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| 1 | 急性下呼吸道感染儿童的维生素D摄入显示文摘目的明确维生素D(Vit D)摄入是否与儿童急性下呼吸道感染(ALRI)相关。方法比较因毛细支气管炎或肺炎入院的5岁以下儿童和非配对、无呼吸道感染的同龄对照组儿童之间Vit D摄入的差别。197例儿童的看护人完成了问卷调查,内容包括人口统计变量、ALRI危险因素和饮食。评估ALRI与Vit D摄入及其他危险因素的相关性。结果 ALRI组儿童的平均Vit D摄入为每日48 IU/kg,对照组为每日60 IU/kg。当控制年龄、民族、社会经济地位、北部地区居住、母乳喂养、免疫接种和接触吸烟等因素时,Vit D每日摄入<80 IU/kg的儿童患ALRI的可能性比每日摄入≥80 IU/kg的儿童高4倍(OR=4.9;95%CI:1.5~16.4)。结论为了避免罹患ALRI等疾病,5岁以下儿童可能需要摄入比现在推荐量更高的Vit D剂量。因毛细支气管炎和肺炎是年幼儿童住院的最常见原因,增加Vit D的补充可能有重要的公共卫生保健意义。 | Karen S Leis J Dayre McNally Matthew R Montgomery Koravangattu Sankaran Chandima Karunanayake Alan M Rosenberg 马丽亚(译) | 2012 | 中国当代儿科杂志2012，14，1： | 25 |
| 2 | Submucosal tunneling and endoscopic resection of submucosal tumors at the esophagogastric junction显示文摘AIM: To evaluate the safety and efficacy of submucosal tunneling and endoscopic resection(STER) for treating submucosal tumors(SMTs).METHODS: Between August 2012 and October 2013, 21 patients with SMTs originating from the muscularis propria(MP) layer at the esophagogastric junction were treated by STER of their tumors. Key steps of the procedure include:(1) mucosal incision: a 2-cm longitudinal mucosal incision was made 5 cm proximal to the tumor;(2) submucosal tunneling: a submucosal tunnel was created 5 cm proximal to and 1 to 2 cm distal to the tumor;(3) tumor resection: the SMT was resected under direct endoscopic viewing;(4) hemostasis: while finishing the tumor resection, careful hemostasis of the MP defect and the tunnel was performed; and(5) mucosal closure: the mucosal incision site was closed by using hemostatic clips. During the operation, equipment used included a cap-fitted endoscope, an insulatedtip knife, a hook knife, hemostatic forceps, an injection needle, a snare, an endoclip, and a high-frequency generator. Carbon dioxide(CO2) insufflation was achieved by using a CO2 insufflator.RESULTS: The median age of the patients was 46.2 years(range, 35-59 years), and the majority were male(18 male vs 3 female). Complete resection rate was 100%(21/21). Eighteen lesions were resected en bloc. Mean tumor size was 23 mm(range, 10-40 mm), and mean procedure time was 62.9 min(range, 45-90 min). Pathological diagnosis of these tumors included leiomyoma(15 out of 21) and gastrointestinal stromal tumor(6 out of 21). Full-thickness MP resection was performed in 9 of 21 patients(42.9%), with mediastinal and subcutaneous emphysema occurring in all nine. At the completion of the procedure, all patients received closure of the incision with hemoclips. One patient required percutaneous drainage. The remaining 20patients required no further endoscopic or surgical intervention. There were no incidents of massive or delayed bleeding. The median follow-up period after the procedure was 6 mo(range, 2-14 mo). During followup, no patients were found to have residual or recurrent tumor or esophageal stricture.CONCLUSION: STER is safe, effective and feasible, which provides accurate histopathologic evaluation and curative treatment for SMTs originating from the MP layer at the esophagogastric junction. | De-Jun Zhou Zhen-Bo Dai Malcolm M Wells Dan-Lei Yu Jing Zhang Lei Zhang | 2015 | World Journal of Gastroenterology2015，21，2： | 20 |
| 3 | Amino acids 89-96 of Salmonella typhimunum Tlagell=n represent the major domain responsible for TLR5-independent adjuvanticity in the humoral immune response显示文摘 | Lei Zhang Zhiming Pan Xilong Kang Yun Yang Heekap Kang Na Zhang James M Rosati Xinan Jiao | 2015 | Cellular & Molecular Immunology2015，12，5： | 6 |
