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| 1 | Open globe injury in Hospital Universiti Sains Malaysia- a 10-year review显示文摘AIM:To identify the aetiology of open globe injuries at Hospital Universiti Sains Malaysia over a period of 10y and the prognostic factors for visual outcome.METHODS:Retrospective review of medical records of open globe injury cases that presented from January2000 to December 2009.Classification of open globe injury was based on the Birmingham Eye Trauma Terminology(BETT).Records were obtained with hospital permission via the in-house electronic patient management system,and the case notes of all patients with a diagnosis of open globe injury were scrutinised.Patients with prior ocular trauma,pre-existing ocular conditions affecting the visual acuity,contrast sensitivity,central vision or corneal thickness,as well as those with a history of previous intraocular or refractive surgery were excluded.Analysis of data was with SPSS version20.0.Ordinal logistic regression analysis was used to examine the association between prognostic factors and visual outcome.RESULTS:This study involved 220 patients(n=222eyes).The most common place of injury was the home(51.8%),followed by the workplace(23.4%).Among children aged less than 16y of age,domestic-related injury was the predominant cause(54.6%),while in those aged 16y and above,occupational injuries were the most common cause(40.0%).Most eyes(76.5%)had an initial visual acuity worse than 3/60,and in half of these,the visual acuity improved.The visual outcome was found to be significantly associated with the initial visual acuity(P<0.005),posterior extent of wound(P<0.001),length of wound(P<0.001),presence of hyphaema(P<0.001)and presence of vitreous prolapse(P<0.005).CONCLUSION:The most common causes of open globe injury are domestic accidents and occupational injuries.Significant prognostic factors for final visual outcome in patients with open globe injury are initial visual acuity,posterior extent and length of wound,presence of hyphaema and presence of vitreous prolapse.Awareness of the factors predicting a poor visual outcome may be helpful during counselling of patients with open globe injuries. | Madhusudhan A/L Paramananda Evelyn-Tai Li Min Zamri Noordin Adil Hussein Wan-Hazabbah Wan Hitam | 2014 | International Journal of Ophthalmology(English edition)2014，7，3： | 9 |
| 2 | Comparison of peripapillary retinal nerve fiber layer thickness between myopia severity groups and controls显示文摘AIM: To compare the peripapillary retinal nerve fiber layer(RNFL) thickness measured via optical coherence tomography(OCT) between different groups of myopia severity and controls. METHODS: This was a prospective cross-sectional study. All subjects underwent a full ophthalmic examination, refraction, visual field analysis and A-scan biometry. Myopic patients were classified as low myopia(LM) [spherical equivalent(SE) from greater than-0.5 D, up to-3.0 D], moderate myopia(MM; SE greater than-3.0 D, up to-6.0 D) and high myopia(HM; SE greater than-6.0 D). The control group consisted of emmetropic(EM) patients(SE from +0.5 D to-0.5 D). A Zeiss Cirrus HD-OCT machine was used to measure the peripapillary RNFL thickness of both eyes of each subject. The mean peripapillary RNFL thickness between groups was compared using both analysis of variance and analysis of covariance.RESULTS: A total of 403 eyes of 403 subjects were included in this study. The mean age was 31.48±10.23 