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| 1 | Piper sarmentosum as an antioxidant on oxidative stress in human umbilical vein endothelial cells induced by hydrogen peroxide显示文摘Endothelial cell death due to increased reactive oxygen species(ROS) may contribute to the initial endothelial injury,which promotes atherosclerotic lesion formation.Piper sarmentosum(PS),a natural product,has been shown to have an antioxidant property,which is hypothesized to inhibit production of ROS and prevent cell injury.Thus,the present study was designed to determine the effects of PS on the hydrogen peroxide(H2O2)-induced oxidative cell damage in cultured human umbilical vein endothelial cells(HUVECs).In this experiment,HUVECs were obtained by collagenase perfusion of the large vein in the umbilical cord and cultured in medium M200 supplemented with low serum growth supplementation(LSGS).HUVECs were treated with various concentrations of H2O2(0-1000 μmol/L) and it was observed that 180 μmol/L H2O2 reduced cell viability by 50% as denoted by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide(MTT) assay.Using the above concentration as the positive control,the H2O2-induced HUVECs were concomitantly treated with various concentrations(100,150,250 and 300 μg/ml) of three different extracts(aqueous,methanol and hexane) of PS.Malondialdehyde(MDA),superoxide dismutase(SOD),catalase(CAT) and glutathione peroxidase(GPX) levels showed a significant increase(P<0.05) in HUVECs compared to the negative control.However,PS extracts showed a protective effect on HUVECs from H2O2-induced cell apoptosis with a significant reduction in MDA,SOD,CAT and GPX levels(P<0.05).Furthermore,PS had exhibited ferric reducing antioxidant power with its high phenolic content.Hence,it was concluded that PS plays a beneficial role in reducing oxidative stress in H2O2-induced HUVECs. | Abdul Hamid HAFIZAH Zakaria ZAITON Amom ZULKHAIRI Adenan MOHD ILHAM Megat Mohd Nordin NOR ANITA Abdullah Mahdy ZALEHA | 2010 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2010，11，5： | 13 |
| 2 | Beamforming techniques for massive MIMO systems in 5G:overview,classification,and trends for future research显示文摘Massive multiple-input multiple-output(MIMO) systems combined with beamforming antenna array technologies are expected to play a key role in next-generation wireless communication systems(5G), which will be deployed in 2020 and beyond. The main objective of this review paper is to discuss the state-of-the-art research on the most favourable types of beamforming techniques that can be deployed in massive MIMO systems and to clarify the importance of beamforming techniques in massive MIMO systems for eliminating and resolving the many technical hitches that massive MIMO system implementation faces. Classifications of optimal beamforming techniques that are used in wireless communication systems are reviewed in detail to determine which techniques are more suitable for deployment in massive MIMO systems to improve system throughput and reduce intra-and inter-cell interference. To overcome the limitations in the literature, we have suggested an optimal beamforming technique that can provide the highest performance in massive MIMO systems, satisfying the requirements of next-generation wireless communication systems. | Ehab ALI Mahamod ISMAIL Rosdiadee NORDIN Nor Fadzilah ABDULAH | 2017 | Frontiers of Information Technology & Electronic Engineering2017，18，6： | 8 |
