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| 1 | Relationship between T-lymphocyte cytokine levels and sero-response to hepatitis B vaccines显示文摘AIM: To investigate the cellular defects by analyzing the (Th1/Th2) cytokine levels in vaccine responders and non-responders. METHODS: Peripheral blood mononuclear cell (PBMC) from responders and non-responders were stimulated with or with out recombinant HBsAg or PHA. Broad spectrum of cytokines viz (Th1) IFN-γ, IL-2, TNF-α, IL-12 and (Th2) IL-10, IL-4 were measured after in vitro stimulation with recombinant HBsAg and were compared with respective antibody titers. RESULTS: A significant decrease (P = 0.001) in Th1 and Th2 cytokines namely, IL-2, INF-γ, TNF-α and IL-10in non-responders was observed. The level of IL-4 was not significant between the three groups. Furthermore, despite a strong Th1 and Th2 cytokine response, the level of IL-12 was elevated in high-responders compared to other groups (P = 0.001) and demonstrated a positive correlation with anti-HBs titers and Th1 cytokine response. CONCLUSION: Our findings suggest that unrespon-siveness to recombinant hepatitis B vaccines (rHB) is multifactorial, including specific failure of antigen presentation or the lack of both T helper Th1 and Th2 response. | Vijayakumar Velu Shanmugam Saravanan Subhadra Nandakumar Esaki Muthu Shankar Appasamy Vengatesan Suresh Sakharam Jadhav Prasad Suryakant Kulkarni Sadras Panchatcharam Thyagarajan | 2008 | World Journal of Gastroenterology2008，14，22： | 22 |
| 2 | L-Proline Catalyzed Solvent-Free Knoevenagel Condensation for the Synthesis of 3-Substituted Coumarins显示文摘当为由有反应甲又的代替的 2-hydroxybenzaldehydes 的 Knoevenagel 冷凝作用的 3 代用品香豆素的环境地良性的合成的有效 organo 催化剂在溶剂下面加重免费条件, L 脯氨酸被利用。 | KARADE, Nandkishor. N. GAMPAWAR, Sumit V. SHINDE, Sandeep. V. JADHAV, Wamanrao. N. | 2007 | Chinese Journal of Chemistry2007，25，11： | 6 |
| 3 | 健康领域的文化能力显示文摘1背景
尽管人类对其他社会的兴趣纵贯历史的各个阶段,但是检验不同文化概念对人类健康实践的影响从20世纪才开始,当时是伴随着长期的人类学田野调查产生的,这些田野调查揭露了不同文化之间相关卫生实践的多样性、复杂性和连续性。 | Napier A D Ancarno C Butler B Calabrese j Chater A Chatterjee H Guesnet F Home R Jacyna S Jadhav S Macdonald A Neuendorf U Parkhurst A Reynolds R Scambler G Shamdasani S Smith S Z Stougaard-Nielsen J Thomson L Tyler N Volkmann A M Walker T Watson J Williams AC Willott C Wilson J Woolf K | 2016 | 中国卫生政策研究2016，9，2： | 5 |
| 4 | Comparison of three different recombinant hepatitis B vaccines:GeneVac-B,Engerix B and Shanvac B in high risk infants born to HBsAg positive mothers in India显示文摘AIM: To evaluate a low cost Indian recombinant hepatitis B vaccine GeneVac-B for its immunogenicity and safety in comparison to Engerix B and Shanvac B vaccine in high risk newborn infants born to hepatitis B surface antigen (HBsAg) positive mothers. METHODS: A total of 158 infants were enrolled in the study. Fifty eight infants were enrolled in the GeneVac-B group while 50 each were included for Engerix B and Shanvac B groups. A three-dose regimen of vaccination; at birth (within 24 h of birth), 1st mo and 6 mo. were adopted with 10 μg dosage administered uniformly in all the three groups. Clinical and immunological parameters were assessed for safety and immunogenicity of the vaccines, in all the enrolled infants. RESULTS: Successful follow up until seven months of age was achieved in 83/ (48/58) for GeneVac-B, 76/ (38/50) and 64/ (32/50) for Engerix B and Shanvac B groups respectively. 