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| 1 | Segmentation of Hematoxylin-Eosin stained breast cancer histopathological images based on pixel-wise SVM classifier显示文摘Hematoxylin-Eosin(HE) staining is the routine diagnostic method for breast cancer(BC), and large amounts of HE stained histopathological images are available for analysis. It is emergent to develop computational methods to efficiently and objectively analyze these images, with the aim of providing potentially better diagnostic and prognostic information for BC. This work focuses on analyzing our in-house HE stained histopathological images of breast cancer tissues. Since tumor nests(TNs) and stroma morphological characteristics can reflect the biological behaviors of breast invasive ductal carcinoma(IDC), accurate segmentation of TNs and the stroma is the first step towards the subsequent quantitative analysis. We first propose a method based on the pixel-wise support vector machine(SVM) classifier for segmenting TNs and the stroma, then extract four morphological characters related to the TNs from the images and investigate their relationships with the patients' 8-year disease free survival(8-DFS). The evaluation result shows that the classification based segmentation method is able to distinguish between TNs and stroma with 87.1% accuracy and 80.2% precision,suggesting that the proposed method is promising in segmenting HE stained IDC histopathological images. The Kaplan-Meier survival curves show that three morphological characters(number of TNs, total perimeter, and average area of TNs) in the images have statistical correlations with 8-DFS of the patients, illustrating that the segmented images can help to identify new morphological factors in IDC TNs for the prediction of BC prognosis. | QU AiPing CHEN JiaMei WANG LinWei YUAN JingPing YANG Fang XIANG QingMing MASKEY Ninu YANG GuiFang LIU Juan LI Yan | 2015 | Science China(Information Sciences)2015,58,9: | 12 |
| 2 | Near-perfect fidelity polarization-encoded multilayer optical data storage based on aligned gold nanorods显示文摘Encoding information in light polarization is of great importance in facilitating optical data storage(ODS)for information security and data storage capacity escalation.However,despite recent advances in nanophotonic techniques vastly en-hancing the feasibility of applying polarization channels,the data fidelity in reconstructed bits has been constrained by severe crosstalks occurring between varied polarization angles during data recording and reading process,which gravely hindered the utilization of this technique in practice.In this paper,we demonstrate an ultra-low crosstalk polarization-en-coding multilayer ODS technique for high-fidelity data recording and retrieving by utilizing a nanofibre-based nanocom-posite film involving highly aligned gold nanorods(GNRs).With parallelizing the gold nanorods in the recording medium,the information carrier configuration minimizes miswriting and misreading possibilities for information input and output,respectively,compared with its randomly self-assembled counterparts.The enhanced data accuracy has significantly im-proved the bit recall fidelity that is quantified by a correlation coefficient higher than 0.99.It is anticipated that the demon-strated technique can facilitate the development of multiplexing ODS for a greener future. | Linwei Zhu Yaoyu Cao Qiuqun Chen Xu Ouyang Yi Xu Zhongliang Hu Jianrong Qiu Xiangping Li | 2021 | Opto-Electronic Advances2021,4,11: | 9 |
| 3 | Molecular behaviors in thin film lubrication——Part two: Direct observation of the molecular orientation near the solid surface显示文摘Over the past twenty years, thin film lubrication(TFL) theory has been used to characterize the molecular behaviors in lubrication films thinner than 100 nm, effectively bridging the gap between elastohydrodynamic lubrication and boundary lubrication. Unfortunately, to date, the TFL molecular model proposed in 1996 has not been directly proven by experimental detection. Herein, a method based on surface-enhanced Raman spectroscopy was developed to show both the packing and orienting of liquid molecules in the TFL regime. By trapping liquid crystal molecules between a structured silver surface and a glass surface, molecular ordering states dominated by shear effect and surface effect were successfully distinguished. A nanosandwich structure consisting of an adsorbed layer, an ordered-molecule layer, and a fluid layer was demonstrated. Molecule imaging in TFL was achieved. Our results illustrate the molecular behaviors and lubrication mechanism in nanoconfined films and facilitate the lubrication design of nanoelectromechanical and microelectromechanical systems. | Ming GAO Haoyu LI Liran MA Yuan GAO Linwei MA Jianbin LUO | 2019 | Friction2019,7,5: | 5 |
