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| 1 | Transcriptomics-based identification of WRKY genes and characterization of a salt and hormone-responsive PgWRKY1 gene in Panax ginseng显示文摘WRKY 蛋白质属于一个抄写因素(TF ) 家庭和戏在许多植物过程,对不能生活、关於生命的压力的包括的植物回答,以及第二等的新陈代谢的动态角色。然而,在人参属人参 C ·迈耶的 WRKY 基因都没迄今为止被报导。在这研究,从甲基 jasmonate (MeJA ) 的很多 WRKY unigenes 对待偶然这种的根 transcriptome 用下一代的定序被识别技术。编码 WRKY 蛋白质的 48 有希望的 WRKY unigenes 的一个总数被消除冤屈和不完全的开的读物框架(ORF ) 获得。种系发生的分析揭示 48 WRKY TF,包括 11 组我, 36 组 II,和 1 组 III。而且,指定为 PgWRKY1 的一 MeJA 应答的 unigene 被克隆并且描绘。它包含 1077 bp 的全部 ORF 并且编码 358 氨基酸残余的多肽。PgWRKY1 蛋白质包含由保存氨基酸顺序主题 WRKYGQK 和 C 2 H 2-type 锌手指主题属于 WRKY 亚群 II-d。在洋葱和烟草外皮房间的 PgWRKY1-GFP 熔化蛋白质的 Subcellular 本地化表明 PgWRKY1 在原子核是只在场的。量的即时聚合酶链反应分析证明 PgWRKY1 的表示与叶子,茎,和种子相比在根和侧面的根是相对更高的。重要地, PgWRKY1 表示被水杨酸显著地导致酸, abscisic 酸,和 NaCl,而是由 MeJA 处理的 downregulated。这些结果建议 PgWRKY1 可能是对荷尔蒙和盐压力作出回应的多重压力可诱导的基因。 | Mohammed Nuruzzaman Hongzhe Cao Hao Xiu Tiao Luo Jijia Li Xianghui Chen Junli Luo Zhiyong Luo | 2016 | Acta Biochimica et Biophysica Sinica2016，48，2： | 12 |
| 2 | Ginsenoside Rh2 inhibits proliferation and induces apoptosis in human leukemia cells via TNF-~ signaling pathway显示文摘人参皂甙 Rh2,从人参属人参提取的 triterpene saponin,对多重癌症的展览药理学活动。然而,人参皂甙 Rh2 的 anticancer 机制是不清楚的。在这研究,我们发现人参皂甙 Rh2 有效地禁止生长并且导致 HL-60 房间的 apoptosis。用 microarray 技术,我们发现了那个肿瘤坏死因素 --(TNF-) 清楚地是起来调整的。而且, anti-TNF- 抗体经由 caspase-8, caspase-9,和 caspase-3 激活的抑制减轻了导致 Rh2 的 HL-60 房间 apoptosis。另外, TNF- 起来规定也在另外的对待 Rh2 的癌症房间线被观察。这些结果证明 TNF- 在人参皂甙起一个关键作用导致 Rh2 的房间 apoptosis。 | Jingjia Huang Kunjian Peng Linghao Wang Bin Wen Lin Zhou Tiao Luo Min Su Jijia Li Zhiyong Luo | 2016 | Acta Biochimica et Biophysica Sinica2016，48，8： | 11 |
| 3 | Lithofacies paleogeography mapping and reservoir prediction in tight sandstone strata: A case study from central Sichuan Basin, China显示文摘Sand-rich tight sandstone reservoirs are potential areas for oil and gas exploration. However, the high ratio of sandstone thickness to that of the strata in the formation poses many challenges and uncertainties to traditional lithofacies paleogeography mapping. Therefore, the prediction of reservoir sweet spots has remained problematic in the field of petroleum exploration. This study provides new insight into resolving this problem, based on the analyses of depositional characteristics of a typical modern sand-rich formation in a shallow braided river delta of the central Sichuan Basin, China. The varieties of sand-rich strata in the braided river delta environment include primary braided channels,secondary distributary channels and the distribution of sediments is controlled by the successive superposed strata deposited in paleogeomorphic valleys. The primary distributary channels have stronger hydrodynamic forces with higher proportions of coarse sand deposits than the secondary distributary channels. Therefore, lithofacies paleogeography mapping is controlled by the geomorphology, valley locations, and the migration of channels. We reconstructed the paleogeomorphology and valley systems that existed prior to the deposition of the Xujiahe Formation. Following this, rock-electro identification model for coarse skeletal sand bodies was constructed based on coring data. The results suggest that skeletal sand bodies in primary distributary channels occur mainly in the valleys and low-lying areas,whereas secondary distributary channels and fine deposits generally occur in the highland areas. The thickness distribution of skeletal sand bodies and lithofacies paleogeography map indicate a positive correlation in primary distributary channels and reservoir thickness. A significant correlation exists between different sedimentary facies and petrophysical properties. In addition, the degree of reservoir development in different sedimentary facies indicates that the mapping method reliably predicts the distribution of sweet spots. The application and understanding of the mapping method provide a reference for exploring tight sandstone reservoirs on a regional basis. | Yuan Zhong Lu Zhou Xiucheng Tan Chengbo Lian Hong Liu Jijia Liao Guang Hu Mingjie Liu Jian Cao | 2017 | Geoscience Frontiers2017，8，5： | 9 |
