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19篇 您的检索式:作者名="Haofan"
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1Carbon Capture and Storage:History and the Road Ahead显示文摘The large-scale deployment of carbon capture and storage(CCS)is becoming increasingly urgent in the global path toward net zero emissions;however,global CCS deployment is significantly lagging behind its expected contribution to greenhouse gas emission reduction.Reviewing and learning from the examples and history of successful CCS practices in advanced countries will help other countries,including China,to promote and deploy CCS projects using scientific methods.This paper shows that the establishment of major science and technology CCS infrastructures in advanced countries has become the main source of CCS technological innovation,cost reduction,risk reduction,commercial promotion,and talent training in the development and demonstration of key CCS technologies.Sound development of CCS requires a transition from pilot-scale science and technology infrastructures to large-scale commercial infrastructures,in addition to incentive policies;otherwise,it will be difficult to overcome the technical barriers between small-scale demonstrations and the implementation of million-tonne-scale CCS and ten-million-tonne-scale CCS hubs.Geological CO_(2) storage is the ultimate goal of CCS projects and the driving force of CO_(2) capture.Further improving the accuracy of technologies for the measurement,monitoring,and verification(MMV)of CO_(2) storage capacity,emission reduction,and safety remains a problem for geological storage.CO_(2) storage in saline aquifers can better couple multiple carbon emission sources and is currently a priority direction for development.Reducing the energy consumption of lowconcentration CO_(2) capture and the depletion of chemical absorbents and improving the operational efficiency and stability of post-combustion CO_(2) capture systems have become the key constraints to largescale CCS deployment.Enhanced oil recovery(EOR)is also important in order for countries to maximize fossil fuel extraction instead of importing oil from less environmentally friendly oil-producing countries.Jinfeng Ma Lin Li Haofan Wang Yi Du Junjie Ma Xiaoli Zhang Zhenliang Wang 2022Engineering2022,8,7:9
2Synthesis of carboxymethyl chitosan and determination of substitution degree显示文摘Chen Haofan Pan Shirong Wang Qinmei 2003J Huazhong Univ Sci Tech: Health Sci2003,32,2:1
3Prediction of effective percutaneous transhepatic biliary drainage in patients with hepatocellular carcinoma: A multi-central retrospective study显示文摘Background and aim:Percutaneous transhepatic biliary drainage(PTBD)does not always lead to a reduction in serum total bilirubin(TBil)level in patients with hepatocellular carcinoma and obstructive jaundice.We aimed to develop a model for pre-PTBD prediction of post-procedural TBil decrease in these patients.Materials and methods:Retrospective database searches were conducted at four teaching hospitals(reference period:January 2010 to December 2018),and baseline characteristics of eligible patients were extracted.Any decrease in TBil after PTBD and the lowest level of TBil post-PTBD<5 mg/dL,3 mg/dL,and 2 mg/dL were each taken as the standard of effectiveness for computation of its own predictive nomogram.For data dimension decrease and feature selection,the least absolute shrinkage and selection operator(LASSO)regression model was used.A multivariable logistic regression analysis was used to develop nomograms.Each nomogram's performance was internally evaluated for its calibration,discriminative ability,and clinical usefulness.Results:Included in the study were 138 patients.The model for end-stage liver disease(MELD)score,platelet count,and portal vein thrombosis(PVT)were predictors in the nomogram for any decrease in TBil;international normalized ratio(INR),MELD score,platelet count,and PVT were predictors for a decrease to<5 mg/dL;MELD score,cholinesterase level(CHE),platelet count,and PVT were predictors for a decrease to<3 mg/dL;and MELD score,CHE,platelet count,and pre-albumin level were predictors for a decrease to<2 mg/dL.The clinical value of the nomograms was proven by decision curve analysis.Conclusions:These models may help inform clinical decision making for performing PTBD procedures.Haofan Wang Yitao Mao Chunning Zhang Xiaojun Hu Bin Chen Luwen Mu Shuyi Wang Yifen Lin Zhanwang Xiang Mingsheng Huang 2022Liver Research2022,6,4:1