y. There were 180(44.7%) eyes with EM, 124(30.8%) with LM, 73(18.1%) with MM and 26(6.5%) with HM. All groups of myopia severity had a thinner average RNFL than the EM group, but after controlling for gender, age, and axial eye length, only the HM group differed significantly from the EM group(P=0.017). Likewise, the superior, inferior and nasal RNFL was thinner in all myopia groups compared to controls, but after controlling for confounders, only the inferior quadrant RNFL was significantly thinner in the HM group, when compared to the EM group(P=0.017). CONCLUSION: The average and inferior quadrant RNFL is thinner in highly myopic eyes compared to emmetropic eyes. Refractive status must be taken into consideration when interpreting the OCT of myopic patients, as RNFL thickness varies with the degree of myopia. | Evelyn Li Min Tai Jiunn Loong Ling Eng Hui Gan Hussein Adil Wan-Hiram Wan-Hazabbah | 2018 | International Journal of Ophthalmology(English edition)2018，11，2： | 7 |
| 3 | 精神病患者巨大眶内异物1例(英文)显示文摘患者,男,39岁,以右眼红、痛入院。他受到一个老者暗示将自己的右眼用木棒击伤。临床表现为右眼中度突出,完全性眼肌麻痹和严重眶周皮肤肿胀。眼科影像学表现为右眼眼窝蜂窝组织炎及眼下静脉血栓形成,两侧海绵窦综合征和海绵窦血栓。报告中无眼内及眶内异物。积极使用静脉抗生素,患者的病情并没有得到改善。在麻醉下检查发现在穹窿下有一个巨大的木质异物。异物去除及强力抗生素治疗下患者病情明显恢复。诊断中发现受伤原因可能是由这个精神病患者自我伤害引起。详细的病史、检查及合理的调查揭示其潜在的病因。敏锐的察觉及相关的临床发现与影像学研究在眶内异物及眶蜂窝组织炎处理中显得尤为有效的。及时诊断和治疗可能进一步减少患者的发病率或死亡率。 | Kok Foo Lee Siti Raihan Ismail Adil Hussein Mohtar Ibra-him Hasanah Che Ismail Win Mar@ Salmah Jalaluddin | 2010 | 国际眼科杂志2010，10，8： | 1 |
| 4 | Successful combined treatment in vernal shield ulcer 显示文摘 | Nurlaamiza Buang Shatriah Ismail Adil Hussein Mohtar Ibrahim Bakiala Shaharuddin | 2009 | Int J Ophtttatmol2009，9，9： | 1 |
| 5 | Ocular burns and related injuries due to fireworks during the Aidil Fitri celebration on the East Coast of the Peninsular Malaysia显示文摘 | Rasdi Abd Rashid Fatemeh Heidary Adil Hussein Wan Hazabbah Wan Hitam Rohana Abd Rashid Zulkifli Abd Ghani Nor Anita Che Omar Zuraidah Mustari Ismail Shatriah | 2010 | Burns2010，，1： | 1 |
| 6 | Antimicrobial susceptibility and multi-drug resistance of Salmonella enterica subspecies enterica serovars in Sudan显示文摘 | Mayha Mohammed Ali Nor Elmadiena Adil Ali Hussein Catherine Anne Muckle Linda Cole Elizabeth Wilkie Ketna Mistry Ann Perets | 2013 | Tropical Animal Health and Production2013，，5： | 1 |
| 7 | 支架植入和黏膜瓣保留对鼻内镜下泪囊鼻腔吻合术结果的影响(英文)显示文摘目的:研究支架植入术和黏膜瓣保留对鼻内镜下泪囊鼻腔吻合术结果的影响。 方法:回顾性分析2007~2011年间在马来西亚理科大学校医院所有行鼻内镜下泪囊鼻腔吻合术病例。25例鼻泪管阻塞患者参与此研究。术后1,6,12mo,通过泪溢症状缓解、泪道冲洗通畅、鼻内窥镜下造瘘口通畅三个标准来评估手术结果。术后1a内三个标准都通过时手术才算成功。采用多元逻辑回归分析研究支架植入和黏膜瓣保留与手术成功率之间的关系。 结果:25例患者中13例采用支架植入术,此方法同样适用于黏膜瓣保留。术后1a内鼻内镜下泪囊鼻腔吻合术的成功率是64%。支架植入与否与术后成功率之间的无关联(P=0.694),然而黏膜瓣保留能有效提高手术成功率(调整后OR=7.926;95%CI:1.172~53.620, P=0.034)。术后主要并发症为局部粘连,50%的病例有此症状表现。支架植入或黏膜瓣保留与并发症之间无关联。 结论:在鼻泪管阻塞治疗中,鼻内镜下泪囊鼻腔吻合术成功率与黏膜瓣保留有着重大的关系,而与支架植入无关。支架植入和黏膜瓣保留与并发症发生率无关。 | Evelyn Tai Li Min Jessica Mani Penny Tevaraj Wan Hazabbah Wan Hitam Ramiza Ramza Baharudin Abdullah Adil Hussein | 2014 | 国际眼科杂志2014，14，3： | 0 |
| 8 | 晶状体异物所致单眼轻度前葡萄膜炎1例(英文)显示文摘报道1例晶状体内异物所致单眼轻度前葡萄膜炎。患者,男,25岁,以'右眼持续畏光,流泪2mo'主诉就诊,无痛性视力下降。之前有金属物体敲击史。眼科检查显示轻度前葡萄膜炎,晶状体内存留异物,无眼部充血。CT检查证实球内异物。这种情况容易被漏诊和误诊,详细的病史采集和临床检查对避免误诊至关重要。 | Khairy-Shamel Sonny Teo Shatriah Ismail Adil Hussein Mohtar Ibrahim Zunaina Embong Bakiah Shaharuddin | 2009 | 国际眼科杂志2009，9，6： | 0 |
| 9 | 联合疗法成功治疗春季盾形溃疡(英文)显示文摘21岁和11岁两位患者患严重的持续性盾形溃疡,包括局部激素、肥大细胞稳定剂及抗组胺药的药物治疗均无效。两者均接受溃疡的外科清创,上睑板下注射曲安奈德,局部用0.5g/L环孢霉素A和0.25g/L富马酸酮替芬治疗。3wk后溃疡愈合。2mo后两位患者停用局部环孢霉素A。患者症状缓解,6mo没有复发。联合溃疡的外科清创,上睑板下注射曲安奈德,局部用0.5g/L环孢霉素A和0.25g/L富马酸酮替芬是治疗重度春季盾形溃疡的有效方案。 | Nurhamiza Buang Shatriah Ismail Adil Hussein Mohtar Ibrahim Bakiah Shaharuddin | 2009 | 国际眼科杂志2009，9，9： | 0 |
