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| 1 | Risk factors for carotid plaque progression after optimising the risk factor treatment: substudy results of the Atherosclerotic Plaque Characteristics Associated with a Progression Rate of the Plaque and a Risk of Stroke in Patients with the carotid Bifurcation Plaque Study (ANTIQUE)显示文摘Background and aim Carotid plaque progression contributes to increasing stroke risk.The study aims to identify factors influencing carotid plaque thickness progression after changing the preventive treatment to the‘treating arteries instead of risk factors’strategy,that is,change in treatment depending on the progression of atherosclerosis.Methods The study participants who completed sonographic controls over the course of 3 years were enrolled to the analysis.Duplex sonography of cervical arteries was performed in 6-month intervals with measurement of carotid plaque thickness.Plaque thickness measurement error(σ)was set as 3 SD.Only evidently stable and progressive plaques(defined as plaque thickness difference between initial and final measurements of˂σand>2σ,respectively)were included to analysis.Univariate and multivariate logistic regression analysis was performed to identify factors influencing plaque progression.Results A total of 1391 patients(466 males,age 67.2±9.2 years)were enrolled in the study.Progressive plaque in at least one carotid artery was detected in 255(18.3%)patients.Older age,male sex,greater plaque thickness,coronary heart disease,vascular surgery/stenting history and smoking were more frequently present in patients with progressive plaque(p˂0.05 in all cases).Multivariate logistic regression analysis identified only the plaque thickness(OR 1.850 for left side,95%CI 1.398 to 2.449;and OR 1.376 for right side,95%CI 1.070 to 1.770)as an independent factor influencing plaque progression.Conclusion Carotid plaque thickness corresponding to stenosis severity is the only independent risk factor for plaque thickness progression after optimising the prevention treatment. | David Školoudik Petra Kešnerova Tomaš Hrbač David Netuka Jaroslav Vomačka Kateřina Langova Roman Herzig Tomaš Belšan | 2022 | Stroke & Vascular Neurology2022，7，2： | 3 |
| 2 | A prospective crossover trial comparing intermittent intravenous and continuous oral iron supplements in peritoneal dialysis patients显示文摘 | Johnson DW Herzig KA Gissane R | 2001 | Nephrol Dial Transplant2001，16，9： | 1 |
| 3 | A prospective crossover trial comparing intermittent intravenous and continuous oral iron supplements in peritoneal dialysis patients 显示文摘 | Johnson DW Herzig KA Gissane R | 2001 | Nephrol Dial Transplant2001，16，9： | 1 |
| 4 | Oral versus intravenous iron supplementation in peritoneal dialysis patients显示文摘 | Johnson DW Herzig KA Gissane R | | 0，，3： | 1 |
| 5 | Oral versus intravenous iron supplementation in peritoneal dialysis patients显示文摘 | Johnson DW Herzig KA Gissane R | 2001 | Petit Dial Int2001，21，3： | 1 |
| 6 | Is C-reactive protein a useful predictor of outcome in peritoneal dialysis patients显示文摘 | Herzig KA Purdie DM Chang W | 2001 | J Am Soe Nephrol2001，12，4： | 1 |
| 7 | Effects of MPEP on expression of food, MDMA or amphetamine conditioned place preference in rats显示文摘 | Herzig V Capuani EM Kovar KA | 2005 | Addict BioI2005，10，： | 1 |
| 8 | A single-centre experience of post-renal transplant lymphoproliferative disorder显示文摘 | Herzig KA Juffs HG Norris D | 2003 | Transpl Int2003，16，7： | 1 |
| 9 | Effects of MPEP on expression of food-,MDMA-or amphetamine-conditioned place preference in rats显示文摘 | Herzig V Capuani EM Kovar KA | 2005 | Addict Biol2005，10，： | 1 |
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