4Towards 6G: Paradigm of Realistic Terahertz Channel Modeling显示文摘Terahertz(THz)communications are envisioned as a key technology for the sixth-generation wireless communication system(6G).However,it is not practical to perform large-scale channel measurements with high degrees of freedom at THz frequency band.This makes empirical or stochastic modeling approaches relying on measurements no longer stand.In order to break through the bottleneck of scarce fulldimensional channel sounding measurements,this paper presents a novel paradigm for THz channel modeling towards 6G.With the core of high-performance ray tracing(RT),the presented paradigm requires merely quite limited channel sounding to calibrate the geometry and material electromagnetic(EM)properties of the three-dimensional(3D)environment model in the target scenarios.Then,through extensive RT simulations,the parameters extracted from RT simulations can be fed into either ray-based novel stochastic channel models or cluster-based standard channel model families.Verified by RT simulations,these models can generate realistic channels that are valuable for the design and evaluation of THz systems.Representing two ends of 6G THz use cases from microscopy to macroscopy,case studies are made for close-proximity communications,wireless connections on a desktop,and smart rail mobility,respectively.Last but not least,new concerns on channel modeling resulting from distinguishing features of THz wave are discussed regarding propagation,antenna array,and device aspects,respectively.Ke Guan Haofan Yi Danping He Bo Ai Zhangdui Zhong 2021China Communications2021,18,5:1
5Combination of radiofrequency ablation and sequential cellular immunotherapy improves progression‐free survival for patients with hepatocellular carcinoma显示文摘Jiuwei Cui Nanya Wang Hengjun Zhao Haofan Jin Guanjun Wang Chao Niu Hiroshi Terunuma Hua He Wei Li 2014Int. J. Cancer2014,,:1
6Strategies for improving adipose-derived stem cells for tissue regeneration显示文摘Adipose-derived stem cells(ADSCs)have promising applications in tissue regeneration.Currently,there are only a few ADSC products that have been approved for clinical use.The clinical application of ADSCs still faces many challenges.Here,we review emerging strategies to improve the therapeutic efficacy of ADSCs in tissue regeneration.First,a great quantity of cells is often needed for the stem cell therapies,which requires the advanced cell expansion technologies.In addition cell-derived products are also required for the development of‘cell-free’therapies to overcome the drawbacks of cell-based therapies.Second,it is necessary to strengthen the regenerative functions of ADSCs,including viability,differentiation and paracrine ability,for the tissue repair and regeneration required for different physiological and pathophysiological conditions.Third,poor delivery efficiency also restricts the therapeutic effect of ADSCs.Effective methods to improve cell delivery include alleviating harsh microenvironments,enhancing targeting ability and prolonging cell retention.Moreover,we also point out some critical issues about the sources,effectiveness and safety of ADSCs.With these advanced strategies to improve the therapeutic efficacy of ADSCs,ADSC-based treatment holds great promise for clinical applications in tissue regeneration.Xin Yuan Li Li Haofan Liu Jing Luo Yongchao Zhao Cheng Pan Xue Zhang Yuwen Chen Maling Gou 2022Burns & Trauma2022,10,1:1
7Gold nanop- article-decorated MoS2 nanosheets for simultaneous de- tection of ascorbic acid, dopamine and uric acid显示文摘SUN Haofan CHAO Jie SU Shao 2014RSC Advances2014,4,27:1
8Highly sensi- tive and selective determination of dopamine in the pres- ence of ascorbic acid using gold nanoparticles-decorated MoS2 nanosheets modified electrode 显示文摘SU Shao SUN Haofan XU Fei 2013Electroanaly- sis2013,25,11:1
9Platinum nanoparticles supported MoS2 nanosheet for simultaneous detection of dopamine and uric acid显示文摘Herein, platinum nanoparticles-decorated molybdenum disulfide(Pt NPs@MoS_2) nanocomposite has been synthesized via a microwave-assisted hydrothermal method, which was characterized by transmission electron microscopy(TEM) and powder X-ray diffraction(XRD). This MoS_2-based nanocomposite modified glass carbon electrode(Pt NPs@MoS_2/GCE) exhibited excellent electrocatalytic activity toward dopamine(DA) and uric acid(UA) due to their synergistic effect. Two well-defined oxidation peaks of DA and UA were obtained at Pt NPs@MoS_2/GCE with a large peak separation of 160 m V(DA-UA), suggesting that the modified electrode could individually or simultaneously analyze DA and AA. Under the optimal conditions, the peak currents of DA and UA were linearly dependent on their concentrations in the range of 0.5–150 and 5–1000 mmol/L with detection limit of 0.17 and 0.98 mmol/L, respectively. The proposed MoS_2-based sensor can also be employed to examine DA and UA in real samples with satisfactory results. Therefore, the Pt NPs@MoS_2 nanocomposite might offer a good possibility for electrochemical sensing and other electrocatalytic applications.Jie Chao Xiaoyan Han Haofan Sun Shao Su Lixing Weng Lianhui Wang 2016Science China Chemistry2016,59,3:1
