|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Arsenic speciation in fish from Greek coastal areas显示文摘Arsenic speciation analysis was conducted on fish samples(sardine and anchovy) collected from six areas along the Greek coastline, i.e. Artemisium Straits, Thermaikos Gulf, Amvrakikos Gulf,Strymonian Gulf, Thracian Sea, and Elefsina Gulf. Total arsenic levels ranging from 11.8 to62.6 mg As/kg dry weight were determined. Arsenobetaine, a non-toxic form of arsenic, was found to be the main arsenic species, present at 8.6 to 58.8 mg As/kg dry weight, accounting for67–95% of the total arsenic. Also detected in all fish samples was dimethylarsinic acid, although at considerably lower concentrations, ranging from 0.072–0.956 mg As/kg dry weight.Monomethylarsonic acid was detected at low levels in all anchovy samples, and only in sardines from one area. Finally, inorganic arsenic in the form of arsenate was detected only in fish at one area, indicating the possible effect of an environmental parameter on its presence at detectable amounts. Statistical analysis revealed the environmental variables, such as salinity,total organic carbon and nitrogen, ammonium, phosphate, total phosphorus, dissolved oxygen and pressure index, are potentially correlated to As species concentrations. Furthermore, based on factor analysis, the biological parameters, such as fish weight, lipids, protein and ash content,that are correlated to As species concentrations of fish were also identified. The interrelationship of arsenobetaine and dimethylarsinic acid concentrations within each fish species was evaluated. | Ioanna Kalantzi Kyriaki Mylona Katerina Sofoulaki Manolis Tsapakis Spiros A.Pergantis | 2017 | Journal of Environmental Sciences2017，29，6： | 11 |
| 2 | Small bowel ulcerative lesions are common in elderly NSAIDs users with peptic ulcer bleeding显示文摘AIM: To determine the frequency of small bowel ulcerative lesions in patients with peptic ulcer and define the significance of those lesions. METHODS: In our prospective study, 60 consecutive elderly patients with upper gastrointestinal bleeding from a peptic ulceration(cases) and 60 matched patients with a non-bleeding peptic ulcer(controls) underwent small bowel capsule endoscopy, after a negative colonoscopy(compulsory in our institution). Controls were evaluated for non-bleeding indications. Known or suspected chronic inflammatory conditions and medication that could harm the gut were excluded. During capsule endoscopy, small bowel ulcerative lesions were counted thoroughly and classified according to Graham classification. Other small bowellesions were also recorded. Peptic ulcer bleeding was controlled endoscopically, when adequate, proton pump inhibitors were started in both cases and controls, and Helicobacter pylori eradicated whenever present. Both cases and controls were followed up for a year. In case of bleeding recurrence upper gastrointestinal endoscopy was repeated and whenever it remained unexplained it was followed by repeat colonoscopy and capsule endoscopy.RESULTS: Forty(67%) cases and 18(30%) controls presented small bowel erosions(P = 0.0001), while 22(37%) cases and 4(8%) controls presented small bowel ulcers(P < 0.0001). Among non-steroidal antiinflammatory drug(NSAID) consumers, 39(95%) cases and 17(33%) controls presented small bowel erosions(P < 0.0001), while 22(55%) cases and 4(10%) controls presented small bowel ulcers(P < 0.0001). Small bowel ulcerative lesions were infrequent among patients not consuming NSAIDs. Mean entry hemoglobin was 9.3(SD = 1.4) g/d L in cases with small bowel ulcerative lesions and 10.5(SD = 1.3) g/dL in those without(P = 0.002). Cases with small bowel ulcers necessitate more units of packed red blood cells. During their hospitalization, 6(27%) cases with small bowel ulcers presented bleeding recurrence most possibly attributed to small bowel ulcers, nevertheless 30-d mortality was zero. Presence of chronic obstructive lung disease and diabetes was related with unexplained recurrence of hemorrhage in logistic regression analysis, while absence of small bowel ulcers was protective(relative risk 0.13, P = 0.05).CONCLUSION: Among NSAID consumers, more bleeders than non-bleeders with peptic ulcers present small bowel ulcers; lesions related to more severe bleeding and unexplained episodes of bleeding recurrence. | Panagiotis Tsibouris Chissostomos Kalantzis Periklis Apostolopoulos Antonios Zalonis Peter Edward Thomas Isaacs Mark Hendrickse Georgios Alexandrakis | 2014 | World Journal of Gastrointestinal Endoscopy2014，6，12： | 6 |
