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| 1 | Pre-hepatectomy type Ⅳ collagen 7S predicts post-hepatectomy liver failure and recovery显示文摘BACKGROUND Liver resection is an effective treatment for benign and malignant liver tumors.However,a method for preoperative evaluation of hepatic reserve has not yet been established.Previously reported assessments of preoperative hepatic reserve focused only on liver failure in the early postoperative period and did not consider the long-term recovery of hepatic reserve.When determining eligibility for hepatectomy,the underlying pathophysiology needs to be considered to determine if the functional hepatic reserve can withstand both surgery and any postoperative therapy.AIM To identify pre-hepatectomy factors associated with both early postoperative liver failure and long-term postoperative liver function recovery.METHODS This study was a retrospective cohort study.We retrospectively investigated 215 patients who underwent hepatectomy at our hospital between May 2013 and December 2016.Early post-hepatectomy liver failure(PHLF)was defined using the International Study Group of Liver Surgery’s definition of PHLF.Long-term postoperative recovery of liver function was defined as the time taken for serum total bilirubin and albumin levels to return to levels of<2 mg/dL and>2.8 g/dL,respectively,and the time taken for Child-Pugh score to return to Child-Pugh class A.RESULTS Preoperative type IV collagen 7S was identified as a significant independent factor associated with both PHLF and postoperative long-term recovery of liver function.Further analysis revealed that the time taken for the recovery of Child-Pugh scores and serum total bilirubin and albumin levels was significantly shorter in patients with type IV collagen 7S≤6 ng/mL than in those with type IV collagen 7S>6 ng/mL.In additional analyses,similar results were observed in patients without chronic viral hepatitis associated with fibrosis.CONCLUSION Preoperative type IV collagen 7S is a preoperative predictor of PHLF and longterm postoperative liver function recovery.It can also be used in patients without chronic hepatitis virus. | Masatsugu Ishii Osamu Itano Masahiro Shinoda Minoru Kitago Yuta Abe Taizo Hibi Hiroshi Yagi Ayano Takeuchi Hanako Tsujikawa Tokiya Abe Yuko Kitagawa | 2020 | World Journal of Gastroenterology2020，26，7： | 3 |
| 2 | The influence of donor age on liver regeneration and hepatic progenitor cell populations显示文摘 | Yoshihiro Ono Shigeyuki Kawachi Tetsu Hayashida Masatoshi Wakui Minoru Tanabe Osamu Itano Hideaki Obara Masahiro Shinoda Taizo Hibi Go Oshima Noriyuki Tani Kisyo Mihara Yuko Kitagawa | 2011 | Surgery2011，，2： | 2 |
| 3 | Electroacupuneture attenuates both glutamate release and hyperemia after transient ischemia in gerbils显示文摘 | Pang J Itano T Sumitani K | 2003 | Am J Chin Med2003，31，2： | 1 |
| 4 | Identification of hyaluronan-binding domains of aggrecan显示文摘 | Cheung SC Itano N | 1997 | J Biol Chem1997，272，28： | 1 |
| 5 | Language of early and later identified children with hearing loss显示文摘 | Sedey AL Coulter DK | 1998 | Pediatrics1998，102，： | 1 |
| 6 | 1-Methyl-4-phenylpyridinium ion(MPP+) causes DNA fragmentation and increases the Bcl-2 expression in human neuroblastoma, SH-SY5Y cells, through different mechanisms显示文摘 | Itano Y Nomura Y | 1995 | Brain Res1995，704，2： | 1 |
| 7 | Stellate ganglion block modifies the distribution of lymphocyte subsets and,natural-killer cell activity显示文摘 | Yokoyama M Nakatsuka H Itano Y | 2000 | Anesthesiology2000，92，1： | 1 |
| 8 | The superficial precoagula- tion, sealing, and transection method: a 'bloodless' and 'eco- friendly' laparoscopic liver transection technique 显示文摘 | Itano O Ikoma N Takei H | 2015 | Surg Lap- arosc Endosc Percutan Tech2015，25，1： | 1 |
| 9 | The impact of the use of inquiry - based learning as a teaching methodology on the development of critical thinking显示文摘 | Lois Magnussen Dianne Ishida Joanne Itano | 2000 | Journal of Nursing Education2000，39，8： | 1 |
| 10 | Insulin-like growth factor-I(IGF-I) distribution in the tissue and extracellular compartment in different regions of rat brain显示文摘 | Yarnaguchi F Itano T Mizobuchi M | 1990 | Brain Res1990，19，2： | 1 |
| 11 | RNA from Borna disease virus in patients with schizophrenia, schizoaffective pa- tients, and in their biological relatives 显示文摘 | Nunes SO Itano EN Amarante MK | 2008 | J Clin Lab Anal2008，22，4： | 1 |
| 12 | The male sling for post- prostatectomy incontinence: mean followup of 18 months 显示文摘 | Castle EP Andrews PE Itano N | 2005 | J Urol2005，173，5： | 1 |
| 13 | Stellate ganglion block modifies the distribution of lymphocyte subsets and natural - killer cell activity 显示文摘 | Yokoyama M Nakatsuka H Itano Y | 2000 | Anethesiology2000，92，1： | 1 |
| 14 | Treatment options for women with stress urinary incontinence 显示文摘 | Lightner D J Itano NM | 1999 | Mayo Clin Proc1999，74，11： | 1 |
| 15 | Stellate Ganglion Block Modifies the Distribution of Lymphocyte Subsets and Natural-Killer Cell Activity显示文摘 | NAKATSUKA H ITANO Y | 2000 | Anesthesiology(S0003-3022)2000，92，1： | 1 |
| 16 | Temporary indwelling catheter system via the left brachial artery: evaluation in 83 patients with hepatic tumors显示文摘 | Nagaoka S Itano S Nagamatsu H | 2007 | Am J Roentgenol2007，188，： | 1 |
| 17 | Determination of patulin in fruit juice and dried fruit samples by in - tube solid - phase microex- traction coupled with liquid chromatography mass spectrometry 显示文摘 | Kataoka H Itano M Ishizaki A | 2009 | J Chromatogr A2009，1216，18： | 1 |
| 18 | Live vaccine trials against nocardiosis in yellowtail, Seriola quinqueradiata 显示文摘 | Itano T Kawakami H Kono T | 2006 | Aquaculture2006，261，： | 1 |
| 19 | The effects of continuous epidural anesthesia and analgesia on stress response and immune function in patients undergoing radical esophagectomy 显示文摘 | Yokoyama M Itano Y Katayama H | 2005 | Anesth Analg2005，101，5： | 1 |
| 20 | Relationship between hy- aluronan production and metastatic potential of mouse mammary carcinoma cells显示文摘 | ITANO N SAWAI T MIYAISHI O | 1999 | Cancer Res1999，59，： | 1 |
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