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| 1 | CRP and fibrinogen imply clinical outcome of patients with Type-2 diabetes and coronary artery disease显示文摘 | Marijan Bosevski Golubinka Bosevska Lily Stojanovska Vasso Apostolopoulos~ | 2017 | Acta Biochimica et Biophysica Sinica2017，49，3： | 8 |
| 2 | Small bowel ulcerative lesions are common in elderly NSAIDs users with peptic ulcer bleeding显示文摘AIM: To determine the frequency of small bowel ulcerative lesions in patients with peptic ulcer and define the significance of those lesions. METHODS: In our prospective study, 60 consecutive elderly patients with upper gastrointestinal bleeding from a peptic ulceration(cases) and 60 matched patients with a non-bleeding peptic ulcer(controls) underwent small bowel capsule endoscopy, after a negative colonoscopy(compulsory in our institution). Controls were evaluated for non-bleeding indications. Known or suspected chronic inflammatory conditions and medication that could harm the gut were excluded. During capsule endoscopy, small bowel ulcerative lesions were counted thoroughly and classified according to Graham classification. Other small bowellesions were also recorded. Peptic ulcer bleeding was controlled endoscopically, when adequate, proton pump inhibitors were started in both cases and controls, and Helicobacter pylori eradicated whenever present. Both cases and controls were followed up for a year. In case of bleeding recurrence upper gastrointestinal endoscopy was repeated and whenever it remained unexplained it was followed by repeat colonoscopy and capsule endoscopy.RESULTS: Forty(67%) cases and 18(30%) controls presented small bowel erosions(P = 0.0001), while 22(37%) cases and 4(8%) controls presented small bowel ulcers(P < 0.0001). Among non-steroidal antiinflammatory drug(NSAID) consumers, 39(95%) cases and 17(33%) controls presented small bowel erosions(P < 0.0001), while 22(55%) cases and 4(10%) controls presented small bowel ulcers(P < 0.0001). Small bowel ulcerative lesions were infrequent among patients not consuming NSAIDs. Mean entry hemoglobin was 9.3(SD = 1.4) g/d L in cases with small bowel ulcerative lesions and 10.5(SD = 1.3) g/dL in those without(P = 0.002). Cases with small bowel ulcers necessitate more units of packed red blood cells. During their hospitalization, 6(27%) cases with small bowel ulcers presented bleeding recurrence most possibly attributed to small bowel ulcers, nevertheless 30-d mortality was zero. Presence of chronic obstructive lung disease and diabetes was related with unexplained recurrence of hemorrhage in logistic regression analysis, while absence of small bowel ulcers was protective(relative risk 0.13, P = 0.05).CONCLUSION: Among NSAID consumers, more bleeders than non-bleeders with peptic ulcers present small bowel ulcers; lesions related to more severe bleeding and unexplained episodes of bleeding recurrence. | Panagiotis Tsibouris Chissostomos Kalantzis Periklis Apostolopoulos Antonios Zalonis Peter Edward Thomas Isaacs Mark Hendrickse Georgios Alexandrakis | 2014 | World Journal of Gastrointestinal Endoscopy2014，6，12： | 6 |
