|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Direct ex vivo analysis of dendritic cells in patients with hepatocellular carcinoma显示文摘瞄准:与肝细胞癌(HCC ) 从病人分析树枝状的房间(DC ) 的显型和功能以便在这疾病理解他们的角色。方法:骨髓的的树枝状的房间在 HCC 病人的外部血被枚举。从外部血的天真、刺激的骨髓的的树枝状的房间上的 CD80, CD83, CD86 和 HLA 医生表示被分析。骨髓的的树枝状的房间从外部血被孤立,他们的功能被测试。吞噬作用用 FITC 葡聚糖祷告被分析,肽特殊刺激,在多形核白细胞 dI:dC 之上刺激 allogeneic T 房间和 cytokines 的分泌物的能力被测试。结果:骨髓的的树枝状的房间与 HCC 在病人被减少。在 CD80, CD83, CD86 和 HLA 医生表示的差别都没从 HCC 病人和健康控制在天真、刺激的骨髓的的树枝状的房间上被发现。肽 specific T 房间的正常吞噬作用或刺激与一个损害 allo-stimulatory 能力和减少的 IL-12 分泌物相对照被观察。结论:在病人的 mDCs 的损害 IL-12 生产能导致建议指导治疗可以提高的那 IL-12 的天真的 T 房间的一个损害 stimulatory 能力在 HCC 病人的肿瘤 specific 免疫者回答。 | Lars A Ormandy Anatol Frber Tobias Cantz Susanne Petrykowska Heiner Wedemeyer Monique Hrning Frank Lehner Michael P Manns Firouzeh Korangy Tim F Greten | 2006 | World Journal of Gastroenterology2006，12，20： | 12 |
| 2 | 参与式管理解决冲突:遥感和GIS用作瑞典北部驯鹿业土地利用需求信息交流的工具显示文摘在解决复杂的土地管理问题时,对短缺或者有争执的资源进行地理评估有助于不同利益相关者之间沟通认识和增进理解。本文中,我们说明如何使用遥感和GIS收集和汇总瑞典北部驯鹿放牧者和其他土地使用者(林业、采矿业、旅游业等等)的土地使用活动及使用模式的信息。该项目主要基于最终的土地使用者,即驯鹿放牧者们所做的工作,体现了面向土地使用者的新的努力。发展驯鹿业的土地利用规划的基础有以下几个方面:收集并数字化传统的驯鹿栖息地生态学和景观信息;将这些信息与来自野外调查及基于人造卫星观测的植被分类结果整合;绘制其他土地使用者的活动情况图。最终的土地利用规划提供的信息有利于驯鹿放牧者与其他利益相关者之间的磋商,并有助于驯鹿管理实施。该项目可作为一种大众参与和计划编制的模式,从而使本土信息和先进的遥感技术融入一个交互式的过程中。 | Per Sandstrm Tina Granqvist Pahlén Lars Edenius Hans Tφmmervik Olle Hagner Leif Hemberg Hkan Olsson Karin Baer Thomas Stenlund Lars Gran Brandt Mikael Egberth 周立志 程利群 | 2003 | AMBIO-人类环境杂志2003，32，8： | 4 |
| 3 | Role of HSP-90 for increased nNOS-mediated vasodilation in mesenteric arteries in portal hypertension显示文摘AIM:To explore the role of heat shock protein-90 (HSP-90) for nitrergic vasorelaxation in the splanchnic circulation in rats with and without portal hypertension. METHODS: Neuronal nitric oxide synthase (nNOS) and HSP-90 were analyzed by immunofluorescence, western blotting and co-immunoprecipitation in the mesenteric vasculature and isolated nerves of portal-vein-ligated (PVL) rats and sham operated rats. In vitro perfused de-endothelialized mesenteric arterial vasculature was preconstricted with norepinephrine (EC80) and tested for nNOS-mediated vasorelaxation by periarterial nerve stimulation (PNS, 2-12 Hz, 45V) before and after incubation with geldanamycin (specific inhibitor of HSP-90 signalling, 3 μg/mL) or L-NAME (non-specific NOSblocker, 10-4 mol/L). RESULTS: nNOS and HSP-90 expression was significantly increased in mesenteric nerves from PVL as compared to sham rats. Moreover, nNOS and HSP-90 were visualized in mesenteric nerves by immunofluorescence and immunoprecipitation of nNOS co-immunoprecitated HSP-90 in sham and PVL rats. PNS induced a frequencydependent vasorelaxation which was more pronounced in PVL as compared to sham rats. L-NAME and geldanamycin markedly reduced nNOS-mediated vasorelaxation abrogating differences between the study groups. The effect of L-NAME and geldanamycin on nNOS-mediated vasorelaxation was significantly greater in PVL than in sham animals. However, no difference in magnitude of effect between L-NAME and geldanamycin was noted. CONCLUSION: HSP-90 acts as a signalling mediator of nNOS-dependent nerve mediated vascular responses in mesenteric arteries, and the increased nitrergic vasorelaxation observed in portal hypertension is mediated largely by HSP-90. | Lukas Moleda Lars Jurzik Matthias Froh Erwin Gbele Claus Hellerbrand Rainer H Straub Jürgen Schlmerich Reiner Wiest | 2010 | World Journal of Gastroenterology2010，16，15： | 4 |
