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| 1 | Diffusion tensor imaging detects Wallerian degeneration of the corticospinal tract early after cerebral infarction显示文摘To investigate the feasibility and time window of early detection of Wallerian degeneration in the corticospinal tract after middle cerebral artery infarction,23 patients were assessed using magnetic resonance diffusion tensor imaging at 3.0T within 14 days after the infarction.The fractional anisotropy values of the affected corticospinal tract began to decrease at 3 days after onset and decreased in all cases at 7 days.The diffusion coefficient remained unchanged.Experimental findings indicate that diffusion tensor imaging can detect the changes associated with Wallerian degeneration of the corticospinal tract as early as 3 days after cerebral infarction. | Ruiman Xie Min Fang Linjiang Zhou Shanghua Fan Jianying Liu Hongbo Quan Man Luo Dongying Qiu | 2012 | Neural Regeneration Research2012，7，12： | 20 |
| 2 | TRPV1 activation improves exercise endurance and energy metabolism through PGC-1α upregulation in mice显示文摘 | Zhidan Luo Liqun Ma Zhigang Zhao Hongbo He Dachun Yang Xiaoli Feng Shuangtao Ma Xiaoping Chen Tianqi Zhu Tingbing Cao Daoyan Liu Bernd Nilius Yu Huang Zhencheng Yan Zhiming Zhu | 2012 | Cell Research2012，22，3： | 18 |
| 3 | Energy-efficient Bio-inspired Gait Planning and Control for Biped Robot Based on Human Locomotion Analysis显示文摘 | Hongbo Zhu Minzhou Luo Tao Mei Jianghai Zhao Tao Li Fayong Guo | 2016 | Journal of Bionic Engineering2016，13，2： | 8 |
| 4 | Sr-Nd isotope stratification along water depth:An example from Datong hydrological station of Yangtze River显示文摘This study examines the effects of hydrologic sorting and mixing of sources on the Sr-Nd isotopic compositions of suspended sediments at different water depths. The samples were collected from three layers (surface, middle and bottom) at Datong hydrological station of Yangtze River during the flood season of 2010. Our results show that, 87 Sr/ 86 Sr values decrease from surface to bottom, ranging from 0.730332 to 0.720857. ε Nd (0) values range from 14.75 to 10.09, with surface sediments being the most negative. The isotope composition at the middle layer can best represent the mean isotopic composition of the total suspended sediments transported by a river. It is believed that the stratification of Sr-Nd isotope is attributable to mixing of sediments from different sources due to hydrological sorting. Sediments from the upper stream are found to be coarser, and tend to contribute more to the lower water column. Although Sr-Nd isotope is a well acknowledged tool to trace sediment provenance, the current study suggests that the grain size of the samples and the sampling locations should be taken into consideration when applying this method to provenance study. | LUO Chao ZHENG HongBo WU WeiHua WANG Ping CHEN YuLiang WEI XiaoChun | 2012 | Chinese Science Bulletin2012，57，34： | 4 |
| 5 | The metabolic role of LncZBTB39-1:2 in the trophoblast mobility of preeclampsia显示文摘Preeclampsia is characterized by new onset of hypertension and proteinuria after 20 weeks’gestation and is a leading cause of maternal and neonatal morbidity and mortality.The pathogenesis of preeclampsia is often associated with aberrant trophoblast function that leads to shallow placental implantation.However,the exact underlying mechanisms remain unclear.Placental LncZBTB39-1:2 expression level was investigated in 20 healthy placentae and 20 placentae with preeclampsia using qRT-PCR,and the metabolic profile of trophoblasts overexpressing LncZBTB39-1:2 in vitro was analysed using gas chromatography-mass