| 4 | Effects of loading condition on very-high-cycle fatigue behaviour and dominant variable analysis显示文摘The specimens of a high carbon chromium steel were quenched and tempered at 150°C,180°C and 300°C.Such specimens were tested via rotating bending and a push-pull type of axial loading to investigate the influences of loading condition on the behaviour of very-high-cycle fatigue(VHCF).Experimental results show the different influences of inclusion size on the fatigue life for the two loading conditions.Predominant factors and mechanism for the fine-granular-area(FGA)of crack origin were discussed.In addition,a reliability analysis based on a modified Tanaka-Mura model was carried out to evaluate the sensitivity of inclusion size,stress,and KFGA to the life of VHCF crack initiation. | LEI ZhengQiang XIE JiJia SUN ChengQi HONG YouShi | 2014 | Science China(Physics,Mechanics & Astronomy)2014，57，1： | 4 |
| 5 | Transcriptomics-based identification and characterization of 11 CYP450 genes of Panax ginseng responsive to MeJA显示文摘Cytochromes P450 (CYP450s),a superfamily of mono-oxygenases,are essential to generate highly functionalized secondary metabolites in plants and contribute to the diversification of specialized triterpenoid biosynthesis in eudicots.However,screening and identifying the exact CYP450 genes in ginsenoside biosynthesis is extremely challenging due to existence of large quantities of members in CYP450 superfamily.Therefore,to screen the CYP450 genes involved in ginsenoside bio- synthesis,transcriptome dataset of Panax ginseng was created in our previous work using the technique of the next-generation sequencing.On the basis of bioinformatics analysis,16 putative CYP450 genes with significant differential expression were screened from the dataset and submit- ted to GenBank,in which 11 of them have been cloned.Methyl jasmonate (MeJA)was used as an elicitor to analyze the expression profiles of candidate CYP450 genes by quantitative real-time reverse transcription polymerase chain reaction (qRT-PCR).The results of qRT-PCR analysis revealed that the expression of some CYP450 genes were strongly induced by MeJA and showed different transcription levels at different treatment time points.Homology analysis indicated that each putative CYP450 protein of P.ginseng has a conserved domain consisting of E-E-R-F-P-R-G. The CYP450 genes were screened and cloned here to enrich the resources of CYP450 genes,and the results of bioinformatics analysis provided a foundation to further identify the function of CYP450s involved in ginsenoside biosynthesis.Furthermore,this study facilitated the construction of microbial cell factories for increasing the production of ginsenosides by means of metabolic engineering. | Xu Zeng Tiao Luo Jijia Li Gui Li Donghua Zhou Tuo Liu Xian Zou Aparna Pandey Zhiyong Luo | 2018 | Acta Biochimica et Biophysica Sinica2018，50，11： | 2 |
| 6 | The operational seasonal forecasting of summer rainfall in China显示文摘 | Zhang Jijia Chen Xingfang | 1987 | Adv Atmos Sci1987，4，4： | 1 |
| 7 | Selective TBK1/IKKi dual inhibitors with anticancer potency显示文摘 | Jijia Li Jingjia Huang Ji‐Hak Jeong Sun‐Jin Park Rui Wei Jieying Peng Zhiyong Luo Yen Ting Chen Yangbo Feng Jun‐Li Luo | 2014 | Int. J. Cancer2014，，： | 1 |
| 8 | Ginsenoside Rh2 inhibits breast cancer cell growth via ERβ-TNFα pathway显示文摘Ginsenoside Rh2 is one of rare panaxidiols extracted from Panax ginseng and a potential estrogen receptor ligand that exhibits moderate estrogenic activity.However,the effect of Rh2 on growth inhibition and its underlying molecular mechanism in human breast cells are not fully understood.In this study,we tested cell viability by MTT and colony formation assays.Cell growth and cell cycle were determined to investigate the effect of ginsenoside Rh2 by flow cytometry.The expressions of estrogen receptors(ERs),TNFα,and apoptosis-related proteins were detected by qPCR and western blot analysis.The mechanisms of ERαand ERβaction were determined using transfection and inhibitors.Antitumor effect of ginsenoside Rh2 against MCF-7 cells was investigated in xenograft mice.Our results