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| 1 | 面向21世纪的卒中新定义:美国心脏病学会和美国卒中学会声明显示文摘尽管脑血管病有着全球性影响且对其病理生理学的认识有了很多进步,但是'卒中'这一术语在临床实践、临床研究或公共卫生评估中的定义却不一致。传统的定义依据于临床,却没有考虑到科学技术的进步。美国心脏协会(AHA)和美国卒中协会(ASA)卒中分会组织了写作小组,为21世纪卒中新定义撰写专家共识性声明。中枢神经系统(CNS)梗死,指由缺血所导致的脑、脊髓或视网膜的细胞死亡,是基于持续性损害的神经病理学、神经影像学和(或)临床证据。CNS梗死表现为一个临床谱:缺血性卒中特指伴有明显症状的CNS梗死,而静息性梗死根据定义指未引起已知的症状的梗死。卒中也还包括脑出血和蛛网膜下腔出血。新定义的卒中结合了临床和组织学标准,可被用于实践、研究和公共卫生评估。 | 俞羚 董荃 宋叶平 江静雯 李卉 刘亮贤 苏爱萍 李焰生 Sacco RL Kasner SE Broderick JP Caplan LR Connors JJ Culebras A Elkind MS George MG Hamdan AD Higashida RT Hoh BL Janis LS Kase CS Kleindorfer DO Lee JM Moseley ME Peterson ED Turan TN Valderrama AL Vinters HV | 2013 | 神经病学与神经康复学杂志2013，10，2： | 188 |
| 2 | Role of endoscopic ultrasound/SpyScope in diagnosis and treatment of choledocholithiasis in pregnancy显示文摘Cholelithiasis and choledocholithiasis occur frequently in pregnancy and their management can be complicated. Traditional endoscopic retrograde cholangiopancreatography(ERCP)is the first line treatment for choledocholithiasis,but in addition to its baseline risks,fluoroscopy poses an additional radiation risk to the fetus. Endoscopic ultrasound(EUS)is an accurate modality for detecting common bile duct stones,but its role has not been defined in pregnancy.We describe an alternative management strategy to conventional ERCP in a pregnant patient with choledocholithiasis and cholangitis detected using EUS and choledochoscopy. | Mohit Girotra Niraj Jani | 2010 | World Journal of Gastroenterology2010，16，28： | 11 |
| 3 | Dietary and metabolomic determinants of relapse in ulcerative colitis patients: A pilot prospective cohort study显示文摘AIM To identify demographic, clinical, metabolomic, and lifestyle related predictors of relapse in adult ulcerative colitis(UC) patients.METHODS In this prospective pilot study, UC patients in clinical remission were recruited and followed-up at 12 mo to assess a clinical relapse, or not. At baseline information on demographic and clinical parameters was collected. Serum and urine samples were collected for analysis of metabolomic assays using a combined direct infusion/liquid chromatography tandem mass spectrometry and nuclear magnetic resolution spectroscopy. Stool samples were also collected to measure fecal calprotectin(FCP). Dietary assessment was performed using a validated self-administered food frequency questionnaire. RESULTS Twenty patients were included(mean age: 42.7 ± 14.8 years, females: 55%). Seven patients(35%) experienced a clinical relapse during the follow-up period. While 6 patients(66.7%) with normal body weight developed a clinical relapse, 1 UC patient(9.1%) who was overweight/obese relapsed during the follow-up(P = 0.02). At baseline, poultry intake was significantly higher in patients who were still in remission during follow-up(0.9 oz vs 0.2 oz, P = 0.002). Five patients(71.4%) with FCP > 150 μg/g and 2 patients(15.4%) with normal FCP(≤ 150 μg/g) at baseline relapsed during the follow-up(P = 0.02). Interestingly, baseline urinary and serum metabolomic profiling of UC patients with or without clinical relapse within 12 mo showed a significant difference. The most important metabolites that were responsible for this discrimination were trans-aconitate, cystine and acetamide in urine, and 3-hydroxybutyrate, acetoacetate and acetone in serum. CONCLUSION A combination of baseline dietary intake, fecal calprotectin, and metabolomic factors are associated with risk of UC clinical relapse within 12 mo. | Ammar Hassanzadeh Keshtel iFloris F van den Brand Karen L Madsen Rupasri Mandal Rosica ValchevaKaren I Kroeker Beomsoo Han Rhonda C Bell Janis Cole Thomas Hoevers David S Wishart Richard N Fedorak Levinus A Dieleman | 2017 | World Journal of Gastroenterology2017，23，21： | 9 |
