: To investigate the effects of bariatric surgery on metabolic parameters, incretin hormone secretion, and duodenal and ileal mucosal gene expression.METHODS: Nine patients with type 2 diabetes mellitus(T2DM), chronic serum hyperglycemia for more than2 years, and a body mass index(BMI) of 30-35 kg/m2 underwent metabolic surgery sleeve gastrectomy with transit bipartition between May 2011 and December2011. Blood samples were collected pre and 3, 6 and12 mo postsurgery. Duodenal and ileal mucosa samples were collected pre- and 3 mo postsurgery. Pre- and postoperative blood samples were collected in the fasting state before ingestion of a standard meal(520kcal) and again 30, 60, 90, and 120 min after the mealto determine hemoglobin A1c(HbA1c) levels and the lipid profile, which consisted of triglyceride and total cholesterol levels. Intestinal gene expression of p53 and transforming growth factor(TGF)-β was analyzed using quantitative reverse-transcription PCR. Gastric inhibitory polypeptide(GIP) and glucagon-like peptide-1(GLP-1)were quantified using the enzyme-linked immunoassay method and analyzed pre- and postoperatively.Student's t test or repeated measurements analysis of variance with Bonferroni corrections were performed as appropriate.RESULTS: BMI values decreased by 15.7% within the initial 3 mo after surgery(31.29 ± 0.73 vs 26.398± 0.68, P < 0.05) and then stabilized at 22% at 6mo postoperative, resulting in similar values 12 mo postoperatively(20-25 kg/m2). All of the patients experienced improved T2 DM, with 7 patients(78%)achieving complete remission(HbA1c < 6.5%), and 2patients(22%) achieving improved diabetes(HbA1c< 7.0% with or without the use of oral hypoglycemic agents). At 3 mo postoperatively, fasting plasma glucose had also decreased(59%)(269.55 ±18.24 mg/dL vs 100.77 ± 3.13 mg/dL, P < 0.05)with no further significant changes at 6 or 12 mo postoperatively. In the first month postoperatively,there was a complete withdrawal of hypoglycemic medications in all patients, who were taking at least2 hypoglycemic drugs preoperatively. GLP-1 levels significantly increased after surgery(149.96 ± 31.25 vs220.23 ± 27.55)(P < 0.05), while GIP levels decreased but not significantly. p53 gene expression significantly increased in the duodenal mucosa(P < 0.05, 2.06 fold)whereas the tumor growth factor-β gene expression significantly increased(P < 0.05, 2.52 fold) in the ileal mucosa after surgery.CONCLUSION: Metabolic surgery ameliorated diabetes in all of the patients, accompanied by increased antiproliferative intestinal gene expression in non-excluded segments of the intestine. | Marcos Ricardo da Silva Rodrigues Marco Aurelio Santo Giovani Marino Favero Elaine Cristina Vieira Roberto Ferreira Artoni Viviane Nogaroto Egberto Gaspar de Moura Patricia Lisboa Fabio Quirillo Milleo | 2015 | World Journal of Gastroenterology2015，21，22： | 2 |
| 11 | Exploiting dynamic reaction cell inductively coupled plasma mass spectrometry (DRC-ICP-MS) for sequential determination of trace elements in blood using a dilute-and-shoot procedure显示文摘 | Bruno Lemos Batista Jairo Lisboa Rodrigues Juliana Andrade Nunes Vanessa Cristina de Oliveira Souza Fernando Barbosa | 2009 | Analytica Chimica Acta2009，，1： | 1 |
| 12 | Decreases in procaleitonin and C-reactive protein are strong predictors of survival in ventilator-associated pneumonia 显示文摘 | SELIGMAN R MEISNER M LISBOA T C | 2006 | Crit Care2006，10，5： | 1 |
| 13 | Analysis of the safety and efficacy of imra-arterial thrombolytie ther- apy in ischemic stroke 显示文摘 | LISBOA RC JOVANOVIE BD ALBERTS MJ | 2002 | Stroke2002，33，： | 1 |
| 14 | Spectrum of practicein the diagnosis of nosocomial pneumonia in patients requiringmechanical ventilation in European intensive care units 显示文摘 | Koulenti D Lisboa T Brun-Buisson C | 2009 | CritCare Med2009，37，8： | 1 |
| 15 | Critically ill patients with cancer and sepsis :clinical course and prog- nostic factors显示文摘 | Rosolem MM Rabello LS Lisboa T | 2012 | J Crit Care2012，27，3： | 1 |
| 16 | A care bundle approach for prevention of ventilator-associated pneumonia 显示文摘 | Rello J Afonso E Lisboa T | 2013 | C]in Microbiol Infect2013，19，4： | 1 |
| 17 | Analysis of the safety and efficacy of intra-arterial thrombolytic therapy in ischemic stroke显示文摘 | Jovanovic B D Alberts M J | 2002 | Stroke2002，33，12： | 1 |
| 18 | A randomized trial of dental brushing for preventing ventilator-associated pneumonia显示文摘 | Pobo A Lisboa T Rodriguez A | 2009 | Chest2009，136，2： | 1 |
| 19 | C-reactive protein correlates with bacterial load and appropriate antibiotic therapy in suspected ventilator-associated pneumonia显示文摘 | Lisboa T Seligman R Diaz E | | 0，，： | 1 |
| 20 | Effects of estradiol benzoate on 5'-iodothyronine deiodinase activities in female rat anterior pituitary gland, liver and thyroid 显示文摘 | Lisboa PC Curty FH Moreira RM | 1997 | Braz J Med Biol Res1997，30，12： | 1 |
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