| 3 | Impact of land uses on water quality in Malaysia: a review显示文摘Land use changes in urbanization,industrialization,and agricultural processes will continue to have negative impacts on water quality at all scales.The impact of land use changes on water quality is generally studied by analyzing the relationships between land use and water quality indicators.Therefore,the purpose of this research was to review and analyze the main relationships between land use and water quality,as well as to visualize the major sources and processes of water quality pollution in Malaysia.To achieve our goal,we evaluated the significance of both land use and water quality attributes used in the past studies and correlated them to understand their relationship from another angle of view.The results revealed that 87%of the reviewed studies indicated urban land use as a major source of water pollution,while 82%indicated agricultural land use,77%indicated forest land use,and 44%indicated other land uses.However,the results of correlation analysis showed that agricultural and forest-related activities more affected water quality through their significant positive correlation with physical and chemical indicators of water quality,while urban development activities had a greater impact on water quality through altering hydrological processes such as runoff and erosion.These findings would provide decision-makers with useful information for managing water pollution processes rather than sources only. | Moriken Camara Nor Rohaizah Jamil Ahmad Fikri Bin Abdullah | 2019 | Ecological Processes2019，8，1： | 8 |
| 4 | Effect of TGF-131 antisense oligodeoxynucleotide on renal function in chronic renal failure rats显示文摘目的:学习是调查转变生长因素( TGF )贝它 1 反的有效性的礼品的目的在改善察觉到 oligodeoxynucleotides ( ODN )在有 导致puromycin 的长期的肾衰竭( CRF )的老鼠的败坏的肾功能 .Methods :盐,嘌呤霉素,puromycin+TGF贝它 1 反感觉 ODN 或 puromycin+scrambled ODN 予被以单方地 nephrecto-mized 老鼠。肾的血液动力学、分泌的大小在经历了外科的 procedure.Results 的使麻木的老鼠被拿:在 CRF 老鼠,在肾的血流( RBF )有显著减小,这被观察, glomerular 率( GFR ),严重蛋白尿,并且几乎6褶层在控制老鼠作为与那相比增加了钠( FE Na^+)的部分排泄(所有 P < 0.05 )。在 CRF 老鼠,有 1 反察觉到的 TGF 贝它的处理,然而并非爬的 ODN,显著地稀释了 RBF, GFR,和蛋白尿的减小并且显著地阻止了 FE Na^+ 的增加,这进一步被观察(所有 P < 0.05 ) 。另外,在 CRF 的肾的肥大组织(P < 0.05 对非肾的失败控制) 是有 TGF-1 反感觉 ODN 的显著地稀释的术后疗法(P < 0.05 ) 。焦点的部分肾小球硬化症在未经治疗、爬的对待 ODN 的 CRF 组仅仅是明显的。这研究的有趣的观察在 CRF 老鼠是那,尽管有显著 attenuating 和TGF贝它的预防效果败坏的肾的功能上的 1 反感觉 ODN ,反感觉处理没在TGF贝它的肾的表示引起任何显著变化 1 在蛋白质 level.Conclusion :一起,获得的数据建议 1 反感觉 ODN 拥有的那TGF贝它在 导致puromycin 的长期的肾衰竭的有益的效果并且在形态学的恶化和处于这个病理学的状态的损害肾的功能部分地依赖于TGF贝它的行动 1 在肾以内。 | Law Chung HIONG Kiew Lik VOON Nor Azizan ABDULLAH Munavvar A SATTAR Nazarina Abdul RAHMAN Abdul Hye KHAN4, Edward James JOHNS | 2008 | Acta Pharmacologica Sinica2008，29，4： | 7 |
| 5 | Nasal metastases from renal cell carcinoma are associated with Memorial Sloan-Kettering Cancer Center poor-prognosis classification显示文摘Unusual sites of metastases are recognized in patients with renal cell carcinoma (RCC). However, the prognostic implications of these sites are not well understood. We used the Memorial Sloan-Kettering Cancer Center (MSKCC) risk classification for metastatic RCC to evaluate 912 consecutive patients with RCC managed at the Singapore General Hospital between 1990 and 2009. Among these patients, 301 had metastases either at diagnosis or during the course of illness. Nasal metastases, all arising from clear cell RCC, were identified histologically in 4 patients (1.3% of those with metastasis). All 4 patients were classified as MSKCC poor prognosis by current risk criteria. Nasal metastases were significantly associated with lung and bone metastases. The frequency of nasal metastases in patients with metastatic RCC is about 1%, occurring predominantly in patients with clear cell RCC. Nasal metastases are associated with poor prognosis as estimated by the MSKCC risk classification, with attendant implications for selection of targeted therapy, and are usually associated with multi-organ dissemination, including concurrent lung and bone involvement. | Caroline Victoria Choong Tiffany Tang Wen Yee Chay Christopher Goh Miah Hiang Tay Nor Azhari Mohd Zam Puay Hoon Tan Min-Han Tan | 2011 | Chinese Journal of Cancer2011，30，2： | 6 |
