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5篇 您的检索式：作者名="Gil Ast"

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		题名	作者	年代	出处	被引量
	1	Phosphatidylserine improves axonal transport by inhibition of HDAC and has potential in treatment of neurodegenerative diseases显示文摘Familial dysautonomia(FD) is a rare children neurodegenerative disease caused due to a point mutation in the IKBKAP gene that results in decreased IKK complex-associated protein(IKAP) protein production. The disease affects mostly the dorsal root ganglion(DRG) and the sympathetic ganglion. Recently, we found that the molecular mechanisms underlying neurodegeneration in FD patients are defects in axonal transport of nerve growth factors and microtubule stability in the DRG. Neurons are highly polarized cells with very long axons. In order to survive and maintain proper function, neurons depend on transport of proteins and other cellular components from the neuronal body along the axons. We further demonstrated that IKAP is necessary for axon maintenance and showed that phosphatidylserine acts as an HDAC6 inhibitor to rescue neuronal function in FD cells. In this review, we will highlight our latest research findings.	Shiran Naftelberg Gil Ast Eran Perlson	2017	Neural Regeneration Research2017，12，4：	2
	2	Insights into the connection between cancer and alternative splicing显示文摘	Eddo Kim Amir Goren Gil Ast	2007	Trends in Genetics2007，，1：	1
	3	Differential GC Content between Exons and Introns Establishes Distinct Strategies of Splice-Site Recognition显示文摘	Maayan Amit Maya Donyo Dror Hollander Amir Goren Eddo Kim Sahar Gelfman Galit Lev-Maor David Burstein Schraga Schwartz Benny Postolsky Tal Pupko Gil Ast	2012	Cell Reports2012，，5：	1
	4	Alternative Splicing Regulates Biogenesis of miRNAs Located across Exon-Intron Junctions显示文摘	Ze’ev Melamed Asaf Levy Reut Ashwal-Fluss Galit Lev-Maor Keren Mekahel Nir Atias Shlomit Gilad Roded Sharan Carmit Levy Sebastian Kadener Gil Ast	2013	Molecular Cell2013，，6：	1
	5	基因剪接花样多显示文摘2000年春天,一些基础分子生物学家互相打赌,试图预测DNA测序完成后在人类基因组中所能发现的基因数目.那时估计的基因数最高达到15.3万个.毕竟在大多数人看来,人类要产生大约9万种不同类型的蛋白质,因此我们需要至少同样多的基因来编码它们.	Gil Ast 李贵森曾少立	2005	科学(中文版)2005，，6：	0

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