| 4 | Breast cancer in China显示文摘 | Lei Fan Kathrin Strasser-Weippl Jun-Jie Li Jessica St Louis Dianne M Finkelstein Ke-Da Yu Wan-Qing Chen Zhi-Ming Shao Paul E Goss | 2014 | Lancet Oncology2014，，7： | 4 |
| 5 | The potential drivers in forming avian biodiversity hotspots in the East Himalaya Mountains of Southwest China显示文摘Little has been published to describe or interpret Asian biodiversity hotspots,including those in the East Himalayan Mountains of Southwest China(HMSC),thus making necessary a review of the current knowledge.The Pliocene and Pleistocene geological and glacial histories of the Asian continent differ from those of Europe and North America,suggesting different mechanisms of speciation and extinction,and,thus,different responses to climate changes during the Quaternary glaciations.This short review summarizes potential drivers in shaping and maintaining high species richness and endemism of birds in the HMSC.The geographical location at the junction of different biogeographical realms,the wide range of habitats and climates along the extensive elevational range,the complex topography and the distinct geological history of this region have probably contributed to the evolution of an exceptionally species-rich and endemic-rich,specialized montane avian fauna.The Mountain systems in the HMSC may have provided refugia where species survived during the glacial periods and barriers for preventing species dispersal after the glacial periods.More studies are required to further test this refugia hypothesis by comparing more cold-tolerent and warm-tolerent species. | Fumin LEI Yanhua QU Gang SONG Per ALSTRÖM Jon FJELDSÅ | 2015 | Integrative Zoology2015，10，2： | 3 |
| 6 | Preparation and hybridization analysis of DNA/RNA from E. coli on microfabricated bioelectronic chips显示文摘 | Cheng Jing Sheldon E L Wu Lei Uribe A Gerrue L O Carrino J Heller M J O'Connell J P | | 0，，： | 2 |
| 7 | Urban Modification of Thunderstorms: An Observational Storm Climatology and Model Case Study for the Indianapolis Urban Region*显示文摘 | Niyogi Dev Pyle Patrick Lei Ming Arya S Pal Kishtawal Chandra M Shepherd Marshall Chen Fei Wolfe Brian | 2011 | Journal of Applied Meteorology and Climatology2011，，5： | 2 |
| 8 | 溶液环境中工作的扫描近场光学/荧光光谱显微术显示文摘我们采用双压电陶瓷片发展了一种切变力非光学检测探针-样品间距控制方法。基于这种方法,研制成能与倒置光学显微镜联合使用的扫描近场光学 荧光光谱显微系统,实现了在溶液环境中探针-样品间距的可靠控制和成像,获得了人体乳腺癌细胞内的近场荧光光谱。本文简要介绍该系统的工作原理以及利用该系统得到的实验结果。 | 商广义 朱传凤 王琛 万立骏 白春礼 Lei F H M Troyon H Morjani J F Angiboust M Manfait | 2003 | 电子显微学报2003，22，5： | 2 |
| 9 | Cervical artery dissection: Trauma and other potential mechanical trigger events显示文摘 | Stefan T. Engelter Caspar Grond-Ginsbach Tiina M. Metso Antti J. Metso Manja Kloss Stephanie Debette Didier Leys Armin Grau Jean Dallongeville Marie Bodenant Yves Samson Valeria Caso Alessandro Pezzini Leo H. Bonati Vincent Thijs Henrik Gensicke Juan J. M | 2013 | Neurology2013，，21： | 2 |
| 10 | Finite element analysis and design in stainless steel sheet forming and its experimental comparison显示文摘 | Lei L P Hwang S M Kang B S | 2001 | Journal of Materials Processing Technology2001，110，1： | 2 |
