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| 1 | Neutrophil engagement and septic challenge in acute experimental pancreatitis in rats显示文摘AIM: To investigate the influence of neutrophil adhesion molecule blockade with monoclonal antibody (MoAb CD11b) and E. coli lipopolysaccharide (LPS)administration on experimental acute pancreatitis (AP).METHODS: AP was induced by four ip injections of cerulein (Cn) at 1-h intervals. MoAb CD 11b and LPS were administered at the beginning of the experiment.RESULTS: The neutrophil count and chemiluminescence were diminished at the beginning of AP. The oxidative stress parameters were found within the pancreatic gland. MoAb CD 11b used for AP resulted in a significant reduction of pancreatic infiltration and pancreatitis oxidative stress parameters. Serum interleukin-6 (IL-6)was not detected in AP animals, whereas high serum IL-6 concentration was noted only in animals receiving LPS.CONCLUSION: Neutrophils are involved in pancreatic damage in the early stage of AP. Neutrophil infiltration reduction protects the pancreatic gland from destruction during AP. LPS does not change the early course of Cn pancreatitis in rats. | Stanisiaw Ha Marek Dobosz Jan J Kaczor Robert Rzepko Ewa Aleksandrowicz-Wrona Zdzislaw Wajda Zbigniew ledzi■ski Jacek Krajewski | 2005 | World Journal of Gastroenterology2005，11，41： | 7 |
| 2 | 固定低剂量三联抗高血压药物与常规治疗对斯里兰卡轻度至中度高血压患者血压控制的疗效差异:一项随机临床试验显示文摘控制不良的高血压是全球领先的公共卫生问题,需要新的治疗策略。该研究评估低剂量三联抗高血压药物治疗是否能达到比常规治疗更好的血压控制。研究者纳入2016年2月至2017年5月在斯里兰卡11所城市医院诊所就诊的需要开始抗高血压治疗(未治疗的患者)或接受单药治疗的患者,进行低剂量三联降压与常规治疗比较的随机、开放性试验,随访至2017年10月。 | Web-ster R Salam A de Silva HA Selak V Stepien S Rajapakse S Amarasekara S Amarasena N Billot L de Silva AP Fernando M Guggilla R Jan S Jayawardena J Maulik PK Mendis S Munasinghe J Naik N Prabhakaran D Ranasinghe G Thom S Tisserra N Senaratne V Wijekoon S Wijeyasingam S Rodgers A Patel A 刘莉 叶鹏 | 2018 | 中华高血压杂志2018，26，12： | 7 |
| 3 | 多器官床旁即时超声在新型冠状病毒肺炎中的应用:国际专家共识显示文摘新型冠状病毒肺炎(简称新冠肺炎,COVID-19)自首次报道以来,已造成全球超一亿人感染,给各国的公共卫生体系造成了巨大威胁。新冠肺炎的临床表现以呼吸系统体征和症状为主,80%的患者症状轻微,约5%为危重症患者,常表现为急性呼吸窘迫综合征(ARDS)。前期,由于缺乏相关研究,面对日益紧迫的临床困境,医务人员不得不借鉴采取一些经验性措施以应对疫情。 | 王臻(译) Arif Hussain Gabriele Via Lawrence Melniker Alberto Goffi Guido Tavazzi Luca Neri Tomas Villen Richard Hoppmann Francesco Mojoli Vicki Noble Laurent Zieleskiewicz Pablo Blanco Irene W.Y.Ma Mahathar Abd.Wahab Abdulmohsen Alsaawi Majid AI Salamah Martin Balik Diego Barca Karim Bendjelid Belaid Bouhemad Pablo Bravo-Figueroa Raoul Breitkreutz Juan Calderon Jim Connolly Roberto Copetti Francesco Corradi Anthony J.Dean AndréDenault Deepak Govil Carmela Graci Young-Rock Ha Laura Hurtado Toru Kameda Michael Lanspa Christian B Laursen Francis Lee Rachel Liu Massimiliano Meineri Miguel Montorfano Peiman Nazerian Bret P.Nelson Aleksandar N.Neskovic Ramon Nogue Adi Osman JoséPazeli Elmo Pereira-Junior Tomislav Petrovic Emanuele Pivetta Jan Poelaert Susanna Price Gregor Prosen Shalim Rodriguez Philippe Rola Colin Royse Yale Tung Chen Mike Wells Adrian Wong Wang Xiaoting Wang Zhen Yaseen Arabi | 2021 | 中国呼吸与危重监护杂志2021，20，2： | 5 |
| 4 | C(-260)T Polymorphism in the promoter of the CD14 monocyte receptor gene as a risk factor for myocardial infarction显示文摘 | Jaros lay A Hubacek Jan Pit ha | 1999 | Circulation1999，99，28： | 1 |
| 5 | C(-260)T Polymorphism in the promoter of the CD14 monocyte receptor gene as a risk factor for myocardial infarction显示文摘 | Jaroslav A Hubacek Jan Pit ha | 1999 | Circulation1999，99，28： | 1 |
| 6 | Splenic metastasis from adenocarcinoma of the prostate 显示文摘 | Naseem MS Jan HA Britton KE | 1998 | Br J Urol1998，82，4： | 1 |
| 7 | Novel method for localization of common carotid artery transverse section in ultrasound images using modified Viola-Jones detector显示文摘 | Kamil ?íha Jan Ma?ek Radim Burget Radek Bene? Eva Závodná | 2013 | Ultrasound in Medicine & Biology2013，，： | 1 |
| 8 | C(-260)[right arrow]T Polymorphism in the Promoter of the CD14 Monocyte Receptor Gene as a Risk Factor for Myocardial Infarction显示文摘 | Jaroslav A. Hubacek Jan Pit’ha Zdena Skodova Vladimir Stanek Rudolf Poledne | 1999 | Circulation1999，，25： | 1 |
| 9 | 显示文摘 | Elizabeth DE Jan AM Michael HA | 2000 | Crit Care Med2000，28，2： | 1 |
| 10 | Bone Marrow–Derived Mesenchymal Stem Cell Transplantation for Chronic Spinal Cord Injury in Rats: Comparative Study Between Intralesional and Intravenous Transplantation显示文摘 | Jang-Woon Kim Kee-Yong Ha Jan Noel Molon Young-Hoon Kim | 2013 | Spine2013，，17： | 1 |