spectrometry(GCeMS).In this study,we found that the expression of LncZBTB39-1:2 was significantly higher in preeclamptic placentae than in healthy placentae.Our metabolomics results have shown that tricarboxylic acid cycle intermediates and metabolites related to carbohydrate metabolism were decreased with the overexpression of LncZBTB39-1:2 in HTR8/SVneo cells.These findings were validated by detecting a lower level of intracellular ATP in HTR8/Vneo cells.Furthermore,the migration of HTR8/SVneo cells was compromised when cells were transfected with a plasmid encompassing LncZBTB39-1:2 overexpression.From these results,we conclude that abnormal levels of LncZBTB39-1:2 expression might lead to aberrant conditions in HTR-8/SVneo trophoblast cells.Aberrant conditions might be associated with dysregulated trophoblast migration and subsequent failure of uterine spiral artery remodelling,a pathogenesis recognised as a contributing factor in the aetiology of preeclampsia. | Yamin Liu Ting-Li Han Xiaofang Luo Yuxiang Bai Xuehai Chen Wei Peng Xi Xiong Philip N.Baker Chao Tong Hongbo Qi | 2018 | Genes & Diseases2018，5，3： | 3 |
| 6 | Single-cell transcriptomic landscape of human blood cells显示文摘High throughput single-cell RNA-seq has been successfully implemented to dissect the cellular and molecular features underlying hematopoiesis.However,an elaborate and comprehensive transcriptome reference of the whole blood system is lacking.Here,we profiled the transcriptomes of 7551 human blood cells representing 32 immunophenotypic cell types,including hematopoietic stem cells,progenitors and mature blood cells derived from 21 healthy donors.With high sequencing depth and coverage,we constructed a single-cell transcriptional atlas of blood cells(ABC) on the basis of both protein-coding genes and long noncoding RNAs(lncRNAs),and showed a high consistence between them.Notably,putative lncRNAs and transcription factors regulating hematopoietic cell differentiation were identified.While common transcription factor regulatory networks were activated in neutrophils and monocytes,lymphoid cells dramatically changed their regulatory networks during differentiation.Furthermore,we showed a subset of nucleated erythrocytes actively expressing immune signals,suggesting the existence of erythroid precursors with immune functions.Finally,a web portal offering transcriptome browsing and blood cell type prediction has been established.Thus,our work provides a transcriptional map of human blood cells at single-cell resolution,thereby offering a comprehensive reference for the exploration of physiological and pathological hematopoiesis. | Xiaowei Xie Mengyao Liu Yawen Zhang Bingrui Wang Caiying Zhu Chenchen Wang Qing Li Yingying Huo Jiaojiao Guo Changlu Xu Linping Hu Aiming Pang Shihui Ma Una Wang Wenbin Cao Shulian Chen Qiuling Li Sudong Zhang Xueying Zhao Wen Zhou Hongbo Luo Guoguang Zheng Erlie Jiang Sizhou Feng Lixiang Chen Lihong Shi Hui Cheng Sha Hao Ping Zhu Tao Cheng | 2021 | National Science Review2021，8，3： | 3 |
| 7 | Comparison of Olanzapine versus Other Second-Generation Antipsychotics in the Improvement of Insight and Medication Discontinuation Rate in Schizophrenia显示文摘 | Hongbo HE Yanling ZHOU Mingzhe YANG Xiongxiong LI Yu-Tao XIANG Jiandong LUO | 2018 | 上海精神医学2018，30，3： | 3 |