| 3 | Capsule endoscopy retention as a helpful tool in the management of a young patient with suspected small-bowel disease显示文摘Capsule endoscopy is an easy and painless procedure permitting visualization of the entire small-bowel during its normal peristalsis. However, important problems exist concerning capsule retention in patients at risk of small bowel obstruction. The present report describes a young patient who had recurrent episodes of overt gastrointestinal bleeding of obscure origin, 18 years after small bowel resection in infancy for ileal atresia. Capsule endoscopy was performed, resulting in capsule retention in the distal small bowel. However, this event contributed to patient management by clearly identifying the site of obstruction and can be used to guide surgical intervention, where an anastomotic ulcer is identified. | Chryssostomos Kalantzis Periklis Apostolopoulos Panagiota Mavrogiannis Dimitrios Theodorou Xenophon Papaharalampous Ioannis Bramis Nikolaos Kalantzis | 2007 | World Journal of Gastroenterology2007，13，8： | 5 |
| 4 | Inflammatory biomarkers: impact for diabetes and diabetic vascular disease显示文摘物理迟钝和坐着的生活方式被相信是为肥胖, type-2 糖尿病,和新陈代谢的症候群的出现的独立风险因素[13 ] 。type-2 糖尿病的发生由长期的多糖症和葡萄糖不耐描绘了,与肥胖同时增加了,并且 2010, 2.85 亿个人以前与 3000 万 25 年相比与 type-2 糖尿病被诊断[4 ] 。甚至与 statin 治疗, type-2 糖尿病被显示了导致加速的动脉粥样硬化和脉管的疾病的过多的风险[5 ] 。象多糖症和葡萄糖不耐, hyperlipidemia,肥胖,和高血压那样的风险因素导致糖尿病的脉管的疾病[6 ] 。有糖尿病和新陈代谢的控制的一样的持续时间的一些病人为什么有通过多重脉管的区域散布或限制了到仅仅一脉管的领土的动脉粥样硬化的不同程度,很好没被理解。在有 type-2 糖尿病的人的 statins 和 fibrates 的使用是有利的,尽管有糖尿病的脉管的疾病的前进[7 ] 。然而, pioglitazone 和 statins 的合作管理在 intima 媒介厚度和 endothelial 功能改进提供回归[8 ] 。另外,煽动性的标记的减少(C 反应的蛋白质;CRP, P-selectin, adiponectin,和高密度脂蛋白胆固醇) 并且 triglyceride 层次与增加的心血管的风险因素在病人被注意[8 ] 。 | Marijan Bosevski Lily Stojanovska Vasso Apostolopoulos | 2015 | Acta Biochimica et Biophysica Sinica2015，47，12： | 4 |
| 5 | Leukocyte populations and IL-6 in the tumor microenvironment of an orthotopic colorectal cancer model显示文摘Colorectal 癌症(CRC ) 是世界范围的一个主要健康问题。它经常由于它的无征状的性质晚被诊断。就象所有癌症,有免疫力的反应被包含;在 CRC,如果这有免疫力的回答为疾病前进有利或相反,然而,它是未知的。在这研究,在 mesenteric 淋巴节点(MLN ) 和 Peyers 补丁的有免疫力的反应在一个 orthotopic 鼠标模型在 CRC 的开发期间被调查。CRC 被把 CT26 房间注入 BALB/c 老鼠的盲肠墙导致。流动 cytometry 被用来分析在 MLN 和 Peyers 补丁涉及肿瘤免疫的白血球人口。为 immunohistochemistry 的低温恒温器节从盲肠和冒号被准备从导致 CRC 并且假冒操作动物。老鼠 CT26 房间线生产的 Cytokines 在 vitro 并且在 vivo 被测量。房间在 CRC 组在 MLN 和 Peyers 补丁被发现的 CD8 +/TCR+ 和 CD49b +/TCR( 生来的杀手) 的数字的重要增加。另外, T 房间在从假冒操作老鼠的冒号纸巾的薄板 propria 是在场的,但是与 CRC 从老鼠在冒号纸巾不在。肿胀的纸巾的 Immunohistochemical 分析显示出嗜曙红血球, CD69 + T 房间,和 CD11b + 房间渗入。在 vitro 并且在 vivo CT26 肿瘤,房间是 interleukin (IL )-6 积极。另外,渗入肿瘤的 CD45 + 房间也是 IL-6 积极。在摘要,对 CRC 和在肿瘤免疫被含有的关键受动器淋巴细胞的有免疫力的反应的动力学被表明。而且, IL-6 是在肿瘤微型环境以内在场的关键 cytokine。 | Sarah Miller Paul V. Senior Monica Prakash Vasso Apostolopoulos Samy Sakkal Kulmira Nurgali | 2016 | Acta Biochimica et Biophysica Sinica2016，48，4： | 4 |
| 6 | Evaluation of capsule endoscopy in active, mild-to-moderate, overt, obscure GI bleeding <ce:link locator='fx1'/>显示文摘 | Periklis Apostolopoulos Christos Liatsos Ian M. Gralnek Chrissostomos Kalantzis Eleftheria Giannakoulopoulou Georgios Alexandrakis Panagiotis Tsibouris Evagelos Kalafatis Nikolaos Kalantzis | 2007 | Gastrointestinal Endoscopy2007，，6： | 3 |
| 7 | Validation of the Capsule Endoscopy Crohn’s Disease Activity Index (CECDAI or Niv score): a multicenter prospective study显示文摘 | Y. Niv S. Ilani Z. Levi M. Hershkowitz E. Niv Z. Fireman S. O’Donnel C. O’Morain R. Eliakim E. Scapa N. Kalantzis C. Kalantzis P. Apostolopoulos E. Gal | 2012 | Endoscopy2012，，01： | 2 |
| 8 | Hollow-core antiresonant terahertz fiber-based TOPAS extruded from a 3D printer using a metal 3D printed nozzle显示文摘We report the use of a terahertz(THz)transparent material,cyclic olefin copolymer(COC or TOPAS),for fabricating a hollow-core antiresonant fiber that provides an electromagnetic wave guidance in the THz regime.A novel fabrication technique to realize a hollow-core antiresonant polymer optical fiber(HC-ARPF)for THz guidance is proposed and demonstrated.The fiber is directly extruded in a single-step procedure using a conventional fused