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4篇 您的检索式:作者名="Joseph M Lane"
    题名 作者 年代 出处 被引量
1Current concepts on osteonecrosis of the femoral head显示文摘It is estimated that 20000 to 30000 new patients are diagnosed with osteonecrosis annually accounting for approximately 10% of the 250000 total hip arthroplasties done annually in the United States. Thelack of level 1 evidence in the literature makes it difficult to identify optimal treatment protocols to manage patients with pre-collapse avascular necrosis of the femoral head, and early intervention prior to collapse is critical to successful outcomes in joint preserving procedures. There have been a variety of traumatic and atraumatic factors that have been identified as risk factors for osteonecrosis, but the etiology and pathogenesis still remains unclear. Current osteonecrosis diagnosis is dependent upon plain anteroposterior and frog-leg lateral radiographs of the hip, followed by magnetic resonance imaging(MRI). Generally, the first radiographic changes seen by radiograph will be cystic and sclerotic changes in the femoral head. Although the diagnosis may be made by radiograph, plain radiographs are generally insufficient for early diagnosis, therefore MRI is considered the most accurate benchmark. Treatment options include pharmacologic agents such as bisphosphonates and statins, biophysical treatments, as well as joint-preserving and joint-replacing surgeries. the surgical treatment of osteonecrosis of the femoral head can be divided into two major branches: femoral head sparing procedures(FHSP) and femoral head replacement procedures(FHRP). In general, FHSP are indicated at pre-collapse stages with minimal symptoms whereas FHRP are preferred at post-collapse symptomatic stages. It is difficult to know whether any treatment modality changes the natural history of core decompression since the true natural history of core decompression has not been delineated.Joaquin Moya-Angeler Arianna L Gianakos Jordan C Villa Amelia Ni Joseph M Lane 2015World Journal of Orthopedics2015,6,8:94
2Need to Knowledge (NtK)Model: an evidence-based framework for generating technological innovations withsocio-economic impacts显示文摘Jennifer L Flagg Joseph P Lane Michelle M 2013Implementation science: IS2013,8,1:1
3Corn as a production system for human and animal vaccines显示文摘Stephen J Streatfield Jeffrey R Lane Christopher A Brooks Donna K Barker Miranda L Poage Jocelyne M Mayor Barry J Lamphear Carol F Drees Joseph M Jilka Elizabeth E Hood John A Howard 2002Vaccine2002,,7:1
4Biosynthetic bone grafting显示文摘Joseph M Lane MD Ember T 1999Clin Orthop[J]1999,,367:1
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