| 4 | Salpingotomy versus salpingectomy in women with tubal pregnancy (ESEP study): an open-label, multicentre, randomised controlled trial显示文摘 | Femke Mol Norah M van Mello Annika Strandell Karin Strandell Davor Jurkovic Jackie Ross Kurt T Barnhart Tamer M Yalcinkaya Harold R Verhoeve Giuseppe C M Graziosi Carolien A M Koks Ingmar Klinte Lars Hogstr?m Ineke C A H Janssen Harry Kragt Annemieke Hoek | 2014 | The Lancet2014，，： | 2 |
| 5 | Stent Thrombosis With Ticagrelor Versus Clopidogrel in Patients With Acute Coronary Syndromes: An Analysis From the Prospective, Randomized PLATO Trial显示文摘 | P. Gabriel Steg Robert A. Harrington H?kan Emanuelsson Hugo A. Katus Kenneth W. Mahaffey Bernhard Meier Robert F. Storey Daniel M. Wojdyla Basil S. Lewis Gerald Maurer Lars Wallentin Stefan K. James | 2013 | Circulation2013，，10： | 2 |
| 6 | The boundary problems of physical geodesy显示文摘 | Lars H?rmander | 1976 | Archive for Rational Mechanics and Analysis1976，，1： | 2 |
| 7 | The polycomb-group protein MEDEA regulates seed development by controlling experssion of the MADS-box gene PHERES1显示文摘 | CLAUDIA K LARS H CHARLES S | 2003 | Genes and Development2003，17，： | 1 |
| 8 | Analysis of heavy metals in road-deposited sediments 显示文摘 | Lars H Ashantha G Godwin A A | 2006 | Analytica Chimica Acta2006，571，： | 1 |
| 9 | L 2 estimates and existence theorems for the $$\bar \partial $$ operator显示文摘 | Lars H?rmander | 1965 | Acta Mathematica1965，，1： | 1 |
| 10 | Leydig cell death in rats exposed to bismuth subnitrate显示文摘 | Lars H P Meredin S Erik E | 2003 | Journal of Applied Toxicology2003，23，4： | 1 |
| 11 | Strength criteria in semi-analytical, large deflection analysis of stiffened plates in local and global bending显示文摘 | LARS B JOSTEIN H | 2008 | Thin-Walled Structures2008，46，12： | 1 |
| 12 | DICTRA, a tool for simulation of diffusional transformations in alloys显示文摘 | Annika Borgenstam Lars H?glund John ?gren Anders Engstr?m | 2000 | Journal of Phase Equilibria2000，，3： | 1 |
| 13 | Mercury in fish in Swedish lakes — Linkages to domestic and European sources of emission显示文摘 | Lars H?kanson Tord Andersson ?ke Nilsson | 1990 | Water Air and Soil Pollution (-)1990，，1： | 1 |
| 14 | Chromosomal Aberrations in Lymphoeytes Predict Human Cancer Independently of Exposure to Carcinogens显示文摘 | Stefano B Lars H Alicia H | 2000 | Cancer Res2000，60，： | 1 |
| 15 | World Health Organization (WHO) and International Society of Hypertension (ISH) risk prediction charts: assessment of cardiovascular risk for prevention and control of cardiovascular disease in low and middle-income countries显示文摘 | Shanthi M Lars H L Giuseppe M | 2007 | Journal of hypertension2007，25，8： | 1 |
| 16 | An ecological risk index for aquatic pollution control: A sediment ecological approach 显示文摘 | Lars H | 1980 | Water Research1980，14，： | 1 |
| 17 | The spectral function of an elliptic operator显示文摘 | Lars H?rmander | 1968 | Acta Mathematica1968，，1： | 1 |
| 18 | A comparison of litterfall andelement fluxes in even aged Norway spruce, sitka spruceand beech stands in Denmark显示文摘 | LARS B P J0RGEN B H | 1999 | Forest Ecology andManagement1999，114，1： | 1 |
| 19 | The Value Relevance of Environmen- tal Performance 显示文摘 | LARS H HENRIK N SIV N | 2005 | European Accounting Review2005，14，1： | 1 |
| 20 | Dynamic coupling of computational fluid dynamics and thermodynamics software: applied on a top blown converter显示文摘 | Mikael ERSSON Lars H?GLUND Anders TILLIANDER | 2008 | ISIJ International2008，48，2： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员