|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Second-look surgery plus hyperthermic intraperitoneal chemotherapy for patients with colorectal cancer at high risk of peritoneal carcinomatosis:Does it really save lives?显示文摘The treatment of peritoneal carcinomatosis (PC) of colorectal origin with cytoreductive surgery(CRS) plus hyperthermic intraperitoneal chemotherapy (HIPEC) has a 5-year recurrence-free or cure rate of at least 16%, so it is no longer labeled as a fatal disease, and offers prolonged survival for patients with a low peritoneal carcinomatosis index. Metachronous PC of colorectal origin is so predictable that there is a model which has been used to successfully determine the individual risk of each patient. Patients at risk are clearly identified; those with the highest risk have small peritoneal nodules present in the first surgery (70% probability of developing PC), ovarian metastases(60%), perforated tumor onset or intraoperative tumor rupture(50%). Current clinical, biological and imaging techniques still lack sufficient sensitivity to diagnose PC in its initial stages, when CRS plus HIPEC has a greater impact and a higher cure rate. Second-look surgery with HIPEC or prophylactic HIPEC at the time of the first intervention have been proposed as means of preventing and/or anticipating clinical or radiological relapse in at-risk patients. Both techniques have shown a significant decrease in peritoneal relapses and should be considered essential weapons in the management of colorectal cancer. | Delia Cortes-Guiral Dominique Elias Pedro Antonio Cascales-Campos Alfredo Badía Yébenes Ismael Guijo Castellano Ana Isabel León Carbonero JoséIgnacio Martín Valadés Jesus Garcia-Foncillas Damian Garcia-Olmo | 2017 | World Journal of Gastroenterology2017，23，3： | 3 |
| 2 | Are family firms really superior performers?显示文摘 | Danny Miller Isabelle Le Breton-Miller Richard H. Lester Albert A. Cannella | 2007 | Journal of Corporate Finance2007，，5： | 3 |
| 3 | A randomized phase II study to compare oxaliplatin plus 5-fluorouracil and leucovorin (FOLFOX4) versus oxaliplatin plus raltitrexed (TOMOX) as first-line chemotherapy for advanced colorectal cancer显示文摘 | Cristina Gravalos Antonieta Salut Carlos García-Girón Rocío García-Carbonero Ana León Isabel Sevilla Joan Maurel Beatriz Esteban Eduardo García-Rico Adolfo Murias Hernán Cortés-Funes | 2012 | Clinical and Translational Oncology2012，，8： | 2 |
| 4 | Epidemiology and Treatment Costs of Bone Metastases from Lung Cancer: A French Prospective, Observational, Multicenter Study (GFPC 0601)显示文摘 | Chantal Decroisette Isabelle Monnet Henri Berard Gilles Quere Herve Le Caer Suzanna Bota Clarisse Audigier-Valette Laurence Geriniere Jean-Marc Vernejoux Christos Chouaid | 2011 | Journal of Thoracic Oncology2011，，3： | 2 |
| 5 | Motility of the Roux-en-Y hepaticojejunostomy in asymptomatic patients显示文摘 | Isabelle Le Blanc-Louvry Philippe Ducrotté Jean Luc Manouvrier Christophe Peillon Jacques Testart Philippe Denis | 1999 | The American Journal of Gastroenterology1999，，9： | 2 |
| 6 | Direct observation of photonic Landau levels and helical edge states in strained honeycomb lattices显示文摘We report the realization of a synthetic magnetic field for photons and polaritons in a honeycomb lattice of coupled semiconductor micropillars.A strong synthetic field is induced in both the s and p orbital bands by engineering a uniaxial hopping gradient in the lattice,giving rise to the formation of Landau levels at the Dirac points.We provide direct evidence of the sublattice symmetry breaking of the lowest-order Landau level wavefunction,a distinctive feature of synthetic magnetic fields.Our realization implements helical edge states in the gap between n=0 and n=±1 Landau levels,experimentally demonstrating a novel way of engineering propagating edge states in photonic lattices.In light of recent advances in the enhancement of polariton–polariton nonlinearities,the Landau levels reported here are promising for the study of the interplay between pseudomagnetism and interactions in a photonic system. | Omar Jamadi Elena Rozas Grazia Salerno Marijana Milicevic Tomoki Ozawa Isabelle Sagnes Aristide Lemaitre Luc Le Gratiet Abdelmounaim Harouri Iacopo Carusotto Jacqueline Bloch Alberto Amo | 2020 | Light(Science & Applications)2020，9，1： | 2 |
