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| 1 | Predictors of visual outcome in eyes with choroidal neovascularization secondary to age related macular degeneration treated with intravitreal bevacizumab monotherapy显示文摘AIM:To evaluate the predictors of visual improvement in eyes with naive choroidal neovascularization secondary to age-related macular degeneration (CNV -AMD) treated with intravitreal bevacizumab (IVB) monotherapy. METHODS:Fifty eyes with naive CNV-AMD with pretreatment best-corrected visual acuity (BCVA) better than 20/200 and treated with IVB monotherapy were evaluated. Several variables including age, sex, pre-treatment BCVA, CNV type and lesion size on fluorescein angiogram as well as SD-OCT parameters including pre-treatment central macular thickness (CMT), inner-segment/outer-segment (IS/OS) junction integrity, and external limiting membrane (ELM) integrity were analyzed to predict visual outcome.RESULTS:On univariate regression, pretreatment ELM damage was associated with less visual improvement after treatment (P =0.0145). However, ELM damage predicted only 10% of the visual outcome. On multivariate regression, pretreatment BCVA, IS/OS junction, and ELM integrity on SD-OCT were the significant predictors for the treatment effect and together predicted 37% of visual improvement. CONCLUSION:Pretreatment BCVA, ELM and IS/OS junction integrity on SD-OCT are of significant value inpredicting the visual improvement in naive wet AMD patients treated with IVB monotherapy. | Jay Chhablani Jae SukKim William R Freeman Igor Kozak Hai-Yan Wang Lingyun Cheng | 2013 | International Journal of Ophthalmology(English edition)2013，6，1： | 6 |
| 2 | Role of pancreatography in the endoscopic management of encapsulated pancreatic collections-review and new proposed classification显示文摘Pancreatic fluids collections are local complications related to acute or chronic pancreatitis and may require intervention when symptomatic and/or complicated.Within the last decade,endoscopic management of these collections via endoscopic ultrasound-guided transmural drainage has become the gold standard treatment for encapsulated pancreatic collections with high clinical success and lower morbidity compared to traditional surgery and percutaneous drainage.Proper understanding of anatomic landmarks,including assessment of the main pancreatic duct and any associated lesions–such as disruptions and strictures-are key to achieving clinical success,reducing the need for reintervention or recurrence,especially in cases with suspected disconnected pancreatic duct syndrome.Additionally,proper review of imaging and anatomic landmarks,including collection location,are pivotal to determine type and size of pancreatic stenting as well as approach using long-term transmural indwelling plastic stents.Pancreatography to adequately assess the main pancreatic duct may be performed by two methods:Either non-invasively using magnetic resonance cholangiopancreatography or endoscopically via retrograde cholangiopancreatography.Despite the critical need to understand anatomy via pancrea tography and assess the main pancreatic duct,a standardized approach or uniform assessment strategy has not been described in the literature.Therefore,the aim of this review was to clarify the role of pancreatography in the endoscopic management of encapsulated pancreatic collections and to propose a new classification system to aid in proper assessment and endoscopic treatment. | Igor Mendonca Proença Marcos Eduardo Lera dos Santos Diogo Turiani Hourneaux de Moura Igor Braga Ribeiro Sergio Eiji Matuguma Spencer Cheng Thomas R McCarty Epifanio Silvino do Monte Junior Paulo Sakai Eduardo Guimaraes Hourneaux de Moura | 2020 | World Journal of Gastroenterology2020，26，45： | 3 |
| 3 | Epidemiologyand eti- ology of childhood pneumonia 显示文摘 | Igor R Cynthia BP Zrinka B | 2008 | Bulletin of the World Health Organization2008，86，5： | 1 |
| 4 | Low-complexity image denoising based on statistical modeling of wavelet coefcients显示文摘 | MIHCAK M K IGOR K KANNAN R | 1999 | IEEE Signal Processing Letters1999，6，12： | 1 |
| 5 | Phase I-II Trial of Cetuximab, Capecitabine, Oxaliplatin, and Radiotherapy as Preoperative Treatment in Rectal Cancer显示文摘 | Claus R?del Dirk Arnold Matthias Hipp Torsten Liersch Kathrin Dellas Igors Iesalnieks Robert Michael Hermann Florian Lordick Axel Hinke Werner Hohenberger Rolf Sauer | 2008 | International Journal of Radiation Oncology Biology Physics2008，，4： | 1 |
