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46篇 您的检索式:作者名="Jansen AL"
    题名 作者 年代 出处 被引量
1How to overcome ATP-binding cassette drug efflux transporter-mediated drug resistance?显示文摘P-glycoprotein(ABCB1),multidrug resistance protein-1(ABCC1)and breast cancer resistance protein(ABCG2)belong to the ATP-binding cassette(ABC)superfamily of proteins that play an important physiological role in protection of the body from toxic xenobiotics and endogenous metabolites.Beyond this,these transporters determine the toxicity profile of many drugs,and confer multidrug resistance(MDR)in cancer cells associated with a poor treatment outcome of cancer patients.It has long been hypothesized that inhibition of ABC drug efflux transporters will increase drug accumulation and thereby overcome MDR,but until now no approved inhibitor of these transporters is available in the clinic.In this review we present molecular strategies to overcome this type of drug resistance and discuss for each of these strategies their promising value or indicate underlying reasons for their limited success.Adrian C.Jaramillo Farah Al Saig Jacqueline Cloos Gerrit Jansen Godefridus J.Peters 2018Cancer Drug Resistance2018,1,1:3
2Vertebroplasty versus conservative treatment in acute osteoporotic vertebral compression fractures (Vertos II): an open-label randomised trial显示文摘Caroline AH Klazen Paul NM Lohle Jolanda de Vries Frits H Jansen Alexander V Tielbeek Marion C Blonk Alexander Venmans Willem Jan J van Rooij Marinus C Schoemaker Job R Juttmann Tjoen H Lo Harald JJ Verhaar Yolanda van der Graaf Kaspar J van Everdingen Al 20102010 (9746)2010,,9746:2
3Rheumatoid factor and antibodies to cyclic citnllinated Peptide differentiate rheumatoid arthritis from undifferentiated polyarthritis in patients with early arthritis 显示文摘Jansen AL van der Horst -Bruinsma I van Schaardenburg D 2002J Rheumatol2002,29,10:1
4Long-term (8days) effects of exposure to low concentrations of fluoride on enamelformation in hamster tooth-germ in organ culture in vitro显示文摘 Jansen LL Woltgens JH 1984Arch Oral Biol1984,29,7:1
5Vertebroplasty versus conservative treatment in acute osteoporotic vertebral compression fractures (Vertos II): an open-label randomised trial显示文摘Caroline AH Klazen Paul NM Lohle Jolanda de Vries Frits H Jansen Alexander V Tielbeek Marion C Blonk Alexander Venmans Willem Jan J van Rooij Marinus C Schoemaker Job R Juttmann Tjoen H Lo Harald JJ Verhaar Yolanda van der Graaf Kaspar J van Everdingen Al 2010The Lancet2010,,9746:1
6ll-Substituted ( R )-aporphines: synthesis, pharmacology, and modeling of D2A and 5-HT1A receptor interactions显示文摘HEDBERG M H LINNANEN T JANSEN J M et al 1996J Med Chem1996,39,18:1
7A histological study of the short - term effects of fluoride on enamel and dentine formation in hamster tooth - germs in organ culture in vitro显示文摘Bronckers AL Jansen EL Woltgens JH 1984Arch Oral Biol1984,29,10:1
8Low level of dopmnin- ergie D2 receptor binding in obsessive-compulsive disorder显示文摘Denys D Van Oler Ween N Jansen J et al 2005Biol Payehiatry2005,54,:1
9Beta-defensin-2 protein is a senlm biomarker for disease aetivity in psoriasis and reaches biologically relevant eoneenlralions in lesional skin 显示文摘Jansen PA Rodijk-Ohhuis D Hollox E J el al 2009PI~S One2009,4,3:1
10A histological study of the short-term effects of fluoride on enamel and dentine formation in hamster tooth-germs in organ culture in vitro 显示文摘Bronckers AL Jansen LL Woltgens JH 1984Arch Oral Biol1984,29,10:1
11Pulsed infrared light alters neural activity in rat somatosensory cortex in vivo显示文摘Cayee J M Friedman R M Jansen E D el al 2011NeuroImage2011,57,1:1
12Rheuma- toid factor and antibodies to cyclic citrullinated Peptide differentiate rhemnatoid arthritis from undifferentiated polyarthritis in patients with early arthritis 显示文摘Jansen AL vander Horst-Bruinsma I van Schaardenburg D 2002J Rheumatol2002,29,10:1
13Rheumaroid factor and antibodies to cyclic citrul linated peptide differentiate rheumatoid arthritis from un- differentiated polyarthritis in patients with eary arthritis 显示文摘Jansen AL van der Horst- Bruinsma I van Schaardenburg D 2002J Rheumatol2002,29,10:1
14Brucella endocarditis in prosthetic valves显示文摘Al Dahouk S Schneider T Jansen A 2006Can J Cardiol2006,22,11:1
15Embracing the a Heart: perioperative management of patients undergoing off-pump coronary artery bapass grafting using the octopus tissue stabilizer显示文摘Nierich AP Diephuis J Jansen EWL et al 0,,:1
16Preferential gain photonic-crystal fiber for mode stabilization at high average powers显示文摘T Eidam S Hadrich F Jansen el al 2011Opt Express2011,19,9:1
17A comparative sludy of the apparent total tract digestibility of carbahydrates in Icelandic and Danish Warmblood horses fed two different haylages and a concentrate consist- ing of sugar beet pulp and black oats 显示文摘Jansen R B Br ner C Knudsen K E B el al 2010Archives of Animal Nutrition2010,64,5:1
18CD56+ hematological neoplasms presenting in the skin: a retrospective analysis of 23 new cases and 130 cases from the literature显示文摘Bekkenk MW Jansen PM Meijer CJ el al 2004Ann One- 012004,15,7:1
19Outbreak of NDM - I - produeing Aeinetobacter baumannii in France Janoary to May 2013 显示文摘Decousser J W Jansen C Nordmann P el al 2013Euro Surveill2013,18,20:1
20显示文摘Mies M J M Rebrov E V Jansen J C er al 2007Journal of Ca- talysis2007,247,2:1
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