| 4 | Strategies of Removing Residual Lithium Compounds on the Surface of Ni-Rich Cathode Materials显示文摘Ni-rich cathode materials have become one of the most promising cathode materials for advanced high-energy Li-ion batteries(LIBs)owing to their high specific capacity.However,Ni-rich cathode materials are sensitive to the trace H2O and CO2 in the air,and tend to react with them to generate LiOH and Li2COg at the particle surface region(named residual lithium compounds,labeled as RLCs).The RLCs will deteriorate the comprehensive performances of Ni-rich cathode materials and make trouble in the subsequent manufacturing process of electrode,including causing low initial coulombic efficiency and poor storage property,bringing about potential safety hazards,and gelatinizing the electrode slurry.Therefore,it is of considerable significance to remove the RLCs.Researchers have done a lot of work on the corresponding field,such as exploring the formation mechanism and elimination methods.This paper investigates the origin of the surface residual lithium compounds on Ni-rich cathode materials,analyzes their adverse effects on the per-formance and the subsequent electrode production process,and summarizes various kinds of feasible methods for removing the RLCS.Finally,we propose a new research direction of eliminating the lithium residuals after comparing and summing up the above.We hope this work can provide a reference for alleviating the adverse effects of residual lithium compounds for Ni-rich cathode materials'industrial production. | Yuefeng Su Linwei Li Gang Chen Lai Chen Ning Li Yun Lu Liying Bao Shi Chen Feng Wu | 2021 | Chinese Journal of Chemistry2021,39,1: | 4 |
| 5 | Centrifugal model test on a riverine landslide in the Three Gorges Reservoir induced by rainfall and water level fluctuation显示文摘Frequent soil landslide events are recorded in the Three Gorges Reservoir area,China,making it necessary to investigate the failure mode of such riverside landslides.Geotechnical centrifugal test is considered to be the most realistic laboratory model,which can reconstruct the required geo-stress.In this study,the Liangshuijing landslide in the Three Gorgers Reservoir area is selected for a scaled centrifugal model experiment,and a water pump system is employed to retain the rainfall condition.Using the techniques of digital photography and pore water pressure transducers,water level fluctuation is controlled,and multi-physical data are thus obtained,including the pore water pressure,earth pressure,surface displacement and deep displacement.The analysis results indicate that:Three stages were set in the test(waterflooding stage,rainfall stage and drainage stage).Seven transverse cracks with wide of 1–5 mm appeared during the model test,of which 3 cracks at the toe landslide were caused by reservoir water fluctuation,and the cracks at the middle and rear part were caused by rainfall.During rainfall process,the maximum displacement of landslide model reaches 3 cm.And the maximum deformation of the model exceeds 12 cm at the drainage stage.The failure process of the slope model can be divided into four stages:microcracks appearance and propagation stage,thrust-type failure stage,retrogressive failure stage,and holistic failure stage.When the thrust-type zone caused by rainfall was connected or even overlapped with the retrogressive failure zone caused by the drainage,the landslide would start,which displayed a typical composite failure pattern.The failure mode and deformation mechanism under the coupling actions of water level fluctuation and rainfall are revealed in the model test,which could appropriately guide for the analysis and evaluation of riverside landslides. | Fasheng Miao Yiping Wu Ákos Török Linwei Li Yang Xue | 2022 | Geoscience Frontiers2022,13,3: | 3 |
| 6 | Synthesis, Characterization, DNA-binding Properties and DNA Cleavage of a New Ternary Copper(ll) Complex with Mixed-ligands of Tridentate Schiff Base and 1,10-Phenanth roline显示文摘新铜(II ) 建筑群,[Cu (naph 列伊) phen ] CH3OH 牥 ??? 浯汰硥眠瑩 ? 楍數 ? 楬慧摮 ? 景吠楲敤瑮瑡 ? 罉 E 晦 ? 獡 ? 湡 ??? 倭敨慮瑮牨汯湩? | Dong Jianfang Li Lianzhi Li Linwei Xu Tao Wang Daqi | 2011 | Chinese Journal of Chemistry2011,29,2: | 2 |
