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| 1 | Acute appendicitis: Epidemiology, treatment and outcomesanalysis of 16544 consecutive cases显示文摘AIM To investigate the epidemiology,treatment and outcomes of acute appendicitis(AA) in a large population study.METHODS This is a retrospective cohort study derived from the administrative dataset of the Bergamo district healthcare system(more than 1 million inhabitants) from 1997 to 2013.Data about treatment,surgery,length of stay were collected.Moreover for each patients were registered data about relapse of appendicitis and hospital admission due to intestinal obstruction.RESULTS From 1997 to 2013 in the Bergamo district we collected 16544 cases of AA,with a crude incidence rate of 89/100000 inhabitants per year; mean age was 24.51 ± 16.17,54.7% were male and the mean Charlson's comorbidity index was 0.32 ± 0.92.Mortality was < 0.0001%.Appendectomy was performed in 94.7% of the patients and the mean length of stay was 5.08 ± 2.88 d; the cumulative hospital stay was 5.19 ± 3.36 d and 1.2% of patients had at least one further hospitalization due intestinal occlusion.Laparoscopic appendectomy was performed in 48% of cases.Percent of 5.34 the patients were treated conservatively with a mean length of stay of 3.98 ± 3.96 d; the relapse rate was 23.1% and the cumulative hospital stay during the study period was 5.46 ± 6.05 d.CONCLUSION The treatment of acute appendicitis in Northern Italy is slowly changing,with the large diffusion of laparoscopic approach; conservative treatment of non-complicated appendicitis is still a neglected option,but rich of promising results. | Marco Ceresoli Alberto Zucchi Niccolò Allievi Asaf Harbi Michele Pisano Giulia Montori Arianna Heyer Gabriela E Nita Luca Ansaloni Federico Coccolini | 2016 | World Journal of Gastrointestinal Surgery2016，8，10： | 14 |
| 2 | The yin and yang of co-inhibitory receptors: toward anti-tumor immunity without autoimmunity显示文摘Co-inhibitory receptors are important regulators of T | Alexandra Schnell Lloyd Bod Asaf Madi Vijay K.Kuchroo | 2020 | Cell Research2020，30，4： | 10 |
| 3 | 药用植物内生菌对作物生长及氧化应激的作用(英文)显示文摘目的:探讨药用植物内生菌的多样性及其在种子生长和氧化应激中的作用。方法:从三种药用植物(Caralluma acutangula、Rhazya stricta和Moringa peregrina)中提取内生菌;基于18S r DNA测序和系统发育分析鉴定分离得到的内生菌株;以正常和矮化突变体水稻品系为对照,比较不同浓度的内生菌培养滤液(CF)对水稻种子的发芽和生长的影响;通过气相色谱-质谱分析CF中的有效活性成分。结论:从药用植物中共获得10种内生菌,包括茎点霉属6株、链格孢属2株、双极霉属1株和枝孢霉属1株。CF表现出剂量依赖性的生长刺激和抑制作用。与对照和其他内生菌相比,100%的茎点霉菌CF显著促进了水稻种子的发芽和生长;双极霉中的吲哚乙酸含量最高,并表现出比其更高的自由基清除和抗脂质过氧化活性;双极霉菌和茎点霉菌的类黄酮和酚类成分较高。综上所述,药用植物中存在内生菌株,其可以用于改善作物生长和减轻氧化应激。 | Abdul Latif KHAN Syed Abdullah GILANI Muhammad WAQAS Khadija AL-HOSNI Salima AL-KHIZIRI Yoon-Ha KIM Liaqat ALI Sang-Mo KANG Sajjad ASAF Raheem SHAHZAD Javid HUSSAIN In-Jung LEE Ahmed AL-HARRASI | 2017 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2017，18，2： | 6 |
| 4 | Etiology and long-term outcome of extrahepatic portal vein obstruction in children显示文摘AIM:To study the management and outcome of children with extrahepatic portal vein obstruction(EHPVO) in a whole country population.METHODS:A nationwide multicenter retrospective case series of children with EHPVO was conducted.Data on demographics,radiographic studies,laboratory workup,endoscopic and surgical procedures,growth and development,were extracted from the patients' charts.Characteristics of clinical presentation,etiology of EHPVO,management and outcome were analyzed.RESULTS:Thirty patients,13 males and 17 females,19(63.3%) Israeli and 11(36.7%) Palestinians,were included in the analysis.Age at presentation was 4.8± 4.6 years,and mean follow-up was 4.9±4.3 years.Associated anomalies were found in 4 patients.The incidence of EHPVO in Israeli children aged 0-14 years was 0.72/million.Risk factors for EHPVO were detected in 13(43.3%)patients,including 9 patients(30%) with perinatal risk factors,and 4 patients(13.3%) with prothrombotic states:two had low levels of protein S and C,one had lupus anticoagulant,and one was homozygous for methyltetrahydrofolate reductase mutations.In 56.6% of patients,no predisposing factors were found.The most common presenting symptoms were an incidental finding of splenomegaly(43.3%),and upper gastrointestinal bleeding(40%).No differences were found between Israeli and Palestinian children with regard to age at presentation,etiology and clinical symptoms.Bleeding occurred in 18 patients(60%),at a median age of 3 years.Sclerotherapy or esophageal banding was performed in 20 patients.No sclerotherapy complications were reported.Portosystemic shunts were performed in 11 patients(36.6%),at a median age of 11(range 3-17)years:splenorenal in 9,mesocaval in 1,and a meso-Rex shunt in 1 patient.One patient underwent splenectomy due to severe pancytopenia.Patients were followed up for a median of 3(range 0.5-15)years.One patient died aged 3 years due to mucopolysaccharidase deficiency type Ⅲ.None of the patients died due to gastrointestinal bleeding.CONCLUSION:EHPVO is a rare disorder.The etiological factors are still mostly unknown,and the endoscopic and surgical treatment options ensure a good long-term prognosis. | Batia Weiss Eyal Shteyer Asaf Vivante Drora Berkowitz Shimon Reif Zvi Weizman Yoram Bujanover Rivka Shapiro | 2010 | World Journal of Gastroenterology2010，16，39： | 6 |