10Use of Deep Learning for Continuous Prediction of Mortality for All Admissions in Intensive Care Units显示文摘The mortality rate in the intensive care unit(ICU)is a key metric of hospital clinical quality.To enhance hospital performance,many methods have been proposed for the stratification of patients’different risk categories,such as severity scoring systems and machine learning models.However,these methods make capturing time sequence information difficult,posing challenges to the continuous assessment of a patient’s severity during their hospital stay.Therefore,we built a predictive model that can make predictions throughout the patient’s stay and obtain the patient’s risk of death in real time.Our proposed model performed much better than other machine learning methods,including logistic regression,random forest,and XGBoost,in a full set of performance evaluation processes.Thus,the proposed model can support physicians’decisions by allowing them to pay more attention to high-risk patients and anticipate potential complications to reduce ICU mortality.Guangjian Zeng Jinhu Zhuang Haofan Huang Mu Tian Yi Gao Yong Liu Xiaxia Yu 2023Tsinghua Science and Technology2023,28,4:0
11Detector development at the Back-n white neutron source显示文摘Purpose Back-n is a white neutron beamline at China spallation neutron source,which was established in the year of 2018.It is a powerful facility for nuclear data measurement,neutron detector calibration,and radiation effect research.Method A series of detectors were built for different experiments,including beam monitoring,beam profile measurement,neutron induced secondaries(fission fragments,light charged particles and gamma)cross section measurement,and neutron resonance radiography,etc.A common digitization electronics and a cluster-based DAQ were developed for these detector systems.Most detectors have been employed at Back-n and serviced for experiments from the beginning of the beamline running.Results and conclusion As an overview of detectors of Back-n,the details of the detector design and the experiment performing are described in this paper.Some developing systems,e.g.,MTPC and B-MCP,are also included.Fan Ruirui Li Qiang Bao Jie Li Yang Liu Rong Jiang Wei Ren Jie Zhang Qiwei Cao Ping Gu Minhao Ren Zhizhou Yi Han Tang Jingyu An Qi Bai Haofan Bai Jiangbo Chen Qiping Chen Yonghao Chen Zhen Cui Zengqi Fan Anchuan Feng Changqing Feng Fanzhen Gao Keqing Han Changcai Han Zijie He Guozhu He Yongcheng Hong Yang Hu Yiwei Huang Hanxiong Jia Weihua Jiang Haoyu Jiang Zhijie Jin Zhengyao Kang Ling Li Bo Li Chao Li Gong Li Jiawen Li Xiao Liu Jie Liu Shubin Luan Guangyuan Ning Changjun Qi Binbin Ruan Xichao Song Zhaohui Sun Kang Tan Zhixin Tang Shengda Wang Pengcheng Wang Zhaohui Wen Zhongwei Wu Xiaoguang Wu Xuan Xie Likun Yang Yiwei Yu Yongji Zhang Guohui Zhang Linhao Zhang Mohan Zhang Xianpeng Zhang Yuliang Zhang Yue Zhang Zhiyong Zhao Maoyuan Zhou Luping Zhou Zhihao Zhu Kejun The CSNS Back-n Collaboration 2023Radiation Detection Technology and Methods2023,7,2:0
12Alluvial Fan Facies and Their Distribution in the Lower Talang Acar Formation, Northeast Betara Oilfield, Indonesia显示文摘This paper studies the alluvial fan facies characteristics and distribution in the Lower Talang Acar Formation in the Northeast Betara Oilfield. The conglomerate sedimentary characteristics and its distribution were studied based on core data, logging interpretation and seismic property analysis. The research indicated that alluvial fan deposits of Bed F in the Lower Talang Akar Formation were characterized by coarse granularity, poor sorting and low quality. Sand-bodies accumulate longitudinally, and inter-layers are poorly developed, extending locally in the transverse orientation. Typical logging response of alluvial fan system is summarized, and conglomerate is characterized by low gamma-ray (GR) intensity, low resistance, high density and low value between DLD and LLD, which reflects poor physical reservoir properties, coarse rocks and relatively high density. Conglomerate is developed mainly in the northeast and middle-south of the studied area. The upper part of bed F is found in a small area in the middle-south, while the lower part of bed F is developed in a relatively large area in the middle-south.Xie Chuanli Ma Haofan Liang Honggang Li Dongmei Qi Xiuli Xian Benzhong 2007Petroleum Science2007,4,2:0
