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306篇 您的检索式:作者名="Kaye D M"
    题名 作者 年代 出处 被引量
1Regression of cirrhosis during treatment with tenofovir disoproxil fumarate for chronic hepatitis B: a 5-year open-label follow-up study显示文摘Patrick Marcellin Edward Gane Maria Buti Nezam Afdhal William Sievert Ira M Jacobson Mary Kay Washington George Germanidis John F Flaherty Raul Aguilar Schall Jeffrey D Bornstein Kathryn M Kitrinos G Mani Subramanian John G McHutchison E Jenny Heathcote 2012The Lancet2012,,:14
2高纤维膳食和补充乙酸盐改变肠道菌群,预防醋酸脱氧皮质酮-盐型高血压小鼠高血压和心力衰竭的发展显示文摘水果和蔬菜的膳食摄入与高血压的发生率较低有关,但所涉及的机制尚未阐明。该研究评估了高纤维膳食和短链脂肪酸(short-chain fatty acid,SCFA)(乙酸盐)对肠道微生物群和预防心血管病的影响。方法:用盐皮质激素诱发小鼠高血压模型,观测正常喂食组、高纤维喂食组和补充乙酸盐组的肠道微生物、心脏结构/功能和血压水平。刘莉 叶鹏 Marques FZ Nelson EM Chu PY Horlock D Fiedler A Ziemann M Tan JK Kuruppu S Rajapakse NW El-Osta A Mackay CR Kaye DM 2016中华高血压杂志2016,24,12:8
3Identification of pathologic features associated with “ulcerative colitis-like” Crohn's disease显示文摘AIM: To identify pathologic features associated with this 'ulcerative colitis(UC)-like' subgroup of Crohn's disease(CD).METHODS: Seventeen subjects diagnosed as having UC who underwent proctocolectomy(RPC) from 2003-2007 and subsequently developed CD of the ileal pouch were identified. UC was diagnosed based on preoperative clinical, endoscopic, and pathologic studies. Eighteen patients who underwent RPC for UC within the same time period without subsequently developing CD were randomly selected and used as controls. Pathology reports and histological slides were reviewed for a wide range of gross and microscopic pathological features, as well as extent of disease. The demographics, gross description and histopathology of the resection specimens were reviewed and compared between the two groups. RESULTS: Patients with 'UC-like' CD were on average 13 years younger than those with 'true' UC(P < 0.01). More severe disease in the proximal involved region and active ileitis with/without architectural distortion were observed in 6 of 17(35%) and 7 of 17(41%) 'UC-like' CD cases, respectively, but in none of the 'true' UC cases(P < 0.05). Active appendicitis occurred in 8 of 16(50%) 'UC-like' CD cases but in only two(11%) 'true' UC cases(P < 0.05). Conspicuous lamina propria neutrophils were more specific for 'UClike' CD(76% vs 22%, P < 0.05). In addition, prominent lymphoid aggregates tended to be more common in 'UC-like' CD(P = 0.07). The 'true' UC group contained a greater number of cases with severe activity(78% vs 47%). Therefore, the features more commonly seen in 'UC-like' CD were not due to a more severe disease process. Crohn's granulomas and transmural inflammation in non-ulcerated areas were absent in both groups.CONCLUSION: More severe disease in the proximal involved region, terminal ileum involvement, active appendicitis, and prominent lamina propria neutrophils may be morphological factors associated with 'UC-like' CD.Samuel D James Paul E Wise Tania Zuluaga-Toro David A Schwartz M Kay Washington Chanjuan Shi 2014World Journal of Gastroenterology2014,20,36:4
4Epidermal growth factor receptor inhibits colitis-associated cancer in mice显示文摘Dubé Philip E Yan Fang Punit Shivesh Girish Nandini McElroy Steven J Washington M Kay Polk D Brent 2012EN2012,,8:2
5Transgenic mice expressing human Immuno-Deficiency Virus Type 1 in immune cells develop a severe AIDS-like disease显示文摘Hanna Z Kay D G Cool M 1998J Virol1998,72,1:1
6Adrenec nervous systemin heat failure 显示文摘Esler M Kaye D Lambert G 1997Am J Cardid1997,80,:1
7Measurement of sympathetic nervous system activity in heart failure:the role of norepinephrine kinetics显示文摘Esler M Kaye D 2000Heart Fail Rev2000,5,1:1
8Starch synthesis in the cereal endosperm显示文摘MARTHA G J KAY D ALAN M M 2003Current Opinion in Plant Biology2003,6,:1
9Meta - analysis oftympanostomy tube sequelae 显示文摘KAY D J NELSON M ROSENFELD R M 2001Otolaryngol Head Neck Surg2001,124,4:1
10A comparison of three approaches to spatial generalization of rainfall-runoff models显示文摘Kay A L Jones D A Crooks S M 2006Hydrology Processes2006,20,:1
11The effects of interhelical electrostatic repulsions between glutamic acid residues in controlling the dimerization and stability of two-stranded alpha-helical coiled-coils显示文摘Kohn W D Monera O D Kay C M 1995J Biol Chem1995,270,25:1
12Laboratory diagnosis and surveillance of human respiratory viruses by PCR in Victoria, Australia, 2002-2003 显示文摘Druce J Tran T Kelly H Kaye M Chibo D Kostecki R Amiri A Catton M Birch C 2005J Med Virol2005,75,1:1
13Antiadrenergic effect of chronic amiodarone 显示文摘Kaye D M Dart A M Jennings G L 1999J Am Coll Cardiol1999,33,6:1
14Analysis and compensa- tion of bandpass nonlinearities for communications显示文摘KAYE A GEORGE D ERIC M 1972Com- munications IEEE Transactions on1972,20,5:1
15Molecular and phenotypic characterization of Als1 and Als2 mutations conferring tolerance to acetolactate synthase herbicides in soybean显示文摘Kay L Walter Stephen D Strachan Nancy M Ferry Henrik H Albert Linda A Castle Scott A Sebastian 2014Pest. Manag. Sci2014,,12:1
16Evaluating the operational utility of a bacteroidales quantitative PCR- based MST approach in determining the source of faecal indicator organisms at a UK bathing water 显示文摘Stapleton C M Kay D Wyer M D 2009Water Re- search2009,43,19:1
17The role of cyclooxygenase in the feline pulmonary vascular bed 显示文摘Kaye A D Hoover J M Kaye A J 2007Am J Therapeutics2007,14,:1
18Adrenergic nervous system in heart failure显示文摘 Kaye D Lambert G 1997Am J Cardio11997,80,:1
19The permanence of the visual recovery that follows reverse occlusion of monocularly deprived kittens显示文摘MITCHELL D E MURPHY K M KAYE M G 1984Invest Ophthalmol Vis Sci1984,25,8:1
20Therapeutic application of RNAi is mRNA targeting finally ready for prime time?显示文摘GRIMM D KAY M A 2007J Clin Invest2007,117,12:1
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