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| 1 | Quadruple therapy with moxifloxacin and bismuth for first-line treatment ofHelicobacter pylori显示文摘AIM:To compare triple therapy vs quadruple therapy for 10 d as first-line treatment ofHelicobacter pylori(H.pylori) infection.METHODS:Consecutive H.pylori positive patients never treated in the past for this infection were randomly treated with triple therapy of pantoprazole(PAN) 20 mg bid,amoxicillin(AMO) 1 g bid and moxifloxacin(MOX) 400 mg bid for 10 d(PAM) or with quadruple therapy of PAN 20 mg bid,AMO 1 g bid,MOX 400 mg bid and bismuth subcitrate 240 mg bid for 10 d(PAMB).All patients were found positive at 13 C-Urea breath test(UBT) performed within ten days prior to the start of the study.A successful outcome was confirmed with an UBT performed 8 wk after the end of treatment.χ 2 analysis was used for statistical comparison.Per protocol(PP) and intention-to-treat(ITT) values were also calculated.RESULTS:Fifty-seven patients were enrolled in the PAM group and 50 in the PAMB group.One patient in each group did not return for further assessment.Eradication was higher in the PAMB group(negative:46 and positive:3) vs the PAM group(negative:44 and positive:12).The H.pylori eradication rate was statistically significantly higher in the PAMB group vs the PAM group,both with the PP and ITT analyses(PP:PAMB 93.8%,PAM 78.5%,P < 0.02;ITT:PAMB 92%,PAM 77.1 %,P <0.03).CONCLUSION:The addition of bismuth subcitrate can be considered a valuable adjuvant to triple therapy in those areas where H.pylori shows a high resistance to fluoroquinolones. | Antonio Francesco Ciccaglione Luigina Cellini Laurino Grossi Leonardo Marzio | 2012 | World Journal of Gastroenterology2012，18，32： | 5 |
| 2 | Osmoprotectants and Antioxidative Enzymes as Screening Tools for Salinity Tolerance in Radish (Raphanus sativus)显示文摘The research addresses the identification of a screening methodology for salt stress tolerance in radish cultivars. In the first experiment, two different radish cultivars(long white and round red) were compared in their morphological and physiological responses to different salinity levels. Round red radish showed better morphological and physiological responses to incremental salinity in terms of yield and better adaptation of overall water relations. In the second experiment, the most tolerant genotype from the first experiment was used as a control against other seven round red radish genotypes ranked by their salinity tolerance according to morphological, physiological and biochemical indices. Salt stress did not significantly affect malondialdehyde(MDA) and hydrogen peroxide(H2O2) content, and ascorbate peroxidase(APX) activity in the studied cultivars. Nonetheless, the relatively salt tolerant cultivar SAXA2 showed higher ability to accumulate compatible solutes(e.g.proline and proteins) and maintain osmotic adjustment. In addition, cultivar SAXA2 also showed considerable increase in glutathione reductase(GR) activity. Our results supported that accumulation of proline and higher GR activity are associated with radish salt tolerance, whereas no relationship with salinity was observed in superoxide dismutase(SOD), MDA and H2O2 content. | Rabab Sanoubar Antonio Cellini Giuseppe Gianfranco Francesco Spinelli | 2020 | Horticultural Plant Journal2020，6，1： | 5 |
| 3 | Survival after radiotherapy in gastric cancer: Systematic review and meta-analysis显示文摘 | Vincenzo Valentini Francesco Cellini Bruce D. Minsky Gian Carlo Mattiucci Mario Balducci Giuseppe D’Agostino Elisa D’Angelo Nicola Dinapoli Nicola Nicolotti Chiara Valentini Giuseppe La Torre | 2009 | Radiotherapy and Oncology2009，，2： | 4 |
| 4 | Pathways of flower infection and pollen-mediated dispersion of Pseudomonas syringae pv. actinidiae, the causal agent of kiwifruit bacterial canker显示文摘Flowers can provide a protected and nutrient-rich environment to the epiphytic microflora,thus representing a sensible entry point for pathogens such as Pseudomonas syringae pv.actinidiae(Psa).This bacterium can colonize both male and female Actinidia flowers,causing flower browning and fall,and systemic invasion of the host plant,eventually leading to its death.However,the process of flower colonization and penetration into the host tissues has not yet been fully elucidated.In addition,the presence of Psa in the pollen from infected flowers,and the role of pollination in the spread of Psa requires confirmation.The present study employed a Psa strain constitutively expressing the fluorescent GFPuv protein,to visualize in vivo flower colonization.Microscopy observations were performed by means of confocal laser scanning and wide-field fluorescent microscopy,and were coupled with the study of Psa population dynamics by quantitative PCR(q-PCR).The pathogen was shown to colonize stigmata,move along the stylar furrow,and penetrate the receptacles via the style or nectarhodes.Once the receptacle was invaded,the pathogen migrated along the flower pedicel and became systemic.Psa was also able to colonize the anthers epiphytically and endophytically.Infected male flowers produced contaminated pollen,which could transmit Psa to healthy plants.Finally,pollinators(Apis mellifera and Bombus terrestris)were studied in natural conditions,showing that,although they can be contaminated with Psa,the pathogen’s transmission via pollinators is contrasted by its short survival in the hive. | Irene Donati Antonio Cellini Giampaolo Buriani Sofia Mauri Callum Kay Gianni Tacconi Francesco Spinelli | 2018 | Horticulture Research2018，5，1： | 3 |