| 4 | Paired associated magnetic stimulation promotes neural repair in the rat middle cerebral artery occlusion model of stroke显示文摘Paired associative stimulation has been used in stroke patients as an innovative recovery treatment.However,the mechanisms underlying the therapeutic effectiveness of paired associative stimulation on neurological function remain unclear.In this study,rats were randomly divided into middle cerebral occlusion model(MCAO)and paired associated magnetic stimulation(PAMS)groups.The MCAO rat model was produced by middle cerebral artery embolization.The PAMS group received PAMS on days 3 to 20 post MCAO.The MCAO group received sham stimulation,three times every week.Within 18 days after ischemia,rats were subjected to behavioral experiments—the foot-fault test,the balance beam walking test,and the ladder walking test.Balance ability was improved on days 15 and 17,and the footfault rate was less in their affected limb on day 15 in the PAMS group compared with the MCAO group.Western blot assay showed that the expression levels of brain derived neurotrophic factor,glutamate receptor 2/3,postsynaptic density protein 95 and synapsin-1 were significantly increased in the PAMS group compared with the MCAO group in the ipsilateral sensorimotor cortex on day 21.Resting-state functional magnetic resonance imaging revealed that regional brain activities in the sensorimotor cortex were increased in the ipsilateral hemisphere,but decreased in the contralateral hemisphere on day 20.By finite element simulation,the electric field distribution showed a higher intensity,of approximately 0.4 A/m^2,in the ischemic cortex compared with the contralateral cortex in the template.Together,our findings show that PAMS upregulates neuroplasticity-related proteins,increases regional brain activity,and promotes functional recovery in the affected sensorimotor cortex in the rat MCAO model.The experiments were approved by the Institutional Animal Care and Use Committee of Fudan University,China(approval No.201802173 S)on March 3,2018. | Bei-Yao Gao Cheng-Cheng Sun Guo-Hua Xia Shao-Ting Zhou Ye Zhang Ye-Ran Mao Pei-Le Liu Ya Zheng Dan Zhao Xu-Tong Li Janie Xu Dong-Sheng Xu Yu-Long Bai | 2020 | Neural Regeneration Research2020，15，11： | 8 |
| 5 | 21世纪的卒中新定义:美国心脏协会/美国卒中协会对医疗专业人员的声明显示文摘尽管脑血管病的影响广泛且对其病理生理学的理解已取得一些进展,但“卒中”一词在临床实践、临床研究和公共卫生评价中的定义并不统一。经典的卒中定义主要是临床定义,不能反映科学技术的进步。因此,美国心脏协会卒中委员会/美国卒中协会召集了一个写作组,旨在对21世纪的卒中新定义制定一份专家共识文件。中枢神经系统(centralnervoussystem,CNS)梗死被定义为缺血导致的脑、脊髓或视网膜细胞死亡,并且具有永久性损伤的神经病理学、神经影像学和(或)临床证据。CNS梗死具有一系列临床表现:缺血性卒中特指伴有明显症状的CNS梗死,而无症状梗死则顾名思义不引起明显症状。广义的卒中还包括脑出血和蛛网膜下腔出血。卒中的新定义结合了临床和组织学标准,因此能被融入临床实践、研究和公共卫生评价。 | Ralph L. Sacco Scott E. Kasner Joseph P. Broderick Louis R. Caplan J.J. (Buddy) Connors Antonio Culebras Mitchell S.V. Elkind Mary G. George Allen D. Hamdan Randall T. Higashida Brian L. Hoh L. Scott Janis Carlos S. Kase Dawn O. Kleindorfer Jin-Moo Lee Michael E. Moseley Eric D. Peterson Tanya N. Turan Amy L. Valderrama Harry V. Vinters 王胜男(译) 吴齐恒(译) 邓镇(译) 周晓(译) 袁超(译) 潘速跃(译) | 2014 | 国际脑血管病杂志2014，22，1： | 7 |
