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12019新型冠状病毒基因组特征和流行病学:病毒起源和受体结合的意义显示文摘研究者对来自9例新型冠状病毒肺炎住院患者的支气管肺泡灌洗液样本和培养的分离株进行了下一代测序。从这些个体中获得了严重急性呼吸综合征-冠状病毒2(severe acute respiratory syndrome-coronavirus 2,SARS-CoV-2)的完整和部分基因组序列。利用Sanger测序连接病毒重叠群以获得全长基因组,cDNA末端快速扩增确定终端区。对这些SARSCoV-2基因组和其他冠状病毒基因组进行了系统进化分析,以确定该病毒的进化史并有助于推断其可能的起源。刘青(译) 刘莉(审校) Lu R Zhao X Li J Niu P Yang B Wu H Wang W Song H Huang B Zhu N Bi Y Ma X Zhan F Wang L Hu T Zhou H Hu Z Zhou W Zhao L Chen J Meng Y Wang J Lin Y Yuan J Xie Z Ma J Liu WJ Wang D Xu W Holmes EC Gao GF Wu G Chen W Shi W Tan W 2020中华高血压杂志2020,28,3:516
2Recent advances in endovascular techniques for management of acute nonvariceal upper gastrointestinal bleeding显示文摘Over the past two decades,transcatheter arterial embolization has become the first-line therapy for the management of upper gastrointestinal bleeding that is refractory to endoscopic hemostasis.Advances in catheter-based techniques and newer embolic agents, as well as recognition of the effectiveness of minimally invasive treatment options,have expanded the role of interventional radiology in the management of hemorrhage for a variety of indications,such as peptic ulcerbleeding,malignant disease,hemorrhagic Dieulafoy lesions and iatrogenic or trauma bleeding.Transcatheter interventions include the following:selective embolization of the feeding artery,sandwich coil occlusion of the gastroduodenal artery,blind or empiric embolization of the supposed bleeding vessel based on endoscopic findings and coil pseudoaneurysm or aneurysm embolization by three-dimensional sac packing with preservation of the parent artery.Transcatheter embolization is a fast,safe and effective,minimally invasive alternative to surgery when endoscopic treatment fails to control bleeding from the upper gastrointestinal tract.This article reviews the various transcatheter endovascular techniques and devices that are used in a variety of clinical scenarios for the management of hemorrhagic gastrointestinal emergencies.Romaric F Loffroy Basem A Abualsaud Ming D Lin Pramod P Rao 2011World Journal of Gastrointestinal Surgery2011,3,7:28
3欧洲和中国的心脏与肾脏远程缺血预适应研究:一项随机对照试验显示文摘远程缺血预适应(remote ischemic preconditioning,RIPC)对经皮冠状动脉介入治疗(percutaneous coronary intervention,PCI)术后造影剂肾病(contrast-induced nephropathy,CIN)的潜在保护作用尚待确定。该研究为双盲、随机、安慰剂对照的多中心研究,纳入年龄〈85岁,肾清除率为30~60mL/(min·1.73m^2)的有临床适应证的患者,除了直接PCI外均按1∶1给予RIPC或标准治疗。主要终点是CIN的发生率。次要终点是围手术期心肌梗死(peri-procedural myocardial infarction,PMI)的发生率。刘青 叶鹏 Moretti C Cerrato E Cavallero E Lin S Rossi ML Picchi A Sanguineti F Ugo F Palazzuoli A Bertaina M Presbitero P Shao-Liang C Pozzi R Giammaria M Limbruno U Lefèvre T Gasparetto V Garbo R OmedèP Sheiban I Escaned J Biondi-Zoccai G Gaita F Perl L D'Ascenzo F 2018中华高血压杂志2018,26,4:3
4Charge control and mobility studies for an AlGaN/GaN high electron mobility transistor显示文摘Zhang Y Zhang H B Lin G D Chen P, Yuan Y Z, Tsai K R 0,,:3