13Nerve transfer with 3D-printed branch nerve conduits显示文摘Background:Nerve transfer is an important clinical surgical procedure for nerve repair by the coaptation of a healthy donor nerve to an injured nerve.Usually,nerve transfer is performed in an end-to-end manner,which will lead to functional loss of the donor nerve.In this study,we aimed to evaluate the efficacy of 3D-printed branch nerve conduits in nerve transfer.Methods:Customized branch conduits were constructed using gelatine-methacryloyl by 3D print-ing.The nerve conduits were characterized both in vitro and in vivo.The efficacy of 3D-printed branch nerve conduits in nerve transfer was evaluated in rats through electrophysiology testing and histological evaluation.Results:The results obtained showed that a single nerve stump could form a complex nerve network in the 3D-printed multibranch conduit.A two-branch conduit was 3D printed for transferring the tibial nerve to the peroneal nerve in rats.In this process,the two branches were connected to the distal tibial nerve and peroneal nerve.It was found that the two nerves were successfully repaired with functional recovery.Conclusions:It is implied that the two-branch conduit could not only repair the peroneal nerve but also preserve partial function of the donor tibial nerve.This work demonstrated that 3D-printed branch nerve conduits provide a potential method for nerve transfer.Jing Zhang Jie Tao Hao Cheng Haofan Liu Wenbi Wu Yinchu Dong Xuesong Liu Maling Gou Siming Yang Jianguo Xu 2022Burns & Trauma2022,10,1:0
14Nanosecond laser shock detonation of nanodiamonds:from laser-matter interaction to graphite-to-diamond phase transition显示文摘Nanodiamonds(NDs)have been widely explored for applications in drug delivery,optical bioimaging,sensors,quantum computing,and others.Room-temperature nanomanufacturing of NDs in open air using confined laser shock detonation(CLSD)emerges as a novel manufacturing strategy for ND fabrication.However,the fundamental process mechanism remains unclear.This work investigates the underlying mechanisms responsible for nanomanufacturing of NDs during CLSD with a focus on the laser-matter interaction,the role of the confining effect,and the graphite-to-diamond transition.Specifically,a first-principles model is integrated with a molecular dynamics simulation to describe the laser-induced thermo-hydrodynamic phenomena and the graphite-to-diamond phase transition during CLSD.The simulation results elucidate the confining effect in determining the material’s responses to laser irradiation in terms of the temporal and spatial evolutions of temperature,pressure,electron number density,and particle velocity.The integrated model demonstrates the capability of predicting the laser energy threshold for ND synthesis and the efficiency of ND nucleation under varying processing parameters.This research will provide significant insights into CLSD and advance this nanomanufacturing strategy for the fabrication of NDs and other high-temperature-high-pressure synthesized nanomaterials towards extensive applications.Xing Zhang Haofan Sun Bo Mao Rui Dai Houlong Zhuang Yiliang Liao Qiong Nian 2022International Journal of Extreme Manufacturing2022,4,1:0
153D printing of functional nerve guide conduits显示文摘Nerve guide conduits(NGCs),as alternatives to nerve autografts and allografts,have been widely explored as an advanced tool for the treatment of peripheral nerve injury.However,the repairing efficiency of NGCs still needs significant improvements.Functional NGCs that provide a more favorable microenvironment for promoting axonal elongation and myelination are of great importance.In recent years,3D printing technologies have been widely applied in the fabrication of customized and complex constructs,exhibiting great potential for tissue engineering applications,especially for the construction of functional NGCs.In this review,we introduce the 3D printing technologies for manufacturing functional NGCs,including inkjet printing,extrusion printing,stereolithographybased printing and indirect printing.Further,we summarize the current methods and strategies for constructing functional NGCs,such as designing special conduit architectures,using appropriate materials and co-printing with different biological cues.Finally,the challenges and prospects for construction of functional NGCs are also presented.Yulan Huang Wenbi Wu Haofan Liu Yuwen Chen Bo Li Zhiyuan Gou Xun Li Maling Gou 2021Burns & Trauma2021,9,1:0