| 6 | Characterization and Activity of Cr, Cu and Ga Modified ZSM-5 for Direct Conversion of Methane to Liquid Hydrocarbons显示文摘Direct conversion of methane using a metal-loaded ZSM-5 zeolite prepared via acidic ion exchange was investigated to elucidate the roles of metal and acidity in the formation of liquid hydrocarbons. ZSM-5 (SiO2/Al2O3=30) was loaded with different metals (Cr, Cu and Ga) according to the acidic ion-exchange method to produce metal-loaded ZSM-5 zeolite catalysts. XRD, NMR, FT-IR and N2 adsorption analyses indicated that Cr and Ga species managed to occupy the aluminum positions in the ZSM-5 framework. In addition, Cr species were deposited in the pores of the structure. However, Cu oxides were deposited on the surface and in the mesopores of the ZSM-5 zeolite. An acidity study using TPD-NH3, FT-IR, and IR-pyridine analyses revealed that the total number of acid sites and the strengths of the Bronsted and Lewis acid sites were significantly different after the acidic ion exchange treatment.Cu loaded HZSM-5 is a potential catalyst for direct conversion of methane to liquid hydrocarbons. The successful production of gasoline via the direct conversion of methane depends on the amount of aluminum in the zeolite framework and the strength of the Bronsted acid sites. | Nor Aishah Saidina Amin Didi Dwi Anggoro | 2003 | Journal of Natural Gas Chemistry2003，12，2： | 6 |
| 7 | Effect of intermetallic compounds on the fracture behavior of dissimilar friction stir welding joints of Mg and Al alloys显示文摘Joining Mg to Al is challenging because of the deterioration of mechanical properties caused by the formation of intermetallic compounds(IMCs) at the Mg/Al interface. This study aims to improve the mechanical properties of welded samples by preventing the fracture location at the Mg/Al interface. Friction stir welding was performed to join Mg to Al at different rotational and travel speeds. The microstructure of the welded samples showed the IMCs layers containing Al12Mg17(γ) and Al3Mg2(β) at the welding zone with a thickness(< 3.5 μm). Mechanical properties were mainly affected by the thickness of the IMCs, which was governed by welding parameters. The highest tensile strength was obtained at 600 r/min and 40 mm/min with a welding efficiency of 80%. The specimens could fracture along the boundary at the thermo-mechanically affected zone in the Mg side of the welded joint. | Amir Hossein Baghdadi Zainuddin Sajuri Nor Fazilah Mohamad Selamat Mohd Zaidi Omar Yukio Miyashita Amir Hossein Kokabi | 2019 | International Journal of Minerals,Metallurgy and Materials2019，26，10： | 5 |
| 8 | Screening of MgO- and CeO_2-Based Catalysts for Carbon Dioxide Oxidative Coupling of Methane to C_(2+) Hydrocarbons显示文摘The catalyst screening tests for carbon dioxide oxidative coupling of methane (CO2-OCM)have been investigated over ternary and binary metal oxide catalysts.The catalysts are prepared by doping MgO-and CeO2-based solids with oxides from alkali(Li2O),alkaline earth (CaO),and transition metal groups (WO3 or MnO).The presence of the peroxide (O2^2-)active sites on the Li2O2,revealed by Raman spectroscopy,may be the key factor in the enhanced performance of some of the Li2O/MgO catalysts.The high reducibility of the CeO2 catalyst,an important factor in the CO2-OCM catalyst activity,may be enhanced by the presence of manganese oxide species. The manganese oxide species increases oxygen mobitity and oxygen vacancies in the CeO2 catalyst.raman and Fourier Transform Infra Red (FT-IR)spectroscopies revealed the presence of lattice vibrations of metal-oxygen bondings and active sites in which the peaks carresponding to the buld crystalline structures of Li2O,CaO,WO2 and MnO are detected.The performance of 5%MnO/15%CaO/CeO2 catalyst is the most potential among the CeO2-based catalysts,although lower than the 2%Li2O/MgO catalyst.The 2%Li2O/MgO catalyst showed the most promising C2+hydrocarbons selectivity and yield at 98.0%and 5.7%,respectively. | Istadi Nor Aishah Saidina Amin | 2004 | Journal of Natural Gas Chemistry2004，13，1： | 5 |