5胆固醇酯转移蛋白基因的蛋白质截断型变异体与冠状动脉性心脏病风险的关系显示文摘随机对照试验结果表明,抑制胆固醇酯转运蛋白(cholesteryl ester transfer protein,CETP)的疗法并不能降低冠状动脉性心脏病(coronary heart disease,CHD)的发生风险。研究失败的可能原因包括靶目标无效、靶目标外小分子的不良反应和随机对照设计因素影响等。在编码药物靶点的基因中具有天然存在的遗传变异,以此为基础,人类研究可以深入了解针对基因产物的治疗的潜在功效和安全性。Nomura A Won HH Khera AV Takeuchi F Ito K McCarthy S Emdin CA Klarin D Natarajan P Zekavat SM Gupta N Peloso GM Borecki IB Teslovich TM Asselta R Duga S Merlini PA Correa A Kessler T Wilson JG Bown MJ Hall AS Braund PS Carey DJ Murray MF Kirchner HL Leader JB Lavage DR Manus JN Hartze DN Samani NJ Schunkert H Marrugat J Elosua R McPherson R Farrall M Watkins H Juang JJ Hsiung CA Lin SY Wang JS Tada H Kawashiri MA Inazu A Yamagishi M Katsuya T Nakashima E Nakatochi M Yamamoto K Yokota M Momozawa Y Rotter JI Lander ES Rader DJ Danesh J Ardissino D Gabriel S Willer CJ Abecasis GR Saleheen D Kubo M Kato N Ida Chen YD Dewey FE Kathiresan S 刘莉 叶鹏 2017中华高血压杂志2017,25,9:2
6显示文摘 Zhang H B Lin G D 1997Carbon1997,35,:1
7Genetic diversity and biogeography of Cunninghamia konishii ( Cupressaeeae ) , an island species in Taiwan:a comparison with Cunninghamia lanceolata, a mainland species in China显示文摘Chung J D Lin T P Tan Y C 2004Molecular Phy- logeneties and Evolution2004,33,:1
8The tumor suppressor candidate p33ING1b mediates repair of UV-damaged DNA显示文摘Cheung KJ Mitchell D Lin P 2001Cancer Res2001,61,:1
9Enriched back-arc basin basalts from the northern Mariana Trough:Implications for the magmatic evolution of back-arc basins显示文摘STERN R J LIN P MORRIS J D 1990Earth and Planetary Science Letters1990,100,:1
10Optical coherence tomography显示文摘HUANG D SWANSON E A LIN C P 1991254(5035):1178-11811991,254,5035:1
11New briaranes fromthe octocorals Briareum excavatum (Briareidae) andJunceella fragilis ( Ellisellidae) 显示文摘Sung P J Lin M R Su Y D 2008Tetrahedron2008,64,11:1
12The mathematical models of the basic en- tities of multi-axis serial orthngonal machine tools using a modified Denavit-Hartenberg notation显示文摘TSAI C Y LIN P D 2009Int J Adv Manuf Technol2009,42,:1
13Single-crystal- line sodium-doped p-type ZnO and ZnMgO nanowires via eombination of thin-film and nano techniques 显示文摘HE H P LIN S S YUAN G D 2011Jour- nal of Physical Chemistry: C2011,115,39:1
14Perfluorinated Compounds in Aquatic Organisms at Various Trophic Levels in a Great Lakes Food Chain显示文摘Kurunthachalam Kannan Lin Tao Ewan Sinclair Stephanie D Pastva Dave J Jude John P Giesy 2005Archives of Environmental Contamination and Toxicology2005,,4:1
15Preparation and properties of nano-silica modified nega- tive acrylate photoresist 显示文摘Lee C K Don T M Lai W C Chert C C Lin D J Cheng L P 2008Thin Solid Films2008,516,23:1
16Anti-inflammatory activity of Chinese medicinal vine plants 显示文摘Li R W Lin G D Myers S P 2003J Ethnopharmacol2003,85,:1
17Growth of carbon nanotubes by catalytic decomposition of CH4 or CO on a Ni-MgO catalyst显示文摘Chen P Zhang H B Lin G D 1997Carbon1997,35,:1
18Optical coherence tomography显示文摘Huang D Swanson E A Lin C P 1991Science1991,254,5035:1
19A SERS study of thio- cyanate adsorption on Au-core Pal-shell nanoparticle film electrodes显示文摘Fang P P Li J F Lin X D 2012Journal of Electroanalytical Chemistry2012,665,:1
20Mechanisms of PVDF membrane formation by immersion - precipitation in soft (1 octanol) and harsh (water) nonsolvents 显示文摘Young T H Cheng L P Lin D J 1999Polymer1999,40,19:1
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