| 7 | Transcriptional Activation of Apolipoprotein CIII Expression by Glucose May Contribute to Diabetic Dyslipidemia显示文摘 | Sandrine Caron An Verrijken Ilse Mertens Carolina Huaman Samanez Gisèle Mautino Joel T. Haas Daniel Duran-Sandoval Janne Prawitt Sven Francque Emmanuelle Vallez Anne Muhr-Tailleux Isabelle Berard Folkert Kuipers Jan A. Kuivenhoven Sudha B. Biddinger Marja | 2011 | Arteriosclerosis Thrombosis and Vascular Biology2011，，3： | 1 |
| 8 | Leucine supplementation im- proves muscle protein synthesis in elderly men independently of hy- peraminoacidaemia显示文摘 | Isabelle R Mich~le B Claire S | 2006 | The Journal of Physilolgy2006，575，： | 1 |
| 9 | Use of HepG2 cell line for direct or indirect mutagens screening: comparative investigation between comet and micronucleus assays显示文摘 | Isabelle Valentin-Severin Ludovic Le Hegarat Jean-Claude Lhuguenot Anne-Marie Le Bon Marie-Christine Chagnon | 2003 | MutRes-Genetic Toxicology and Environmental Mutagenesis2003，，1： | 1 |
| 10 | An integrated shadow-mask based on a stack of imorganic insnlators for high-resolution OLEDs using evaporated or spun-on material显示文摘 | Christophe P Dan Roth Isabelle Le'vesque | 2001 | Synthetic Metals2001，122，： | 1 |
| 11 | Distribution and speciation of ambient selenium in contrasted soils, from mineral to organic rich显示文摘 | Julie Tolu Yves Thiry Ma?té Bueno Claudy Jolivet Martine Potin-Gautier Isabelle Le Hécho | 2014 | Science of the Total Environment2014，，： | 1 |
| 12 | Analysis of cir- cadian and uhradian rhythms of skin surface properties of face and fore- arm of healthy women显示文摘 | Le Fur Isabelle Reinberg Alain Lopez Sabine | 2001 | Journal of investigative dermatology2001，117，3： | 1 |
| 13 | 2 -Chlorophenyl Zinc Bromide : A Convenient Nucleophile forthe Mannich -Related Multicomponent Synthesis of Clopidogrel and Ticlopidine 显示文摘 | Isabelle Aillaud Caroline Haurena Erwan Le Gall | 2010 | molecules2010，，15： | 1 |
| 14 | C-Reactive protein and coronary artery disease: Additional evidence of the implication of an inflammatory process in acute coronary syndromes显示文摘 | Idrissia Abdelmouttaleb Nicolas Danchin Claudio Ilardo Isabelle Aimone-Gastin Michael Angio? Alain Lozniewski Julien Loubinoux Alain Le Faou Jean-Louis Guéant | 1999 | American Heart Journal1999，，2： | 1 |
| 15 | TBT and TPhT persistence in a sludged soil显示文摘 | MARCIC CHRISTOPHE LE ISABELLE HECHO DENAIX LAURENCE | 2006 | Chemosphere2006，65，11： | 1 |
| 16 | Sorafenib in patients with progressive epithelioid hemangioendothelioma显示文摘 | Christine Chevreau Axel Le Cesne Isabelle Ray‐Coquard Antoine Italiano Angela Cioffi Nicolas Isambert Yves Marie Robin Charles Fournier Stéphanie Clisant Loic Chaigneau Jacques‐Olivier Bay Emmanuelle Bompas Eric Gauthier Jean Y. Blay Nicolas Penel | 2013 | Cancer2013，，14： | 1 |
| 17 | Value co-creationamongretailersandconsumers: newin- sightsinto the furniture market显示文摘 | LUISA ANDREU ISABELS h NCHEZ CRISTINA ME- LE | 2010 | Journal of Retailing and Consumer Services2010，，17： | 1 |
| 18 | Operative stress response is reduced after lapoarscopic compared to open chole cystectomy: the relationship with postoperative pain and ileus 显示文摘 | Isabelle LE Antoine MD Edith K | 2000 | Dig Dis Sci2000，45，9： | 1 |
| 19 | Evaluation and selection of tandem repeat loci for a Brucella MLVA typing assay 显示文摘 | Le Fleche P Isabelle J Maggy G | 2006 | BMC Microbiol2006，6，9： | 1 |
| 20 | How to detect a management fad—and distinguish it from a classic显示文摘 | Danny Miller Jon Hartwick Isabelle Le Breton-Miller | 2004 | Business Horizons2004，，4： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员