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| 1 | 布南色林治疗精神分裂症的临床应用中日专家建议显示文摘第二代(非典型)抗精神病药布南色林对多巴胺D_(2)、D_(3)受体和5-HT_(2A)受体均有较高亲和力,而对肾上腺素α_(1)、5-HT_(2c)、组胺H_(1)、毒蕈碱M_(1)和M_(3)等受体亲和力较低。多项短期和长期临床研究显示:该药对精神分裂症的阳性症状、阴性症状均有较好疗效,并改善患者的部分认知症状和社会功能。本文在循证证据和多位中日专家临床用药经验基础上撰写,希望为临床精神科医生提供用药参考,帮助精神分裂症患者早日康复,回归社会。 | 于欣 司天梅 陆峥 石川 IYO Masaomi IWATA Nakao UENO Takefumi INADA Ken HORI Hikaru | 2021 | 中国心理卫生杂志2021，35，9： | 7 |
| 2 | Memory consolidation during sleep and adult hippocampal neurogenesis显示文摘In anticipation of the massive burden of neurodegenerative disease within super-aged societies, great efforts have been made to utilize neural stem and progenitor cells for regenerative medicine. The capacity of intrinsic neural stem and progenitor cells to regenerate damaged brain tissue remains unclear, due in part to the lack of knowledge about how these newly born neurons integrate into functional circuitry. As sizable integration of adult-born neurons naturally occurs in the dentate gyrus region of the hippocampus, clarifying the mechanisms of this process could provide insights for applying neural stem and progenitor cells in clinical settings. There is convincing evidence of functional correlations between adult-born neurons and memory consolidation and sleep; therefore, we describe some new advances that were left untouched in our recent review. | Iyo Koyanagi Katherine G.Akers Pablo Vergara Sakthivel Srinivasan Takeshi Sakurai Masanori Sakaguchi | 2019 | Neural Regeneration Research2019，14，1： | 4 |
| 3 | 澳洲坚果九个不同品种品质考察研究显示文摘商业型澳洲坚果(Macadamia Nut),从商品角度衡量其经济价值的高低的重要生物学特征之一,是种仁质量。为了筛选澳洲坚果的优质良种推广应用于生产,美国夏威夷农业研究中心(H-AES),从本世纪80年代就布置了9个不同品种澳洲坚果的种质考察试验,并一直坚持到现在,其研究内容有:带壳鲜种子重量百分比、干种仁重量百分比,又叫出仁率、优等种仁百分比、种仁等级、优等种仁还原率、每磅种子粒数、单粒种子均重、单粒种仁均重,畸形种仁及虫害为害等。通过全面比较鉴别,本试验的9个不同的澳洲坚果品种,可划分为优秀、良好及一般三种类型。本文所用的研究资料是1987—1990年的试验报告数据。 | 晏敏华 P.J.ITO Janis Iyo | 1992 | 广西热作科技1992，，4： | 3 |
| 4 | Fluvoxamine as a sigma--1 receptor agonist improved cognitive impairments in a patient with schizophrenia 显示文摘 | Iyo M Shirayama Y Watanabe H | 2008 | Prog Neuropsychopharmacol Biol Psychiatry2008，32，4： | 1 |
| 5 | Relationship between crystal structure and superconductivity in iron-based superconduc- tor显示文摘 | Lee C H Kihou K Iyo A | 2012 | Solid State Common2012，152，2： | 1 |
| 6 | siRNAs generated by recombinant human Dicer induce specific and significant but target siteindependent gene silencing in human cells显示文摘 | Kawasaki H Suyama E Iyo M | 2003 | Nucleic Acids Res2003，31，： | 1 |
| 7 | Measurement of acetylcholinesterase by positron emission tomography in the brains of healthy controls and patients with Alzheimer's disease显示文摘 | Iyo M Namba H Fukushi K | 1997 | Lancet1997，349，： | 1 |
| 8 | Fluvoxamine as a sigma-1 receptor agonist improved cognitive impairments in a patient with schizophrenia 显示文摘 | Iyo M Shirayama Y Watanabe H | 2008 | Prog Neuropsy- chopharmacol Biol Psychiatry2008，32，4： | 1 |
| 9 | Tissue distribution of P-glycoprotein encoded by a multidrug-resistant gene as revealed by a mono-clonal antibody,MRK16显示文摘 | Sugawara Isamu Kataoka Iyo | 1988 | Cancer Res1988，48，7： | 1 |
| 10 | Agmatine protects against cell damage induced by NMDA and glutamate in cultured hippocampal neurons 显示文摘 | WANG Wei-ping Iyo AH Miguel-Hidalgo J | 2006 | Mol Brain Res2006，1084，1： | 1 |
| 11 | Increased midkine levels in sera from patients with Alzheimer’s disease显示文摘 | Ragaa H.M. Salama Hisako Muramatsu Eiji Shimizu Kenji Hashimoto Shintaro Ohgake Hiroyuki Watanabe Naoya Komatsu Naoe Okamura Kaori Koike Naoyuki Shinoda Shin-ichi Okada Masaomi Iyo Takashi Muramatsu | 2005 | Progress in Neuropsychopharmacology & Biological Psychiatry2005，，4： | 1 |
| 12 | Critical role of brain-derived neurotrophic factor in mood disorders显示文摘 | Hashimoto K Shimizu E Iyo M | 2004 | Brain Res Brain Res Rev2004，45，2： | 1 |
| 13 | A cold-active glucanase from the ruminal bacterium Fibrobacter succinogenes S85 显示文摘 | Iyo A H Forsberg C W | 1999 | Appl Environ Microbiol1999，65，： | 1 |
| 14 | Tropisetron improves deficient inhibitory auditory processing in DBA/2 mice: role of α7 nicotinic acetylcholine receptors显示文摘 | HASHIMOTO K IYO M FREEDMAN R | 2005 | Psychopharmacology(Berl)2005，183，： | 1 |
| 15 | Effect of multiplicative scatter correction on wavelength selection for near infrared calibration to determine fat content in raw milk显示文摘 | Chen J Y Iyo C Teradab F J | 2002 | Journal of Near Infrared Spectroscopy2002，10，4： | 1 |
| 16 | siRNAs generated by re-combinant human Dicer induce specific and significant but targetsite - independent gene silencing in human cells 显示文摘 | Kawasaki H Suyama E Iyo M | 2003 | NucleicAcids Res2003，31，3： | 1 |
| 17 | Effect of intragastric ammonia on gastrin, somatostatin and somatostatin,recep- tor subtype 2 positive-cells in rat antral mucasa显示文摘 | Iyo T Kaneko H Konagaya T | 1999 | Life Sci1999，64，26： | 1 |
| 18 | Critical role of brain-derived neurotrophic factor in mood disorders显示文摘 | Shimizu E Iyo M | 2004 | Brain Res Rev2004，45，2： | 1 |
| 19 | Reduced phosphorylation of the mTOR signaling pathway compo- nents in the amygdala of rats exposed to chronic stress 显示文摘 | Chandran A Iyo A H Jernigan C S | 2013 | Prog Neuropsychopharmacol Biol Psychiatry2013，40，： | 1 |
| 20 | Methamphetamine-related psychiatric synmotoms and reduced brain dopamine transportersstudied with PET 显示文摘 | Sekine Y Iyo M Ouchi Y | 2001 | Am J Psychiatry2001，158，8： | 1 |
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