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| 1 | Oxygen Requirements for the Cambrian Explosion显示文摘Hypoxic tolerance experiments may be helpful to constrain the oxygen requirement for animal evolution. Based on literature review, available data demonstrate that fishes are more sensitive to hypoxia than crustaceans and echinoderms, which in turn are more sensitive than annelids, whilst mollusks are the least sensitive. Mortalities occur where O_2 concentrations are below 2.0 mg/L, equivalent to saturation with oxygen content about 25% PAL(present atmospheric level). Therefore, the minimal oxygen requirement for maintaining animal diversity since Cambrian is determined as 25% PAL. The traditional view is that a rise in atmospheric oxygen concentrations led to the oxygenation of the ocean, thus triggering the evolution of animals. Geological and geochemical studies suggest a constant increase of the oxygen level and a contraction of anoxic oceans during Ediacaran–Cambrian transition when the world oceans experienced a rapid diversification of metazoan lineages. However, fossil first appearances of animal phyla are obviously asynchronous and episodic, showing a sequence as: basal metazoans>lophotrochozoans>ecdysozoans and deuterostomes. According to hitherto known data of fossil record and hypoxic sensitivity of animals, the appearance sequence of different animals is broadly consistent with their hypoxic sensitivity: animals like molluscs and annelids that are less sensitive to hypoxia appeared earlier, while animals like echinoderms and fishes that are more sensitive to hypoxia came later. Therefore, it is very likely that the appearance order of animals is corresponding to the increasing oxygen level and/or the contraction of anoxic oceans during Ediacaran–Cambrian transition. | Xingliang Zhang Linhao Cui | 2016 | Journal of Earth Science2016，27，2： | 6 |
| 2 | SUMOylation-modified Pelota-Hbs1 RNA surveillance complex restricts the infection of potyvirids in plants显示文摘RNA quality control nonsense-mediated decay is involved in viral restriction in both plants and animals.However,it is not known whether two other RNA quality control pathways,nonstop decay and no-go decay,are capable of restricting viruses in plants.Here,we show that the evolutionarily conserved Pelota–Hbs1 complex negatively regulates infection of plant viruses in the family Potyviridae(termed potyvirids),the largest group of plant RNA viruses that accounts for more than half of the viral crop damage worldwide.Pelota enables the recognition of the functional G1-2A6-7 motif in the P3 cistron,which is conserved in almost all potyvirids.This allows Pelota to target the virus and act as a viral restriction factor.Furthermore,Pelota interacts with the SUMO E2-conjugating enzyme SCE1 and is SUMOylated in planta.Blocking Pelota SUMOylation disrupts the ability to recruit Hbs1 and inhibits viral RNA degradation.These findings reveal the functional importance of Pelota SUMOylation during the infection of potyvirids in plants. | Linhao Ge Buwei Cao Rui Qiao Hongguang Cui Shaofang Li Hongying Shan Pan Gong Mingzhen Zhang Hao Li Aiming Wang Xueping Zhou Fangfang Li | 2023 | Molecular Plant2023，16，3： | 2 |
| 3 | The C_(6)D_(6)detector system on the Back-n beam line of CSNS显示文摘Introduction The neutron capture cross sections are very important in the field of nuclear device design and basic physics research.Hydrogen-free liquid scintillator such as C_(6)D_(6)detectors are widely used in the neutron capture cross-sectional measurements for the low neutron sensitivity and fast time response.The Back-n white neutron source at China Spallation Neutron Source is the first spallation white neutron source in China,and it is suitable for neutron capture cross-sectional measurement.Materials and methods A C_(6)D_(6)detector system was built in the Back-n experimental station.The pulse height weighting technique was used to determine the system’s detection efficiency.The response to gamma rays of the C_(6)D_(6)detector was measured,and the energy resolution function was determined.Monte Carlo simulation with Geant4 code was carried out to get the weighting function of this C_(6)D_(6)detector system.Additionally,the systematic uncertainty of the weighting function was also determined.Conclusion According to the experimental and simulation results,this C_(6)D_(6)detector