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| 1 | Efficiency of HAART in the prevention of mother to children HIV-1 transmission at Saint Camille medical centre in Burkina Faso,West Africa显示文摘Objective:To evaluate efficiency of HAART in the prevention of mother to child HIV transmission.Methods:A longitudinal study was conducted on 1 300 women attending the antenatal service at Saint Camille Medical Centre from September 2010 to July 2011.The HIV status of mothers was determined by rapid tests and EUSA.Discordant results were confirmed by real-time PCR.PCR was used to determine HIV status of children born from HIV-positive mothers.Results:Among 1 300 pregnant women tested for HIV,378 were seropositive.Mothers were predominantly housewives(69.7%),and their mean age was(28.32±0.15) years.The overall prevalence of HIV transmission from mother to child was 4.8%(18/378).This prevalence differed significantly from 0.0%(0/114) to 6.8%(18/264) in children born from mothers under HAART and those with mothers under New Prophylactic Protocol(ACT + 3TC + NVP),respectively(P< 0.01).Children’s mortality rate during the medical follow up was 1.3%(5/378).Among 16 women with HIV dubious status by ELISA,the Real Time PCR confirmed 2/16(12.5%) as HIV positive. Conclusions:The protocol of prevention of mother to children HIV transmission(PMTCT) is effective.The rate of HIV vertical transmission is significantly reduced.Early diagnosis determined by PCR of children born from HIV- positive mother is necessary and recommended in the context of PMTCT in Burkina Faso.We also found that PCR is an effective tool to confirm HIV status in pregnant women. | Laure Stella Ghoma Linguissi Cyrille Bisseye Tani Sagna Bolni Marius Nagalo Djeneba Ouermi Florencia W Djigma Salvatore Pignatelli Joseph D Sia Virginio Pietra Remy Moret Jean Baptiste Nikiema Jacques Simpore | 2012 | Asian Pacific Journal of Tropical Medicine2012，5，12： | 4 |
| 2 | Coronary artery disease in congenital single coronary artery in adults:A Dutch case series显示文摘AIM:To assess the current diagnostic and therapeutic management and the clinical implications of congenital single coronary artery(SCA) in adults.METHODS:We identified 15 patients with a SCA detected from four Dutch angiography centers in the period between 2010 and 2013.Symptomatic patients who underwent routine diagnostic coronary angiography(CAG) for suspected coronary artery disease and who incidentally were found to have isolated SCA were analyzed.RESULTS:Fifteen(7 females) with a mean age of 58.5 ± 13.78 years(range 43-86) had a SCA.ConventionalCAG demonstrated congenital isolated SCA originating as a single ostium from the right sinus of Valsalva in 6 patients and originating from the left in 9 patients.Minimal to moderate coronary atherosclerotic changes were found in 4,and severe stenotic lesions in another 4 patients.Seven patients were free of coronary atherosclerosis.Runs of non-sustained ventricular tachycardia were documented in 2 patients,one of whom demonstrated transmural ischemic changes on presentation.Myocardial perfusion scintigraphic evidence of transmural myocardial ischemia was found in 1 patient due to kinking and squeezing of the SCA with an interarterial course between the aorta and pulmonary artery.Multi-slice computed tomography(MSCT) was helpful to delineate the course of the anomalous artery relative to the aorta and pulmonary artery.Percutaneous coronary intervention was successfully performed in 3 patients.Eight patients were managed medically.Arterial bypass graft was performed in 4 patients with the squeezed SCA.CONCLUSION:SCA may be associated with transient transmural myocardial ischemia and aborted sudden death in the absence of coronary atherosclerosis.The availability and sophistication of MSCT facilitates the delineation of the course of a SCA.We present a Dutch case series and review of the literature. | Salah AM Said Willem G de Voogt Suat Bulut Jacques Han Peter Polak Rogier LG Nijhuis Jeroen W op den Akker Andries Slootweg | 2014 | World Journal of Cardiology2014，6，4： | 3 |
