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| 1 | Abdominal applications of diffusion-weighted magnetic resonance imaging: Where do we stand?显示文摘Diffusion-weighted imaging (DWI) is one of the magnetic resonance imaging (MRI) sequences providing qualitative as well as quantitative information at a cellular level. It has been widely used for various applications in the central nervous system. Over the past decade, various extracranial applications of DWI have been increasingly explored, as it may detect changes even before signal alterations or morphological abnormalities become apparent on other pulse sequences. Initial results from abdominal MRI applications are promising, particularly in oncological settings and for the detection of abscesses. The purpose of this article is to describe the clinically relevant basic concepts of DWI, techniques to perform abdominal DWI, its analysis and applications in abdominal visceral MR imaging, in addition to a brief overview of whole body DWI MRI. | Ajaykumar C Morani Khaled M Elsayes Peter S Liu William J Weadock Janio Szklaruk Jonathan Russell Dillman Asra Khan Thomas L Chenevert Hero K Hussain | 2013 | World Journal of Radiology2013，5，3： | 12 |
| 2 | 印度板块和亚洲大陆在何时何地碰撞显示文摘印度板块和亚洲大陆的初始碰撞时间是所有相关的喜马拉雅-西藏造山体系演化模式的主控条件,并严重影响到对众多与青藏高原隆升和东亚大陆挤出相关的地质过程速率的解释,以及对新生代全球气候变化的理解。尽管印度板块和亚洲大陆汇聚的速率在55Ma突然减缓被广泛地认为是初始碰撞的标志,但这次碰撞所造成的主要构造效应直到20多个百万年以后才显现出来。对印度板块和亚洲大陆相对位置的重新估算,表明它们在55Ma时并没有达到可以彼此发生碰撞的距离。基于来自西藏新的野外证据和对已有数据的重新评估,认为初始碰撞发生在始新世—渐新世之交(约34Ma),并对55Ma时发生的地质事件提出了另一种解释。 | Jonathan C Aitchison Jason R Ali Aileen M Davis 戴紧根(译) 赵西西(校) | 2008 | 地质通报2008，27，9： | 8 |
| 3 | Clinical outcomes following salvage Gamma Knife radiosurgery for recurrent glioblastoma显示文摘Glioblastoma multiforme(GBM) is the most common malignant primary brain tumor with a survival prognosis of 14-16 mo for the highest functioning patients. Despite aggressive, multimodal upfront therapies, the majority of GBMs will recur in approximately six months. Salvage therapy options for recurrent GBM(r GBM) are an area of intense research. This study compares recent survival and quality of life outcomes following Gamma Knife radiosurgery(GKRS) salvage therapy. Following a Pub Med search for studies usingGKRS as salvage therapy for malignant gliomas, nine articles from 2005 to July 2013 were identified which evaluated rG BM treatment. In this review, we compare overall survival following diagnosis, overall survival following salvage treatment, progression-free survival, time to recurrence, local tumor control, and adverse radiation effects. This report discusses results for rG BM patient populations alone, not for mixed populations with other tumor histology grades. All nine studies reported median overall survival rates(from diagnosis, range:16.7-33.2 mo; from salvage, range:9-17.9 mo). Three studies identified median progression-free survival(range:4.6-14.9 mo). Two showed median time to recurrence of GBM. Two discussed local tumor control. Six studies reported adverse radiation effects(range:0%-46% of patients). The greatest survival advantages were seen in patients who received GKRS salvage along with other treatments, like resection or bevacizumab, suggesting that appropriately tailored multimodal therapy should be considered with each rG BM patient. However, there needs to be a randomized clinical trial to test GKRS for rG BM before the possibility of selection bias can be dismissed. | Erik W Larson Halloran E Peterson Wayne T Lamoreaux Alexander R MacKay Robert K Fairbanks Jason A Call Jonathan D Carlson Benjamin C Ling John J Demakas Barton S Cooke Christopher M Lee | 2014 | World Journal of Clinical Oncology2014，5，2： | 5 |
| 4 | Efficacy of boceprevir, an NS3 protease inhibitor, in combination with peginterferon alfa-2b and ribavirin in treatment-naive patients with genotype 1 hepatitis C infection (SPRINT-1): an open-label, randomised, multicentre phase 2 trial显示文摘 | Paul Y Kwo Eric J Lawitz Jonathan McCone Eugene R Schiff John M Vierling David Pound Mitchell N Davis Joseph S Galati Stuart C Gordon Natarajan Ravendhran Lorenzo Rossaro Frank H Anderson Ira M Jacobson Raymond Rubin Kenneth Koury Lisa D Pedicone Clifford | 2010 | The Lancet2010，，9742： | 3 |
