|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 辽东半岛早白垩世伸展构造组合、形成时代及区域构造内涵显示文摘辽东半岛地区广泛发育了多种不同类型的伸展构造,包括伸展断陷盆地(通远堡、本溪和丹东)、拆离断层(大营子)和变质核杂岩(辽南和万福),它们具有宏观一致性但却表现出一定的差异.西部地区,结伴发育了两个共用同一下盘的变质核杂岩—辽南和万福变质核杂岩;中东部地区发育了大营子拆离断层系;东部地区广泛发育了多个伸展断陷盆地.对于伸展构造相关的同构造侵入岩与伸展断陷盆地火山岩的年代学分析揭示出伸展构造总体发育于135~106Ma之间,但是各个伸展构造发育时间有一定的差异.伸展构造具有运动学统一性、几何学上的不对称性和构造-岩浆共同活动性;它们在形成时间上具有差异性与跨越性,区域产状变化与切割深度的不一致性;伸展构造宏观上构成共轭组合,但单个伸展构造却具有不对称性.华北、东北、华南乃至蒙古和俄罗斯远东地区的早白垩世伸展构造与辽东半岛地区伸展构造的发育具有统一的组合规律,可以认为辽东半岛地区伸展构造的发育是东亚早白垩世伸展构造域的缩影.Izanagi板块与欧亚板块之间的交互作用以及东亚地区岩石圈结构调整、深部流体活动性和壳幔拆离作用是制约东亚地区早白垩世伸展构造发育的重要因素. | 刘俊来 纪沫 申亮 关会梅 Gregory A DAVIS | 2011 | 中国科学:地球科学2011，41，5： | 52 |
| 2 | Early Cretaceous extensional structures in the Liaodong Peninsula:Structural associations,geochronological constraints and regional tectonic implications显示文摘Various extensional structures,e.g.,half grabens,detachment faults,and metamorphic core complexes,were formed in the Liaodong Peninsula.There are two metamorphic core complexes (mcc's) in the western part of the Peninsula,i.e.the Liaonan mcc and the Wanfu mcc.They share the same lower plate and constitute a conjugate mcc pair.The Dayingzi detachment fault system and the three half grabens are exposed in the central and eastern parts,respectively.U-Pb dating of zircons from syntectonic plutons in the lower plates of the detachment faults and volcanic rocks from half graben basins indicates that their formation spans from 135 to 106 Ma,although the individual structure may be formed at a particular stage.Despite the differences in age of formation,in the regional attitudes,and in rooting depths,the extensional structures have great similarities in their kinematics,geometrical asymmetry,and coeval tectono-magmatic activities etc.Macroscopically,the extensional structures constitute conjugate associations,but a particular one generally has asymmetric patterns.Early Cretaceous extensional structures extend from the Liaodong Peninsula to North China,Northeast China,South China,and eastern Mongolia and Transbaikal area in Russia.The extensional structures from different areas share many common features.The Liaodong Peninsula is the miniature of the East Asia with respect to the formation of extensional structures in Early Cretaceous.It is suggested that the interaction of the Izanagi Plate with Eurasia Plate is responsible for the extension of crust.The structural mobility of the lithosphere,partly attributed to the fluid flow at the depth,and detachment faulting in both the crustal and mantle lithosphere provide important constraints on the development of Early Cretaceous extensional structures in the East Asia. | LIU JunLai JI Mo SHEN Liang GUAN HuiMei Gregory A DAVIS | 2011 | Science China Earth Sciences2011，54，6： | 38 |
| 3 | Coarctation of the aorta:Management from infancy to adulthood显示文摘Coarctation of the aorta is a relatively common form of congenital heart disease, with an estimated incidence of approximately 3 cases per 10000 births. Coarctation is a heterogeneous lesion which may present across all age ranges, with varying clinical symptoms, in isolation, or in association with other cardiac defects. The first surgical repair of aortic coarctation was described in 1944, and since that time, several other surgical techniques have been developed and modified. Additionally, transcatheter balloon angioplasty and endovascular stent placement offer less invasive approaches for the treatment of coarctation of the aorta for some patients. While overall morbidity and mortality rates are low for patients undergoing intervention for coarctation, both surgical and transcatheter interventions are not free from adverse outcomes. Therefore, patients must be followed closely over their lifetime for complications such as recoarctation, aortic aneurysm, persistent hypertension, and changes in any associated cardiac defects. Considerable effort has been expended investigating the utility and outcomes of various treatment approaches for aortic coarctation, which are heavily influenced by a patient's anatomy, size, age, and clinical course. Here we review indications for intervention, describe and compare surgical and transcatheter techniques for management of coarctation, and explore the associated outcomes in both children and adults. | Rachel D Torok Michael J Campbell Gregory A Fleming Kevin D Hill | 2015 | World Journal of Cardiology2015，7，11： | 27 |
