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| 1 | 长期食用含糖和人工甜味剂的饮料与美国成年人死亡风险的关系显示文摘摄入含糖饮料(sugar-sweetened beverages,SSB)或含人工甜味剂饮料(artificially sweetened beverages,ASB)是否与死亡风险相关,这关乎公共卫生利益。研究者分析了卫生专业人员随访研究(1986-2014年)中男性37 716人和护士健康研究(1980-2014年)中女性80 647人(基线无慢性病)的SSB和ASB的消费与总死亡率和病因特异性死亡率之间的关系。应用Cox比例风险回归估计风险比和95%CI。结果显示,在随访3415564人年期间,研究者记录了36436例死亡,其中心血管病死亡7896例,癌症死亡12380例。 | 刘青(译) 叶鹏(摘、审校) Malik VS Li Y Pan A De Koning L Schernhammer E Willett WC Hu FB | 2019 | 中华高血压杂志2019，27，5： | 9 |
| 2 | Gender influence on defecographic abnormalities in patients with posterior pelvic floor disorders显示文摘AIM:To compare defecographic abnormalities in symptomatic men and women and to analyze differences between men and age-and symptom-matched women.METHODS:Sixty-six men(mean age:55.4 years,range:20-81 years) who complained of constipation and/or fecal incontinence and/or pelvic pain underwent defecography after intake of a barium meal.Radiographs were analyzed for the diagnosis of rectocele,enterocele,intussusception and perineal descent.They were compared with age-and symptom-matched women(n = 198) who underwent defecography during the same period.RESULTS:Normal defecography was observed in 22.7% of men vs 5.5% of women(P < 0.001).Defecography in men compared with women showed 4.5%vs 44.4%(P < 0.001) rectocele,and 10.6% vs 29.8%(P < 0.001) enterocele,respectively.No difference was observed for the diagnosis of intussusception(57.6% vs 44.9%).Perineal descent at rest was more frequent in women(P < 0.005).CONCLUSION:For the same complaint,diagnosis of defecographic abnormalities was different in men than in women:rectocele,enterocele and perineal descent at rest were observed less frequently in men than in women. | Céline Savoye-Collet Guillaume Savoye Edith Koning Anne-Marie Leroi Jean-Nicolas Dacher | 2010 | World Journal of Gastroenterology2010，16，4： | 8 |
| 3 | Magnetic resonance imaging may predict deep remission in patients with perianal fistulizing Crohn's disease显示文摘AIM To evaluate the imaging course of Crohn's disease(CD) patients with perianal fistulas on long-term maintenance anti-tumor necrosis factor(TNF)-α therapy and identify predictors of deep remission.METHODS All patients with perianal CD treated with anti-TNF-α therapy at our tertiary care center were evaluated by magnetic resonance imaging(MRI) and clinical assessment. Two MR examinations were performed: at initiation of anti-TNF-α treatment and then at least 2 years after. Clinical assessment(remission, response and non-response) was based on Present's criteria. Rectoscopic patterns, MRI Van Assche score, and MRI fistula activity signs(T2 signal and contrast enhancement) were collected for the two MR examinations. Fistula healing was defined as the absence of T2 hyperintensity and contrast enhancement on MRI. Deep remission was defined as the association of both clinical remission, absence of anal canal ulcers and healing on MRI. Characteristics and imaging patterns of patients with and without deep remission were compared by univariate and multivariate analyses.RESULTS Forty-nine consecutive patients(31 females and 18 males) were included. They ranged in age from 14-70 years(mean, 33 years). MRI and clinical assessment were performed after a mean period of exposure to anti-TNF-α therapy of 40 ± 3.7 mo. Clinical remission, response and non-response were observed in 53.1%, 20.4%, and 26.5% of patients, respectively. Deep remission was observed in 32.7% of patients. Among the 26 patients in clinical remission, 10 had persisting inflammation of fistulas on MRI(T2 hyperintensity, n = 7; contrast enhancement, n = 10). Univariate analysis showed that deep remission was associated with the absence of rectal involvement and the absence of switch of anti-TNF-α treatment or surgery requirement. Multivariate analysis demonstrated that only the absence of rectal involvement(OR = 4.6; 95%CI: 1.03-20.5) was associated with deep remission.CONCLUSION Deep remission is achieved in approximately one third of patients on maintenance anti-TNF-α therapy. Absence of rectal involvement is predictive of deep remission. | Lucie Thomassin Laura Armengol-Debeir Cloé Charpentier Valerie Bridoux Edith Koning Guillaume Savoye Céline Savoye-Collet | 2017 | World Journal of Gastroenterology2017，23，23： | 5 |