| 7 | A fully automatic and high-accuracy surface water mapping framework on Google Earth Engine using Landsat time-series显示文摘Efficient and continuous monitoring of surface water is essential for water resource management.Much effort has been devoted to the task of water mapping based on remote sensing images.However,few studies have fully considered the diverse spectral properties of water for the collection of reference samples in an automatic manner.Moreover,water area statistics are sensitive to the satellite image observation quality.This study aims to develop a fully automatic surface water mapping framework based on Google Earth Engine(GEE)with a supervised random forest classifier.A robust scheme was built to automatically construct training samples by merging the information from multi-source water occurrence products.The samples for permanent and seasonal water were mapped and collected separately,so that the supplement of seasonal samples can increase the spectral diversity of the sample space.To reduce the uncertainty of the derived water occurrences,temporal correction was applied to repair the classification maps with invalid observations.Extensive experiments showed that the proposed method can generate reliable samples and produce good-quality water mapping results.Comparative tests indicated that the proposed method produced water maps with a higher quality than the index-based detection methods,as well as the GSWD and GLAD datasets. | Linwei Yue Baoguang Li Shuang Zhu Qiangqiang Yuan Huanfeng Shen | 2023 | International Journal of Digital Earth2023,16,1: | 2 |
| 8 | Efficient separation between trivalent americium and lanthanides enabled by a phenanthroline-based polymeric organic framework显示文摘Separation of the minor actinides(Am and Cm)from lanthanides in high-level liquid wastes(HLLW)is one of the most challenging chemical separation tasks known owing to their chemical similarities and is highly significant in nuclear fuel reprocessing plants because it could practically lead to sustainable nuclear energy by closing the nuclear fuel cycle.The solid phase extraction is proposed to be a possible strategy but all reported sorbent materials severely suffer from limited stability and/or efficiency caused by the harsh conditions of high acidity coupled with intense irradiation.Herein,a phenanthroline-based polymeric organic framework(PhenTAPB-POF)was designed and tested for the separation of trivalent americium from lanthanides for the first time.Due to its fully conjugated structure,PhenTAPB-POF exhibits previously unachieved stability under the combined extreme conditions of strong acids and high irradiation field.The americium partitioning experiment indicates that PhenTAPB-POF possesses an ultrahigh adsorption selectivity towards Am(Ⅲ)over lanthanides(e.g.,SFAm(Ⅲ)/Eu(Ⅲ)=3326)in highly acidic simulated HLLW and relatively fast adsorption kinetics in both static and dynamic experiments.Am(Ⅲ)can be almost quantitatively eluted from the PhenTAPB-POF packed-column using a concentrated nitric acid elution.The high stability and superior separation performance endow PhenTAPB-POF with the promising alternative for separating minor actinides over lanthanides from highly acidic HLLW streams. | Afshin Khayambashi Long Chen Xue Dong Kai Li Zhipeng Wang Linwei He Suresh Annam Lixi Chen Yaxing Wang Matthew V.Sheridan Chao Xu Shuao Wang | 2022 | Chinese Chemical Letters2022,33,7: | 1 |
| 9 | Numerical research on lid-driven cavity flows using a three-dimensional lattice Boltzmann model on non-uniform meshes显示文摘A lattice Boltzmann model combined with curvilinear coordinate is proposed for lid-driven cavity three-dimensional (3D) flows. For particle velocity distribution, the particle collision process is performed in physical domain, and the particle streaming process is carried out in the corresponding computational domain, which is transferred from the physical domain using interpolation method. For the interpolation calculation, a second-order upwind interpolation method is adopted on internal lattice nodes in flow fields while a second-order central interpolation algorithm is employed at neighbor-boundary lattice nodes. Then the above-mentioned model and algorithms are used to numerically simulate the 3D flows in the