|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Clinical Practice Guidelines for the Management of Pain, Agitation, and Delirium in Adult Patients in the Intensive Care Unit显示文摘 | Juliana Barr Gilles L. Fraser Kathleen Puntillo E. Wesley Ely Céline Gélinas Joseph F. Dasta Judy E. Davidson John W. Devlin John P. Kress Aaron M. Joffe Douglas B. Coursin Daniel L. Herr Avery Tung Bryce R. H. Robinson Dorrie K. Fontaine Michael A. Ramsa | 2013 | Critical Care Medicine2013，，1： | 6 |
| 2 | Model combining pre-transplant tumor biomarkers and tumor size shows more utility in predicting hepatocellular carcinoma recurrence and survival than the BALAD models显示文摘AIM To assess the performance of BALAD, BALAD-2 and their component biomarkers in predicting outcome of hepatocellular carcinoma(HCC) patients after liver transplant.METHODS BALAD score and BALAD-2 class are derived from bilirubin, albumin, alpha-fetoprotein(AFP), Lens culinaris agglutinin-reactive AFP(AFP-L3), and des-gammacarboxyprothrombin(DCP). Pre-transplant AFP, AFP-L3 and DCP were measured in 113 patients transplanted for HCC from 2000 to 2008. Hazard ratios(HR) for recurrence and death were calculated. Univariate and multivariate regression analyses were conducted. C-statistics were used to compare biomarker-based to predictive models. RESULTS During a median follow-up of 12.2 years, 38 patients recurred and 87 died. The HRs for recurrence in patients with elevated AFP, AFP-L3, and DCP defined by BALAD cut-off values were 2.42(1.18-5.00), 1.86(0.98-3.52), and 2.83(1.42-5.61), respectively. For BALAD, the HRs for recurrence and death per unit increased score were 1.48(1.15-1.91) and 1.59(1.28-1.97). For BALAD-2, the HRs for recurrence and death per unit increased class were 1.45(1.06-1.98) and 1.38(1.09-1.76). For recurrence prediction, the combination of three biomarkers had the highest c-statistic of 0.66 vs. 0.64, 0.61, 0.53, and 0.53 for BALAD, BALAD-2, Milan, and UCSF, respectively. Similarly, for death prediction, the combination of three biomarkers had the highest c-statistic of 0.66 vs 0.65,0.61, 0.52, and 0.50 for BALAD, BALAD-2, Milan, and UCSF. A new model combining biomarkers with tumor size at the time of transplant(S-LAD) demonstrated the highest predictive capability with c-statistics of 0.71 and 0.69 for recurrence and death. CONCLUSION BALAD and BALAD-2 are valid in transplant HCC patients, but less predictive than the three biomarkers in combination or the three biomarkers in combination with maximal tumor diameter(S-LAD). | Nicha Wongjarupong Gabriela M Negron-Ocasio Roongruedee Chaiteerakij Benyam D Addissie Essa A Mohamed Kristin C Mara William S Harmsen J Paul Theobald Brian E Peters Joseph G Balsanek Melissa M Ward Nasra H Giama Sudhakar K Venkatesh Denise M Harnois Michael R Charlton Hiroyuki Yamada Alicia Algeciras-Schimnich Melissa R Snyder Terry M Therneau Lewis R Roberts | 2018 | World Journal of Gastroenterology2018，24，12： | 5 |
| 3 | Cervical inlet patch-optical coherence tomography imaging and clinical significance显示文摘AIM:To demonstrate the feasibility of optical coherence tomography(OCT)imaging in differentiating cervical inlet patch(CIP)from normal esophagus,Barrett'sesophagus(BE),normal stomach and duodenum. METHODS:This study was conducted at the Veterans Affairs Boston Healthcare System(VABHS).Patients undergoing standard esophagogastroduodenoscopy at VABHS,including one patient with CIP,one representative patient with BE and three representative normal subjects were included.White light video endoscopy was performed and endoscopic 3D-OCT images were obtained in each patient using a prototype OCT system.The OCT imaging probe passes through the working channel of the endoscope to enable simultaneous video endoscopy and 3D-OCT examination of the human gastrointestinal(GI)tract.Standard hematoxylin and eosin(H and E)histology was performed on biopsy or endoscopic mucosal resection specimens in order to compare and validate the 3D-OCT data. RESULTS:CIP was observed from a 68-year old male with gastroesophageal reflux disease.The CIP region appeared as a pink circular lesion in the upper esophagus under white light endoscopy.OCT imaging over the CIP region showed columnar epithelium structure,which clearly contrasted the squamous epithelium structure from adjacent normal esophagus.3D-OCT images obtained from other representative patients demonstrated distinctive patterns of the normal esophagus,BE,normal stomach,and normal duodenum bulb.Microstructures,such as squamous epithelium,lamina propria, muscularis mucosa,muscularis propria,esophageal glands,Barrett's glands,gastric mucosa,gastric glands, and intestinal mucosal villi were clearly observed with OCT and matched with H and E histology.These results demonstrated the feasibility of using OCT to evaluate GI tissue morphology in situ and in real-time. CONCLUSION:We demonstrate in situ evaluation of CIP microstructures using 3D-OCT,which may be a useful tool for future diagnosis and follow-up of patients with CIP. | Chao Zhou Tejas Kirtane Tsung-Han Tsai Hsiang-Chieh Lee Desmond C Adler Joseph M Schmitt Qin Huang James G Fujimoto Hiroshi Mashimo | 2012 | World Journal of Gastroenterology2012，18，20： | 3 |