| 6 | 超声辅助钼靶检测技术应用于不同乳腺癌风险女性的筛查效果评估显示文摘乳腺密度是影响乳腺癌发生与否的一个重要危险因素,对乳腺致密型妇女仅采用钼靶筛查的难度较大,因此有学者建议将全乳超声检查作为钼靶筛查的辅助手段,以改善乳腺致密型女性的疾病预后,但超声辅助钼靶检查是否可改善乳腺癌的筛查效率目前尚不明确。本研究基于2000年1月至2013年12月的美国两个乳腺癌监测联盟登记的前瞻性观察数据,对仅采用钼靶筛查和采用钼靶+超声筛查的两类人群进行了对比分析;共纳入3386名女性的6081次钼靶+超声筛查结果,并通过1∶5倾向性系数评分匹配了15176名女性的30062次钼靶筛查结果;排除标准为已知患乳腺癌或自述具有乳腺症状的女性;评价指标包括:癌症检出率、间期癌发生率、活检假阳性率、短间隔随访率,以及推荐活检阳性预测值等。 | 李婷媛 乔良(编译) Janie ML Robert FA Brian LS | 2019 | 中华预防医学杂志2019，53，11： | 6 |
| 7 | 胎儿镜引导下激光血管凝固治疗双胎输血综合征后出现双胎间单绒毛膜胎盘血管吻合现象:有肉眼无法发现的微小血管吗?显示文摘Objective: This study was undertaken to detect missed anastomoses on the chorionic surface as well as hidden connections in the depth of the cotyledons in placentas after laser coagulation for twin-to-twin transfusion syndrome (TTTS) and to correlate these findings to clinical outcome. Study design: All cord vessels were injected with dyed barium sulphate. A digital photograph of the chorionic surface angioarchitecture and single-shot digital X- ray (Rx) angiograms were made. The presence and diameter of any missed anastomoses on the chorionic surface and of any hidden angiographic connections were determined. Results: Fifty placentas were analyzed,7 of double intrauterine fetal death (IUFD) and 43 of double survivors. In 9 of 43 (21% ) cases with double survival and in all 7 cases of double IUFD, missed anastomoses were identified that should have been ablated by laser coagulation (P < .001). There appeared to be a correlation between the type and diameter of missed anastomoses on the chorionic surface and the clinical outcome. Placentas with missed large arteriovenous/venoarterial anastomoses (AV/VA) (N = 8) were from cases with recurrent TTTS or double IUFD (unless compensated by a large arterioarterial anastomosis [AA]). Next, missed small AV/VA (N = 4) without AA resulted in isolated (ie, without TTTS) discordant hemoglobin levels requiring intrauterine transfusion. Finally, when there were no missed anastomoses (N = 34), TTTS had resolved in all cases and outcome was good, although 1 case had discordant hemoglobin values treated with a single intrauterine transfusion and 4 others had discordant hemoglobin at birth. On Rx angiography, potential hidden connections were present, all but 1 case. Conclusion: Coagulation of all anastomoses visible on the chorionic surface seems adequate to treat TTTS. However, hidden connections in the depth of the cotyledon could not be excluded and may be involved in lesser degrees of intertwin transfusion. | Lewi L. Jani J. Cannie M. 朱国栋 | 2006 | 世界核心医学期刊文摘(妇产科学分册)2006，0，8： | 6 |
| 8 | Inhibition of methionine adenosyltransferase II induces FasL expression, Fas-DISC formation and caspase-8-dependent apoptotic death in T leukemic cells显示文摘蛋氨酸 adenosyltransferase II (地席 II ) 是在细胞的新陈代谢的关键酶并且从 L 蛋氨酸和 ATP 催化 S-adenosylmethionine (一样) 的形成。正常休息 T 淋巴细胞举办最小的地席 II 活动,而白血病的房间显著地显示出的激活的增殖的 T 淋巴细胞和转变 T 提高了地席 II 活动。这个工作被执行在白血病的 T 房间的幸存检验地席 II 活动和一样的生合成的角色。在一样的层次的地席 II 和结果的减少的抑制提高了 FasL mRNA 和蛋白质的表示,并且导致了圆盘(导致发信号的建筑群的死亡) 有 FADD (联系船边交货的死亡域) 和 procaspase-8 招募的形成,以及 caspase-8 激活的伴随物增加和在 c 扭动的减少铺平。开始船边交货的发信号由地席 II 抑制导致了被观察经由出价劈开连接到 mitochondrial 小径并且最终在这些房间导致增加的 caspase-3 激活和 DNA 破碎。而且,堵住地席 2A mRNA 表示,它编码地席 II 的催化子单元,用一条小介入的 RNA 途径提高了 FasL 表示和房间死亡,验证在 T 白血病的房间的幸存的地席 II 活动的必要性质。 | Tanvi S Jani Leila Gobejishvili Prachi T Hote Aditya S Barve Swati Joshi-Barve Giorgi Kharebava Jill Suttles Theresa Chen Craig J McClain Shirish Barve | 2009 | Cell Research2009，19，3： | 5 |