100/ seroconversion and seroprotection was achieved in all the three groups of infants. The geometric mean titers of anti-HBs one month after the completion of three dose of vaccination were 90.5, 80.9 and 72.5 mIU/mL in GeneVac-B, Engerix B and Shanvac B vaccine group respectively. Furthermore the level of anti-HBs increases with age ofbabies who were born to HBsAg positive mothers. The GMT values of anti-HBs were 226.7, 193.9 and 173.6 mIU/mL respectively in GeneVac-B, Engerix B and Shanvac B groups one year after the completion of the three doses of vaccine. No systemic reactions were reported in infants during the entire vaccination process of GeneVac-B and the other two vaccines. Clinical safety parameters remained within the normal limits throughout the study period.CONCLUSION: The study concludes that there is no significant difference between the three recombinant hepatitis B vaccines. Administration of these vaccines within 24 h of birth to babies, born to HBsAg positive mothers will reduce the incidence of HBV infection. | Vijayakumar Velu Subhadra Nandakumar Saravanan Shanmugam Suresh Sakharam Jadhav Prasad Suryakant Kulkarni Sadras Panchatcharam Thyagarajan | 2007 | World Journal of Gastroenterology2007，13，22： | 4 |
| 5 | Exploiting Natural Variation in Tomato to Define Pathway Structure and Metabolic Regulation of Fruit Polyphenolics in the Lycopersicum Complex显示文摘While the structures of plant primary metabolic pathways are generally well defined and highly conserved across species,those defining specialized metabolism are less well characterized and more highly variable across species.In this study,we investigated polyphenolic metabolism in the lycopersicum complex by characterizing the underlying biosynthetic and decorative reactions that constitute the metabolic network of polyphenols across eight different species of tomato.For this purpose,GC-MS-and LC-MS-based metabolomics of different tissues of Solatium lycopersicum and wild tomato species were carried out,in concert with the evaluation of cross-hybridized microarray data for MapMan-based transcriptomic analysis,and publicly available RNA-sequencing data for annotation of biosynthetic genes.The combined data were used to compile species-specific metabolic networks of polyphenolic metabolism,allowing the establishment of an entire pan-species biosynthetic framework as well as annotation of the functions of decoration enzymes involved in the formation of metabolic diversity of the flavonoid pathway.The combined results are discussed in the context of the current understanding of tomato flavonol biosynthesis as well as a global view of metabolic shifts during fruit ripening.Our results provide an example as to how large-scale biology approaches can be used for the definition and refinement of large specialized metabolism pathways. | Takayuki Tohge Federico Scossa Regina Wendenburg Pierre Frasse llse Balbo Mutsumi Watanabe Saleh Alseekh Sagar Sudam Jadhav Jay C.Delfin Marc Lohse Patrick Giavalisco Bjoern Usadel Youjun Zhang Jie Luo Mondher Bouzayen Alisdair R.Fernie | 2020 | Molecular Plant2020，13，7： | 3 |
