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| 1 | Near-perfect fidelity polarization-encoded multilayer optical data storage based on aligned gold nanorods显示文摘Encoding information in light polarization is of great importance in facilitating optical data storage(ODS)for information security and data storage capacity escalation.However,despite recent advances in nanophotonic techniques vastly en-hancing the feasibility of applying polarization channels,the data fidelity in reconstructed bits has been constrained by severe crosstalks occurring between varied polarization angles during data recording and reading process,which gravely hindered the utilization of this technique in practice.In this paper,we demonstrate an ultra-low crosstalk polarization-en-coding multilayer ODS technique for high-fidelity data recording and retrieving by utilizing a nanofibre-based nanocom-posite film involving highly aligned gold nanorods(GNRs).With parallelizing the gold nanorods in the recording medium,the information carrier configuration minimizes miswriting and misreading possibilities for information input and output,respectively,compared with its randomly self-assembled counterparts.The enhanced data accuracy has significantly im-proved the bit recall fidelity that is quantified by a correlation coefficient higher than 0.99.It is anticipated that the demon-strated technique can facilitate the development of multiplexing ODS for a greener future. | Linwei Zhu Yaoyu Cao Qiuqun Chen Xu Ouyang Yi Xu Zhongliang Hu Jianrong Qiu Xiangping Li | 2021 | Opto-Electronic Advances2021，4，11： | 9 |
| 2 | Tissue level microstructure and mechanical properties of the femoral head in the proximal femur of fracture patients显示文摘This study aims to investigate the regional variations of trabecular morphological parameters and mechanical parameters of the femoral head,as well as to determine the relationship between trabecular morphological and mechanical parameters.Seven femoral heads from patients with fractured proximal femur were scanned using a micro-CT system.Each femoral head was divided into 12 sub-regions according to the trabecular orientation.One 125 mm^3 trabecular cubic model was reconstructed from each sub-region.A total of 81 trabecular models were reconstructed,except three destroyed sub-regions from two femoral heads during the surgery.Trabecular morphological parameters,i.e.trabecular separation(Tb.Sp),trabecular thickness(Tb.Th),specific bone surface(BS/B V),bone volume fraction(BV/TV),structural model index(SMI),and degree of anisotropy(DA) were measured.Micro-finite element analyses were performed for each cube to obtain the apparent Young's modulus and tissue level von Mises stress distribution under 1%compressive strain along three orthogonal directions,respectively.Results revealed significant regional variations in the morphological parameters(P<0.05).Young's moduli along the trabecular orientation were significantly higher than those along the other two directions.In general,trabecular mechanical properties in the medial region were lower than those in the lateral region.Trabecular mechanical parameters along the trabecular orientation were significantly correlated with BS/BV,BV/TV,Tb.Th,and DA.In this study,regional variations of microstructural features and mechanical properties in the femoral head of patients with proximal femur fracture were thoroughly investigated at the tissue level.The results of this study will help to elucidate the mechanism of femoral head fracture for reducing fracture risk and developing treatment strategies for the elderly. | Linwei Lü Guangwei Meng He Gong Dong Zhu Jiazi Gao Yubo Fan | 2015 | Acta Mechanica Sinica2015，31，2： | 4 |
| 3 | A review on the forward osmosis applications and fouling control strategies for wastewater treatment显示文摘During the last decades,the utilization of osmotic pressure-driven forward osmosis technology for wastewater treatment has drawn great interest,due to its high separation efficiency,low membrane fouling propensity,high water recovery and relatively low energy consumption.This review paper summarizes the implementation of forward osmosis technology for various wastewater treatment including municipal sewage,landfill leachate,oil/gas exploitation wastewater,textile wastewater,mine wastewater,and radioactive wastewater.However,membrane fouling is still a critical issue,which affects water flux stability,membrane life and operating cost.Different membrane fouling types and corresponding fouling mechanisms,including organic fouling,inorganic fouling,biofouling and combined fouling are therefore further discussed.The fouling control strategies including feed pre-treatment,operation condition optimization,membrane selection and modification,membrane cleaning and tailoring the chemistry of draw solution are also reviewed comprehensively.At the end of paper,some recommendations are proposed. | Linwei Zhu Chun Ding Tengyang Zhu Yan Wang | 2022 | Frontiers of Chemical Science and Engineering2022，16，5： | 3 |
| 4 | A fully automatic and high-accuracy surface water mapping framework on Google Earth Engine using Landsat time-series显示文摘Efficient and continuous monitoring of surface water is essential for water resource management.Much effort has been devoted to the task of water mapping based on remote sensing images.However,few studies have fully considered the diverse spectral properties of water for the collection of reference samples in an automatic manner.Moreover,water area statistics are sensitive to the satellite image observation quality.This study aims to develop a fully automatic surface water mapping framework based on Google Earth Engine(GEE)with a supervised random forest classifier.A robust scheme was built to automatically construct training samples by merging the information from multi-source water occurrence products.The samples for permanent and seasonal water were mapped and collected separately,so that the supplement of seasonal samples can increase the spectral diversity of the sample space.To reduce the uncertainty of the derived water occurrences,temporal correction was applied to repair the classification maps with invalid observations.Extensive experiments showed that the proposed method can generate reliable samples and produce good-quality water mapping results.Comparative tests indicated that the proposed method produced water maps with a higher quality than the index-based detection methods,as well as the GSWD and GLAD datasets. | Linwei Yue Baoguang Li Shuang Zhu Qiangqiang Yuan Huanfeng Shen | 2023 | International Journal of Digital Earth2023，16，1： | 2 |