| 9 | 一种使用静态分析和遗传搜索在Android恶意软件检测中搜索最优特征的方法(英文)显示文摘移动设备制造商在全球范围内快速开发各种Android版本。同时,网络罪犯也在实施各种恶意行为,例如跟踪用户活动、窃取个人数据以及实施银行诈骗。由于在日常生活中使用Android进行重要通信的人群数量庞大,这些网络罪犯从中获得了巨大非法收益。为此,安全从业者通过静态和动态分析对恶意软件进行识别。静态分析具有整体代码覆盖、低资源消耗和快速处理的优势。然而,静态分析需要最少量的特征才能对恶意软件进行有效分类。因此,我们采用基于遗传算法(GA)的遗传搜索(GS)在106个字符串中选择特征。为评估由GS确定的最佳特征,我们使用了5种机器学习分类器,分别是Na?ve Bayes(NB)、功能树(FT)、J48、随机森林(RF)和多层感知器(MLP)。在这5种分类器中,FT仅使用6种特征,获得最高准确度(95%)和最高真正率(TPR)(96.7%)。 | Ahmad FIRDAUS Nor Badrul ANUAR Ahmad KARIM Mohd Faizal Ab RAZAK | 2018 | Frontiers of Information Technology & Electronic Engineering2018，19，6： | 5 |
| 10 | 容碳的SiW_(20)-Al/Zr_(10)催化剂用于甘油脱水制丙烯醛(英文)显示文摘将一系列负载型硅钨酸催化剂用于甘油脱水制丙烯醛反应中.表征结果表明,最终所得催化剂具有高的热稳定性、大的孔径、强的L酸位和大的比表面积.X射线光电子能谱中清晰地出现归属于W(W 4f=35.8 eV),Al(Al 2p=74.9 eV)和Zr(Zr 3d=182.8 eV)元素的谱峰.在SiW_(20)-Al/Zr_(10)催化剂上丙烯醛选择性最高,为87.3%,此时甘油转化率为97%.由于高浓度L酸位的存在,显著降低了催化剂表面积碳量,因而该催化剂即使反应40 h之后仍具有较高地催化生成丙烯醛的活性和选择性.响应面方法表明,在以下优化条件下反应甘油转化率和丙烯醛选择性分别达87.7%和97.0%:催化剂用量0.5wt%,进料甘油浓度10 wt%,反应温度300 ℃.传质限制评估结果显示,当颗粒尺寸d_P<20μm时,反应不存在内外扩散限制.综上可见。 | Amin Talebian-Kiakalaieh Nor Aishah Saidina Amin | 2017 | Chinese Journal of Catalysis2017，38，10： | 4 |
| 11 | Distribution of Chironomidae (Insecta: Diptera) in polluted rivers of the Juru River Basin, Penang, Malaysia显示文摘The influence of physical and chemical parameters on the abundance and diversity of chironomids was studied in six rivers with moderate to highly polluted water in the Juru River Basin. The rivers: Ceruk Tok Kun (CTKR) as reference site, and polluted rivers of Pasir (PR), Juru (JR), Permatang Rawa (PRR), Ara (AR) and Kilang Ubi (KUR) were sampled over a period of five months (November 2007-March 2008). Nine chirnomid species: Chironimus kiiensis, C. javanus, Polypedilum trigonus, Microchironomus sp., Dicrotendipes sp., Tanytarsus formosanus, Clinotanypus sp., Tanypus punctipennis and Fittkauimyia sp. were identified. Assessment of their relationships with several environmental parameters was performed using the canonical correspondence analysis (CCA). Tanytarsus formosanus was the most dominant in the relatively clean CTKR and moderately polluted JR with mean densities of 19.66 and 25.32 m 2 , respectively while C. kiiensis was abundant in more polluted rivers. Tanytarsus formosanus, Dicrotendipes sp. and Microchironomus sp. were grouped under moderate to high water temperature, total organic matter (TOM), total suspended solids (TSS), velocity, pH, phosphates and sulphates. However, Tanypus punctipennis, Fittkauimyia sp., and Clinotanypus sp. were associated with high contents of river sediment such as TOM, Zn and Mn and water ammonium-N and nitrate-N and they were associated with higher dissolved oxygen (DO) content in the water. Chironomus kiiensis, C. javanus and P. trigonus showed positive relationships with TOM, ammonium-N and nitrate-N as well as trace metals of Zn, Cu and Mn. These three species could be considered as tolerant species since they have the ability to survive in extreme environmental conditions with low DO and high concentrations of pollutants. Based on the water parameter scores in all rivers, the highest diversity of chironomid larvae was reported in CTKR. With higher concentrations of organic and/or inorganic pollutants as reported in PPR, KUR and AR, the chironomid larval diversity decreased, and the abundance of tolerant species, mainly Chironomus spp., increased. | Salman A. Al-Shami Che Salmah Md Rawi Abu HassanAhmad Siti Azizah Mohd Nor | 2010 | Journal of Environmental Sciences2010，22，11： | 4 |