| 3 | Capsule endoscopy retention as a helpful tool in the management of a young patient with suspected small-bowel disease显示文摘Capsule endoscopy is an easy and painless procedure permitting visualization of the entire small-bowel during its normal peristalsis. However, important problems exist concerning capsule retention in patients at risk of small bowel obstruction. The present report describes a young patient who had recurrent episodes of overt gastrointestinal bleeding of obscure origin, 18 years after small bowel resection in infancy for ileal atresia. Capsule endoscopy was performed, resulting in capsule retention in the distal small bowel. However, this event contributed to patient management by clearly identifying the site of obstruction and can be used to guide surgical intervention, where an anastomotic ulcer is identified. | Chryssostomos Kalantzis Periklis Apostolopoulos Panagiota Mavrogiannis Dimitrios Theodorou Xenophon Papaharalampous Ioannis Bramis Nikolaos Kalantzis | 2007 | World Journal of Gastroenterology2007，13，8： | 5 |
| 4 | Clinicopathological differences and correlations between right and left colon cancer显示文摘BACKGROUND The differences in histopathology and molecular biology between right colon cancer(RCC)and left colon cancer(LCC)were first reported in the literature by Bufill in 1990.Since then,a large number of studies have confirmed their differences in epidemiology,clinical presentation,comorbidities and biological behaviours,which may be related to the difference in prognosis and overall survival(OS)between the two groups.AIM To investigate statistically significant differences between Greek patients with LCC and RCC.METHODS The present observational study included 144 patients diagnosed with colon cancer of any stage who received chemotherapy in a Greek tertiary oncology hospital during a 2.5-year period.Clinical information,comorbidities,histopathologic characteristics and molecular biomarkers were collected from the patients’medical records retrospectively,while administered chemotherapy regimens,targeted agents,progression-free survival(PFS)periods with first-and second-line chemotherapy and OS were recorded retroactively and prospectively.Data analysis was performed with the SPSS statistical package.RESULTS Eighty-six males and 58 females participated in the study.One hundred(69.4%)patients had a primary lesion in the left colon,and 44(30.6%)patients had a primary lesion in the right colon.Patients with RCC were more likely to display anaemia than patients with LCC[odds ratio(OR)=3.09],while LCC patients were more likely to develop rectal bleeding(OR=3.37)and a feeling of incomplete evacuation(OR=2.78)than RCC patients.Considering comorbidities,RCC patients were more likely to suffer from diabetes(OR=3.31)and coronary artery disease(P=0.056)than LCC patients.The mucinous differentiation rate was higher in the right-sided group than in the left-sided group(OR=4.49),as was the number of infiltrated lymph nodes(P=0.039),while the percentage of high-grade differentiation was higher in the group of patients with left-sided colon cancer than in RCC patients(OR=2.78).RAS wild-type patients who received anti-epidermal growth factor receptor(EGFR):Treatment experienced greater benefit(PFS:16.5 mo)than those who received anti-vascular endothelial growth factor treatment(PFS:13.7 mo)(P=0.05),while among RAS wild-type patients who received anti-EGFR treatment,LCC patients experienced greater benefit(PFS:15.8 mo)than the RCC subgroup(PFS:5.5 mo)in the first-line chemotherapy setting(P=0.034).BRAF-mutant patients had shorter PFS(9.3 mo)than BRAF wild-type patients(14.5 mo)(P=0.033).RCC patients showed a shorter tumour recurrence period(7.7 mo)than those with LCC(14.5 mo)(P<0.001),as well as shorter(OS)(58.4 mo for RCC patients;82.4 mo for LCC patients)(P=0.018).CONCLUSION RCC patients present more comorbidities,worse histological and molecular characteristics and a consequently higher probability of tumour recurrence,poor response to targeted therapy and shorter OS than LCC patients. | Ioannis Kalantzis Afroditi Nonni Kitty Pavlakis Eumorphia-Maria Delicha Konstantinos Miltiadou Christos Kosmas Nikolaos Ziras Konstantinos Gkoumas Harikleia Gakiopoulou | 2020 | World Journal of Clinical Cases2020，8，8： | 4 |
