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1Pyogenic liver abscess: Changing patterns in approach显示文摘AIM: To define optimum management of the pyogenic liver abscess and assess new trends in treatment. METHODS: One hundred and sixty nine patients with pyogenic liver abscess managed at Sher-i-Kashmir In- stitute of Medical Sciences, Srinagar, Kashmir (India) from July 2001 to August 2006 were studied to evaluate and define the optimum treatment. RESULTS: Mortality in the surgically treated group of patients was 9.4% (12/119), while those treated non-surgically had a fatality rate of 16.66% (7/42). Multiple liver abscesses treated surgically had a surprisingly low mortality of 30%. The biliary tract (64.97%) was the most common cause of liver abscess. Multiple abscesses, mixed organisms and abscess complications are all associated with a significantly increased mortality. However, the lethality of the primary disease process was the most important factor in determining survival.CONCLUSION: Transperitoneal surgical drainage and antibiotics are the mainstay of treatment. Percutaneous drainage is recommended for high risk patients only.Ajaz A Malik Shams UL Bari Khawaja Abdul Rouf Khurshid Alam Wani 2010World Journal of Gastrointestinal Surgery2010,2,12:15
2分隔状肝脓肿的临床特征分析显示文摘目的分析比较分隔状肝脓肿与无分隔肝脓肿临床特征的差异。方法回顾性分析2011年1月至2021年3月陕西省人民医院和西安交通大学第一附属医院收治的肝脓肿患者的临床资料。共纳入335例肝脓肿患者,其中男性203例,女性132例,年龄(56±14)岁。依据CT和超声结果,将所有患者分为两组:分隔状组(n=68)和非分隔状组(n=267)。记录患者的临床资料,对比临床特征的差异。结果分隔状组患者的中性粒细胞计数9.17(5.97,12.33)×10^(9)/L和总胆红素17.65(11.92,27.84)μmol/L均高于非分隔状组肝脓肿患者的中性粒细胞计数7.81(5.42,10.81)×10^(9)/L和总胆红素12.90(9.00,19.68)μmol/L,差异具有统计学意义(P<0.05)。分隔状组和非分隔状组肝脓肿患者脓肿最大径间差异具有统计学意义(P=0.032)。脓液培养结果显示,分隔状组肝脓肿患者中肺炎克雷伯杆菌阳性者比例高于非分隔状组[41.18%(28/68)比25.84%(69/267),P=0.013]。分隔状组肝脓肿患者氟喹诺酮类抗生素使用比例高于非分隔状组[20.59%(14/68)比10.11%(27/267)],差异具有统计学意义(χ^(2)=5.54,P=0.019)。结论与无分隔单房状肝脓肿相比,分隔状肝脓肿患者的脓肿最大径一般较大,脓液培养肺炎克雷伯杆菌阳性率及氟喹诺酮类抗生素使用比例也较高。杜肇清 池苗苗 林雨昕 武芸冰 耿西林 吴荣谦 2022中华肝胆外科杂志2022,28,4:1
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