| 4 | 辽东半岛大营子拆离断层系及其区域构造意义显示文摘华北克拉通晚中生代发生了大规模岩石圈减薄并伴随着地壳层次区域性伸展作用的发生.在此伸展背景下,华北克拉通区发育有一系列的伸展构造,大营子拆离断层系即为一个典型实例、大营子拆离断层系位于华北克拉通东部(辽东半岛东南部),主要由上盘火山-沉积盆地,大营子-黄花甸拆离断层带以及下盘古元古代变质岩系和侵入岩体三部分组成.依据拆离断层带中构造岩组合、构造岩变形显微构造和石英EBSD组构分析揭示出下盘岩石主要经历了从高绿片岩相到低绿片岩相的变形变质过程.基于火山-沉积盆地中火山岩的SHRIMP和LA-ICP-MS锆石U-Pb测年结果,推断伸展构造开始活动于(135±1.2)Ma之前,结束于(127±1)Ma.通过与辽南变质核杂岩及辽东半岛其他伸展构造的对比,以及这些伸展构造的分布及影响深度,可充分说明辽东半岛岩石圈破坏和减薄的不均一性,从而显示出其破坏程度的差异,并藉此探讨了华北克拉通破坏和伸展减薄的不均匀性. | 申亮 刘俊来 胡玲 纪沫 关会梅 Gregory A DAVIS | 2011 | 中国科学:地球科学2011，41，4： | 24 |
| 5 | The Dayingzi detachment fault system in Liaodong Peninsula and its regional tectonic significance显示文摘Large scale lithosphere thinning is an important characteristic of the destruction of the North China Craton (NCC) during the late Mesozoic. A series of extensional structures were developed under extensional setting, among which is the Dayingzi detachment fault system (DFS). The DFS is constituted by three parts, volcano-sedimentary basins at the hanging wall, the Dayingzi-Huanghuadian detachment fault zone, and Paleoproterozoic metamorphic rock series and Mesozoic plutons at the foot-wall. In the section across the detachment fault zone, there is a sequence of tectonites including fault gouge, microbreccia, cataclastic-mylonites, mylonites, and gneissic biotite monzonite granite. Microstructural characteristics of tectonites and electron backscatter diffraction (EBSD) patterns of quartz indicate that the rocks from the footwall experienced a process from upper greenschist facies to lower greenschist facies. SHRIMP and LA-ICP MS U-Pb dating of zircons from the volcanic rocks in the basins, the tectonic evolution of the DFS is summarized as follows: 1) regional extension started at 135.0±1.2 Ma ago, when the detachment fault cut through the middle crust. Faulting induced the upwelling of magma and eruption of volcanic rocks and deformed a series of medium-acid volcanic rocks; 2) after 135.0±1.2 Ma, a large scale detachment faulting was active cross-cutting the mid-upper crust. The western margin of Jurassic and Triassic granite was ductilly and brittly sheared; besides, the Cretaceous volcano-sedimentary rocks were tilted when the master fault approached the surface; 3) at around 127±1 Ma, the detachment fault stopped its activity and was intruded by the unsheared Cretaceous granite near Chaoyang. Comparison with the Liaonan metamorphic core complex (MCC) and other extensional structures in Liaodong Peninsula led to a general trend of including three zones in the Peninsula: MCC zone, detachment fault systems (DFS) zone, and half graben zone. MCC commonly cuts through the mid-lower crust, DFS through the mid-upper crust, and half graben through the upper crust. Therefore, development of the extensional structures in Liaodong Peninsula indicates that they are the results of crustal extension and thinning at different crustal levels. They may provide a deep insight into the dynamic mechanism, history of destruction and lithosphere thinning of the North China Craton (NCC). | SHEN Liang LIU JunLai HU Ling JI Mo GUAN HuiMei Gregory A DAVIS | 2011 | Science China Earth Sciences2011，54，10： | 17 |
| 6 | Stereotactic body radiation therapy for non-small cell lung cancer:A review显示文摘Stereotactic body radiation therapy(SBRT) is the treatment of choice for medically inoperable patients with early stage non-small cell lung cancer(NSCLC). A literature search primarily based on PubMed electronic databases was completed in July 2018. Inclusion and exclusion criteria were determined prior to the search, and only prospective clinical trials were included. Nineteen trials from 2005 to 2018 met the inclusion criteria, reporting the outcomes of 1434 patients with central and peripheral early stage NSCLC. Patient eligibility,prescription dose and delivery, and follow up duration varied widely. Threeyears overall survival ranged from 43% to 95% with loco-regional control of up to 98% at 3 years. Up to 33% of patients failed distantly after SBRT at 3 years. SBRT was generally well tolerated with 10%-30% grade 3-4 toxicities and a few treatment-related deaths. No differences in outcomes were observed between conventionally fractionated radiation therapy and SBRT, central and peripheral lung tumors, or inoperable and operable patients. SBRT remains a reasonable treatment option for medically inoperable and select operable patients with early stage NSCLC. SBRT has shown excellent local and regional control with toxicity rates equivalent to surgery. Decreasing fractionation schedules have been consistently shown to be both safe and effective. Distant failure is common, and chemotherapy may be considered for select patients. However, the survival benefit of additional interventions, such as chemotherapy, for early stage NSCLC treated with SBRT remains unclear. | Kavitha M Prezzano Sung Jun Ma Gregory M Hermann Charlotte I Rivers Jorge A Gomez-Suescun Anurag K Singh | 2019 | World Journal of Clinical Oncology2019，10，1： | 10 |