| 4 | CT筛查降低肺癌死亡率的随机试验显示文摘目前在曾经和现在吸烟的男性中,基于容积的低剂量计算机断层扫描(CT)筛查能否降低肺癌死亡率的随机试验证据有限。2020年初新英格兰医学杂志报道了一项来自欧洲的CT筛查对降低肺癌死亡率的临床试验结果。该研究招募了50~74岁的13195名男性(主要分析)和2594名女性(亚组分析),并将其随机分配至不筛查对照组和干预组,后者分别在基线、第1年、第3年和第5.5年进行CT筛查。通过荷兰和比利时国家登记处获得癌症诊断、死亡日期和死因。 | 王红(译) 唐威(译) 石菊芳(译) De Koning HJ Van der Aalst CM De Jong PA | 2020 | 中华预防医学杂志2020，54，7： | 5 |
| 5 | Muc2-Deficient Mice Spontaneously Develop Colitis, Indicating That MUC2 Is Critical for Colonic Protection显示文摘 | Maria Van der Sluis Barbara A.E. De Koning Adrianus C.J.M. De Bruijn Anna Velcich Jules P.P. Meijerink Johannes B. Van Goudoever Hans A. Büller Jan Dekker Isabelle Van Seuningen Ingrid B. Renes Alexandra W.C. Einerhand | 2006 | Gastroenterology2006，，1： | 3 |
| 6 | RIPL – Reference Input Parameter Library for Calculation of Nuclear Reactions and Nuclear Data Evaluations显示文摘 | R. Capote M. Herman P. Oblo?insky P.G. Young S. Goriely T. Belgya A.V. Ignatyuk A.J. Koning S. Hilaire V.A. Plujko M. Avrigeanu O. Bersillon M.B. Chadwick T. Fukahori Zhigang Ge Yinlu Han S. Kailas J. Kopecky V.M. Maslov G. Reffo M. Sin E.Sh. Soukhovitski | 2009 | Nuclear Data Sheets2009，，12： | 2 |
| 7 | Stability of roadways in coalmines alias rock mechanics in practice显示文摘This paper describes the procedures for design of supports and stabilization measures in the roadways.The procedures are based on the system developed in Ostrava-Karvina coal basin in Czech Republic.The calculation of load bearing capacity of roadway supports contains the period of roadway construction and mining in the vicinities,based on the size of the natural rock arch.The loading of supports during mining comes from a stress wave in the rock mass in the forefront of coalface and the caving area of mined-out panel.The input data for the calculation method are deduced according to in-situ measurements of convergence and displacement in the roadways. | Richard nupárek Petr Koneny | 2010 | Journal of Rock Mechanics and Geotechnical Engineering2010，2，3： | 2 |
| 8 | Community knowledge,attitudes and practices related to schistosomiasis and associated healthcare-seeking behaviours in northern Côte d’Ivoire and southern Mauritania显示文摘Background:Among parasitic infections,schistosomiasis ranks second after malaria in terms of worldwide morbidity.Despite efforts to contain transmission,more than 230 million people are infected,of which 85%live in Sub-Saharan Africa.While the epidemiologic characteristics of schistosomiasis have been extensively studied across endemic settings,social factors have been paid less attention.The current study assesses community knowledge of schistosomiasis causes,transmission,signs,symptoms and prevention,as well as healthcare-seeking behaviours in two West African settings,with the aim of strengthening schistosomiasis control interventions.Methods:From August 2014 to June 2015,we conducted two cross-sectional surveys in Korhogo,Cote d’Ivoire and Kaedi,Mauritania.We applied a questionnaire to collect quantitative data at the household level in Korhogo(n=1456)and Kaedi(n=1453).Focus group discussions(Korhogo:n=32,Kaedi:n=32)and participatory photography(photovoice)(Korhogo:n=16,Kaedi:n=16)were conducted within the communities to gather qualitative data.In addition,semi-structured interviews were used to discuss with