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| 1 | 世界卫生组织(WHO)造血与淋巴组织肿瘤分类方案:临床顾问委员会会议报告显示文摘引言 :从 1995年开始 ,欧洲病理学工作者协会和血液病理学会一直致力于制定一个新的世界卫生组织 (WHO)血液恶性肿瘤分类方案 ,该分类方案包括淋巴系肿瘤、髓系肿瘤、组织细胞肿瘤和肥大细胞肿瘤。 材料与方法 :此项 WHO计划共组成十个病理学工作者委员会 ,负责确定病种和作出定义。另外还成立一个由国际血液学家和肿瘤学家组成的临床顾问委员会 (CAC)以保证该分类的临床实用性。 1997年 11月召开会议讨论了与该分类有关的临床问题。 结果 :WHO采纳了 1994年国际淋巴瘤研究组 (IL SG)报告的修订欧美淋巴系肿瘤分类 (REAL)方案作为淋巴系肿瘤的分类方案。该方案的分类方法遵循以下原则 :分类应是联合应用形态学、免疫表型、遗传特征及临床特征能够清楚界定的“真实存在”(“real”)病种的名录 ,上述各项特征的相对重要性因病种不同而异 ,不存在任何“金标准”。 WHO将 REAL分类原则延用于髓系肿瘤和组织细胞肿瘤 ,髓系肿瘤的分类包括联合应用细胞形态学和细胞遗传学异常能够界定的各个病种。围绕一系列临床问题召集的这次 CAC会议 ,就提交的大多数问题达成共识 ,这些问题及共识将详述于下。对于另外一些问题 ,CAC认为淋巴系肿瘤临床分组既无必要也不必需 ,患者的治疗取决于淋巴瘤的具体类型 ,如有? | N L Harris E S Jaffe J Diebold G Flandrin H K Muller-Hermelink J Vardiman T A Lister C D Bloomfield 张凤奎 郝玉书 | 2001 | 白血病.淋巴瘤2001，10，3： | 20 |
| 2 | Highly efficient GaAs solar cells by limiting light emission angle显示文摘In a conventional flat plate solar cell under direct sunlight,light is received from the solar disk,but is re-emitted isotropically.This isotropic emission corresponds to a significant entropy increase in the solar cell,with a corresponding drop in efficiency.Here,using a detailed balance model,we show that limiting the emission angle of a high-quality GaAs solar cell is a feasible route to achieving power conversion efficiencies above 38%with a single junction.The highest efficiencies are predicted for a thin,light trapping cell with an ideal back reflector,though the scheme is robust to a non-ideal back reflector.Comparison with a conventional planar cell geometry illustrates that limiting emission angle in a light trapping geometry not only allows for much thinner cells,but also for significantly higher overall efficiencies with an excellent rear reflector.Finally,we present ray-tracing and detailed balance analysis of two angular coupler designs,show that significant efficiency improvements are possible with these couplers,and demonstrate initial fabrication of one coupler design. | Emily D Kosten Jackson H Atwater James Parsons Albert Polman Harry A Atwater | 2013 | Light(Science & Applications)2013，2，1： | 9 |
| 3 | New therapeutic opportunities for Hepatitis C based on small RNA显示文摘Hepatitis C virus (HCV) infection is one of the major causes of chronic liver disease, including cirrhosis and liver cancer and is therefore, the most common indication for liver transplantation. Conventional antiviral drugs such as pegylated interferon-alpha, taken in combination with ribavirin, represent a milestone in the therapy of this disease. However, due to different viral and host factors, clinical success can be achieved only in approximately half of patients, making urgent the requirement of exploiting alternative approaches for HCV therapy. Fortunately, recent advances in the understanding of HCV viral replication and host cell interactions have opened new possibilities for therapeutic intervention. The most recent technologies, such as small interference RNA mediated gene-silencing, anti-sense oligonucleotides (ASO), or viral vector based gene delivery systems, have paved the way to develop novel therapeutic modalities for HCV. In this review, we outline the application of these technologies in the context of HCV therapy. In particular, we will focus on the newly defined role of cellular microRNA (miR-122) in viral replication and discuss its potential for HCV molecular therapy. | Qiu-wei Pan Scot D Henry Bob J Scholte Hugo W Tilanus Harry LA Janssen Luc JW van der Laan | 2007 | World Journal of Gastroenterology2007，13，33： | 4 |
| 4 | 大丽轮枝菌Nit突变体产生及其营养亲和性测定显示文摘从DNA限制性酶切多态性(RFLPs)的A组和B组中选用了具代表性的7个大丽轮枝菌菌系作营养亲和性测定。病菌分别接种在含氯酸钾15~25g/l的基本培养基(MM)、梅干培养基(PLA)、玉米粉琼脂培养基(CMA)和马铃薯葡萄糖培养基(PDA)上,从中获得了41个不能还原利用硝酸钠作为唯一氮源正常生长的突变体(Nit)。Nit突变体以PDA和PLA含氯酸钾20~25g/l的两种培养基上发生频率较高。根据对不同氮源利用生长情况,获得了Nit突变体5种生理表现型。以Nit 1居多(50%~100%),其次为Nit M(0~50%)。表现型互补的Nit 1与Nit M突变体营养亲和性测定结果表明,测试菌系可划分为VCG01和VCG02两个营养亲和群,分别含RFLPs A组的4个菌系和B组的3个菌系。 | 杨家荣 Harris D C | 1992 | 西北农业学报1992，1，1： | 4 |