| 11 | Severe Hand, Foot, and Mouth Disease Associated with Coxsackievirus A6 - Alabama, Connecticut, California, and Nevada, November 201 1 - February 2012显示文摘 | McIntyre Mary G Stevens Kelly M Davidson Sherri Pippin Tina Magill Dagny Kulhanjian Julie A Kelly Daniel Greenhow Tara L Salas Maria L Yagi Shigeo Padilla Tasha Berumen Ricardo Glaser Carol Landry Marie Louise Lott Jason Chen Lei Paulson | 2012 | EN2012，，12： | 2 |
| 12 | Susceptibility to Photoinhibition of Three Deciduous Broadleaf Tree Species with Different Successional Traits Under Various Light Regimes 显示文摘 | Kital M Lei T T Koike T | 2000 | Plant Cell and Environment2000，23，： | 2 |
| 13 | Early diagnosis and therapeutic strategies for hepatocellular carcinoma:From bench to bedside显示文摘Hepatocellular carcinoma(HCC)is the fourth leading cause of cancer-related deaths worldwide.The prognosis of patients with HCC remains poor largely due to the late diagnosis and lack of effective treatments.Despite being widely used,alpha-fetoprotein serology and ultrasonography have limited diagnostic performance for early-stage HCC.The emergence of omics strategies has contributed to significant advances in the development of non-invasive biomarkers for the early diagnosis of HCC including proteins,metabolites,circulating tumor deoxyribonucleic acid,and circulating non-coding ribonucleic acid.Early diagnosis is beneficial to patients as it increases the proportion who can be treated with curative treatment,thus prolonging survival outcomes.Currently,multiple clinical trials involving locoregional,systemic therapies,and combinations of these modalities are changing therapeutic strategies for different stage HCC.Success in several preclinical trials that involve immunotherapeutic innovations has created the potential to complement and enforce other treatment strategies in the future.This review summarizes the most recent advances in noninvasive early molecular detection,current therapy strategies,and potential immunotherapeutic innovations of HCC. | Ming-Cheng Guan Ming-Da Wang Si-Yu Liu Wei Ouyang Lei Liang Timothy M Pawlik Qiu-Ran Xu Dong-Sheng Huang Feng Shen Hong Zhu Tian Yang | 2021 | World Journal of Gastrointestinal Oncology2021，13，4： | 2 |
| 14 | Occurrence and community composition of fast-growing Mycobacterium in soils contaminated with polycyclic aromatic hydrocarbons显示文摘 | Leys N M Ryngaert A Bastiaens L | 2005 | FEMS Microbiology Ecology2005，51，： | 1 |
| 15 | Effect of Mg-doping on the structural and electronic properties of LiCoO2: a first- principles investigation 显示文摘 | Shi S Ouyang C Lei M | 2007 | Journal of Power Sources2007，171，： | 1 |
| 16 | Supplemental microbial phytase improves bioavailability of dietary zinc to weanling pigs显示文摘 | kupk Miller E R ullrey D I Yokoyama M T | 1993 | Nutrition1993，，123： | 1 |
| 17 | A model for predicting aeolian sand drift entrainment on scales from paddock to region 显示文摘 | Shao Y Raupach M R Leys J F | 1996 | Soil Research1996，34，2： | 1 |
| 18 | DNA self-recognition in the structure of Potl bound to telomeric single-stranded DNA显示文摘 | Lei M Podell E R Baumann P | 2003 | Nature2003，426，6963： | 1 |
| 19 | Corrosion evaluation of microarc oxidation coatings formed on 2024 aluminium alloy 显示文摘 | Lei W Wang Y M Zhou Y | 2010 | Corrosion Science2010，52，8： | 1 |
| 20 | A collaborativecontrol system for mass customization manufacturing显示文摘 | TSENG M M LEI M SU Ch | 1997 | Annals of CIRP1997，46，37： | 1 |
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