| 11 | Increasing Incidence and Continued Dismal Outcome of Primary Central Nervous System Lymphoma in Norway 1989-2003显示文摘 | Ingfrid SH Bard KK Jan HA | | 0，，08： | 1 |
| 12 | PEANUT SKIN ANTIOXIDANTS 显示文摘 | Hoang Van Ha Pokomy Jan Sakurai Hidetoshi | 2007 | Journal of Food Lipids2007，14，3： | 1 |
| 13 | A procedural footprint enhancement of global topographic surface with multiple levels of detail显示文摘Virtual globes are technologies for visual navigation through a threedimensional,multi-resolution model of the entire planet.Data representations used in virtual globes,however,lack geometric flexibility at high-resolution levels of the planet-wide terrain surface.This is a problem especially if boundaries between individual geospatial features and the terrain are important.A novel integration of individual polygonal boundaries with a specific multi-resolution representation of the planet-wide terrain is developed in this article.In the preparation stage,the integration relies on an original simplification algorithm applied to the polygonal boundaries between geospatial features and the terrain.Its output is a multiple level-of-detail(LOD)geometry,which can be combined with a known multi-LOD representation of the terrain that uses run-time triangulation.This data representation is suitable for storage in existing database systems,avoids any data redundancy across LODs,and is even independent of the subdivision schema that partitions the planet’s surface for the sake of dealing with LODs.At runtime,a novel reconstruction algorithm stitches geometric parts from different LODs together in a manner that augments the multi-LOD representation of the terrain.Within a certain proximity range from a given position,the method reconstructs a scene that preserves topological relations between the boundaries of geospatial features with the terrain.The method also guarantees that certain nearest proximity to the given position consists of the best geometries that correspond to the original datasets.Such properties of the method close up the gap between a mere exploratory visualization of static,pre-generated models and the models supporting geospatial analysis,which is deemed crucial for applications in Geographic Information Systems,Building Information Modelling and other software industries.A prototype implementation and experiment results that prove this method are also presented. | Lukáš Brůha Jan Kolář | 2020 | International Journal of Digital Earth2020，13，4： | 0 |
| 14 | In vitro Cyto and Blood Compatibility of Titanium Containing Diamond-Like Carbon Prepared by Hybrid Sputtering Method显示文摘In recent years,diamond-like carbon films (DLC) have been given more attention in research in the biomedical industry due to their potential application as surface coating on biomedical materials such as metals and polymer substrates.There are many ways to prepare metal containing DLC films deposited on polymeric film substrates,such as coatings from car-bonaceous precursors and some means that incorporate other elements.In this study,we in-vestigated both the surface and biocompatible properties of titanium containing DLC (Ti-DLC) films.The Ti-DLC films were prepared on the surface of poly (ethylene terephthalate) (PET) film as a function of the deposition power level using reactive sputtering technique.The films' hydrophilicity was studied by contact angle and surface energy tests.Their surface morphology was studied by scanning electron microscopy (SEM) and atomic force microscopy (AFM).Their elemental chemical composition was analyzed using energy dispersive X-spectra (EDX) and X-ray photoelectron spectroscopy (XPS).Their blood and cell compatibility was studied by in vitro tests,including tests on platelet adhesion,thrombus formation,whole blood clotting time and osteoblast cell compatibility.Significant changes in the morphological and chemical composition of the Ti-DLC films were observed and found to be a function of the deposition level.These morphological and chemical changes reduced the interfacial tension between Ti-DLC and blood proteins as well as resisted the adhesion and activation of platelets on the surface of the Ti-DLC films.The cell compatibility results exhibited significant growth of osteoblast cells on the surface of Ti incorporated DLC film compared with that of DLC film surface. | Krishnasamy NAVANEETHA PANDIYARAJ Jan HEEG Andreas LAMPKA Fabian JUNGE Torsten BARFELS Marion WIENECKE Young Ha RHEE Hyoung Woo KIM | 2012 | Plasma Science and Technology2012，14，9： | 0 |
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