| 6 | Low-grade fibromyxoid sarcoma of the liver: A case report显示文摘BACKGROUND Low grade fibromyxoid sarcoma(LGFMS)is a rare and benign mesenchymal tumor with indolent course,most commonly found in young or middle-aged men.The majority of the LGFMSs are located in the trunk and deep soft tissue of the lower extremities.They appear as well circumscribed,although not encapsulated,which often leads to incomplete surgical resection.Despite their seemingly benign appearance,these tumors have aggressive behavior with high metastatic and recurrence rates.Accurate histopathologic examination of the specimen and its immunohistochemical analysis are mandatory for a precise diagnosis.CASE SUMMARY We report a case of a 38 year-old-man who presented with jaundice and upper abdominal discomfort.Multi-detector computed tomography and magnetic resonance imaging showed a large left liver tumor mass,extending to the hepatoduodenal ligament.Left hepatectomy was performed with resection and reconstruction of hepatic artery and preservation of middle hepatic vein.Histopathologic examination confirmed the tumor being a low-grade fibromyxoid sarcoma.Three and a half years after surgery,the patient died after being diagnosed with spine metastasis.CONCLUSION Due to poor response to all modalities of adjuvant treatment,we consider that the focus of treatment should be on surgery as the only option for curing the disease. | Vladimir Dugalic Igor I Ignjatovic Jelena Djokic Kovac Nikola Ilic Jelena Sopta Slavenko R Ostojic Dragan Vasin Marko D Bogdanovic Igor Dumic Tamara Milovanovic | 2021 | World Journal of Clinical Cases2021，9，1： | 1 |
| 7 | Extention of the replicative life span of human diploid flbroblasts by inhibition of the p331NG1 candidate tumor suppressor显示文摘 | IGor G Karl R | 1997 | Mol Cell Biol1997，17，4： | 1 |
| 8 | Oral insulin enhances intestinal regrowth following massive small bowel resection in rat 显示文摘 | Igor Sukhotnik Naim Shehadeh Shamir R | 2005 | Dig Dis Sci2005，50，12： | 1 |
| 9 | Theoretical and empirical analysis of relief 显示文摘 | Marko R Igor K | 2003 | Machine Learning2003，，53： | 1 |
| 10 | Gap re- generation patterns in relationship to light heteroge- neity in two old-growth beech-fir forest reserves in South East Europe显示文摘 | DUSAN R STJEPAN M IGOR A | 2007 | Forestry2007，80，4： | 1 |
| 11 | Epidemiology and etiolo- gy of childhood pneumonia显示文摘 | Igor R Cynthia BP Zrinka B | 2008 | Bulletin of the World Heath Organization2008，86，5： | 1 |
| 12 | Globally evolutionarily stable portfolio hales显示文摘 | IGOR V EVSTIGNEEV T H KLAUS R | 2008 | Journal of Economic Theory2008，140，1： | 1 |
| 13 | Transforming growth factor beta 1 is a novel susceptibility gene for idiopathic pulmonary fibrosis 显示文摘 | IGOR R EUGENY E MIKHAIL I | 2013 | Spine2013，38，12： | 1 |
| 14 | Gap regeneration patterns in relationship to light heterogeneity in two old- growth beech - fir forest reserves in South East Europe显示文摘 | DUSAN R STJEPAN M IGOR A | 2007 | Forestry2007，80，4： | 1 |
| 15 | Gas-liquid annular flow un- der microgravity conditions: A temporal linear stability study显示文摘 | Igor Carron Frederick R Best | 1994 | International Journal of Multiphase Flow1994，20，6： | 1 |
| 16 | Cancer pain 显示文摘 | R Igor BM Pelv IC SR | 2000 | J Surg Oncol2000，75，4： | 1 |
| 17 | Molecular biomarkers in non-small-cell lung cancer: a retrospective analysis of data from the phase 3 FLEX study显示文摘 | Kenneth J O’Byrne Ulrich Gatzemeier Igor Bondarenko Carlos Barrios Corinna Eschbach Uwe M Martens Yevhen Hotko Cornelius Kortsik Luis Paz-Ares Jose R Pereira Joachim von Pawel Rodryg Ramlau Jae-Kyung Roh Chih-Teng Yu Christopher Stroh Ilhan Celik Armin Sc | 2011 | Lancet Oncology2011，，8： | 1 |
| 18 | Luminescent quantum dots in immunoassays显示文摘 | ELLEN R G IGOR L M HEDI M | 2006 | Anal Bioanal Chem2006，384，3： | 1 |
| 19 | Epidemiology and etiology of childhood Pneumonia 显示文摘 | Igor R Cynthia BP Zrinka B | 2008 | Bulletin of the World Health Organ- ization2008，86，5： | 1 |
| 20 | Surgical resection in the treatment of primary gastrointestinal Non - Hodgkin Is lymphoma: retrospective study 显示文摘 | Ivo R Jasminka KM Igor A | 2002 | Croat Med J2002，43，5： | 1 |
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