system can be used to measure neutron capture cross section. | Jie Ren Xichao Ruan Jie Bao Guangyuan Luan Wei Jiang Qi An Huaiyong Bai Ping Cao Qiping Chen Yonghao Chen Pinjing Cheng Zengqi Cui Ruirui Fan Changqing Feng Minhao Gu Fengqin Guo Changcai Han Zijie Han Guozhu He Yongcheng He Yuefeng He Hanxiong Huang Weiling Huang Xiru Huang Xiaolu Ji Xuyang Ji Haoyu Jiang Hantao Jing Ling Kang Mingtao Kang Bo Li Lun Li Qiang Li Xiao Li Yang Li Yang Li Rong Liu Shubin Liu Xingyan Liu Yinglin Ma Changjun Ning Binbin Qi Zhaohui Song Hong Sun Xiaoyang Sun Zhijia Sun Zhixin Tan Hongqing Tang Jingyu Tang Pengcheng Wang Qi Wang Taofeng Wang Yanfeng Wang Zhaohui Wang Zheng Wang Jie Wen Zhongwei Wen Qingbiao Wu Xiaoguang Wu Xuan Wu Likun Xie Yiwei Yang Han Yi Li Yu Tao Yu Yongji Yu Guohui Zhang Jing Zhang Linhao Zhang Liying Zhang Qingmin Zhang Qiwei Zhang Xianpeng Zhang Yuliang Zhang Zhiyong Zhang Yingtan Zhao Liang Zhou Zuying Zhou Danyang Zhu Kejun Zhu Peng Zhu | 2019 | Radiation Detection Technology and Methods2019，3，3： | 1 |
| 4 | Detector development at the Back-n white neutron source显示文摘Purpose Back-n is a white neutron beamline at China spallation neutron source,which was established in the year of 2018.It is a powerful facility for nuclear data measurement,neutron detector calibration,and radiation effect research.Method A series of detectors were built for different experiments,including beam monitoring,beam profile measurement,neutron induced secondaries(fission fragments,light charged particles and gamma)cross section measurement,and neutron resonance radiography,etc.A common digitization electronics and a cluster-based DAQ were developed for these detector systems.Most detectors have been employed at Back-n and serviced for experiments from the beginning of the beamline running.Results and conclusion As an overview of detectors of Back-n,the details of the detector design and the experiment performing are described in this paper.Some developing systems,e.g.,MTPC and B-MCP,are also included. | Fan Ruirui Li Qiang Bao Jie Li Yang Liu Rong Jiang Wei Ren Jie Zhang Qiwei Cao Ping Gu Minhao Ren Zhizhou Yi Han Tang Jingyu An Qi Bai Haofan Bai Jiangbo Chen Qiping Chen Yonghao Chen Zhen Cui Zengqi Fan Anchuan Feng Changqing Feng Fanzhen Gao Keqing Han Changcai Han Zijie He Guozhu He Yongcheng Hong Yang Hu Yiwei Huang Hanxiong Jia Weihua Jiang Haoyu Jiang Zhijie Jin Zhengyao Kang Ling Li Bo Li Chao Li Gong Li Jiawen Li Xiao Liu Jie Liu Shubin Luan Guangyuan Ning Changjun Qi Binbin Ruan Xichao Song Zhaohui Sun Kang Tan Zhixin Tang Shengda Wang Pengcheng Wang Zhaohui Wen Zhongwei Wu Xiaoguang Wu Xuan Xie Likun Yang Yiwei Yu Yongji Zhang Guohui Zhang Linhao Zhang Mohan Zhang Xianpeng Zhang Yuliang Zhang Yue Zhang Zhiyong Zhao Maoyuan Zhou Luping Zhou Zhihao Zhu Kejun The CSNS Back-n Collaboration | 2023 | Radiation Detection Technology and Methods2023，7，2： | 0 |
| 5 | Effect ofβ-cyclodextrin on the hemocompatibility of heparin-modified PMP hollow fibrous membrane for Extracorporeal Membrane Oxygenation(ECMO)显示文摘In this paper,modified membranes containingβ-cyclodextrin(β-CD)and heparin coatings were prepared on the surface of poly-4-methyl-1-pentene(PMP)hollow fibrous membrane using the high strength adhesion of polydopamine(PDA).In this paper,β-CD was added to increase the hemocompatibility of the PMP hollow fibrous membranes and the stability of the heparin coating.The uniformity of the heparin coating withβ-CD addition was better than that of the groups withoutβ-CD.After seven days of saline rinsing,the surface of the modified membranes withβ-CD addition still had a large amount of heparin present,which was more stable compared to the control group.After surface modification,the modified membrane changed from hydrophobic to hydrophilic.Importantly,the protein adsorption,platelet adhesion,and hemolysis rates of the modified membranes were significantly reduced compared with the pristine membranes.The APTT values were also significantly increased.The results showed that the modified membranes with the addition ofβ-CD had better hydrophilicity,can maintain the stability of heparin coating for a long time,and finally showed good hemocompatibility. | Xingrui Zhong Ting He Zhaohui Wang Yawei Wang Linhao Li Zhaoliang Cui | 2023 | Medicine in Novel Technology and Devices2023，，2： | 0 |
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