deposition modeling 3 D printer.The fiber geometry is defined by a structured nozzle manufactured with a metal 3 D printer,which allows tailoring of the nozzle design to the various geometries of microstructured optical fibers.The possibility to use the HC-ARPF made from TOPAS for guiding in the THz region is theoretically and experimentally assessed through the profile of mode simulation and time-frequency diagram(spectrogram)analysis. | WANVISA TALATAISONG JON GORECKI LIEKE D.VAN PUTTEN RAND ISMAEEL JAMES WILLIAMSON KATIE ADDINALL DANIEL SCHWENDEMANN MARTYNAS BERESNA VASILIS APOSTOLOPOULOS GILBERTO BRAMBILLA | 2021 | Photonics Research2021，9，8： | 2 |
| 9 | Tensile and low cycle fatigue behavior of corroded reinforcing steel bars S400显示文摘 | C.A. Apostolopoulos M.P. Papadopoulos | 2006 | Construction and Building Materials2006，，4： | 2 |
| 10 | Vitamin D enzymes (CYP27A1, CYP27B1, and CYP24A1) and receptor expression in non-melanoma skin cancer显示文摘The relationship between vitamin D metabolic enzymes (CYP27A1, CYP27B1, and CYP24A1) and vitamin D receptor (VDR) in nonmelanoma skin cancer (NMSC) development and progression is not entirely clear. However, several clinical studies and in vitro reports indicate a connection between vitamin D metabolic key players and NMSCs by demonstrating inhibitory effects on tumor cells and positive effects in skin cancer prevention of higher circulatory 25-hydroxyvitamin D [1]. Vitamin D synthesis is mediated via mitochondrial cytochrome P450 family hydroxylase enzymatic reactions: anabolic and catabolic hydroxylases (CYP27A1, CYP27B1, and CYP24A1). | Natalie Nemazannikova Gregory L. Blatch Crispin R. Dass Rodney Sinclair Vasso Apostolopoulos | 2019 | Acta Biochimica et Biophysica Sinica2019，51，4： | 2 |
| 11 | Application of the Firefly Algorithm for Solving the Economic Emissions Load Dispatch Problem显示文摘 | Theofanis Apostolopoulos Aristidis Vlachos Hajo Broersma | 2010 | International Journal of Combinatorics2010，，： | 1 |
| 12 | Design of peptide-based vaccines for cancer显示文摘 | Pietersz GA Pouniotis DS Apostolopoulos V | 2006 | Curt Med Chem2006，13，14： | 1 |
| 13 | Corrosion of reinforcing steel and low cycle fatigue behaviour显示文摘 | APOSTOLOPOULOS C A MICHALOPOULOS D | 2007 | Materials andCorrosion2007，58，6： | 1 |
| 14 | Crystal structure of a noncanonical low affinity peptide complexed with MHC class I:a new approach for vaccine design显示文摘 | Apostolopoulos V Yu M Corper A L | 2002 | J Mol Biol2002，318，5： | 1 |
| 15 | Thermodynamics of water and ethanol adsorption on four starches as model biomass separation systems 显示文摘 | V Rebar ER Fischbach D Apostolopoulos | 1984 | Biotechnology and Bioengineering1984，26，： | 1 |
| 16 | Reliable video communication over lossy packet networks using multiple state encoding and path diversity 显示文摘 | Apostolopoulos J G | 2001 | Proceedings of SPIE2001，4310，： | 1 |
| 17 | Induction of HLA-A2- restricted CTLs to the mucin 1 human breast cancer antigen 显示文摘 | Apostolopoulos V Karanikas V Haurum J S | 1997 | J Immunol1997，159，11： | 1 |
| 18 | Quality-optimizedand secure end-to-end authentication for media delivery显示文摘 | SUN Q APOSTOLOPOULOS J CHEN C W | 2008 | Proceed-ings of the IEEE2008，96，1： | 1 |
| 19 | RopiVacaine compared to lidocaine for tonsillectomyundel'loder'armesthesia显示文摘 | Apostolopoulos K Labropoulon E Samaan R etal | 2003 | Eur Arch Otorhinolaryngol2003，260，： | 1 |
| 20 | Tourism in crisis:Managing the effects of terrorism显示文摘 | SONMEZ S F APOSTOLOPOULOS Y TARLOW P | 1999 | Jour-nal of Travel Research1999，38，1： | 1 |
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