| 5 | A next-generation marker genotyping platform(AmpSeq)in heterozygous crops:a case study for marker-assisted selection in grapevine显示文摘Marker-assisted selection(MAS)is often employed in crop breeding programs to accelerate and enhance cultivar development,via selection during the juvenile phase and parental selection prior to crossing.Next-generation sequencing and its derivative technologies have been used for genome-wide molecular marker discovery.To bridge the gap between marker development and MAS implementation,this study developed a novel practical strategy with a semi-automated pipeline that incorporates trait-associated single nucleotide polymorphism marker discovery,low-cost genotyping through amplicon sequencing(AmpSeq)and decision making.The results document the development of a MAS package derived from genotyping-by-sequencing using three traits(flower sex,disease resistance and acylated anthocyanins)in grapevine breeding.The vast majority of sequence reads(⩾99%)were from the targeted regions.Across 380 individuals and up to 31 amplicons sequenced in each lane of MiSeq data,most amplicons(83 to 87%)had<10%missing data,and read depth had a median of 220–244×.Several strengths of the AmpSeq platform that make this approach of broad interest in diverse crop species include accuracy,flexibility,speed,high-throughput,low-cost and easily automated analysis. | Shanshan Yang Jonathan Fresnedo-Ramíre Minghui Wang Linda Cote Peter Schweitzer Paola Barba Elizabeth M Takacs Matthew Clark James Luby David C Manns Gavin Sacks Anna Katharine Mansfield Jason Londo Anne Fennell David Gadoury Bruce Reisch Lance Cadle-Davidson Qi Sun | 2016 | Horticulture Research2016，3，1： | 2 |
| 6 | Physical Activity Constrains among Latinos 显示文摘 | Michelle G H Myron F F Jonathan M C | 2013 | Journal of Leisure Re- search2013，45，1： | 1 |
| 7 | Follicle stimula ting hormone (FSH) actives the P mitogen activated protein ki- nase pathway, inducing small heat shock protein phosphorylation and cell rounding in immature rat ovarian granulosa cells显示文摘 | Evelyn T M Joshu A C Jonathan C R J | 1998 | En docrinology1998，139，7： | 1 |
| 8 | Pectin is not pectin: A randomized trial on the effect of different physicochemical properties of dietary fiberon appetite and energy intake显示文摘 | WANDERS A J FESKENS E J M JONATHAN M C | 2014 | Physiology & Behavior2014，，128： | 1 |
| 9 | Constructing con- trollers for physical nmhilegged robots using the ENSO neu- roevolution approach显示文摘 | Vinod K V Jonathan H Rohcrt M c| al | 2012 | Evolutionary Intelligence2012，，5： | 1 |
| 10 | Keeping time with the human genome显示文摘 | Jonathan D C Charalambos P K Repert S M | 2001 | Nature2001，409，6822： | 1 |
| 11 | Proton pump inhibitors and severehypomagnesaemia 显示文摘 | TIM C JONATHAN M | 2011 | Curr Opin Gastroenterol2011，27，2： | 1 |
| 12 | Reactive navigation and opportunistic localization for autonomous underground mining vehicles 显示文摘 | Jonathan M R Elliot S D Peter I C | 2002 | Information Sciences2002，145，： | 1 |
| 13 | Proton pump inhibitors and severe hypomag- nesaemia 显示文摘 | Tim C Jonathan M | 2011 | Curr Opin Gastroenterol2011，27，2： | 1 |
| 14 | Bedside detection of awareness in the vegetative state显示文摘 | Andrew M Goldfine Jonathan D Victor Mary M Conte Jonathan C Bardin Nicholas D Schiff | 2012 | The Lancet2012，，9827： | 1 |
| 15 | Optimization of point target tracking filters显示文摘 | Charlene E C Jerry S Jonathan M M | 2000 | IEEE Transactions on AES2000，36，1： | 1 |
| 16 | DHA Exacerbates Experimentally Induced Colitis in SMAD3-/-Mice显示文摘 | HILLARY L W SARAH J M JONATHAN C | 2010 | FASEB Journal2010，24，： | 1 |
| 17 | Striping within the network subsystem显示文摘 | C Brendan S T Jonathan M S | 1995 | IEEE Network Magazine1995，9，4： | 1 |
| 18 | Photoelectrochemical determination of analysis of ascorbic acid 显示文摘 | Jonathan A C Wu M Richard G C | 1998 | Analytical Chemistry1998，70，14： | 1 |
| 19 | IL-27, a Heterodimeric Cytokine Composed of EBI3 and p28 Protein, Induces Proliferation of Naive CD4 + T Cells显示文摘 | Stefan Pflanz Jackie C Timans Jeanne Cheung Rency Rosales Holger Kanzler Jonathan Gilbert Linda Hibbert Tatyana Churakova Marilyn Travis Elena Vaisberg Wendy M Blumenschein Jeanine D Mattson Janet L Wagner Wayne To Sandra Zurawski Terrill K McClanahan Dan | 2002 | Immunity2002，，6： | 1 |
| 20 | Feature-subspace aggregating: Ensembles for stable and unstable learners 显示文摘 | KAI M T JONATHAN R W SWEE C T | 2011 | Machine Learning2011，82，3： | 1 |
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