| 5 | Helicobacter pylori:A chameleon-like approach to life显示文摘Helicobacter pylori(H.pylori)is widely adaptable for colonization in human stomachs in more than half of the world’s population.The microorganism is characterized by an unusual capability of arranging itself in both genotypic and phenotypic ways.Stressing conditions,including antimicrobial agents in sub-inhibitory concentrations,facilitate entering the viable but nonculturable state in which bacterial cells acquire the coccoid form.This morphotype represents an important strategy for bacterial survival in unsuitable conditions and also allows escape from the immune system.H.pylori is capable of forming biofilm outside and inside the host.For the bacterial population,the sessile growth mode represents an ideal environment for gene rearrangement,as it allows the acquiring of important tools aimed to improve bacterial'fitness'and species preservation.Biofilm formation in H.pylori in the human host also leads to recalcitrance to antibiotic treatment,thus hampering eradication.These lifestyle changes of H.pylori allow for a'safe haven'for its survival and persistence according to different ecological niches,and strongly emphasize the need for careful H.pylori surveillance to improve management of the infection. | Luigina Cellini | 2014 | World Journal of Gastroenterology2014，20，19： | 3 |
| 6 | Activity of tea tree oil and nerolidol alone or in combination against Pediculus capitis (head lice) and its eggs显示文摘 | Emanuela Campli Soraya Bartolomeo Patricia Delli Pizzi Mara Giulio Rossella Grande Antonia Nostro Luigina Cellini | 2012 | Parasitology Research2012，，5： | 2 |
| 7 | Helicobacter pylori free‐living and biofilm modes of growth: behavior in response to different culture media显示文摘 | Lucinda J. Bessa Rossella Grande Donato DI Iorio Mara DI Giulio Emanuela DI Campli Luigina Cellini | 2012 | APMIS2012，，6： | 2 |
| 8 | Epidermal growth factor inthe topical treatment of herpetic corneal ulcers显示文摘 | Cellini M Baldi A Caramazza N | | 0，，： | 1 |
| 9 | Effect ofepidermal growth factor on small intestinal sodium/glucose cotransporter-1 expression in a rabbit model ofintrauterine growth retardation 显示文摘 | CELLINI C ’XU J BUCHMILIER-CRAIR T | 2005 | Journal of PediatricSurgery2005，40，12： | 1 |
| 10 | First - line therapy with thalidomide, dexamethasone and zoledronie acid decreases bone resorption markers in patients with multiple myeloma 显示文摘 | Tosi P Zamagni E Cellini C | 2006 | Eur J Haematol2006，76，5： | 1 |
| 11 | Dryness symptoms, diagnostic protocol and therapeutic management :A report on 1,200 patiens显示文摘 | Versura P Cellini M Torreggiani A | 2001 | Ophthalmol Res2001，33，4： | 1 |
| 12 | Effeet of epidermal growth factor infusion on fetal rabbit intrauterine growth retardation and small intestinal development显示文摘 | Cellini Xu J Arriaga A | 2004 | J Pediatr Surg2004，39，6： | 1 |
| 13 | Preoperative chemoradiation with cisplatin and 5-fiuorouracil for extraperitoneal T3 rectal cancer:Acute toxicity,tumor response,sphincter preservation显示文摘 | Vanlentini V Coco C Cellini N | 1999 | Int J Radiat Oncol Biol Phys1999，45，12： | 1 |
| 14 | Unintended effects and their detection in genetically modified crops显示文摘 | Cellini F Chesson A Colquhoun I | 2004 | Food Chem Toxicol2004，42，7： | 1 |
| 15 | Unintended effects and their detection in genetically modified crops显示文摘 | Cellini F Cheason A Colquhoun I | 2004 | Food and Chemical Toxicology2004，42，： | 1 |
| 16 | Dynamic colonization of Helicobacter pylori in human gastric mucosa显示文摘 | Cellini L Grande R Di Campli E | 2008 | Stand J Gastroenterol2008，43，2： | 1 |
| 17 | Postoperative pain control显示文摘 | Garimella V Cellini C | 2013 | Clin Colon Rectal Surg2013，26，3： | 1 |
| 18 | Dynamic R&D with spillovers:competition vs cooperation显示文摘 | CELLINI ROBERTO LAMBERTINI | 2009 | Gen- eral Information2009，33，3： | 1 |
| 19 | Advertising with Spillover Effects in a Differential Oligopoly Game With Differentiated Goods 显示文摘 | CELLINI R LAMBERTINI L | 2003 | European journal of operations research2003，11，4： | 1 |
| 20 | Aluminium-induced effects on growth,morphogenesis and oxidative stress reactions in in vitro cultures of quince显示文摘 | Schuch M W Cellini A Masia A | 2010 | Seientia Horticulturae2010，125，： | 1 |
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