| 8 | Eutrophication Evaluation of Water Body at Huailai Section of the Yongding River显示文摘In order to understand the water pollution characteristics in Huailai section of the Yongding River,the monitoring from November of 2016 to October of 2017 was conducted. 6 sampling points were selected for monitoring 6 indicators,and the temporal-spatial variation characteristics of nitrogen and phosphorus in the river were explored. Moreover,the ratio of nitrogen to phosphorus and an exponential universal formula of power function in logarithmic form were used to analyze temporal-spatial variation rules of nitrogen and phosphorus in water,assess the degree of eutrophication,and analyze eutrophication risk. The results showed that water pollution in Huailai section of the Yongding River was more serious. TN was13. 25 times of concentration limit of class III water in the dividing of surface water environment function area in the ' 13 thFive-year' Development Planning' of National Environmental Protection Standard. ON and NO-3-N were the main forms of TN,while mean value of TP was 0. 64 mg/L,and each index had the characteristics of agricultural non-point source pollution. The temporal-spatial distribution characteristics of nitrogen and phosphorus in the water body was obvious. At the time scale,the concentrations of nitrogen and phosphorus in the water body showed seasonal variation; at the space scale,the distribution of nitrogen and phosphorus in the water body was similar. The annual average ratio of nitrogen and phosphorus in Huailai section of the Yongding River was 32. 78,and the phytoplankton was in the overall state of phosphorus limitation. During the flat water period,phosphorus was the limiting nutrient element,and the ratio of nitrogen and phosphorus in the dry period and the abundant water period was suitable for the growth and reproduction of algae. The temporal-spatial variation of water body in Huailai section of the Yongding River was mostly in the ' eutrophication' stage. The maximum EI value was 228. 11 in dry season,and the lowest was 213. 06 in flood season,while it was218. 30 in flat water period. The fluvial dynamics process in Huailai section of the Yongding River was good,and the flow pattern of the river was continuous. The flow velocity of the main stream was 0. 43-1. 45 m/s,which was much larger than that of the algal bloom. The risk of cyanobacteria blooms in the main stream was low. | Zhao Jianguo Li Hongbo Liu Cunqi Li Xiaoyu Chen Xinyong Yan Donghua Luo Ning | 2018 | Meteorological and Environmental Research2018，9，6： | 3 |
| 9 | Observation of the novel “three-pointed star” cage-like (H_2O)_5cluster in a polymeric solid {[Ag_2(bpp)_2(H_2O)_2](chd)·9H_2O}_n显示文摘Coordination polymeric solid, {[Ag 2 (bpp) 2 (H 2 O) 2 ](chd)·9H 2 O} n (1) (bpp = 1,3-bis(4-pyridyl) propane, H 2 chd = 1,4-cyclo-hexanedicarboxylic acid), has been obtained by the solution phase ultrasonic synthesis techniques. The structure established through X-ray structural analysis shows that the compound traps an interesting 1D water tape built by the alternating 'three-pointed star' cage-like pentameric and D 2h tetrameric clusters (C2/c, Z = 4; a = 30.37(2) , b = 9.271(5) , and c = 18.89(1) ; β = 128.47°; V = 4164(4) 3 ). The novelty of the present complex is the rarely crystallographic example of the cage-shaped water pentamer, which is usually ascribed to a less-stable species. A first-principle density functional theory (DFT) calculation demonstrates that the interconnectivity between cage-like pentamers and D 2h tetramers is beneficial for contribution to the structural stabilization of these less-stable water cluster species. | LUO GengGeng XIONG HongBo FU ZhiYong DAI JingCao | 2012 | Science China Chemistry2012，55，10： | 2 |