| 6 | Effect of Cation Proportion on the Structural and Magnetic Properties of Ni-Zn Ferrites Nano-Size Particles Prepared By Co-Precipitation Technique显示文摘有一般公式 Ni 1−x Zn x Fe 2 有 x = 的 O 4 0.0, 0.1, 0.2, 0.3, 0.4, 0.5, 0.6,和 0.7 被湿化学一起沉淀准备方法。结构并且磁性借助于 X 光检查衍射,磁化,和交流危险性大小被学习。X 光检查分析证实了样品的单相的形成。从 XRD 数据获得的格子参数被发现与 Zn 内容 x 增加。阳离子分发被 X 光检查紧张比率计算学习。磁化结果展出在同一直线上的含铁为 x ≤
的磁性的结构0.4,并且哪个的变化为 x>0.4 非在同一直线上。居里温度 T 从交流危险性数据获得的 C 与增加 x 减少。 | Santosh S. Jadhav Sagar E. Shirsath B. G. Toksha S. J. Shukla K. M. Jadhav | 2008 | Chinese Journal of Chemical Physics2008，21，4： | 3 |
| 7 | 水稻产量及其相关性状的数量性状位点(QTL)鉴定(英文)显示文摘由于大部分水稻育种的最终目标是获得高产、稳产,因此对于育种工作者来说,水稻产量及其构成因素是重要的性状。在大田试验中,采用随机区组设计,设两个重复,对CT 9993-5-10-1-M×IR 62266-42-6-2杂交而得的144份水稻品系DH群体的产量及其主要农艺性状的数量性状位点(QTL s)进行定位。采用M APM AKER/QTL1.1软件进行区间定位并估计每个QTL的表型方差的百分比,以LOD阈值>2.4来确定一个QTL的有无。试验鉴定出与6个水稻农艺性状如千粒重、单株产量、株高、穗长、粒宽、粒长宽比有关的23个QTL s,这些QTL s将有助于提高水稻产量,并有利于了解水稻产量性状的遗传调控。 | Deshmukh Rupesh Sonah Humira Tiwari Anshuman Mahatman Krityanand Jadhav Srikrishna Kadam Suhas Kesawat Mahipal Reddy Niranjan Deshmukh Nilesh Verulkar Satish | 2008 | 广西农业科学2008，39，5： | 2 |
| 8 | Thick ceramic thermal barrier coatings with high durability deposited using solution-precursor plasma spray显示文摘 | Amol Jadhav Nitin P. Padture Fang Wu Eric H. Jordan Maurice Gell | 2005 | Materials Science & Engineering A2005，，1： | 2 |
| 9 | 文化、不平等性与卫生服务提供显示文摘1动态不平等性对基层医疗卫生人力的影响
政治、社会、文化、专业群体皆建立在一致且常规的人类行为之上。当遭受巨大变革和内外压力时,这些群体会变得十分脆弱。尤其在动荡时期,这些群体往往更关注社会和文化的差异性,而非二者的一致性。尽管社会中的个体思维和行为会呈现较大的差异,但对健康的感知具有统一性,并在更广范围人群内尤为突出,这主要归因于文化价值观的作用。广义的文化心态会随着时间和地理位置的不同而不同,就像健康的社会决定因素也会因文化类型的不同而产生差异。 | Napier A D Ancarno C Butler B Calabrese J Chater A Chatterjee H Guesnet F Horne R Jacyna S Jadhav S Macdonald A Neuendorf U Parkhurst A Reynolds R Scambler G Shamdasani S Smith S Z Stougaard-Nielsen J Thomson L Tyler N Volkmann A M Walker T Watson J Williams A C Willott C Wilson J Woolf K | 2016 | 中国卫生政策研究2016，9，3： | 2 |
| 10 | Preparation, characterization, and kinetic study of end opened carbon nanotubes incorporated polyacrylonitrile electrospun nanofibers for the adsorption of pyrene from aqueous solution显示文摘 | Arvind H. Jadhav Xuan Thang Mai Frank A. Ofori Hern Kim | 2015 | Chemical Engineering Journal2015，，： | 2 |
| 11 | Extremely unusual case of gastrointestinal trichobezoar显示文摘Trichobezoars(hair ball) are usually located in the stomach, but may extend through the pylorus into the duodenum and small bowel(Rapunzel syndrome). Rapunzel syndrome remains uncommon; with fewer than 40 cases reported. To the best of our knowledge, this case may be the first well-documented case with a length of 75 cm. They are almost always associated with trichotillomania and trichophagia or other psychiatric disorders. In the literature several treatment options are proposed, including removal by conventional laparotomy, laparoscopy