| 5 | Ibutilide and novel indexes of ventricular repolarization in persistent atrial fibrillation patients显示文摘AIM: To examine the effect of ibutilide on novel indexes of repolarization in patients with persistent atrial fibrillation (AF). METHODS: We studied consecutive patients scheduled for elective electrical cardioversion. Intravenous ibutilide (1+1mg) was administered before the electrical cardioversion while close electrocardiographic (ECG) monitoring was performed. ECG indexes such as corrected QT interval (QTc), the interval from the peak until the end of T wave (Tpe), and the Tpe/QT ratio were measured before ibutilide infusion and 10 min after the end of infusion. RESULTS: The final study population consisted of 20 patients (mean age: 67.1±9.9 years, 10 men). Six patients were cardioverted pharmacologically and did not proceed to electrical cardioversion. Two patientsdeveloped short non-sustained episodes of torsades de pointes ventricular tachycardia. All but one of the aforementioned ECG indexes increased significantly after ibutilide administration. In specific, the QTc interval increased from 442 ± 29 to 471 ± 37 ms (P=0.037), the Tpe interval in precordial leads from 96 ms (range 80-108 ms) to 101 ms (range 91-119 ms) (P=0.021), the Tpe interval in lead Ⅱ from 79 ms (range 70-88 ms) to 100 ms (range 87-104 ms) (P<0.001), the Tpe/QT ratio in precordial leads from 0.23 ms (range 0.18-0.26 ms) to 0.26 ms (range 0.23-0.28 ms) (P=0.028), and the Tpe interval dispersion from 25 ms (range 23-30 ms) to 35 ms (range 27-39 ms) (P=0.012). However, the Tpe/QT ratio in lead II did not change significantly. CONCLUSION: Ibutilide increases the duration and dispersion of ventricular repolarization. The prognostic value of Tpe and Tpe/QT in the setting of drug-induced proarrhythmia needs further study. | Panagiotis Korantzopoulos Konstantinos P Letsas Anna Kotsia Giannis Baltogiannis Kallirroi Kalantzi Konstantinos Kyrlas John A Goudevenos | 2013 | World Journal of Cardiology2013，5，7： | 3 |
| 6 | Colon capsule endoscopy is feasible to perform after incomplete colonoscopy and guides further workup in clinical practice显示文摘 | Konstantinos Triantafyllou Nikos Viazis Panagiotis Tsibouris Georgios Zacharakis Chryssostomos Kalantzis Demetrios G. Karamanolis Spiros D. Ladas | 2014 | Gastrointestinal Endoscopy2014，，2： | 3 |
| 7 | Evaluation of capsule endoscopy in active, mild-to-moderate, overt, obscure GI bleeding <ce:link locator='fx1'/>显示文摘 | Periklis Apostolopoulos Christos Liatsos Ian M. Gralnek Chrissostomos Kalantzis Eleftheria Giannakoulopoulou Georgios Alexandrakis Panagiotis Tsibouris Evagelos Kalafatis Nikolaos Kalantzis | 2007 | Gastrointestinal Endoscopy2007，，6： | 3 |
| 8 | Validation of the Capsule Endoscopy Crohn’s Disease Activity Index (CECDAI or Niv score): a multicenter prospective study显示文摘 | Y. Niv S. Ilani Z. Levi M. Hershkowitz E. Niv Z. Fireman S. O’Donnel C. O’Morain R. Eliakim E. Scapa N. Kalantzis C. Kalantzis P. Apostolopoulos E. Gal | 2012 | Endoscopy2012，，01： | 2 |
| 9 | Management of esophageal foreign bodies: a retrospective review of 400 cases显示文摘 | Kalliopi Athanassiadi M. Gerazounis E. Metaxas Nikolitsa Kalantzi | 2002 | European Journal of Cardio-Thoracic Surgery2002，，4： | 2 |
| 10 | Distribution of polybrominated diphenyl ethers (PBDEs) and other persistent organic pollutants in human serum from Greece显示文摘 | Olga I. Kalantzi Tinne Geens Adrian Covaci Panayiotis A. Siskos | 2010 | Environment International2010，，2： | 1 |
| 11 | PillCam Colon capsule endoscopy does not always complement incomplete colonoscopy 显示文摘 | Triantafyllou K Tsibouris P Kalantzis C | 2009 | Gastrointest Endosc2009，69，31： | 1 |
| 12 | Recent ad- vances in oral pulsatile drug delivery 显示文摘 | KALANTZI LE KARAVAS E KOUTRIS EX | 2009 | Recent Pat Drug Deliv Formul2009，3，1： | 1 |
| 13 | Real-time cine MRI of ventricular septal motion:a novel approach to assess ventricular coupling显示文摘 | Francone M Dymarkowski S Kalantzi M | 2005 | J Magn Reson Imaging2005，21，3： | 1 |
| 14 | Insulin-like growth factor-I and IGF-1 receptors in diabetic patients with neuropathy显示文摘 | Migdalis IN Kalogeropoulou K Kalantzis L | 1995 | Diabet Med1995，12，9： | 1 |
| 15 | Helicobacter pylori cagA triggers expression of the bactericidal lectin REG3γ via gastric STAT3 Activation显示文摘 | Lee KS Kalantzis A Jackson CB | 2012 | PLoS One2012，7，30： | 1 |
| 16 | Capsule en- doscopy: the cumulative experience from its use in 193 patients with suspected small bowel disease 显示文摘 | Kalantzis N Papanikolaou IS Giannakoulopouloue | 2005 | Hepatogastroenterology2005，52，62： | 1 |
| 17 | Designs for learning显示文摘 | Kalantzis M&Cope B | 2004 | E-Learning2004，，1： | 1 |
| 18 | Fidelity of dose delivery at high dose rate of volumetric modulated arc therapy in a truebeam linac with flattening filter free beams显示文摘 | Kalantzis G Qian J Han B | 2012 | J Med Phys2012，37，4： | 1 |
| 19 | Different levels of polybrominated diphenyl ethers (PBDEs) and chlorinated compounds in breast milk from Two UK Regions显示文摘 | KALANTZI I MARTIN F L THOMAS G O | 2004 | Environmental Health Perspectives2004，112，10： | 1 |
| 20 | Heavy metals, trace elements and sediment geochemistry at four Mediterranean fish farms显示文摘 | I. Kalantzi T.M. Shimmield S.A. Pergantis N. Papageorgiou K.D. Black I. Karakassis | 2013 | Science of the Total Environment2013，，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员