| 10 | Biomarkers of aging显示文摘Aging biomarkers are a combination of biological parameters to(i)assess age-related changes,(ii)track the physiological aging process,and(iii)predict the transition into a pathological status.Although a broad spectrum of aging biomarkers has been developed,their potential uses and limitations remain poorly characterized.An immediate goal of biomarkers is to help us answer the following three fundamental questions in aging research:How old are we?Why do we get old?And how can we age slower?This review aims to address this need.Here,we summarize our current knowledge of biomarkers developed for cellular,organ,and organismal levels of aging,comprising six pillars:physiological characteristics,medical imaging,histological features,cellular alterations,molecular changes,and secretory factors.To fulfill all these requisites,we propose that aging biomarkers should qualify for being specific,systemic,and clinically relevant. | Aging Biomarker Consortium Hainan Bao Jiani Cao Mengting Chen Min Chen Wei Chen Xiao Chen Yanhao Chen Yu Chen Yutian Chen Zhiyang Chen Jagadish K Chhetri Yingjie Ding Junlin Feng Jun Guo Mengmeng Guo Chuting He Yujuan Jia Haiping Jiang Ying Jing Dingfeng Li Jiaming Li Jingyi Li Qinhao Liang Rui Liang Feng Liu Xiaoqian Liu Zuojun Liu Oscar Junhong Luo Jianwei Lv Jingyi Ma Kehang Mao Jiawei Nie Xinhua Qiao Xinpei Sun Xiaoqiang Tang Jianfang Wang Qiaoran Wang Siyuan Wang Xuan Wang Yaning Wang Yuhan Wang Rimo Wu Kai Xia Fu-Hui Xiao Lingyan Xu Yingying Xu Haoteng Yan Liang Yang Ruici Yang Yuanxin Yang Yilin Ying Le Zhang Weiwei Zhang Wenwan Zhang Xing Zhang Zhuo Zhang Min Zhou Rui Zhou Qingchen Zhu Zhengmao Zhu Feng Cao Zhongwei Cao Piu Chan Chang Chen Guobing Chen Hou-Zao Chen Jun Chen Weimin Ci Bi-Sen Ding Qiurong Ding Feng Gao Jing-Dong JHan Kai Huang Zhenyu Ju Qing-Peng Kong Ji Li Jian Li Xin Li Baohua Liu Feng Liu Lin Liu Qiang Liu Qiang Liu Xingguo Liu Yong Liu Xianghang Luo Shuai Ma Xinran Ma Zhiyong Mao Jing Nie Yaojin Peng Jing Qu Jie Ren Ruibao Ren Moshi Song Zhou Songyang Yi Eve Sun Yu Sun Mei Tian Shusen Wang Si Wang Xia Wang Xiaoning Wang Yan-Jiang Wang Yunfang Wang Catherine CL Wong Andy Peng Xiang Yichuan Xiao Zhengwei Xie Daichao Xu Jing Ye Rui Yue Cuntai Zhang Hongbo Zhang Liang Zhang Weiqi Zhang Yong Zhang Yun-Wu Zhang Zhuohua Zhang Tongbiao Zhao Yuzheng Zhao Dahai Zhu Weiguo Zou Gang Pei Guang-Hui Liu | 2023 | Science China(Life Sciences)2023，66，5： | 2 |
| 11 | Expression of Potential Cancer Stem Cell Marker ABCG2 is Associated with Malignant Behaviors of Hepatocellular Carcinoma显示文摘 | Guang Zhang Zhongxia Wang Weihuan Luo Hongbo Jiao Junhua Wu Chunping Jiang Qiang Xia | 2013 | Gastroenterology Research and Practice2013，，： | 1 |
| 12 | An nhibitory effect of AAAD1 on bladder tumor cellular proliferation in vivo显示文摘 | Hongbo Hu Chunli Luo Xiaozhong Cai | 2006 | Chinese Journal of Clinical Oneology2006，3，： | 1 |
| 13 | SbPS_(4):A novel anode for high-performance sodium-ion batteries显示文摘With the in-depth research of sodium-ion batteries(SIBs),the development of novel sodium-ion anode material has become a top priority.In this work,tube cluster-shaped SbPS_(4)was synthesized by a high-temperature solid phase reaction.Then the typical short tubular ternary thiophosphate SbPS_(4)compounded with graphene oxide(SbPS_(4)/GO)was successfully synthesized after ultrasonication and freeze-drying.SbPS_(4)shows a high theoretical specific capacity(1335 mAh/g)according to the conversion-alloying dual mechanisms.The unique short tube inserted in the spongy graphene structure of SbPS_(4)/GO results in boosting the Na ions transport and alleviating the huge volume change in the charging and discharging processes,improving the sodium storage performance.Consequently,the tubular SbPS_(4)compounded with 10%GO provides an outstanding capacity of 359.58 mAh/g at 500 mA/g.The result indicates that SbPS_(4)/GO anode has a promising application potential for SIBs. | Miao Yang Zhonghui Sun Ping Nie Haiyue Yu Chende Zhao Mengxuan Yu Zhongzhen Luo Hongbo Geng Xinglong Wu | 2022 | Chinese Chemical Letters2022，33，1： | 1 |
