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| 1 | Lesion-symptom mapping with NIHSS sub-scores in ischemic stroke patients显示文摘Background Lesion-symptom mapping(LSM)is a statistical technique to investigate the population-specific relationship between structural integrity and post-stroke clinical outcome.In clinical practice,patients are commonly evaluated using the National Institutes of Health Stroke Scale(NIHSS),an 11-domain clinical score to quantitate neurological deficits due to stroke.So far,LSM studies have mostly used the total NIHSS score for analysis,which might not uncover subtle structure–function relationships associated with the specific sub-domains of the NIHSS evaluation.Thus,the aim of this work was to investigate the feasibility to perform LSM analyses with sub-score information to reveal category-specific structure–function relationships that a total score may not reveal.Methods Employing a multivariate technique,LSM analyses were conducted using a sample of 180 patients with NIHSS assessment at 48-hour post-stroke from the ESCAPE trial.The NIHSS domains were grouped into six categories using two schemes.LSM was conducted for each category of the two groupings and the total NIHSS score.Results Sub-score LSMs not only identify most of the brain regions that are identified as critical by the total NIHSS score but also reveal additional brain regions critical to each function category of the NIHSS assessment without requiring extensive,specialised assessments.Conclusion These findings show that widely available sub-scores of clinical outcome assessments can be used to investigate more specific structure–function relationships,which may improve predictive modelling of stroke outcomes in the context of modern clinical stroke assessments and neuroimaging. | Deepthi Rajashekar Matthias Wilms M Ethan MacDonald Serena Schimert Michael D Hill Andrew Demchuk Mayank Goyal Sean P Dukelow Nils Daniel Forkert | 2022 | Stroke & Vascular Neurology2022，7，2： | 7 |
| 2 | JAMA:急性缺血性卒中血管内治疗的时间窗为7.3?h显示文摘2015年发表在NEJM上的5项大动脉闭塞急性缺血性卒中血管内治疗的随机试验证实第二代血管内再通治疗装置(主要是支架取栓装置)优于单独内科治疗。但是目前尚不清楚症状超过6 h患者血管内治疗的风险和获益,同样也不清楚发病6 h内获益的程度和时间之间的关系。美国、欧洲和加拿大国家指南推荐血管内治疗的时间窗为6 h,但是美国食品和药品管理局推荐时间窗为8 h,加拿大指南补充认为时间窗可达12 h。 | 杨中华 Saver JL Goyal M van der Lugt A | 2017 | 中国卒中杂志2017，12，1： | 4 |
| 3 | Optimal ordering decisions for two substitutable products with stochastic demands显示文摘 | Parlar M Goyal S K | 1984 | Operational Research1984，21，： | 1 |
| 4 | Development and characterization of effective topical liposomal system for localized treatment of cutaneous candidiasis显示文摘 | Gupta M Goyal AK Paliwal SR | 2010 | J Liposome Res2010，20，4： | 1 |
| 5 | Direct synthesis of diphenyl carbonate by oxidative carbonylation of phenol using Pd-Cu based redox catalyst system显示文摘 | Goyal M Nagahata R Sugiyama J | 1999 | J Mol Catal A:Chem1999，137，123： | 1 |
| 6 | Discrete analysis of plasma oxalate with alkylamine glass bound sorghum oxalate oxidase and horseradish peroxidase显示文摘 | Thakur M Goyal L Pundir CS | 2000 | J Biochem Biophys Methods2000，44，： | 1 |
| 7 | Detection of porcine reproductive and respiratory syndrome virus by reverse transcrip- tion-polymerase chain reaction using different regions of the viral genome显示文摘 | Guarino H Goyal S M Murtaugh M P | 1999 | J Vet Diagn Invest1999，11，1： | 1 |
| 8 | Hypertrophic olivary degen- eration: metaanalysis of the temporal evolution of MR find- ings 显示文摘 | Goyal M Versnick E Tuite P | 2000 | Am J Neuroradiol2000，21，6： | 1 |
| 9 | Relationship be- tween spontaneous and iatrogenic hypoglycemia and mortality in patients hospitalized with acute myocardial infarction 显示文摘 | Kosiborod M Inzucchi SE Goyal A | 2009 | JA- MA2009，301，15： | 1 |
| 10 | A hybrid Taguchi-Immune approach to optimize an integrated sup- ply chain design problem with multiple shipping显示文摘 | Tiwari M K Raghavendra N Goyal S K | 2010 | European Journal of Operational Research2010，203，1： | 1 |
| 11 | Data Models in Geographic Information Systems显示文摘 | Shekhar S Coyle M Goyal B | 1997 | Commun ACM1997，40，4： | 1 |
| 12 | Meta-analysis and review on the effect of bevacizumab in diabetic macular edema显示文摘 | Goyal S Lavalley M Subramanian ML | 2011 | Graefes Arch Exp Ophthal2011，249，1： | 1 |
| 13 | A cytohistological study of Ki-67 expression in ovarian tumors显示文摘 | CHOUDHURY M GOYAL S PUJANI M | 2011 | Indian J Pathol Microbiol2011，54，1： | 1 |
| 14 | Growth of biaxially textured buffer layers on rolled-Ni substrates by electron beam evaporation显示文摘 | Paranthaman M Goyal A List F A | 1997 | Physica C1997，275，： | 1 |
| 15 | Economic and health consequences of selling a kidney in India显示文摘 | GOYAL M MEHETA R L SCHEIDERMAN L J | 2002 | JAMA2002，288，3： | 1 |
| 16 | An OSPF Topology Server: Design and Evalu- ation 显示文摘 | SHAIKH A GOYAL M | 2002 | IEEE Journal on Selected Areas in Communications2002，20，4： | 1 |
| 17 | Clinical applications of targeted temperature management显示文摘 | Perman SM Goyal M Neumar RW | 2014 | Chest2014，145，2： | 1 |
| 18 | Inherited metabolic disorders involving the eye:a clinico-biochemical perspective显示文摘 | Rajappa M Goyal A Kaur J | | 0，，： | 1 |
| 19 | Aerobic glycolysis in the human brain is associated with development and neotenous gene expression显示文摘 | Goyal MS Hawrylyez M Miller JA | 2014 | CellMetab2014，19，1： | 1 |
| 20 | Chronological immunohitochemical detection and localization of porcine reproductive and respiratory syndrome vires infection in gnotobiotic pigs显示文摘 | ROSSOW D BENFIELD D A GOYAL S M | 1996 | Vet Pathol1996，33，： | 1 |
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