| 3 | High temperature and water deficit may reduce seed number in field pea purely by decreasing plant growth rate显示文摘 | Lydie G Jacques W Jeremie L | 2003 | Functional Plant Biology2003，30，： | 1 |
| 4 | Spinal Metastases:indications for and resuits of percutaneous injection of acrylic surgical cement显示文摘 | Alain W M Jacques C Jean M S | 1996 | Radiology1996，199，3： | 1 |
| 5 | Cytokines, insulin-like growth factor 1, sarcopenia, and mortality in very old community-dwelling men and women: the Framingham Heart Study显示文摘 | Ronenn Roubenoff Helen Parise Hélène A Payette Leslie W Abad Ralph D’Agostino Paul F Jacques Peter W.F Wilson Charles A Dinarello Tamara B Harris | 2003 | The American Journal of Medicine2003，，6： | 1 |
| 6 | Combustion accelerated swir- ling flows in high confinements显示文摘 | Roman W Jacques D | 1992 | Prog Energy Combust1992，18，4： | 1 |
| 7 | Ultrasound of the ankle显示文摘 | CERARDMO R JACQUE B MARC W Y | 2001 | European Journal of Ultrasound2001，14，1： | 1 |
| 8 | Cloning and characterization of Aplysia neutral endopeptidase,a metallo-endopeptidase involved in the extracellular metabolism of neuropeptides in Aplysia californica显示文摘 | Jacques P Z Louise W Wafa B | 1999 | The Journal of Neuroscience1999，19，11： | 1 |
| 9 | A phenomenological model of the bioleaching of complex sulfide ores显示文摘 | Jacques V W Paulina R | 1989 | Hydrometallurgy1989，22，： | 1 |
| 10 | Indirect modulation by α7 nicotinic acetylcholine receptors of noradrenaline release in rat hippocampal slices:Interaction with glutamate and GABA systems and effect of nicotine withdrawal显示文摘 | Jacques B Susan W | 2006 | Mol Pharmacol2006，69，2： | 1 |
| 11 | Comparative hemolytic effectiveness of 1 MHz ultrasound on human and rabbit blood in vitro显示文摘 | Jacques S A Miller Morton W Battaglia Linda F | 2003 | Ultrasound in Med & Biol2003，29，6： | 1 |
| 12 | Determinants of plasma total homocysteine concentration in Framingham offspring cohort显示文摘 | Jacques P F Bostom A G Wilson P W | 2001 | Am J Clin Nutr2001，73，3： | 1 |
| 13 | Comparison of spectrophotometric and visual reading of nccls method and evaluation of a colorimetric method based on reduction of soluble tetrazolium salt,2,3-Bis { 2-Methoxy-4-NiTro -5 - -2H -Tetrazolium -Hydroxide },for Antifungal Susceptibitity Testing of Aspergillus Species显示文摘 | Johan W Mouton Jacques FGM Meis | 2001 | Journal of Clinical Microbiology2001，39，12： | 1 |
| 14 | An isoflavnone and a coumestan from Erythrina sigmoidea 显示文摘 | Augustin EN Jacques K Timothee W | 1994 | Phytochemistry1994，35，2： | 1 |
| 15 | Grating formation in pure silica-core fibers显示文摘 | Jacques A Michael F Margulis W | 2002 | Optics Letters2002，27，10： | 1 |
| 16 | Colormetric assay for antifungal susceptibility testing of aspergillus specis显示文摘 | Johan W Mouton Jacques FQM Meis | 2001 | Journal of Clinical Microbiology2001，39，： | 1 |
| 17 | DW-RBAC:A formal security model of delegation and revocation in workflow systems显示文摘 | Jacques W Akhil K Paulo B | 2007 | Information Systems2007，32，3： | 1 |
| 18 | A phenomenobgical model of the bioleaching of complex sufidleores显示文摘 | Miguel N H Jacques V W Paullina R | 1989 | Hydrometallurgy1989，22，： | 1 |
| 19 | DW-RBAC: A Formal Security Model of Delegation and Revocation in Workflow Systems显示文摘 | Jacques W Akhil K Paulo B | 2007 | Information Systems2007，32，3： | 1 |
| 20 | State-of-the-art review of erosion modeling in fluid/solids systems 显示文摘 | LYCZKOWSKI Robert W BOUILLARD Jacques X | 2002 | Progress in Energy and Combustion Science2002，28，6： | 1 |
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