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		题名	作者	年代	出处	被引量
	1	胆固醇酯转移蛋白基因的蛋白质截断型变异体与冠状动脉性心脏病风险的关系显示文摘随机对照试验结果表明,抑制胆固醇酯转运蛋白(cholesteryl ester transfer protein,CETP)的疗法并不能降低冠状动脉性心脏病(coronary heart disease,CHD)的发生风险。研究失败的可能原因包括靶目标无效、靶目标外小分子的不良反应和随机对照设计因素影响等。在编码药物靶点的基因中具有天然存在的遗传变异,以此为基础,人类研究可以深入了解针对基因产物的治疗的潜在功效和安全性。	Nomura A Won HH Khera AV Takeuchi F Ito K McCarthy S Emdin CA Klarin D Natarajan P Zekavat SM Gupta N Peloso GM Borecki IB Teslovich TM Asselta R Duga S Merlini PA Correa A Kessler T Wilson JG Bown MJ Hall AS Braund PS Carey DJ Murray MF Kirchner HL Leader JB Lavage DR Manus JN Hartze DN Samani NJ Schunkert H Marrugat J Elosua R McPherson R Farrall M Watkins H Juang JJ Hsiung CA Lin SY Wang JS Tada H Kawashiri MA Inazu A Yamagishi M Katsuya T Nakashima E Nakatochi M Yamamoto K Yokota M Momozawa Y Rotter JI Lander ES Rader DJ Danesh J Ardissino D Gabriel S Willer CJ Abecasis GR Saleheen D Kubo M Kato N Ida Chen YD Dewey FE Kathiresan S 刘莉叶鹏	2017	中华高血压杂志2017，25，9：	2
	2	Cancer-related transcriptional targets of the circadian gene NPAS2 identified by genome-wide ChIP-on-chip analysis显示文摘	Yi CH Zheng T Leaderer D		0，，02：	1
	3	Relationship between sulfate aerosol and visibility显示文摘	LEADERER B P HOLFORD T R STOLWIJK J A	1979	Journal of the Air Pollution Control Association1979，29，2：	1
	4	Adjunctive therapiesin Nutritional support显示文摘	Leader L M Jonas C R	1997	Nutrition1997，13，9：	1
	5	A Computational Geometry Approach to Automated Pulmonary Fissure Segmentation in CT Examinations显示文摘	Pu J T Leader J K Zheng B	2009	IEEE Transactions on Medical Imaging2009，28，5：	1
	6	A novel protein containing a death domain that interacts with Fas/Apo-1(CD95) in yeast and causes cell death 显示文摘	STRANGE R B I LEADER P LEE T H	1995	Cell1995，81，：	1
	7	MODIS Level 1B Product User's Guide显示文摘	Toller G N Isaacman A Leader M T		0，，：	1
	8	Genetic and epigenetic as- sociations of circadian gene TIMELESS and breast cancer risk 显示文摘	Fu A Leaderer D Zheng T	2012	Mol Carcinog2012，51，12：	1
	9	An automated CT based lung nodule detection scheme using geometric analysis of signed distance field显示文摘	Pu J T Zheng B Leader K	2008	Med Phys2008，35，8：	1
	10	Caneer-rclated transcription- al targets of the circadian gene NPAS2 identified by genome-wide ChiP-on-chip analysis显示文摘	Yi CH Zheng T Leaderer D	2009	Cancer Lett2009，284，2：	1
	11	Glutamine and the gastrointestinal显示文摘	Ziegler T R Bazargan N Leader L M	2000	Curr Opin Clin Nutr Metab Care2000，3，5：	1
	12	Prospects for Group Processes and Intergroup Relations Research: A Review of 70 Years' Progress 显示文摘	De Moura G R Leader T Pelletier J Abrams D	2008	Group Processes and Intergroup Relations2008，11，4：	1
	13	CD4^+ lymphocytes and gamma interferon predominate in local immune responses in early experimental syphilis显示文摘	Leader B T Godornes C VanVoorhis W C	2007	Infect Immun2007，75，6：	1
	14	Glutamine and the gastrointestinal tract显示文摘	Ziegler T R Bazargan N Leader	2000	Curr Opin Clin Nutr Metab Care2000，3，5：	1
	15	Diet and nutrient in- takes and risk of non-Hodgkin' s lymphoma in Connecticut women显示文摘	Zheng T Holford TR Leaderer B	2004	Am J Epidemio12004，159，：	1
	16	Genetic andepigenetic association studies suggest a role of microRNAbiogenesis gene exportin-5 CXP05) in breast tumorigenesis显示文摘	Leaderer D Hoffman AE Zheng T	2011	Int J Mol Epidemiol Genet2011，2，1：	1
	17	Relationship between sulfate aerosol and visibility显示文摘	Leaderer B P Holford T R Stolwijk J A J		0，，02：	1
	18	Creatinine-clearance estimates for predicting gentamicin pharmacokinetic values in obese patients显示文摘	Leader WG Tsubaki T Chandler MHH	1994	American Journal of Hospital Pharmacy1994，51，17：	1

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