and endoscopy. Herein, we are reporting an interesting case of an 18-year mentally retarded girl with history of trichotillomania and trichophagia who presented to our emergency department with a history of central abdominal pain associated with vomiting and constipation for five days. An examination showed a trichobezoar requiring emergent surgical intervention, and indicating the need for psychiatric treatment. The trichobezoar was treated successfully by laparoscopy. | Sopan N Jatal Nawab P Jamadar Bhagwat Jadhav Saleha Siddiqui Sachin B Ingle | 2015 | World Journal of Clinical Cases2015，3，5： | 2 |
| 12 | 糖尿病酮症酸中毒患者发生胃肠道出血的预测因素:一项回顾性的观察研究显示文摘背景酮症酸中毒(DKA)是糖尿病一种常见的急性并发症,需要积极的药物治疗。我们旨在研究DKA患者急性胃肠道出血(AGIB)和急性上消化道出血(AUGIB)的发生率及其相关危险因素。方法:我们对本中心2010年1月至2015年12月间收治的DKA病例进行回顾性分析,通过电子病历库收集其人口统计学、临床、实验室、内镜及住院资料。根据有无发生胃肠道出血将患者分为两组。结果:共计234例DKA患者纳入研究,其中27例(11.5%)有AGIB的记录。除2例直肠出血和3例隐匿性出血外,22例(9.4%)表现为呕血。AGIB组与非AGIB组患者年龄、性别和种族的分布无显著差异。两组患者电解质水平、阴离子间隙、pH值及糖化血红蛋白HbA1c的差异亦无统计学意义。然而,AGIB组患者初始血糖水平显著高于非AGIB组(738 mg/dL vs 613 mg/dL,P=0.014)。AGIB组患者病死率也有所升高(7.4%vs 4.8%),尽管差异未达到统计学意义。结论:初始高血糖水平会增加DKA患者发生AGIB的风险。我们还注意到发生AGIB的DKA患者病死率增加,尽管这个增加未达到统计学意义。临床上应更加积极地纠正DKA患者的血糖水平以降低AGIB发生率,从而降低住院病死率。 | Kanthi Rekha Badipatla Preeti Jadhav Sushma Vaddigiri Bharat Bajantri Amandeep Singh Chaitanya Chandrala Vijay S Are Suresh Kumar Nayudu | 2017 | Gastroenterology Report2017，5，4： | 2 |
| 13 | Bile acid receptors in non-alcoholic fatty liver disease显示文摘 | Yuanyuan Li Kavita Jadhav Yanqiao Zhang | 2013 | Biochemical Pharmacology2013，，11： | 2 |
| 14 | Amine loaded zeolites for carbon dioxide capture: Amine loading and adsorption studies显示文摘 | Ravikrishna Chatti Amit K. Bansiwal Jayashri A. Thote Vivek Kumar Pravin Jadhav Satish K. Lokhande Rajesh B. Biniwale Nitin K. Labhsetwar Sadhana S. Rayalu | 2009 | Microporous and Mesoporous Materials2009，，1： | 2 |
| 15 | Selective and Cell-Active Inhibitors of the USP1/ UAF1 Deubiquitinase Complex Reverse Cisplatin Resistance in Non-small Cell Lung Cancer Cells显示文摘 | Junjun Chen Thomas S. Dexheimer Yongxing Ai Qin Liang Mark A. Villamil James Inglese David J. Maloney Ajit Jadhav Anton Simeonov Zhihao Zhuang | 2011 | Chemistry & Biology2011，，11： | 2 |
| 16 | Abscess formation in invasive pituitary adenoma : case report显示文摘 | Jadhav RN Dahiwadkar HV Palande DA | 1998 | Neurosurgery1998，43，3： | 1 |
| 17 | Alkaloids from Heimiasalicifolia显示文摘 | Rumalla CS Jadhav AN Smillie T | 2008 | Phytochemistry2008，69，8： | 1 |
| 18 | Text-inde- pendent speaker identification using radon and discrete co- sine transforms based features from speech spectrogram显示文摘 | MMERA P K JADHAV D V HOLAMBE R S | 2011 | Pattern Recognition2011，44，1011： | 1 |
| 19 | Fermentation and characterization of apricot and raisin wine by Saccharomyces cerevisiae NCIM 3282 显示文摘 | Bapat R K Jadhav S B Ghosh J S | 2010 | Research Journal of Microbiology2010，5，11： | 1 |
| 20 | A new grading system evaluating bleeding scale in filament perforation subarachnoid hemorrhage rat model显示文摘 | SUGAWARA T AYER R JADHAV V | 2008 | J Neurosci Methods2008，167，2： | 1 |
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