| 5 | Regional Variations in Trabecular Morphological Features of Femoral Head of Patients with Proximal Femoral Fractures显示文摘 | Linwei Lv Guangwei Meng He Gong Dong Zhu Jiazi Gao Meisheng Zhao | 2015 | Journal of Bionic Engineering2015，12，2： | 1 |
| 6 | Model for end-stage liver disease versus the Child-Pugh score in predicting the post-transplant 3-month and 1-year mortality in a cohort of Chinese recipients显示文摘 | Zhiyong Guo Xiaoshun He Linwei Wu Weiqiang Ju Anbin Hu Qiang Tai Dongping Wang Yi Ma Guodong Wang Xiaofeng Zhu Jiefu Huang | 2010 | Surgery Today2010，，1： | 1 |
| 7 | Model for end-stage liver disease versus the Child-Pugh score in predicting the post-transplant 3-month and 1-year mortality in a cohort of Chinese recipients显示文摘 | Zhiyong Guo Xiaoshun He Linwei Wu Weiqiang Ju Anbin Hu Qiang Tai Dongping Wang Yi Ma Guodong Wang Xiaofeng Zhu Jiefu Huang | 2010 | Surgery Today2010，，1： | 1 |
| 8 | An integrated multistage nanofocusing system显示文摘 | Chen Jiannong Zhu Linwei Wang Feifei | 2013 | Plasmonics2013，8，： | 1 |
| 9 | Engineering in-plane silicon nanowire springs for highly stretchable electronics显示文摘Crystalline silicon(c-Si) is unambiguously the most important semiconductor that underpins the development of modern microelectronics and optoelectronics, though the rigid and brittle nature of bulk c-Si makes it difficult to implement directly for stretchable applications. Fortunately, the one-dimensional(1 D) geometry, or the line-shape, of Si nanowire(SiNW) can be engineered into elastic springs, which indicates an exciting opportunity to fabricate highly stretchable 1 D c-Si channels. The implementation of such line-shape-engineering strategy demands both a tiny diameter of the SiNWs, in order to accommodate the strains under large stretching, and a precise growth location, orientation and path control to facilitate device integration. In this review, we will first introduce the recent progresses of an in-plane self-assembly growth of SiNW springs, via a new in-plane solid-liquidsolid(IPSLS) mechanism, where mono-like but elastic SiNW springs are produced by surface-running metal droplets that absorb amorphous Si thin film as precursor. Then, the critical growth control and engineering parameters, the mechanical properties of the SiNW springs and the prospects of developing c-Si based stretchable electronics, will be addressed. This efficient line-shape-engineering strategy of SiNW springs, accomplished via a low temperature batch-manufacturing, holds a strong promise to extend the legend of modern Si technology into the emerging stretchable electronic applications, where the high carrier mobility, excellent stability and established doping and passivation controls of c-Si can be well inherited. | Zhaoguo Xue Taige Dong Zhimin Zhu Yaolong Zhao Ying Sun Linwei Yu | 2018 | Journal of Semiconductors2018，39，1： | 1 |
| 10 | Multifunctional building elements for the construction of peptide drug conjugates显示文摘Engineering of smart building molecules is key basis in designing intelligent drug delivery systems.As an emerging sophisticated delivery system strategy,the powerful functions of peptide drug conjugates(PDCs)are attributed to a smart linker and multifunctional peptide domain.Peptides exhibit a wide range of functions and properties,including easy chemical synthesis and versatile modification,tunable biocompatibility,diversified self-assembled nanostructures,specific recognition/binding,and deep penetration of the cell membrane/extracellular matrix.In addition,various types of linkers enable PDCs to release drugs responsively according to the disease microen-vironment or treatment needs.Owing to these inherent advantages,PDCs have been widely explored for drug delivery.Herein,the latest developments in functional peptides and linkers commonly used to construct smart PDCs are reviewed.The purpose is to bring widespread attention to PDC design strategies and their contribution to fighting various diseases,as well as to provide guidance for research on intelligent PDC drug delivery systems. | Liu Xu Shan Xu Tangyong Xiang Heng Liu Linwei Chen Baoping Jiang Junhong Yao Hongliu Zhu Rongfeng Hu Zhipeng Chen | 2022 | Engineered Regeneration2022，3，1： | 0 |
| 11 | In Vitro Nanobody Library Construction by Using Gene Designated-Region Pan-Editing Technology显示文摘Camelid single-domain antibody fragments(nanobodies)are an emerging force in therapeutic biopharmaceuticals and clinical diagnostic reagents in recent years.Nearly all nanobodies available to date have been obtained by animal immunization,a bottleneck restricting the large-scale application of nanobodies.In this study,we developed three kinds of gene designatedregion pan-editing(GDP)technologies to introduce multiple mutations in complementarity-determining regions(CDRs)of nanobodies in vitro.Including the integration of G-quadruplex fragments in CDRs,which induces the spontaneous multiple mutations in CDRs;however,these mutant sequences are highly similar,resulting in a lack of sequences diversity in the CDRs.We also used CDR-targeting traditional gRNA-guided base-editors,which effectively diversify the CDRs.And most importantly,we developed the self-assembling gRNAs,which are generated by reprogrammed tracrRNA hijacking of endogenous mRNAs as crRNAs.Using base-editors guided by self-assembling gRNAs,we can realize the iteratively diversify the CDRs.And we believe the last GDP technology is highly promising in immunization-free nanobody library construction,and the full development of this novel nanobody discovery platform can realize the synthetic evolution of nanobodies in vitro. | Zhiyuan Niu Zhixia Luo Pengyang Sun Linwei Ning Xinru Jin Guanxu Chen Changjiang Guo Lingtong Zhi Wei Chang Wuling Zhu | 2022 | BioDesign Research2022，，1： | 0 |
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