| 12 | Genetic barriers in transplantation medicine显示文摘The successful of transplantation is determined by the shared human leukocyte antigens(HLAs) and ABO blood group antigens between donor and recipient. In recent years, killer cell receptor [i.e., killer cell immunoglobulinlike receptor(KIR)] and major histocompatibility complex(MHC) class I chain-related gene molecule(i.e., MICA) were also reported as important determinants of transplant compatibility. At present, several different genotyping techniques(e.g., sequence specific primer and sequence based typing) can be used to characterize blood group, HLA, MICA and KIR and loci. These molecular techniques have several advantages because they do not depend on the availability of anti-sera, cellular expression and have greater specificity and accuracy compared with the antibody-antigen based typing. Nonetheless, these molecular techniques have limited capability to capture increasing number of markers which have been demonstrated to determine donor and recipient compatibility. It is now possible to genotype multiple markers and to the extent of a complete sequencing of the human genome using next generation sequencer(NGS). This high throughput genotyping platform has been tested for HLA, and it is expected that NGS will be used to simultaneously genotype a large number of clinically relevant transplantation genes in near future. This is not far from reality due to the bioinformatics support given by the immunogenetics community and the rigorous improvement in NGS methodology. In addition, new developments in immune tolerance based therapy, donor recruitment strategies and bioengineering are expected to provide significant advances in the field of transplantation medicine. | Hisham A Edinur Siti M Manaf Nor F Che Mat | 2016 | World Journal of Transplantation2016，6，3： | 4 |
| 13 | 两性霉素B角膜基质内注射成功治疗真菌性角膜炎1例(英文)显示文摘目的:报告1例使用5mg/L两性霉素成功治疗难治性真菌性角膜炎的病例。方法:病例报告。结果:女性患者1例,48岁,以右眼红1wk,伴视力下降和角膜混浊2d入院。否认有外伤或异物史。检查发现:右眼视力:6/12,针孔视力:6/18。注射结膜前使眼分泌物保持最少。角膜旁中央区有一全层基质脓肿-形态不规则且伴有卫星病灶及羽状边缘,不伴有上皮缺损,有前房积脓液平。左眼正常。诊断为真菌性角膜炎。尽管在此前患者经历了3wk的局部两性霉素B点眼(1次/2h),那他霉素眼液点眼(1次/4h),但并无病情恢复的迹象。相反12点出现了一个新的更大的基质脓肿病灶。我们应用5mg/L两性霉素B角膜基质注射联合穿透性角膜移植术治疗后溃疡面积明显减少,前房积脓完全消失,没有毒性反应发生。患者干预后2mo视力恢复了正常视力(6/6)。结论:使用两性霉素B5mg/L基质内注射,使用过程安全有效,是一种治疗难治性真菌性角膜炎的理想方法。 | Yanti Muslikhan Nor Sharina Yusof Khairy Shamel Sonny Teo Azhany Y aakob Mohtar Ibrahim | 2010 | 国际眼科杂志2010，10，11： | 4 |
| 14 | Outcome of trabeculectomy in hospital Melaka,Malaysia显示文摘AIM:To study the success and outcome of trabeculectomy in Hospital Melaka.· METHODS:Medical records of all patients who underwent trabeculectomy between January 1,2007 and October 31,2010 whom were followed up for at least 6 months postoperatively in Hospital Melaka were retrospectively reviewed.· RESULTS:A total number of 117 eyes of 91 patients with the age range between 12 to 84 years underwent primary trabeculectomy(n =20,17.1%),combine trabeculectomy with cataract surgery(n =90,76.9%),repeat trabeculectomy(n=5,4.3%),and combine repeat trabeculectomy with cataract surgery(n =2,1.7%).The disease spectrum includes primary open-angle glaucoma(POAG)(54 patients,59.3%),priamry angle-closure glaucoma(PACG)(14 patients,15.4%),secondary glaucomas(19 patients,20.9%) and juvenile glaucomas(4 patients,4.4%).Preoperative mean intraocular pressure(IOP) was(24.69±8.67)mmHg as compared to postoperative mean IOP of(15.81±6.66)mmHg,(15.07±4.72)mmHg and(15.68±3.65)mmHg at 6-month,12-month and 24-month respectively.Eighty-two point one percent of eyes(n =96) achieved complete success(CS),12.8%(n =15) with qualified success(QS) and only 5.1%(n = 6) failed at 6 month with two of them warrant other filtering surgery.At twelve months,trabeculectomy with CS was 71.6%(n =63),QS in 22.7%(n =20) and failure in 5.7%(n = 5).Sixty-seven point five percent(n =27) attained CS,20.0%(n =8) with QS while 12.5%(n =5) failed at 24 month postoperative.