| 9 | Simple and Rapid Synthesis ofα-Fe_(2)O_(3)Nanowires Under Ambient Conditions显示文摘We propose a simple method for the efficient and rapid synthesis of one-dimensional hematite(α-Fe_(2)O_(3))nanostructures based on electrical resistive heating of iron wire under ambient conditions.Typically,1-5μm longα-Fe_(2)O_(3)nanowires were synthesized on a time scale of seconds at temperatures of around 700℃.The morphology,structure,and mechanism of formation of the nanowires were studied by scanning and transmission electron microscopies,energy dispersive X-ray spectroscopy,X-ray photoelectron spectroscopy,and Raman techniques.A nanowire growth mechanism based on diffusion of iron ions to the surface through grain boundaries and to the growing wire tip through stacking fault defects and due to surface diffusion is proposed. | Albert G.Nasibulin Simas Rackauskas Hua Jiang Ying Tian Prasantha Reddy Mudimela Sergey D.Shandakov Larisa.Nasibulina Jani Sainio Esko I.Kauppinen | 2009 | Nano Research2009，2，5： | 4 |
| 10 | 制鞋工业中用于抑菌处理的甘油一酸酯(英文)显示文摘以甘油与不同偶数脂肪酸为原料合成了一系列甘油 酸酯(MAGS):甘油一辛酸酯(MAGC8∶0),甘油一癸酸酯(MAGC10∶0),甘油 2 乙基乙酸单酯(MAG2Eth C6∶0)和甘油一月桂酸酯(MAGC12∶0),测定其抑菌效果。这些材料以乙醇溶液的形式应用于衬里材料上。酵母菌(白色念菌和近平滑假丝酵母)的实验证明这两种酵母菌对MAGC8∶0和MAGC10∶0敏感。在100~150mg/L的浓度范围内MAGC8∶0和MAGC10∶0抑制微生物生长。纤维霉菌特别受到MAGC8∶0(100mg/L)溶液的抑制。当这一浓度的MAGC8∶0溶液应用于被测材料时,黑曲霉、点状毛霉、赭绿青霉具有抵抗性。实验证明,各种MAGS对不同种类可造成霉菌病的真菌微生物的防霉效果不同。 | Rahula Janis Jana Bobalova Jiri Krejci Jitka Homolkova Helena Velichova | 2004 | 皮革科学与工程2004，14，6： | 3 |
| 11 | Service recovery: a framework and empirical investigation显示文摘 | Janis L Miller Christopher W Craighead Kirk R Karwan | 2000 | Journal of Operations Management2000，，4： | 3 |
| 12 | 澳洲坚果九个不同品种品质考察研究显示文摘商业型澳洲坚果(Macadamia Nut),从商品角度衡量其经济价值的高低的重要生物学特征之一,是种仁质量。为了筛选澳洲坚果的优质良种推广应用于生产,美国夏威夷农业研究中心(H-AES),从本世纪80年代就布置了9个不同品种澳洲坚果的种质考察试验,并一直坚持到现在,其研究内容有:带壳鲜种子重量百分比、干种仁重量百分比,又叫出仁率、优等种仁百分比、种仁等级、优等种仁还原率、每磅种子粒数、单粒种子均重、单粒种仁均重,畸形种仁及虫害为害等。通过全面比较鉴别,本试验的9个不同的澳洲坚果品种,可划分为优秀、良好及一般三种类型。本文所用的研究资料是1987—1990年的试验报告数据。 | 晏敏华 P.J.ITO Janis Iyo | 1992 | 广西热作科技1992，，4： | 3 |
| 13 | Early Repolarization: Electrocardiographic Phenotypes Associated With Favorable Long-Term Outcome显示文摘 | Jani T. Tikkanen M. Juhani Junttila Olli Anttonen Aapo L. Aro Samuli Luttinen Tuomas Kerola Solomon J. Sager Harri A. Rissanen Robert J. Myerburg Antti Reunanen Heikki V. Huikuri | 2011 | Circulation2011，，23： | 3 |
| 14 | Cytokine mucosal expression in ulcerative colitis, the relationship between cytokine release and disease activity显示文摘 | Daniel S. Pearl Krina Shah Mark A. Whittaker Harriet Nitch-Smith James F. Brown Janis K. Shute Timothy M. Trebble | 2012 | Journal of Crohn’s and Colitis2012，，： | 3 |
| 15 | An Updated Definition of Stroke for the 21st Century: A Statement for Healthcare Professionals From the American Heart Association/American Stroke Association显示文摘 | Ralph L. Sacco Scott E. Kasner Joseph P. Broderick Louis R. Caplan J.J. (Buddy) Connors Antonio Culebras Mitchell S.V. Elkind Mary G. George Allen D. Hamdan Randall T. Higashida Brian L. Hoh L. Scott Janis Carlos S. Kase Dawn O. Kleindorfer Jin-Moo Lee Mi | 2013 | Stroke2013，，7： | 3 |
| 16 | Autoimmune pancreatitis and cholangitis显示文摘Autoimmune pancreatitis(AIP) is part of a systemic fibrosclerotic process characterized by lymphoplasmacytic infiltrate with immunoglobulin G subtype-4(Ig G4) positive cells. It characteristically presents with biliary obstruction due to mass-like swelling of the pancreas. Frequently AIP is accompanied by extra-pancreaticmanifestations including retroperitoneal fibrosis, thyroid disease, and salivary gland involvement. Auto-antibodies, hypergammaglobulemia, and prompt resolution of pancreatic and extrapancreatic findings with