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| 1 | History of the infantile hepatic hemangioma:From imaging to generating a differential diagnosis显示文摘We aim to provide an up-to-date summary of infantile hepatic hemangioma(IHH) and its misnomers and to dialectically present the differential diagnosis of these rare entities of the liver.Eligible peer-reviewed articles on hepatic infantile hemangiomas,published between 2000 and 2015,were reviewed for this study.IHH is the most common hepatic vascular tumor in children.Once a liver mass is identified in an infant,the differential diagnosis ranges from vascular malformations to benign and malignant tumors including mesenchymal hamartoma,hepatoblastoma,metastatic neuroblastoma,so careful physical examination,imaging studies,and,if indicated,tumor markers and biopsy,are of pivotal importance to ascertain the correct diagnosis.Despite the benign nature of IHHs,some of these lesions may demand medical and/or surgical intervention,especially for multiple and diffuse IHH.Complications can include hepatomegaly,hypothyroidism and cardiac failure.Therefore,a close follow-up is required until complete involution of the lesions.We propose an algorithm to guide the physicians towards the proper management of hepatic lesions. | Maria Gnarra Gerald Behr Alison Kitajewski June K Wu Sudha A Anupindi Carrie J Shawber Nick Zavras Dimitrios Schizas Chris Salakos Konstantinos P Economopoulos | 2016 | World Journal of Clinical Pediatrics2016，5，3： | 27 |
| 2 | p53-mediated transcriptional regulation and activation of the actin cytoskeleton regulatory RhoC to LIMK2 signaling pathway promotes cell survival显示文摘响应 DNA 损坏的房间命运的中央仲裁人是 p53,它调整涉及房间周期拘捕,幸存和 apoptosis 的基因的表示。尽管 DNA 损坏开始的许多回答被描绘了,肌动朊细胞骨架管理者的角色大部分是未知的。我们现在显示出那 RhoC 和秘鲁利玛机场之代号 kinase (LIMK2 ) 2 是 genotoxic 代理人导致的直接 p53 目标基因。尽管 RhoC 和 LIMK2 在肌动朊细胞骨架规定有生长得很好的角色,我们的结果显示 LIMK2 的激活也有支持幸存的功能追随者 DNA 损坏。由调停 siRNA 的击倒或选择的药理学封锁的 LIMK 抑制敏化房间到无线电 -- 或化疗,以便当与 LIMK 抑制结合了时,当单身地管理了时,是尚不致命的治疗导致了房间死亡。我们的调查结果建议把 LIMK 禁止者与 genotoxic 治疗相结合能比单个代理人的管理更有效,并且加亮在肌动朊细胞骨架管理者和 DNA 之间的一个新奇连接导致损坏的房间幸存机制。 | Daniel R Croft Diane Crighton Michael S Samuel Filipe C Lourenco June Munro Jenifer Wood Karim Bensaad Karen H Vousden Owen J Sansom Kevin M Ryan Michael F Olson | 2011 | Cell Research2011，21，4： | 3 |
| 3 | Thompson CB: The B7 and CD28 receptor families显示文摘 | June C H Bluestone J A Nadler L M | 1994 | Immunol Today1994，15，7： | 1 |
| 4 | Dynamic model- ing of large - scale mageto theological damper systems for civil engineering applications 显示文摘 | Yang G Q Spencer B F June H J | 2004 | Journal of Engineering Mechanics2004，130，9： | 1 |
| 5 | Osteop rotegerin inhibits ar- tery calcigtication induced by warfarin and by vitamin D 显示文摘 | Price P A June H H Buekley J R | 2001 | Arte- rioseler Thromb Vasc Biol2001，21，10： | 1 |
| 6 | Osteoprotegerin inhibits artery calcification induced by warfarin and by vitamin D 显示文摘 | Price P A June H H Buckley J R | 2001 | Arterioscler 3hromb Vasc Biol2001，21，10： | 1 |
| 7 | Considerations for the clinical applicationof chimeric antigen receptor T cells: observations froma recombinant DNA Advisory Committee Symposiumheld June 15,2010 显示文摘 | Ertl H C Zaia J? Rosenberg S A June C H Dotti G Kahn J | 2011 | Cancer Res2011，71，： | 1 |
| 8 | Blockade of CD28 during in vitro activation of encephalitogenic T cells or after disease onset ameliorates experimental autoimmune encephalomyelitis 显示文摘 | Perrin P June C Maldonado J | 1999 | J Immunol1999，163，17： | 1 |
| 9 | Osteoprotegerin inhibits artery calcification induced by warfarin and by vitamin D显示文摘 | June H Buckley J | 2001 | Arterioscler Thromb Vasc Biol2001，21，10： | 1 |
| 10 | Prolonged survival of class Ⅱ transactivator-deficient cardiac allografts显示文摘 | JUNE BRICKEY W FELIX N J GRIFFITHS R | 2002 | Transplantation2002，74，： | 1 |
| 11 | Engineering lympho- cyte subsets: tools, trials and tribulations显示文摘 | June C H Blazar B R Riley J L | 2009 | Nature Re- views Immunology2009，9，10： | 1 |
| 12 | GUARD CELL SIGNAL TRANSDUCTION显示文摘 | Julian I Schroeder Gethyn J Allen Veronique Hugouvieux June M Kwak David Waner | 2001 | Annual Review of Plant Physiology and Plant Molecular Biology2001，，： | 1 |
| 13 | Guard cell abscisic acid signalling and engineering drought hardiness in plants显示文摘 | Julian I Schroeder June M Kwak Gethyn J Allen | 2001 | Nature2001，410，： | 1 |
| 14 | Production of theisoflavones genistein and daidzein in non-legume dicotand monocot tissues显示文摘 | Oliver Y Woosuk J June S | 2000 | Plant Physiology2000，124，2： | 1 |
| 15 | Clinical perspec- tives for regulatory T cells in transplantation tolerance 显示文摘 | HIPPEN K L RILEY J L JUNE C H | 2011 | Semin Immunol2011，23，6： | 1 |
| 16 | Satellite observations of the microwave emissivity of a semi-arid land surface显示文摘 | June C Morland David I F Grimes T J Hewison | 2001 | Remote Sensing of Environment2001，77，1： | 1 |
| 17 | Dietary resistant starch upregulates total GLP-1 and PYY in a sustained day-long manner through fermentation in rodents显示文摘 | June Zhou Roy J M Richard T T | 2008 | American Journal of Physiology2008，295，5： | 1 |
| 18 | simultaneous measurement of strain and temperature using a single fiber Bragg grating written in an erbium:ytterbium-doped fiber显示文摘 | June J Nam H Lee J H | 2000 | Appl Opt2000，39，7： | 1 |
| 19 | Guard cellabscisic acid signalling and engineering drought hardiness inplants 显示文摘 | JulDian I Schroeder june M Kwak Gethyn J Mien | 2001 | Nature2001，410，： | 1 |
| 20 | Prolonged survival of class Ⅱ transactivator-deficient cardiac allografts显示文摘 | June Brickey W Felix N J Griffiths R | 2002 | Transplantation2002，74，9： | 1 |
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