| 14 | Superplastic Extrusion of Nano-- structured Si2 Nz O-- Sialon显示文摘 | Luo Junting Zhang Qing Li Hongbo | 2007 | Materials Science Forum2007，，： | 1 |
| 15 | A study of thin liquid films as related to the stability of crude oil emulsions显示文摘 | Fang Hongbo Zhang Lu Luo Lan | 2001 | Journal of Colloid and Interface Science2001，238，： | 1 |
| 16 | Identifying genomic regions controlling ratoon stunting disease resistance in sugarcane(Saccharum spp.) clonal F_(1) population显示文摘The ratoon stunting disease (RSD) of sugarcane,caused by the bacterium Leifsonia xyli subsp.xyli,is one of the major concerns to sugarcane production and breeding programs worldwide.Due to no obvious external symptoms,RSD cannot be easily detected by the growers,hence has reduced the world’s sugarcane production significantly.This study aimed to identify quantitative trait loci (QTL) associated with RSD resistance and to assist in the development of linked molecular markers for marker-assisted breeding to minimize the reduction in sugarcane yield by the RSD infection.A set of 146 individuals derived from a self-crossing of CP80-1827 were evaluated for RSD resistance in a mechanically duplicated inoculated field trial from 2014 to 2017 using tissue blot immunoassay.Leveraging the genetic data and the four years phenotyping data of CP80-1827 selfing population,linkage map construction and QTL analysis were conducted based on clonal F_1 and F_2 mapping population types with GACD V.1.2 and Ici Mapping V.3.3,respectively.A total of 23 QTL associated with RSD resistance were identified,which explained 6%to13%of the phenotypic variation with the two types of software.A total of 82 disease resistance genes were identified by searching these 23 QTL regions on their corresponding regions on the Sorghum bicolor genome (44 genes),sugarcane R570 genome (20 genes),and S.spontaneum genome (18 genes),respectively.Compared with Ici Mapping V.3.3,GACD V.1.2 identified more major (6 vs.3) and stable QTL (2vs.0),and more disease resistance genes (51 vs.31),indicating GACD V.1.2 (clonal F_1 mapping type) is most likely to be more efficient than Ici Mapping (F_2 mapping type) for QTL analysis of a sefling population or clonal F_1 population in clonal species.The identified QTL controlling RSD resistance along with the associated SNP markers will assist sugarcane molecular breeding programs in combating this disease. | Qian You Sushma Sood Ziliang Luo Hongbo Liu Md.Sariful Islam Muqing Zhang Jianping Wang | 2021 | The Crop Journal2021，9，5： | 1 |
| 17 | Thermophysical properties of carbon/carbon composites and physical mechanism of thermal expansion and thermal conductivity显示文摘 | Ruiying Luo Tao Liu Jinsong Li Hongbo Zhang Zhijun Chen Guanglai Tian | 2004 | Carbon2004，，14： | 1 |
| 18 | Experi- mental and theoretical research of a fin-tube type intemally- cooledliquid desiccant dehumidifier显示文摘 | LUO Yimo SHAO Shuangquan XU Hongbo | 2014 | Applied Energy2014，133，15： | 1 |
| 19 | Synthesis,microstructure,and growth mechanism of dendrite ZnO nanowires显示文摘 | Zhang Ye Jia Hongbo Luo Xuhui | 2003 | J Phys Chem B2003，107，33： | 1 |
| 20 | Follow-Up of High-Intensity Focused Ultrasound Treatment for Patients with Hepatocellular Carcinoma显示文摘 | Guoliang Xu Guangyu Luo Longjun He Jianjun Li Hongbo Shan Rong Zhang Yin Li Xiaoyan Gao Shiyong Lin Guobao Wang | 2011 | Ultrasound in Medicine & Biology2011，，12： | 1 |
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