· CONCLUSION:As the understanding of the lower the IOP,the better the patients retaining the visual function,trabeculectomy is significantly a choice of treatment in uncontrolled glaucoma.This study concluded that trabeculectomy performed in Hospital Melaka has produced significant success as compared to other studies. | Moon Heng Hah Raja Norliza Raja Omar Juliana Jalaluddin Nor Fadzillah Abd Jalil Anusiah Selvathurai | 2012 | International Journal of Ophthalmology(English edition)2012，5，3： | 4 |
| 15 | Review:Botnet detection techniques: review, future trends, and issue显示文摘In recent years, the Internet has enabled access to widespread remote services in the distributed computing environment; however, integrity of data transmission in the distributed computing platform is hindered by a number of security issues. For instance, the botnet phenomenon is a prominent threat to Internet security, including the threat of malicious codes. The botnet phenomenon supports a wide range of criminal activities, including distributed denial of service(DDoS) attacks, click fraud, phishing, malware distribution, spam emails, and building machines for illegitimate exchange of information/materials. Therefore, it is imperative to design and develop a robust mechanism for improving the botnet detection, analysis, and removal process. Currently, botnet detection techniques have been reviewed in different ways; however, such studies are limited in scope and lack discussions on the latest botnet detection techniques. This paper presents a comprehensive review of the latest state-of-the-art techniques for botnet detection and figures out the trends of previous and current research. It provides a thematic taxonomy for the classification of botnet detection techniques and highlights the implications and critical aspects by qualitatively analyzing such techniques. Related to our comprehensive review, we highlight future directions for improving the schemes that broadly span the entire botnet detection research field and identify the persistent and prominent research challenges that remain open. | Ahmad KARIM Rosli Bin SALLEH Muhammad SHIRAZ Syed Adeel Ali SHAH Irfan AWAN Nor Badrul ANUAR | 2014 | Journal of Zhejiang University-Science C(Computers and Electronics)2014，15，11： | 4 |
| 16 | Taurine protects against retinal and optic nerve damage induced by endothelin-1 in rats via antioxidant effects显示文摘Endothelin-1(ET-1), a potent vasoconstrictor, is involved in retinal vascular dysregulation and oxidative stress in glaucomatous eyes. Taurine(TAU), a naturally occurring free amino acid, is known for its neuroprotective and antioxidant properties. Hence, we evaluated its neuroprotective properties against ET-1 induced retinal and optic nerve damage. ET-1 was administered intravitreally to Sprague-Dawley rats and TAU was injected as pre-, co-or post-treatment. Animals were euthanized seven days post TAU injection. Retinae and optic nerve were examined for morphology, and were also processed for caspase-3 immunostaining. Retinal redox status was estimated by measuring retinal superoxide dismutase, catalase, glutathione, and malondialdehyde levels using enzyme-linked immuosorbent assay. Histopathological examination showed significantly improved retinal and optic nerve morphology in TAU-treated groups. Morphometric examination showed that TAU pre-treatment provided marked protection