key informants from control programmes,nongovernmental organizations and health districts(Korhogo:n=8,Kaedi:n=7).Results:The study demonstrated that schistosomiasis is not well known by the communities;64.1%claimed to know the causes of the disease,but the reality is different.This knowledge is more from cultural than biomedical source.It was observed that social construction of the disease is different from the biomedical definition.In Korhogo,schistosomiasis was often associated with several other diseases,notably stomach ulcer and gonorrhoea.The populations believe that schistosomiasis is caused by exposure to goat or dog urine in the environment.In Kaedi,schistosomiasis is considered as a disease transmitted by environmenal elements such as sunshine and dirty water.In both settings,the care-seeking pathways were found to be strongly influenced by local customs and self-medication acquired from the informal sector.Conclusions:This study revealed that knowledge about the aetiology,transmission,symptoms,prevention and treatment of schistosomiasis among the populations in Korhogo and Kaedi is based on their local culture.Deep-rooted habits could therefore pose a significant obstacle to the elimination of schistosomiasis. | Amoin Jeanne d’Arc Koffi Mohamed Doumbia Gilbert Fokou Moussa Keita Brama Kone N’doumy Noel Abe | 2018 | Infectious Diseases of Poverty2018，7，1： | 2 |
| 9 | Oxidation of 2,4,6-trinitrotoluene in the presence of different iron-bearing minerals at neutral pH显示文摘 | Roger Matta Khalil Hanna Tiangoua Kone Serge Chiron | 2008 | Chemical Engineering Journal2008，，3： | 2 |
| 10 | 一种从冠状动脉X线造影生成最佳投照角度的新方法显示文摘虽然冠状动脉介入治疗是治疗冠心病最主要的方法之一,但其一定比例的再狭窄率以及由再狭窄和支架内血栓所导致的高病死率和高致残率仍限制着该方法的进一步应用。 | 涂圣贤 魏向龙 宋旭东 郝培远 黄铮 Koning Gerhard Reiber Johan HC | 2011 | 中华放射学杂志2011，45，2： | 2 |
| 11 | Protein - protein interactions controlling nitric oxide synthases显示文摘 | Kone BC | 2000 | Acta Physiol Scand2000，168，1： | 2 |
| 12 | Contribution of Promiscuous Soybean (Glycine max L.) to Upland Rice-based Cropping Systems in West Africa显示文摘 | S. Oikeh P. Houngnandan A. Robert A. Niang A. Toure B. Kone | 2010 | Journal of Agricultural Science and Technology2010，4，1： | 2 |
| 13 | Wastewater reuse in Europe显示文摘 | D. Bixio C. Thoeye J. De Koning D. Joksimovic D. Savic T. Wintgens T. Melin | 2006 | Desalination2006，，1： | 2 |
| 14 | POST-INJURY MULTIPLE ORGAN FAILURE: THE ROLE OF THE GUT显示文摘 | Heitham T. Hassoun Bruce C. Kone David W. Mercer Frank G. Moody Norman W. Weisbrodt Frederick A. Moore | 2001 | Shock2001，，1： | 2 |
| 15 | Expression and prognostic significance of thymidylate synthase (TS) in pancreatic head and periampullary cancer显示文摘 | J.A. van der Zee C.H.J. van Eijck W.C.J. Hop H. van Dekken B.M. Dicheva A.L.B. Seynhaeve G.A. Koning A.M.M. Eggermont T.L.M. ten Hagen | 2012 | European Journal of Surgical Oncology2012，，11： | 2 |
| 16 | 责任金融:将原则付诸实践显示文摘小额金融具有双重底线的特征,近年来爆发的信贷危机凸显双重底线之间存在的矛盾冲突。基于此,有必要对双重底线进行重新平衡,而出路就是实施责任金融战略。文章首先界定了责任金融的内涵;随后从行业自我监管、政府监管、消费者能力提高三个方面探讨了责任金融对客户保护的三个战略;最后结合实践发展现状提出了推动责任金融发展的建议。 | Mekee,Lahaye Koning | 2013 | 科学决策2013，，11： | 2 |
| 17 | The Jupiter study, CRP screening, and aggressive statin therapy-implications for the primary prevention of cardiovascular disease显示文摘 | Richard Kones | 2009 | Ther Adv Cardiovasc Dis2009，3，4： | 1 |
| 18 | Molecular biology of natriuretic peptide and nitric oxide syn - thases 显示文摘 | Kone BC | 2001 | Cardiovasc Res2001，51，3： | 1 |
| 19 | A new potent and selective histamine H3 receptor agonist immepip (vuf4708)显示文摘 | Koning JP Jansen FP | 1994 | J Med Chem1994，37，3： | 1 |
| 20 | Determination of optimal pacing strategy in track cycling with an energy flow model显示文摘 | DE KONING J J BOBBERT M F FOSTER C | 1992 | J Sci Med Sport1992，2，3： | 1 |
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