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| 1 | Influence of cardiac nerve status on cardiovascular regulation and cardioprotection显示文摘Neural elements of the intrinsic cardiac nervous system transduce sensory inputs from the heart, blood vessels and other organs to ensure adequate cardiac function on a beat-to-beat basis. This inter-organ crosstalk is critical for normal function of the heart and other organs; derangements within the nervous system hierarchy contribute to pathogenesis of organ dysfunction. The role of intact cardiac nerves in development of, as well as protection against, ischemic injury is of current interest since it may involve recruitment of intrinsic cardiac ganglia. For instance, ischemic conditioning, a novel protection strategy against organ injury, and in particular remote conditioning, is likely mediated by activation of neural pathways or by endogenous cytoprotective bloodborne substances that stimulate different signalling pathways. This discovery reinforces the concept that inter-organ communication, and maintenance thereof, is key. As such, greater understanding of mechanisms and elucidation of treatment strategies is imperative to improve clinical outcomes particularly in patients with comorbidities. For instance, autonomic imbalance between sympathetic and parasympathetic nervous system regulation can initiate cardiovascular autonomic neuropathy that compromises cardiac stability and function. Neuromodulation therapies that directly target the intrinsic cardiac nervous system or other elements of the nervous system hierarchy are currently being investigated for treatment of different maladies in animal and human studies. | John G Kingma Denys Simard Jacques R Rouleau | 2017 | World Journal of Cardiology2017，9，6： | 6 |
| 2 | Coronary artery disease in congenital single coronary artery in adults:A Dutch case series显示文摘AIM:To assess the current diagnostic and therapeutic management and the clinical implications of congenital single coronary artery(SCA) in adults.METHODS:We identified 15 patients with a SCA detected from four Dutch angiography centers in the period between 2010 and 2013.Symptomatic patients who underwent routine diagnostic coronary angiography(CAG) for suspected coronary artery disease and who incidentally were found to have isolated SCA were analyzed.RESULTS:Fifteen(7 females) with a mean age of 58.5 ± 13.78 years(range 43-86) had a SCA.ConventionalCAG demonstrated congenital isolated SCA originating as a single ostium from the right sinus of Valsalva in 6 patients and originating from the left in 9 patients.Minimal to moderate coronary atherosclerotic changes were found in 4,and severe stenotic lesions in another 4 patients.Seven patients were free of coronary atherosclerosis.Runs of non-sustained ventricular tachycardia were documented in 2 patients,one of whom demonstrated transmural ischemic changes on presentation.Myocardial perfusion scintigraphic evidence of transmural myocardial ischemia was found in 1 patient due to kinking and squeezing of the SCA with an interarterial course between the aorta and pulmonary artery.Multi-slice computed tomography(MSCT) was helpful to delineate the course of the anomalous artery relative to the aorta and pulmonary artery.Percutaneous coronary intervention was successfully performed in 3 patients.Eight patients were managed medically.Arterial bypass graft was performed in 4 patients with the squeezed SCA.CONCLUSION:SCA may be associated with transient transmural myocardial ischemia and aborted sudden death in the absence of coronary atherosclerosis.The availability and sophistication of MSCT facilitates the delineation of the course of a SCA.We present a Dutch case series and review of the literature. | Salah AM Said Willem G de Voogt Suat Bulut Jacques Han Peter Polak Rogier LG Nijhuis Jeroen W op den Akker Andries Slootweg | 2014 | World Journal of Cardiology2014，6，4： | 3 |