| 7 | Optimizing hepatitis C virus treatment through pharmacist interventions: Identification and management of drug-drug interactions显示文摘AIM To quantify drug-drug-interactions(DDIs) encountered in patients prescribed hepatitis C virus(HCV) treatment, the interventions made, and the time spent in this process.METHODS As standard of care, a clinical pharmacist screened for DDIs in patients prescribed direct acting antiviral(DAA) HCV treatment between November 2013 and July 2015 at the University of Colorado Hepatology Clinic. HCV regimens prescribed included ledipasvir/sofosbuvir(LDV/SOF), paritaprevir/ritonavir/ombitasvir/dasabuvir(OBV/PTV/r + DSV), simeprevir/sofosbuvir (SIM/SOF), and sofosbuvir/ribavirin (SOF/RBV). This retrospective analysis reviewed the work completed by the clinical pharmacist in order to measure the aims identified for the study. The number and type of DDIs identified were summarized with descriptive statistics.RESULTS Six hundred and sixty four patients(83.4% Caucasian, 57% male, average 56.7 years old) were identified; 369 for LDV/SOF, 48 for OBV/PTV/r + DSV, 114 for SIM/SOF, and 133 for SOF/RBV. Fifty-one point five per cent of patients were cirrhotic. Overall, 5217 medications were reviewed (7.86 medications per patient) and 781 interactions identified (1.18 interactions per patient). The number of interactions were fewest for SOF/RBV (0.17 interactions per patient) and highest for OBV/PTV/r + DSV (2.48 interactions per patient). LDV/SOF and SIM/SOF had similar number of interactions (1.28 and 1.48 interactions per patient, respectively). Gastric acid modifiers and vitamin/herbal supplements commonly caused interactions with LDV/SOF. Hypertensive agents, analgesics, and psychiatric medications frequently caused interactions with OBV/PTV/r + DSV and SIM/SOF. To manage these interactions, the pharmacists most often recommended discontinuing the medication (28.9%), increasing monitoring for toxicities (24.1%), or separating administration times (18.2%). The pharmacist chart review for each patient usually took approximately 30 min, with additional time for more complex patients. CONCLUSION DDIs are common with HCV medications and management can require medication adjustments and increased monitoring. An interdisciplinary team including a clinical pharmacist can optimize patient care. | Jacob A Langness Matthew Nguyen Amanda Wieland Gregory T Everson Jennifer J Kiser | 2017 | World Journal of Gastroenterology2017，23，9： | 5 |
| 8 | Computed tomography-based diagnostics might be insufficient in the determination of pancreatic cancer unresectability显示文摘AIM: To inquire into a question of an overestimation of arterial involvement in patients with pancreatic cancer (PC). METHODS: Radiology data were compared with the findings from 51 standard, 58 extended and 17 total pancreaticoduodenectomies; 9 distal resections with celiac artery (CA) excision; and 28 palliations for PC. The survival of 11 patients with controversial computed tomography (CT) and endoscopic ultrasound data with regard to arterial invasion, after R0/R1 procedures (false-positive CT results, Group A), was compared to survival after eight R2 resections (false-negative CT results, Group B) and after 12 bypass procedures for locally advanced cancer (true-positive CT results, Group C).RESULTS: In all of the cases in group A, operative exploration revealed no arterial invasion, which was predicted by CT. The one-year survival in Group A was 88.9%, and the two-year survival was 26.7%, with a median follow-up of 22 mo. One-year survival was not attained in groups B and C, with a significant difference in survival (P a-b = 0.0029, P b-c = 0.003).CONCLUSION: Arterial encasement on CT does not necessarily indicate arterial invasion. Whenever PC is considered unresectable, endoUS should be used. In patients with controversial CT an EUS data for peripan-creatic arteries involvement radical resection might be possible, providing survival benefits as compared to R2-resections or palliative surgery. | Vyacheslav I Egorov Roman V Petrov Elena N Solodinina Gregory G Karmazanovsky Natalia S Starostina Natalia A Kuruschkina | 2013 | World Journal of Gastrointestinal Surgery2013，5，4： | 4 |