against ET-1 induced damage to retina and optic nerve. In accordance with the morphological observations, immunostaining for caspase showed a significantly lesser number of apoptotic retinal cells in the TAU pre-treatment group. The retinal oxidative stress was reduced in all TAU-treated groups, and particularly in the pre-treatment group. The findings suggest that treatment with TAU, particularly pre-treatment, prevents apoptosis of retinal cells induced by ET-1 and hence prevents the changes in the morphology of retina and optic nerve. The protective effect of TAU against ET-1 induced retinal and optic nerve damage is associated with reduced retinal oxidative stress. | Natasha Najwa Nor Arfuzir Renu Agarwal Igor Iezhitsa Puneet Agarwal Sabrilhakim Sidek Nafeeza Mohd Ismail | 2018 | Neural Regeneration Research2018，13，11： | 3 |
| 17 | Glutathione (GSH) improves sperm quality and testicular morphology in streptozotocin-induced diabetic mice显示文摘Diabetes mellitus(DM)is known to cause reproductive impairment.In men,it has been linked to altered sperm quality and testicular damage.Oxidative stress(OS)plays a pivotal role in the development of DM complications.Glutathione(GSH)is a part of a nonenzymatic antioxidant defense system that protects lipid,protein,and nucleic acids from oxidative damage.However,the protective effects of exogenous GSH on the male reproductive system have not been comprehensively examined.This study determined the impact of GSH supplementation in ameliorating the adverse effect of type 1 DM on sperm quality and the seminiferous tubules of diabetic C57BL/6NTac mice.GSH at the doses of 15 mg kg^(-1)and 30 mg kg^(-1)was given intraperitoneally to mice weekly for 6 consecutive weeks.The mice were then weighed,euthanized,and had their reproductive organs excised.The diabetic(D Group)showed significant impairment of sperm quality and testicular histology compared with the nondiabetic(ND Group).Diameters of the seminiferous lumen in diabetic mice treated with 15 mg kg^(-1) GSH(DGSH15)were decreased compared with the D Group.Sperm motility was also significantly increased in the DGSH15 Group.Improvement in testicular morphology might be an early indication of the protective roles played by the exogenous GSH in protecting sperm quality from effects of untreated type 1 DM or diabetic complications.Further investigation using different doses and different routes of GSH is necessary to confirm this suggestion. | Fathiah Abdullah Mohamed Noor Khan Nor-Ashikin Renu Agarwal Yuhaniza Shafinie Kamsani Mastura Abd Malek Nor Salmah Bakar Aqila-Akmal Mohammad Kamal Mimi-Sophia Sarbandi Nor-Shahida Abdul Rahman Nurul Huda Musa | 2021 | Asian Journal of Andrology2021，23，3： | 3 |
| 18 | 非霍奇金淋巴瘤转移性眼浸润放射治疗后视网膜色素上皮脱离1例显示文摘患者,女,32岁,被诊断为纵隔未分化大细胞非霍奇金淋巴瘤,化疗后3a出现双眼悬浮物和右眼视力下降。眼科检查发现带有多发深在的左眼脉络膜病变的双侧全葡萄膜炎。眼窝电脑断层扫描显示两侧球后视神经部分加强和大块的视神经鞘。该患者接受眼窝受累区域放射治疗,累积剂量为30戈瑞。放射治疗8mo后,发展为黄斑部视网膜色素上皮脱离和右侧颞上和鼻下区眼底的深脉络膜视网膜变性。在脉络膜视网膜变性区边缘有玻璃体视网膜牵引迹象,从而路障激光在受累眼睛进行。双眼视力仍然6/6。视网膜色素上皮脱离可能是放射治疗非霍奇金淋巴瘤眼内转移时的并发症。至关重要的是提醒了眼科医生这个罕见的并发症。 | Muzaliha Mohd Nor Roslinah Muji Zunaina Embong Bakiah Shaharuddin Shatriah Ismail | 2010 | 国际眼科杂志2010，10，4： | 3 |
| 19 | Correlation between total phenolic and mineral contents with antioxidant activity of eight Malaysian bananas ( Musa sp.)显示文摘 | Shaida Fariza Sulaiman Nor Adlin Md. Yusoff Ibrahim M. Eldeen Eng Meng Seow Azliana Abu Bakar Sajak Supriatno Kheng Leong Ooi | 2010 | Journal of Food Composition and Analysis2010，，1： | 2 |
| 20 | 一个新的杆状病毒凋亡抑制基因的克隆及鉴定显示文摘缺失功能性p35基因的苜蓿尺蠖核形多角体病毒(AcNPV)突变体(vΔP35K/pol+)感染草地夜蛾细胞(Sf9和Sf21)[1]及海灰翅夜蛾细胞(SL2)[2]时,引起细胞凋亡,从而使病毒的感染流产.我们发现海灰翅夜蛾核形多角体病毒(SlNPV)... | 杜全胜 齐义鹏 Nor Chejanovsky | 1998 | 武汉大学学报(自然科学版)1998，44，4： | 2 |
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