lid-driven cavity at Reynolds numbers of 100, 400 and 1000 on non-uniform meshes. Various vortices on the x-y, y-z and x-z symmetrical planes are successfully predicted, and their changes in position with the Reynolds number increasing are obtained. The velocity profiles of u component along the vertical centerline and w component along the horizontal centerline are both in good agreement with the data in literature and the calculated results on uniform meshes. Besides, the velocity vector distributions on various cross sections in lid-driven cavity predicted on non-uniform meshes are compared with those simulated on uniform meshes and those in the literature. All the comparisons and validations show that the 3D lattice Boltzmann model and all the numerical algorithms on non-uniform meshes are accurate and reliable to predict effectively flow fields. | TANG XueLin SU YanWen WANG FuJun LI LinWei | 2013 | Science China(Technological Sciences)2013,56,9: | 1 |
| 10 | The development of low-carbon towns in China: concepts and practices 显示文摘 | LI Zheng CHANG Shiyao MA Linwei | 2012 | Energy2012,47,1: | 1 |
| 11 | Integrated energy strategy for the sustainable development of China显示文摘 | Linwei Ma Pei Liu Feng Fu Zheng Li Weidou Ni | 2011 | Energy2011,36,: | 1 |
| 12 | Inte- grated Energy Strategy for the Sustainable Development of China显示文摘 | Linwei Ma Pei Liu Feng Fu Zheng Li Weidou Ni | 2011 | Energy2011,,36: | 1 |
| 13 | Logarithmic mean Divisia index ( LMDI ) decomposition of coal consumption in China based on the energy allocation diagram of coal flows显示文摘 | Chong ChinHao Ma Linwei Li Zheng Ni Weidou Song Shizhong | 2015 | Energy2015,85,: | 1 |
| 14 | Integrated Energy Strategy for the Sustainable Development of China 显示文摘 | Linwei Ma Pei Liu Feng Fu Zheng Li Weidou Ni | 2011 | Energy2011,36,2: | 1 |
| 15 | Responses of the functional structure of soil microbial community to livestock grazing in the T ibetan alpine grassland显示文摘 | Yunfeng Yang Linwei Wu Qiaoyan Lin Mengting Yuan Depeng Xu Hao Yu Yigang Hu Jichuang Duan Xiangzhen Li Zhili He Kai Xue Joy van Nostrand Shiping Wang Jizhong Zhou | 2012 | Glob Change Biol2012,,2: | 1 |
| 16 | Research on Mechanical Product Development based on CAD Software显示文摘 | Funa Li Linwei Yang Ying Zeng | 2013 | International Journal of Technology Management2013,,1: | 1 |
| 17 | Oil development in China: Current status and future trends 显示文摘 | MA Linwei FU Feng LI Zheng | 2012 | Energy Policy2012,45,: | 1 |
| 18 | Stromal Cell- derived Factor-1 and its Receptor CXCR4 are Upregulated Expression in Degenerated Intervertebral Discs显示文摘 | Hua Zhang Li Zhang Linwei Chen | 2014 | Int J MedSci2014,11,3: | 1 |
| 19 | Thermochemistry on the coordination compounds of zinc sulphate with several L-α-amino acids 显示文摘 | DI Youying GAO Shengli LI Linwei | 2006 | Journal of Chemical Thermodynamics2006,38,7: | 1 |
| 20 | Estimating submarine groundwater discharge at a subtropical river estuary along the Beibu Gulf,China显示文摘In certain regions,submarine groundwater discharge(SGD)into the ocean plays a significant role in coastal material fluxes and their biogeochemical cycle;therefore,the impact of SGD on the ecosystem cannot be ignored.In this study,SGD was estimated using naturally occurring radium isotopes(^(223)Ra and ^(224)Ra)in a subtropical estuary along the Beibu Gulf,China.The results showed that the Ra activities of submarine groundwater were approximately 10 times higher than those of surface water.By assuming a steady state and using an Ra mass balance model,the SGD flux in May 2018 was estimated to be 5.98×10^(6) m^(3)/d and 3.60×10^(6) m^(3)/d based on 224Ra and 223Ra,respectively.At the same time,the activities of Ra isotopes fluctuated within a tidal cycle;that is,a lower activity was observed at high tide and a higher activity was seen at low tide.Based on these variations,the average tidal pumping fluxes of SGD were 1.15×10^(6) m^(3)/d and 2.44×10^(6) m^(3)/d with 224Ra and 223Ra,respectively.Tidaldriven SGD accounts for 24%-51%of the total SGD.Therefore,tidal pumping is an important driving force of the SGD in the Dafengjiang River(DFJR)Estuary.Furthermore,the SGD of the DFJR Estuary in the coastal zone contributes significantly to the seawater composition of the Beibu Gulf and the material exchange between land and sea. | Xilong Wang Kaijun Su Juan Du Linwei Li Yanling Lao Guizhen Ning Li Bin | 2021 | Acta Oceanologica Sinica2021,40,9: | 1 |