| 9 | Uterine biology in pigs and sheep显示文摘There is a dialogue between the developing conceptus (embryo-fetus and associated placental membranes) and maternal uterus which must be established during the peri-implantation period for pregnancy recognition signaling, implantation, regulation of gene expression by uterine epithelial and stromal cells, placentation and exchange of nutrients and gases. The uterus provide a microenvironment in which molecules secreted by uterine epithelia or transported into the uterine lumen represent histotroph required for growth and development of the conceptus and receptivity of the uterus to implantation. Pregnancy recognition signaling mechanisms sustain the functional lifespan of the corpora lutea (CL) which produce progesterone, the hormone of pregnancy essential for uterine functions that support implantation and placentation required for a successful outcome of pregnancy. It is within the peri-implantation period that most embryonic deaths occur due to deficiencies attributed to uterine functions or failure of the conceptus to develop appropriately, signal pregnancy recognition and/or undergo implantation and placentation. With proper placentation, the fetal fluids and fetal membranes each have unique functions to ensure hematotrophic and histotrophic nutrition in support of growth and development of the fetus. The endocrine status of the pregnant female and her nutritional status are critical for successful establishment and maintenance of pregnancy. This review addresses the complexity of key mechanisms that are characteristic of successful reproduction in sheep and pigs and gaps in knowledge that must be the subject of research in order to enhance fertility and reproductive health of livestock species. | Fuller W Bazer Gwonhwa Song Jinyoung Kim Kathrin A Dunlap Michael Carey Satterfield Gregory A Johnson Robert C Burghardt Guoyao Wu | 2012 | Journal of Animal Science and Biotechnology2012，3，3： | 3 |
| 10 | Validity and Reliability of the Reflux Symptom Index (RSI)显示文摘 | Peter C Belafsky Gregory N Postma James A Koufman | 2002 | Journal of Voice2002，，2： | 3 |
| 11 | A randomized, double blind study of interleukin 10 for the prevention of ERCP-induced pancreatitis显示文摘 | John A Dumot Darwin L Conwell Gregory Zuccaro John J Vargo Steven S Shay Kirk A Easley Jeffrey L Ponsky | 2001 | The American Journal of Gastroenterology2001，，7： | 2 |
| 12 | Space radiation and cardiovascular disease risk显示文摘Future long-distance space missions will be associated with significant exposures to ionizing radiation,and the health risks of these radiation exposures during manned missions need to be assessed. Recent Earth-based epidemiological studies in survivors of atomic bombs and after occupational and medical low dose radiation exposures have indicated that the cardiovascular system may be more sensitive to ionizing radiation than was previously thought. This has raised the concern of a cardiovascular disease risk from exposure to space radiation during long-distance space travel. Groundbased studies with animal and cell culture models play an important role in estimating health risks from space radiation exposure. Charged particle space radiation has dense ionization characteristics and may induce unique biological responses,appropriate simulation of the space radiation environment and careful consideration of the choice of the experimental model are critical. Recent studies have addressed cardiovascular effects of space radiation using such models and provided first results that aid in estimating cardiovascular disease risk,and several other studies are ongoing. Moreover,astronauts could potentially be administered pharmacological countermeasures against adverse effects of space radiation,and research is focused on the development of such compounds. Because the cardiovascular response to space radiation has not yet been clearly defined,the identification of potential pharmacological countermeasures against cardiovascular effects is still in its infancy. | Marjan Boerma Gregory A Nelson Vijayalakshmi Sridharan Xiao-Wen Mao Igor Koturbash Martin Hauer-Jensen | 2015 | World Journal of Cardiology2015，7，12： | 2 |