| 5 | Free radicals and grape seed proanthocyanidin extract: importance in human health and disease prevention显示文摘 | Debasis Bagchi Manashi Bagchi Sidney J Stohs Dipak K Das Sidhartha D Ray Charles A Kuszynski Shantaram S Joshi Harry G Pruess | 2000 | Toxicology2000，，2： | 3 |
| 6 | Change in ecosystem service values in the San Antonio area, Texas显示文摘 | Urs P Kreuter Heather G Harris Marty D Matlock Ronald E Lacey | 2001 | Ecological Economics2001，，3： | 3 |
| 7 | Association of Helicobacter pylori infection with gastric carcinoma: a meta-analysis显示文摘 | Guy D Eslick Lynette L.-Y Lim Julie E Byles Harry H-X Xia Nicholas J Talley | 1999 | The American Journal of Gastroenterology1999，，： | 2 |
| 8 | Processing of low-density silica gel by critical point drying or ambient pressure drying显示文摘 | Valerie D Land Thomas M Harris Dale C Teeters | 2001 | Journal of Non-Crystalline Solids2001，，1： | 2 |
| 9 | Quantitative X-ray diffraction analysis and its application to various coals显示文摘 | L Lu V Sahajwalla C Kong D Harris | 2001 | Carbon2001，，12： | 2 |
| 10 | Change in ecosystem service values in the San Antonio area, Texas显示文摘 | Urs P Kreuter Heather G Harris Marty D Matlock Ronald E Lacey | 2001 | Ecological Economics2001，，3： | 2 |
| 11 | Molecular mechanisms of cardioprotection by a novel grape seed proanthocyanidin extract显示文摘 | Debasis Bagchi Chandan K Sen Sidhartha D Ray Dipak K Das Manashi Bagchi Harry G Preuss Joe A Vinson | 2003 | Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis2003，，： | 2 |
| 12 | Adaptive radiation in the afrotropical region of the paleotropical genus Lissocephala (drosophilidae) on the pantropical genus Ficus (Moraceae) 显示文摘 | HARRY M SOLIGNAC M LACHAISE D | 1996 | Journal of Biogeography1996，23，4： | 1 |
| 13 | Effects of nicotine on cognitive deficits in schizophrenia显示文摘 | Harris JG Kongs S Allensworth D | 2004 | Neuropsychopharmacology2004，29，： | 1 |
| 14 | Empowerment, Marginalization, and 'Community-integrated' GIS 显示文摘 | Harris T Weiner D | 1998 | Cartography and Geographic Information Systems1998，25，2： | 1 |
| 15 | Mechanism of mechanical failure of sapphire at high temperature 显示文摘 | Harris D C Sehmid Frederick Mecholsky J J | 1994 | Proc SPIE1994，2286，： | 1 |
| 16 | Computational fluid dynamics for chemical reactor engineering显示文摘 | Harris C K Roekaerts D Rosendal F J J | 1996 | Chem Eng Sci1996，51，10： | 1 |
| 17 | Complete genomes of two clinical Staphylococcus aureus strains:evidence for the rapid evolution of virulence and drug resistance显示文摘 | Holden MT Feil EJ Lindsay JA Peacock SJ Day NP Enright MC Foster TJ Moore CE Hurst L Atkin R Barron A Bason N Bentley SD Chillingworth C Chillingworth T Churcher C Clark L Corton C Cronin A Doggett J Dowd L Feltwell T Hance Z Harris B Hauser H Holroyd S Jagels K James KD Lennard N Line A Mayes R Moule S Mungall K Ormond D Quail MA Rabbinowitsch E Rutherford K Sanders M Sharp S Simmonds M Stevens K Whitehead S Barrell BG Spratt BG Parkhill J | 2004 | Proc Natl Acad Sci USA2004，101，26： | 1 |
| 18 | The role of oxidative stress in noise-induced hearing loss显示文摘 | Henderson D Bielefeld EC Harris KC | 2006 | Ear Hear2006，27，1： | 1 |
| 19 | The efficacy of spinosad against the western flower thrips,Frankliniella occidentalis,and its impact on associated biological control agents on greenhouse cucumbers in southern Ontario显示文摘 | Jones T Scott D C Harris R | 2005 | Pest Manag Sci2005，61，： | 1 |
| 20 | Odour intensities of hop oil components 显示文摘 | Guadagni D G Buttery R G Harris J | 1966 | Journal of the Science of Food and Agriculture1966，17，3： | 1 |
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