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28篇 您的检索式：作者名="Hashad"

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	题名	作者	年代	出处	被引量
1	地塞米松玻璃体腔植入剂治疗中国患者视网膜静脉阻塞继发黄斑水肿的安全性和有效性:随机、假注射对照、多中心研究显示文摘目的评估地塞米松玻璃体腔植入物(DEX)治疗中国患者视网膜静脉阻塞继发黄斑水肿(RVO-ME)的安全性和有效性.方法为期6个月的随机、双盲、假注射对照、多中心、3期临床研究,此后接续为期2个月的开放标签的延展研究.视网膜分支(BRVO)或中央静脉阻塞(CRVO)患眼于基线时接受DEX植入(n=129)或假注射(n=130)治疗;治疗后6个月时,两组中满足再治疗标准的全部患眼均再次接受DEX植入治疗.有效性变量包括最佳矫正视力(BCVA)和黄斑中心凹视网膜厚度(CRT).BCVA检查采用早期治疗糖尿病视网膜病变研究组视力表进行.光相干断层扫描(OCT)检查采用德国Heidelberg公司Spectralis OCT仪或德国Zeiss公司Cirrus OCT仪进行.结果治疗后6个月中(主要终点),DEX治疗组BCVA较基线提高≥15个字母的时间早于假注射组(P<0.001).治疗后第2个月时(效应峰值),DEX治疗组、假注射组BCVA较基线提高≥15个字母患者百分比分别为34.9%,11.5%.DEX治疗组、假注射组平均BCVA较基线分别提高(10.6±10.4)、(1.7±12.3)个字母;平均CRT分别较基线下降(407±212)、(62±224) μm (P<0.001).DEX治疗组CRVO、BRVO患眼治疗效果均优于假注射组.主要常见治疗相关不良事件为眼压升高,均可通过局部降眼压药物控制;无患者需要接受抗青光眼手术.结论 DEX治疗中国患者RVO-ME具有良好的安全性和显著的临床疗效;单次植入DEX较假注射可获得持续3-4个月的视力和解剖结构改善.	黎晓新王宁利梁小玲徐格致 Xiao-yan Li Jenny Jiao Jean Lou Yehia Hashad	2018	中华眼底病杂志2018，34，3：	41
2	Free Circulating Tumor DNA as a Diagnostic Marker for Breast Cancer显示文摘	D. Hashad A. Sorour A. Ghazal I. Talaat	2012	J. Clin. Lab. Anal2012，，：	2
3	Evaluation of HE4 as an extrabiomarker to CA125 to improve detection of ovarian carcinoma: is it time for a step forward显示文摘	Azzam AZ Hashad DI Kamel NA	2013	Arch Gynecol Obstet2013，288，1：	1
4	Evaluation of HE4as an extrabiomarker to CA125to improve detection of ovarian carcinoma:is it time for a step forward显示文摘	Azzam AZ Hashad DI Kamel NA	2013	Arch Gynecol Obstet2013，288，1：	1
5	Evaluation of HE4 as an extra- biomarker to CA125 to improve detection of ovarian carcinoma: is it time for a step forward? 显示文摘	Azzam A Z Hashad D I Karnel N A	2013	Arch Gyneeol Obstet2013，288，1：	1
6	Evaluation of HE4 as an extrabiomarker to CA125 to improve detection of ovarian carcinoma:is it time for a step forward? 显示文摘	Azzam AZ Hashad DI Kamel NA	2013	Arch Gynecol Obstet2013，288，：	1
7	Evaluation of HE4 as an extrabiomarker to CA125 to improve detection of ovar- ian carcinoma:is it time for a step forward 显示文摘	Azzam AZ Hashad DI Kamel NA	2013	Arch Gy- necol Obstet2013，288，1：	1
8	C242T polymorphism of NADPH oxidase p22phox gene reduces the risk of coronary artery disease in a random sample of Egyptian population显示文摘	HASHAD I M ABDEL RAHMAN M F ABDELMAKSOUD S M	2014	Mol Biol Rep2014，41，4：	1
9	Safety of no bowel preparation before ileal urinary diversion显示文摘	Hashad MM Atta M Elabbady A		0，，：	1
10	Evaluation of HE4 as an ex trabiomarker to CA125 to improve detection of ovarian carcino ma:is it time for a step forward显示文摘	Azzam AZ Hashad DI Kamel NA	2013	Arch Gynecol Obstet2013，288，16：	1
11	Use of free fetal DNA in prenatal noninvasive detection of fetal RhD status and fetal gender by molecular analysis of maternal plasma 显示文摘	Sedrak M Hashad D Adel H	2011	GenetTest Mol Biomarkers2011，15，9：	1
12	C242T polymorphism of NADPH oxidase p22phox gene reduces the risk of coronary artery disease in a random sample of Egyptian population显示文摘	Ingy M. Hashad Mohamed F. Abdel Rahman Sahar M. Abdel-Maksoud Khalda S. Amr Laila K. Effat Gamal M. Shaban Mohamed Z. Gad	2014	Molecular Biology Reports2014，，：	1
13	Free circulating tumor DNA as a diagnostic marker for breast cancer 显示文摘	Hashad D Sorour A Ghazal A	2012	J Clin Lab Anal2012，26，6：	1
14	Endothelial nitric oxide synthase (G894T) gene polymorphism in a random sample of the Egyptian population:comparison with myocardial infarction patients显示文摘	Gad MZ Abdel Rahman MF Hashad IM	2012	Genet Test Mol Biomarkers2012，16，7：	1
15	C242T polymorphism of NADPH oxidase p22phox gene reduces the risk of coronary artery disease in a random sample of Egyptian population显示文摘	Hashad IM Abdel Rahman MF Abdel-Maksoud SM	2014	/Viol Biol Rep2014，41，4：	1
16	Safety of no bowel preparation before ileal urinary diversion显示文摘	HASHAD MM ATTA M ELABBADY A	2012	BJU Int2012，110，11：	1
17	Bovine natural resistance associated macrophage protein 1 (Nramp 1) gene 显示文摘	Feng J Li Y Hashad M	1996	Genome Res1996，6，：	1
18	C242T polymorphism of NADPH oxidase p22phox gene reduces the risk of coronary artery disease in a random sample of Egyptian population 显示文摘	Hashad IM Abdel Rahman MF AbdeI-Maksoud SM	2014	Mol Biol Rep2014，41，4：	1
19	Garnet-bearing leucogranite in the Ei-Hudi area, southern EgylSt: Evidence of crustal anatexis during Pan-African low pressure reginal metamorphism 显示文摘	Moghazi A M Hassanen M A Hashad M H	2001	Journal of African Earth Science2001，33，2：	1
20	Bovine natural resistance associated macrophage proteinl(Nrampl) gene显示文摘	Feng J Li Y Hashad M	1996	Genome Res1996，，6：	1

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