| 4 | Deep learning in hepatocellular carcinoma:Current status and future perspectives显示文摘Hepatocellular carcinoma(HCC)is among the leading causes of cancer incidence and death.Despite decades of research and development of new treatment options,the overall outcomes of patients with HCC continue to remain poor.There are areas of unmet need in risk prediction,early diagnosis,accurate prognostication,and individualized treatments for patients with HCC.Recent years have seen an explosive growth in the application of artificial intelligence(AI)technology in medical research,with the field of HCC being no exception.Among the various AI-based machine learning algorithms,deep learning algorithms are considered state-of-the-art techniques for handling and processing complex multimodal data ranging from routine clinical variables to high-resolution medical images.This article will provide a comprehensive review of the recently published studies that have applied deep learning for risk prediction,diagnosis,prognostication,and treatment planning for patients with HCC. | Joseph C Ahn Touseef Ahmad Qureshi Amit G Singal Debiao Li Ju-Dong Yang | 2021 | World Journal of Hepatology2021，13，12： | 2 |
| 5 | Clinical Practice Guidelines for the Management of Pain, Agitation, and Delirium in Adult Patients in the Intensive Care Unit显示文摘 | Juliana Barr Gilles L. Fraser Kathleen Puntillo E. Wesley Ely Céline Gélinas Joseph F. Dasta Judy E. Davidson John W. Devlin John P. Kress Aaron M. Joffe Douglas B. Coursin Daniel L. Herr Avery Tung Bryce R. H. Robinson Dorrie K. Fontaine Michael A. Ramsa | 2013 | Critical Care Medicine2013，，1： | 2 |
| 6 | Slow breathing improves arterial baroreflex sensitivity and decreases blood pressure in es- sential hypertension 显示文摘 | Joseph CN Porta C Casucci G | 2005 | Hypertension2005，46，4： | 1 |
| 7 | Coumarin dyes for dye-sensitized solar cells:a long-range-corrected density functional study 显示文摘 | Bryan M W Joseph G C | 2008 | Journal of Chemical Physics2008，129，21： | 1 |
| 8 | Pituitary adenoma:correlation of half-dose gadolinium-enhanced MR imaging with surgical findings in 26 patients显示文摘 | Davis P C Gokhale K A Joseph G J | 1991 | Radiology1991，180，3： | 1 |
| 9 | Detection of rinderpest virus using N-protein monoclonal antibodies 显示文摘 | Shan R A Joseph M C Butchaiah G | 2004 | Tropical Animal Health and Production2004，36，1： | 1 |
| 10 | Granular cell tumours of the gastrointestinal tract:expression of nestin and clinicopathological evaluation of 11 patients显示文摘 | Parfitt J R McLean C A Joseph M G | 2006 | Histopathology2006，48，： | 1 |
| 11 | Pituitary adenoma:correlation of half-dose gadolinium-enhanced MR imaging with surgical findings in 26 patients显示文摘 | Davis P C Gokhale K A Joseph G J | 1991 | Radiology1991，180，3： | 1 |
| 12 | Extraction and characterisation of lipids from Antarctic krill (Euphausia superba)显示文摘 | JOSEPH C G MATTHEW P D SARAH K B | 2010 | Food Chemistry2010，125，3： | 1 |
| 13 | Synthesis and characteriza- tion of inorganic silicon oxycarbide glass thin fihns by reac- tive rf-magnetron sputtering 显示文摘 | Joseph V Ryan Pantano C G | 2007 | J Vac Sci Technol A2007，25，1： | 1 |
| 14 | Recent advance in techniques for hyperspectral image processing显示文摘 | Antonio P Jon A B Joseph W B Jason B Lorenzo B Gustavo C V Jocelyn C Mathieu F Paolo G Anthony G Mattia M James C T Giovanna T | 2009 | Remote Sensing of Environment2009，113，： | 1 |
| 15 | Evaluation of bacteria isolated from rice for plant growth promotion and biological control of seedling disease of rice显示文摘 | Adhikari T B Joseph C M Yang G | 2001 | Can J Microbiol2001，47，： | 1 |
| 16 | Use of three- dimensional guglielmi detachable coils in the treatment of wide - necked cerebral aneurysms 显示文摘 | CLOFT H J JOSEPH G J TONG F C | 2000 | Am J Neuroradiol2000，21，： | 1 |
| 17 | Extraction and characterization of lipids from Antarctic krill(Euphausia superba)显示文摘 | Joseph C G Matthew P D Sarah K B | 2011 | Food Chemistry2011，，125： | 1 |
| 18 | Sonophotocatalysis in advanced oxidation process : a short review 显示文摘 | Joseph C G Puma G L Bono A | 2009 | Ultra- son Sonochem2009，16，5： | 1 |
| 19 | Evaluation of bacteria isolated from rice for plant growth promotion and biological control of seedling disease of rice显示文摘 | ADHIKARI T B JOSEPH C M YANG G | 2001 | Can J Microbiol2001，，47： | 1 |
| 20 | Tacrolimus for the treatment of fistulas in patients with crohn’s disease: a randomized, placebo-controlled trial显示文摘 | William J Sandborn Daniel H Present Kim L Isaacs Douglas C Wolf Eugene Greenberg Stephen B Hanauer Brian G Feagan Lloyd Mayer Therese Johnson Joseph Galanko Christopher Martin Robert S Sandler | 2003 | Gastroenterology2003，，2： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员