| 3 | Pulse pressure and aortic pulse wave are markers of cardiovascular risk in hypertensive populations显示文摘 | Roland Asmar Annie Rudnichi Jacques Blacher Gérard M London Michel E Safar | 2001 | American Journal of Hypertension2001，，2： | 3 |
| 4 | Feelings of Anxiety and Symptoms of Depression in Community-Living Older Persons Who Avoid Activity for Fear of Falling显示文摘 | Jolanda C. M. van Haastregt G A. Rixt Zijlstra Erik van Rossum Jacques Th. M. van Eijk Gertrudis I. J. M. Kempen | 2008 | American Journal of Geriatric Psychiatry2008，，3： | 2 |
| 5 | The causes of land-use and land-cover change: moving beyond the myths显示文摘 | Eric F. Lambin B.L. Turner Helmut J. Geist Samuel B. Agbola Arild Angelsen John W. Bruce Oliver T. Coomes Rodolfo Dirzo Günther Fischer Carl Folke P.S. George Katherine Homewood Jacques Imbernon Rik Leemans Xiubin Li Emilio F. Moran Michael Mortimore P.S. | 2001 | Global Environmental Change2001，，4： | 2 |
| 6 | Application of a new 2D time-domain full-waveform inversion scheme to crosshole radar data显示文摘 | Jacques R Ernst Alan G Green Hansruedi Maurer | 2007 | Geophysics2007，72，5： | 1 |
| 7 | Bioconversion of a L-carnitine precursor in a one-or two-phase system 显示文摘 | Bare G Jacques P Hubert J B | 1991 | Appl Biochem Biotechnol1991，2829，： | 1 |
| 8 | Generation of infrared imagery from an aviation synthetic vision database 显示文摘 | MAXIMEE BONJEAN JACQUES G | 2005 | SPIE2005，5802，： | 1 |
| 9 | Interactions of Haemophilus parasuis and its LOS with porcine brain microvascular endothelial cells显示文摘 | Bouchet B Vanier G Jacques M | 2008 | Vet Res2008，39，5： | 1 |
| 10 | Use of a new cardiac pacing mode designed to eliminate unnecessary ventricular pacing 显示文摘 | Gerd F Daniel G Jacques V | 2006 | Europace2006，8，： | 1 |
| 11 | Long quadrilinear CCD sensors equipped with long linear filters-Characteristics and performances for the multispectral channel of earth observing systems显示文摘 | HERVE G JACQUES L ISABELLE L | | 0，，： | 1 |
| 12 | The effect of fo-lic acid fortification on plasma folate and total homocysteine concen-trations 显示文摘 | JACQUES P F SELHUB J BOSTOM A G | 1999 | N Engl J Med1999，340，19： | 1 |
| 13 | Symptomatic myocardial bridges: Overview of ischemic mechanisms and current diognostic and treatment strategies 显示文摘 | Martial G Ady B Jacques L | 2003 | J Am Coll Cardiol2003，41，3： | 1 |
| 14 | Emphysema and pneumothorax after percutaneous tracheostomy: case reports and an anatomic study显示文摘 | Bernard G F Jacques A van V Jan G K | 2004 | Chest2004，125，： | 1 |
| 15 | The importance of registries for pulmonary epithelioid hemangioendothelioma 显示文摘 | Jacques Kpodonu Cimenga Tshibaka Malek G | 2005 | Chest2005，，127： | 1 |
| 16 | Visual acuity and scotomas after one week levodopa administration in human amblyopia显示文摘 | Irene G Jacques Charlier Pobert DR | 1992 | Invest Ophthalmol Vis Sci1992，33，： | 1 |
| 17 | High temperature and water deficit may reduce seed number in field pea purely by decreasing plant growth rate显示文摘 | Lydie G Jacques W Jeremie L | 2003 | Functional Plant Biology2003，30，： | 1 |
| 18 | Pulmonary nodules:delection with thin-acction spiral CT versus conventional CT显示文摘 | Msrtine ILl Jacques R Fredenic G | 1993 | Radiology1993，187，2： | 1 |
| 19 | Model-based automatic target recognition(ATR)system for forward looking groundbased and airborne imaging laser radars(LADAR)显示文摘 | Jacques G Verly Richard L Delanoy | 1996 | Preceedings of the IEEE1996，84，2： | 1 |
| 20 | Dietary essential fatty acid differentially affect tissues of rat显示文摘 | Jeus G Jacques G Brigitte P | 1996 | J Nutr1996，126，： | 1 |
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