showed that ginsenoside Rh2 induced apoptosis and G1/S phase arrest in MCF-7 cells.Treatment of cells with ginsenoside Rh2 down-regulated protein levels of ERα,and up-regulated mRNA and protein levels of ERβand TNFα.We also found that ginsenoside Rh2-induced TNFαover-expression is through up-regulation of ERβinitiated by ginsenoside Rh2.Furthermore,ginsenoside Rh2 induced MCF-7 cell apoptosis via estrogen receptorβTNFαpathway in vivo.These results demonstrate that ginsenoside Rh2 promotes TNFα-induced apoptosis and G1/S phase arrest via regulation of ERβ. | Kunjian Peng Tiao Luo Jijia Li Jingjia Huang Zizeng Dong Jia Liu Chaoqiong Pi Zizeng Zou Qin Gu Ousheng Liu Jian-Ting Zhang Zhi-Yong Luo | 2022 | Acta Biochimica et Biophysica Sinica2022，54，5： | 1 |
| 9 | The expression of vascular endothelial growth factor in mast cells promotes the neovascularisation of human pterygia显示文摘 | Kun Liang Zhengxuan Jiang Bingying Zhao Jijia Shen Dake Huang Liming Tao | 2012 | British Journal of Ophthalmology2012，，9： | 1 |
| 10 | Microstructure and mechanical properties of aluminum 5083 weldments by gas tungsten arc and gas metal arc welding显示文摘 | Liu Yao Wang Wenjing Xie Jijia | 2012 | Materials Science and Engineering A2012，549，： | 1 |
| 11 | Effects of strength level and loading frequency on very-high-cycle fatigue behavior for a bearing steel显示文摘 | Aiguo Zhao Jijia Xie Chengqi Sun Zhengqiang Lei Youshi Hong | 2011 | International Journal of Fatigue2011，，： | 1 |
| 12 | The expression of vascular endothelial growth factor in mast cells promotes the neovascularisation of human pterygia显示文摘 | Kun Liang Zhengxuan Jiang Bingying Zhao Jijia Shen Dake Huang Liming Tao | 2012 | British Journal of Ophthalmology2012，，9： | 1 |
| 13 | DYNAMIC BUCKLING OF STATICALLY PRELOADED RING-STIFFENED CYLINDRICAL SHELLS UNDER AXIAL FLUID-SOLID IMPACT LOADING显示文摘The Initial Imperfection Amplified Criterion is applied to investigate the geometric nonlineardynamic buckling of statically preloaded ring-stiffened cylindrical shells under axial fluid-solid impact.Tak-ing account of the effects of large deformation and initial geometric imperfection,the governing equations areobtained by the Galerkin method and solved by the Runge-Kutta method.The effects of static preloading(uniform external radial pressure)on the buckling features and the load-carrying ability of ring-stiffened cy-lindrical shells against axial impact are discussed. | Jiang Songqing Li Yongchi Hu Xiuzhang Zheng Jijia | 2000 | Acta Mechanica Solida Sinica2000，13，3： | 1 |
| 14 | Identification and phylogenetic analysis of Vibrio vulnificus isolated from diseased Trachinotus ovatus in cage mariculture显示文摘 | Guifeng Li Dianhui Zhao Lu Huang Jijia Sun Dong Gao Haifang Wang Yongli Tan Lanqing Liang | 2006 | Aquaculture2006，，1： | 1 |
| 15 | Effects of Strength Level and Loading Frequency on Very-High-Cycle Fatigue Be- havior for a Bearing Steel显示文摘 | Zhao Aiguo Xie Jijia Sun Chengqi | 2012 | International Journal of Fatigue2012，38，： | 1 |
| 16 | Prediction of threshold value for FGA formation显示文摘 | Aiguo Zhao Jijia Xie Chengqi Sun Zhengqiang Lei Youshi Hong | 2011 | Materials Science & Engineering A2011，，22： | 1 |
| 17 | Genetic engineering of Streptomyces bingchenggensis to produce milbemycins A3/A4 as main components and eliminate the biosynthesis of nan- ehangmycin显示文摘 | ZHANG Ji AN Jing WANG Jijia | 2013 | Applied Microbiology and Biotechnology2013，97，10： | 1 |
| 18 | Typicality effects in picture-word interferenceparadigm: an evaluation of the response exclusion hypothesis显示文摘 | Yanhong Fang Jijia Zhang Guanhai Yin Senqi Hu & Entao Zhang | 2015 | Scandinavian Journal of Pscyology2015，，3： | 1 |
| 19 | A electro-deposition process for fabrication of biomimetic super-hydrophobic surface and its corrosion resistance on magnesium alloy显示文摘 | Yan Liu Xiaoming Yin Jijia Zhang Sirong Yu Zhiwu Han Luquan Ren | 2014 | Electrochimica Acta2014，，： | 1 |
| 20 | Effects of Strength Level and Loading Frequency on Very-High-Cycle Fatigue Behavior for a Bearing Steel显示文摘 | ZHAO Aiguo XIE Jijia SUN Chengqi | | 0，，： | 1 |
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