| 10 | Orbital apex syndrome after tooth extraction in an immunocompromised patient显示文摘A 60 year-old man presented with acute on set of left eye proptosis and ptosis.It was associated with poor vision,eye pain and restriction of eye movement of the same eye after 5 hours post left upper molar tooth extraction.The visual acuity in the left eye was hand movement.There was severe ptosis and proptosis of the left eye.The conjunctiva was chemotic with quite anterior chamber.The pupil was mid dilated and sluggished to light.The ocular movement was restricted in all directions.Fundoscopy of the left eye revealed features of central retinal artery occlusion with hyperaemic disc and subretinal exudates at posterior pole.The right eye appeared normal.Urgent MRI brain and orbit revealed severe left paranasal sinusitis with anterior displacement of the left globe and presence orbital abscess.Patient was managed with Otorhinolaryngology and Neuro-surgery teams.He underwent emergency transnasal drainage of abscess.Histopathological examination of unhealthy sinus mucosa showed evidence of fungal infection.However,the culture and sensitivity result was inconclusive.Patient was treated with amphotericin B,ceftriaxone,amoxicillin clavulanate and metronidazole.Patient was detected to have high blood sugar level and was managed accordingly.The proptosis improved with treatment.However,his vision,ptosis and ophthalmoplegia remained static.Assessing the immunocompromised status is important for the management of patient presented as acute orbital apex syndrome to avoid fatal outcome. | Suresh Subramaniam Cheong Min Tet Wan Hazabbah Wan Hitam Adil Hussein Shamim Ahmed Khan Hillol Kanti Pal Zunaina Embong | 2011 | International Journal of Ophthalmology(English edition)2011，4，1： | 0 |
| 11 | Non-arteritic anterior ischaemic optic neuropathy in Malaysia: a 5 years review显示文摘AIM: To evaluate the clinical presentations and visual outcomes of non-arteritic anterior ischaemic optic neuropathy (NAION).METHODS: A retrospective study was conducted involving 18 consecutive patients (20 eyes) with NAION attending Hospital Universiti Sains Malaysia from January 2005 until December 2009.RESULTS: Most patients were Malay (94.4%),and followed by Chinese (5.6 %).The female-to-male ratio was 3.5:1.The age of patients ranged from 36 to 85 years (mean,57.1 years).The main risk factors in systemic diseases were hypertension (55.5%),diabetes mellitus (44.4%),and ischaemic heart disease (11.1%).Most patients (77.8%) presented with acute loss of vision while gradual onset was in 22.3% of cases.Majority had visual acuity worse than 1/60 (80%).The most common fundoscopic findings were peripapillary splinter haemorrhage (90%),sectorial swollen optic disc (60%) and hyperemic disc (60%).During follow up,20% of the patients showed stabilization in visual acuity,and 80% showed worsening of vision.CONCLUSION: Majority of patients with NAION presented with acute poor vision involving middle-aged and elderly individuals.Hypertension and diabetes mellitus were among the main risk factors involved.NAION can lead to permanent visual loss despite treatment. | Abdulrahman Bawazir Reza Gharebaghi Adil Hussein Wan Hazabbah Wan Hitam | 2011 | International Journal of Ophthalmology(English edition)2011，4，3： | 0 |
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