16Investigation and analysis of vascular plant resources and diversity in Wuyi Mountain,Fujian Province显示文摘Wuyi Mountain,located in the north of Fujian Province,China,is renowned for its abundant medicinal plant resources.In July 2014,the 8th(second team)of Shenyang Pharmaceutical University’s Chinese Medicine Resources Scientific Expedition Team conducted field investigation in the area.Through specimen collection and extensive literature review,the team identified and analyzed 223 vascular plant species from 175 genera and 85 families.The most dominant families were Compositae and Rosaceae,and perennial herbs were the predominant species,accounting for 44.39%of the total species identified.Notably,we documented five precious and rare medicinal plants unique to Wuyi Mountain.This study updates the database of plant resources and diversity in the region,providing a valuable reference for future studies.Finally,we put forward some suggestions to enhance the conservation and sustainable utilization of Wuyi Mountain’s plant resources.Peiying Chen Ruru Xiong Jun Yuan Minglong Huang Zhuo Tao Bowen Zhang Fanglin Luo Lisha Liu Qian Wang You Zhou Haofan Zhang Zijie Wei Jie Yang Jiangang Chen Kui Wu Anhua Wang Jingming Jia 2024Asian Journal of Traditional Medicines2024,19,1:0
17Serine Plays an Important Role in Maintaining the Survival of Tumor Cells显示文摘Serine metabolism is becoming more and more important in a variety of cancers.This paper reviews the discovery of serine synthesis pathway and its imbalance in cancer,and the recent research results on serine metabolism in cancer,and also discuss on how serine metabolism plays a role in cancer.Quan Luo Jingwen Tan Haofan Xi Ju Wang Liping Wang 2021Proceedings of Anticancer Research2021,5,2:0
18Open-source algorithm and software for computed tomography-based virtual pancreatoscopy and other applications显示文摘Pancreatoscopy plays a significant role in the diagnosis and treatment of pancreatic diseases.However,the risk of pancreatoscopy is remarkably greater than that of other endoscopic procedures,such as gastroscopy and bronchoscopy,owing to its severe invasiveness.In comparison,virtual pancreatoscopy(VP)has shown notable advantages.However,because of the low resolution of current computed tomography(CT)technology and the small diameter of the pancreatic duct,VP has limited clinical use.In this study,an optimal path algorithm and super-resolution technique are investigated for the development of an open-source software platform for VP based on 3D Slicer.The proposed segmentation of the pancreatic duct from the abdominal CT images reached an average Dice coefficient of 0.85 with a standard deviation of 0.04.Owing to the excellent segmentation performance,a fly-through visualization of both the inside and outside of the duct was successfully reconstructed,thereby demonstrating the feasibility of VP.In addition,a quantitative analysis of the wall thickness and topology of the duct provides more insight into pancreatic diseases than a fly-through visualization.The entire VP system developed in this study is available at http://gffzz188fe103f8f1460aso0vkf6vwp6uf6xcx.ffgz.tsg.suse.edu.cn/gaoyi/VirtualEndoscopy.git.Haofan Huang Xiaxia Yu Mu Tian Weizhen He Shawn Xiang Li Zhengrong Liang Yi Gao 2022Visual Computing for Industry,Biomedicine,and Art2022,5,1:0
19Lithium-Ion Charged Polymer Channels Flattening Lithium Metal Anode显示文摘The concentration difference in the near-surface region of lithium metal is the main cause of lithium dendrite growth.Resolving this issue will be key to achieving high-performance lithium metal batteries(LMBs).Herein,we construct a lithium nitrate(LiNO_(3))-implanted electroactiveβphase polyvinylidene fluoride-co-hexafluoropropylene(PVDF-HFP)crystalline polymorph layer(PHL).The electronegatively charged polymer chains attain lithium ions on the surface to form lithium-ion charged channels.These channels act as reservoirs to sustainably release Li ions to recompense the ionic flux of electrolytes,decreasing the growth of lithium dendrites.The stretched molecular channels can also accelerate the transport of Li ions.The combined effects enable a high Coulombic efficiency of 97.0%for 250 cycles in lithium(Li)||copper(Cu)cell and a stable symmetric plating/stripping behavior over 2000 h at 3 mA cm^(-2)with ultrahigh Li utilization of 50%.Furthermore,the full cell coupled with PHL-Cu@Li anode and Li Fe PO_(4) cathode exhibits long-term cycle stability with high-capacity retention of 95.9%after 900 cycles.Impressively,the full cell paired with LiNi_(0.87)Co_(0.1)Mn_(0.03)O_(2)maintains a discharge capacity of 170.0 mAh g^(-1)with a capacity retention of 84.3%after 100 cycles even under harsh condition of ultralow N/P ratio of 0.83.This facile strategy will widen the potential application of LiNO_(3)in ester-based electrolyte for practical high-voltage LMBs.Haofan Duan Yu You Gang Wang Xiangze Ou Jin Wen Qiao Huang Pengbo Lyu Yaru Liang Qingyu Li Jianyu Huang Yun‑Xiao Wang Hua‑Kun Liu Shi Xue Dou Wei‑Hong Lai 2024Nano-Micro Letters2024,16,4:0
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