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| 1 | 深度学习神经网络在肝癌诊疗中的研究及应用前景显示文摘原发性肝癌(肝癌)是2020年全球第五大最常见的癌症和第二大癌症相关死亡原因[1]。2003~2015年肝癌是我国第三常见的恶性肿瘤,5年生存率12.1%,在所有侵袭性癌症中排名第二[2]。可以说肝癌一直是困扰我国国民健康的重大健康问题,随着医疗设备、药品开发和治疗技术的飞跃,数十年内肝癌的在诊断和治疗上经历了一个又一个突破性进展。然而,数千年来,以一位医师或几位医师组成的多学科团队依据其理论基础和既往经验综合分析患者的临床数据进行疾病诊断和治疗为核心的医疗模式从未改变。近年来,人工智能(artificial intelligence,AI)的快速发展逐渐显示出对这一核心医疗模式的重大挑战。特别是深度学习(deep learning,DL)的出现,尤其凭借其在图像处理方面显示的独特优势,可能会在医学领域带来划时代的变化。 | 韩冰 顾劲扬 | 2023 | 中华肝脏外科手术学电子杂志2023，12，5： | 0 |
| 2 | From prediction to prevention:Machine learning revolutionizes hepatocellular carcinoma recurrence monitoring显示文摘In this editorial,we comment on the article by Zhang et al entitled Development of a machine learning-based model for predicting the risk of early postoperative recurrence of hepatocellular carcinoma.Hepatocellular carcinoma(HCC),which is characterized by high incidence and mortality rates,remains a major global health challenge primarily due to the critical issue of postoperative recurrence.Early recurrence,defined as recurrence that occurs within 2 years posttreatment,is linked to the hidden spread of the primary tumor and significantly impacts patient survival.Traditional predictive factors,including both patient-and treatment-related factors,have limited predictive ability with respect to HCC recurrence.The integration of machine learning algorithms is fueled by the exponential growth of computational power and has revolutionized HCC research.The study by Zhang et al demonstrated the use of a groundbreaking preoperative prediction model for early postoperative HCC recurrence.Challenges persist,including sample size constraints,issues with handling data,and the need for further validation and interpretability.This study emphasizes the need for collaborative efforts,multicenter studies and comparative analyses to validate and refine the model.Overcoming these challenges and exploring innovative approaches,such as multi-omics integration,will enhance personalized oncology care.This study marks a significant stride toward precise,efficient,and personalized oncology practices,thus offering hope for improved patient outcomes in the field of HCC treatment. | Mariana Michelle Ramírez-Mejía Nahum Méndez-Sánchez | 2024 | World Journal of Gastroenterology2024，30，7： | 0 |
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