steroids signify its autoimmune nature. Refractory cases are responsive to immunomodulators and rituximab. Involvement of the biliary tree, termed IgG 4 associated cholangiopathy, mimics primary sclerosing cholangitis and is challenging to manage. High IgG 4 levels and swelling of the pancreas with a diminutive pancreatic duct are suggestive of autoimmune pancreatitis. Given similarities in presentation but radical differences in management and outcome, differentiation from pancreatic malignancy is of paramount importance. There is controversy regarding the optimal diagnostic criterion and steroid trials to make the diagnosis. Additionally, the retroperitoneal location of the pancreas and requirement for histologic sampling, makes tissue acquisition challenging. Recently, a second type of autoimmune pancreatitis has been recognized with similar clinical presentation and steroid response though different histology, serologic, and extrapancreatic findings. | Niraj Jani James Buxbaum | 2015 | World Journal of Gastrointestinal Pharmacology and Therapeutics2015，6，4： | 2 |
| 17 | Electromagnetic induction mapping at varied soil moisture reveals field-scale soil textural patterns and gravel lenses显示文摘Knowledge of the spatial distribution of soil textural properties is important for determining soil moisture storage and soil hydraulic transport properties.Capturing field heterogeneity without exhaustive sampling and costly sample analysis is difficult. Our objective was to employ electromagnetic induction(EMI) mapping in low apparent electrical conductivity(EC_a) soils at varying soil water contents to capture time invariant properties such as soil texture. Georeferenced EC_ameasurements were taken using a ground conductivity meter on six different days where volumetric water content(θ_v) varied from 0.11 to 0.23. The 50 m × 50 m field included a subsurface gravelly patch in an otherwise homogeneous silt-loam alluvial soil.Ordinary block kriging predicted EC_aat unsampled areas to produce 1-m resolution maps. Temporal stability analysis was used to divide the field into three distinct EC_a regions. Subsequent ground-truthing confirmed the lowest conductivity region correlated with coarse textured soil parent materials associated with a former high-energy alluvial depositional area. Combining maps using temporal stability analysis gives the clearest image of the textural difference. These maps could be informative for modeling,experimental design, sensor placement and targeted zone management strategies in soil science, ecology, hydrology,and agricultural applications. | Hiruy ABDU David A.ROBINSON Janis BOETTINGER Scott B.JONES | 2017 | Frontiers of Agricultural Science and Engineering2017，4，2： | 2 |
| 18 | Epidemiology, Clinical Features, High-Risk Factors, and Outcome of Acute Large Bowel Ischemia显示文摘 | George F. Longstreth Janis F. Yao | 2009 | Clinical Gastroenterology and Hepatology2009，，10： | 2 |
| 19 | 《语言的功能取向》述介显示文摘当代语言学中的功能主义兴起于20世纪60年代末,其根本出发点是从语言结构之外寻找解释语言形成和结构规律的因素,并强调基于语言运用的研究模式。在过去的半个世纪中,功能主义学说为一大批学者所青睐,不仅在语言学理论上有所建树,而且还对社会语言学、语言教学、语言习得、 | Shannon T. Bischoff Carmen Jany 丁健 | 2016 | 当代语言学2016，18，3： | 2 |
| 20 | A Prospective, Randomized, Double-Blind, Placebo-Controlled Trial of Retinol Palmitate (Vitamin A) for Symptomatic Chronic Radiation Proctopathy显示文摘 | Eli D. Ehrenpreis Ashesh Jani Josh Levitsky Joseph Ahn John Hong | 2005 | Diseases of the Colon & Rectum2005，，1： | 2 |
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