|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | p53-mediated transcriptional regulation and activation of the actin cytoskeleton regulatory RhoC to LIMK2 signaling pathway promotes cell survival显示文摘响应 DNA 损坏的房间命运的中央仲裁人是 p53,它调整涉及房间周期拘捕,幸存和 apoptosis 的基因的表示。尽管 DNA 损坏开始的许多回答被描绘了,肌动朊细胞骨架管理者的角色大部分是未知的。我们现在显示出那 RhoC 和秘鲁利玛机场之代号 kinase (LIMK2 ) 2 是 genotoxic 代理人导致的直接 p53 目标基因。尽管 RhoC 和 LIMK2 在肌动朊细胞骨架规定有生长得很好的角色,我们的结果显示 LIMK2 的激活也有支持幸存的功能追随者 DNA 损坏。由调停 siRNA 的击倒或选择的药理学封锁的 LIMK 抑制敏化房间到无线电 -- 或化疗,以便当与 LIMK 抑制结合了时,当单身地管理了时,是尚不致命的治疗导致了房间死亡。我们的调查结果建议把 LIMK 禁止者与 genotoxic 治疗相结合能比单个代理人的管理更有效,并且加亮在肌动朊细胞骨架管理者和 DNA 之间的一个新奇连接导致损坏的房间幸存机制。 | Daniel R Croft Diane Crighton Michael S Samuel Filipe C Lourenco June Munro Jenifer Wood Karim Bensaad Karen H Vousden Owen J Sansom Kevin M Ryan Michael F Olson | 2011 | Cell Research2011，21，4： | 3 |
| 2 | Effect of group IV elements on the cutting characteristics ofTi(C, N) cermet tools and reliability analysis显示文摘 | WON T K JUNE S P SHINHOO K | 2005 | Journal of Materials Processing Technology2005，166，： | 1 |
| 3 | Efficacy of topical 5% imiquimod cream for the treatment of nodular basal cell carcinoma显示文摘 | Stephen S June R Steven K | 2002 | Arch Dermatol2002，138，： | 1 |
| 4 | Considerations for the clinical applicationof chimeric antigen receptor T cells: observations froma recombinant DNA Advisory Committee Symposiumheld June 15,2010 显示文摘 | Ertl H C Zaia J? Rosenberg S A June C H Dotti G Kahn J | 2011 | Cancer Res2011，71，： | 1 |
| 5 | Serum alanine aminotransferase predicts interventricular septum thickness and left ventricular mass in patients with nonalcoholic fatty liver disease显示文摘 | Juan Ybarra Sandra Fernández Joan Sánchez-Hernández June H. Romeo Carlos Ballesta-Lopez Javier Guell Fermin Mearin | 2014 | European Journal of Gastroenterology & Hepatology2014，，6： | 1 |
| 6 | A video camera system with enhanced zoom tracking and auto white balance显示文摘 | Yoon K K June S L Aldo W M | 2002 | IEEE Transactions on Consumer Electronics2002，48，3： | 1 |
| 7 | Going viral: chimeric antigen receptor T-cell therapy for hematological malignancies显示文摘 | Gill S June CH | 2015 | Immunol Rev2015，263，1： | 1 |
| 8 | Antibiotic resistance in triclosan tolerant fecal coliforms isolated from surface waters near wastewater treatment plant outflows显示文摘 | June H M James D S | 2013 | Ecotoxicology En?vironment Safafety2013，88，1： | 1 |
| 9 | 显示文摘 | Kohei S Toshihiro T June N | 2000 | Pediatr Res2000，48，4： | 1 |
| 10 | Production of theisoflavones genistein and daidzein in non-legume dicotand monocot tissues显示文摘 | Oliver Y Woosuk J June S | 2000 | Plant Physiology2000，124，2： | 1 |
| 11 | Randomised,double blind,placebo controlled study of fluticasone propionate in patients with moderate to severe chronic obstructive pulmonary disease:the ISOLDE trial 显示文摘 | Burge PS Calverley PM Junes PW Spencer S Anderson JA Maslen TK | 2000 | BMJ2000，320，： | 1 |
| 12 | The predictive utility of com- puter- simulated exercinieal technique 显示文摘 | Sarah A G Lisa P D June A S | 2003 | J Dent Educ2003，67，11： | 1 |
| 13 | Going viral : chimeric antigen receptor T- cell therapy for hematological malignancies 显示文摘 | Gill S June CH | 2015 | Immunol Rev2015，263，1： | 1 |
| 14 | Development of a questionnaire to assess knowledge, attitude and practice in American Indian children显示文摘 | June S Comel CE Marys | 1999 | Am J Clin Nutr1999，69，4： | 1 |
| 15 | Dynamic Mechanical Properties of Poly(vinyl chloride) and Polyurethane Carboxylate blends显示文摘 | S June Kim Byung Kyu Kim Hart Mo Jeong | 1994 | Journal of Applied Polymer Science1994，51，13： | 1 |
| 16 | Analysis of small molecules by desorption/ionization on mesoporous silicate (DIOM)-mass spectrometry(MS) 显示文摘 | Chang S L Kyoung K K June H K | 2007 | Microporous Mesoporous Mater2007，98，1： | 1 |
| 17 | Going viral: chimeric antigen receptor T-cell therapy for hematological malignancies显示文摘 | Gill S June CH | 2015 | Immunol Rev2015，2631，： | 1 |
| 18 | Heterotypic adherence between humanB- lymphoblastic and pre- B- lymphoblastic cells and marrow stromal cells is a biphasic event:integrin very late antigen- 4 alpha mediates only the early phase of the heterotypic adhesion显示文摘 | Patrick CW Jr June ja Hs Lee S | 1995 | Blood1995，85，1： | 1 |
| 19 | Effect of the sur- face morphology of seed and mask layers on InP grown on Si by epitaxial lateral overgrowth 显示文摘 | JUNE S C HU C WANGZ C etal | 2012 | Journal of Elec- tronic Materials2012，41，9： | 1 |
| 20 | Going viral: chimeric antigen receptor T-cell therapy for hematological malignancies显示文摘 | Gill S June CH | 2015 | Immunol Rev2015，263，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员