| 13 | 原位肝移植33例肝动脉及门静脉吻合的体会显示文摘 | 秦锡虎 Williiam Kenneth Washburn Robert Esterl Gregory Abrahamian Glenn A Halff | 2005 | 中华外科杂志2005，43，5： | 2 |
| 14 | Effects of surgery, general anesthesia, and perioperative epidural analgesia on the immune function of patients with non-small cell lung cancer显示文摘 | Juan P. Cata Maria Bauer Telemate Sokari María F. Ramirez David Mason Gregory Plautz Andrea Kurz | 2013 | Journal of Clinical Anesthesia2013，，： | 2 |
| 15 | 一名美国地质学家对中国地球科学和教育的思考显示文摘本文是格瑞高利·艾伦·戴维斯在中国地质大学(北京)为他举办的70华诞生日庆祝会上的讲话,由马文璞教授翻译整理而成。文章在充分肯定中国地质学在政府的支持下取得长足进步的同时,也对中国地学教育、科研状况提出中肯的批评和友好的建议。 | Gregory A Davis | 2006 | 中国地质教育2006，15，1： | 2 |
| 16 | Aflatoxin Exposure and Viral Hepatitis in the Etiology of Liver Cirrhosis in The Gambia, West Africa显示文摘 | Kuniholm Mark H Lesi Olufunmilayo A Mendy Maimuna Akano Aliu O Sam Omar Hall Andrew J Whittle Hilton Bah Ebrima Goedert James J Hainaut Pierre Kirk Gregory D | 2008 | Environmental Health Perspectives2008，，11： | 2 |
| 17 | Atrial fibrillation显示文摘 | Gregory YH Lip Hung Fat Tse Deirdre A Lane | 2012 | The Lancet . 2012 (9816)2012，，： | 2 |
| 18 | Advances in the Treatment and Outcome of Brainstem Cavernous Malformation Surgery: A Single-Center Case Series of 300 Surgically Treated Patients显示文摘 | Adib A Abla Gregory P Lekovic Jay D Turner Jean G de Oliveira Randall Porter Robert F Spetzler | 2011 | Neurosurgery2011，，2： | 2 |
| 19 | Role of autophagy in gastric carcinogenesis显示文摘Gastric cancer represents a common and highly fatal malignancy,and thus a pathophysiology-based reconsideration is necessary,given the absence of efficient therapeutic regimens.In this regard,emerging data reveal a significant role of autophagy in gastric oncogenesis,progression,metastasis and chemoresistance.Although autophagy comprises a normal primordial process,ensuring cellular homeostasis under energy depletion and stress conditions,alterations at any stage of the complex regulatory system could stimulate a tumorigenic and promoting cascade.Among others,Helicobacter pylori infection induces a variety of signaling molecules modifying autophagy,during acute infection or after chronic autophagy degeneration.Subsequently,defective autophagy allows malignant transformation and upon cancer establishment,an overactive autophagy is stimulated.This overexpressed autophagy provides energy supplies and resistance mechanisms to gastric cancer cells against hosts defenses and anticancer treatment.This review interprets the implicated autophagic pathways in normal cells and in gastric cancer to illuminate the potential preventive,therapeutic and prognostic benefits of understanding and intervening autophagy. | Apostolis Papaefthymiou Gregory Christodoulidis Apostolos Koffas Michael Doulberis Stergios A Polyzos Anastasios Manolakis Spyros Potamianos Andreas Kapsoritakis Jannis Kountouras | 2021 | World Journal of Gastrointestinal Oncology2021，13，10： | 2 |
| 20 | Evaluation of the analgesic activity of ethyl acetate,methanol and aqueous extracts of Pleurotus eous mushroom显示文摘Objective:To evaluate the analgesic activity of the ethyl acetate,methanol and aqueous extracts of Plewotus eous(P.eous) mushroom.Methods:The dried fruiting bodies were extracted with ethyl acetate,methanol and water.The analgesic effect of extracts of P.eous were investigated at doses 250 500 and 1 000 mg/kg body weight,using acetic-acid induced writhing,hot-plate,tail immersion and tail-clip tests.Results:P.eous extracts produced significant reduction in number of writhes induced by intraperitoneal injection of acetic-acid(P<0.05).Moreover,in hot-plate and tail immersion test,all the three extracts significantly raised the pain threshold at different time of observation(0-60 min) in comparison with control(P<0.05).In tail-clip test the extracts also caused a significant inhibition of pain at both the doses used(P<0.05).Conclusions:The results of present study suggest that extracts of P.eous possess potent analgesic property and could serve as a base for future drugs. | Suseem SR Mary Saral A Neelakanda Reddy P Marslin Gregory | 2011 | Asian Pacific Journal of Tropical Medicine2011，4，2： | 2 |
您所在的机构暂未开通此部分的功能，请联系管理员