| 5 | Conf irmation of endotracheal tube placement using disposable f iberoptic bronchoscopy in the emergent setting显示文摘BACKGROUND:Patients intubated in the prehospital setting require quick and definitive confirmation of endotracheal (ET) tube placement upon arrival to the emergency department (ED).Direct and adjunct strategies exist,but each has limitations and there is no definitive gold standard.The utility of bronchoscopy in ED intubation has been studied,but scant literature exists on its use for ET tube confirmation.This study aims to assess effectiveness,ease and speed with which ET tube placement can be confirmed with disposable fiberoptic bronchoscopy.METHODS:Emergency medicine residents recruited from a 3-year urban residency program received 5 minutes of active learning on a simulation mannequin using a disposable,flexible Ambu aScope interfaced with a monitor.With residents blinded,the researcher randomly placed the ET tube in the trachea,esophagus or right mainstem.Residents identified ET tube position by threading the bronchoscope through the tube and viewing distal anatomy.Each resident underwent 4 trials.Accuracy,speed and perceptions of difficulty were measured.RESULTS:Residents accurately identified the location of the ET tube in 88 out of 92 trials (95.7%).The median time-to-guess was 7.0 seconds,IQR (5.0-10.0).Average perceived difficulty was 1.6 on a scale from 1-5 (1 being very easy and 5 being very difficult).No tubes were damaged or dislodged.CONCLUSION:While simulation cannot completely replicate the live experience,fiberoptic bronchoscopy appears to be a quick and accurate method for ET tube confirmation.Further studies directly comparing this novel approach to established practices on actual patients are warranted. | Avir Mitra Asaf Gave Kelsey Coolahan Thomas Nguyen | 2019 | World Journal of Emergency Medicine2019，10，4： | 5 |
| 6 | Biosorption potential of cerium ions using Spirulina biomass显示文摘Two types of cyanobacteria of the genus Arthrospira(commonly known as Spirulina) were tested for biosorption of cerium(III) ions from aqueous solutions. An endemic type(ES) found in the northern Negev desert, Israel, and a commercial powder(CS) were used in this study. Biosorption was evaluated as a function of p H, contact time, initial metal concentration, number of sorption-desorption cycles, and salt concentration. The optimum p H range for biosorption was found to be 5.0–5.5. The kinetic characteristics of both Spirulina types were found to be highly compatible with a pseudo-second order kinetic model. The adsorption isotherms of both types were found to be well-suited to Langmuir and Freundlich adsorption isotherms. Maximum biosorption uptakes, according to the Langmuir model, were 18.1 and 38.2 mg/g, for ES and CS, respectively. Sodium chloride concentrations of up to 5 g/L had a minor effect on cerium biosorption. Desorption efficiency was found to be greater than 97% with 0.1 mol/L HNO_3 after three sorption-desorption cycles, without significant loss in the biosorption capacity. The results indicated the feasibility of cerium recovery from industrial wastes using Spirulina biomass. | David Sadovsky Asher Brenner Boaz Astrachan Boaz Asaf Raphael Gonen | 2016 | Journal of Rare Earths2016，34，6： | 4 |
| 7 | ConfDTree: A Statistical Method for Improving Decision Trees显示文摘Decision trees have three main disadvantages: reduced performance when the training set is small; rigid decision criteria; and the fact that a single 'uncharacteristic' attribute might 'derail' the classification process. In this paper we present ConfDTree(Confidence-Based Decision Tree) — a post-processing method that enables decision trees to better classify outlier instances. This method, which can be applied to any decision tree algorithm, uses easy-to-implement statistical methods(confidence intervals and two-proportion tests) in order to identify hard-to-classify instances and to propose alternative routes. The experimental study indicates that the proposed post-processing method consistently and significantly improves the predictive performance of decision trees, particularly for small, imbalanced or multi-class datasets in which an average improvement of 5%~9% in the AUC performance is reported. | Gilad Katz Asaf Shabtai Lior Rokach Nir Ofek | 2014 | Journal of Computer Science & Technology2014，29，3： | 3 |
| 8 | The impact of cemented layers and hardpans on oxygen diffusivity in mining waste heaps A field study of the Halsbrücke lead–zinc mine tailings (Germany)显示文摘 | Claus Kohfahl Torsten Graupner Christian Fetzer Asaf Pekdeger | 2010 | Science of the Total Environment2010，，23： | 2 |
| 9 | Lingua franca: The role of English in international trade显示文摘 | Hyejin Ku Asaf Zussman | 2010 | Journal of Economic Behavior and Organization2010，，2： | 2 |
| 10 | The cognitive neuroscience of remote episodic, semantic and spatial memory显示文摘 | Morris Moscovitch Lynn Nadel Gordon Winocur Asaf Gilboa R Shayna Rosenbaum | 2006 | Current Opinion in Neurobiology2006，，2： | 2 |
| 11 | Growing Epidemic of Coronary Heart Disease in Low- and Middle-Income Countries显示文摘 | Thomas A. Gaziano Asaf Bitton Shuchi Anand Shafika Abrahams-Gessel Adrianna Murphy | 2010 | Current Problems in Cardiology2010，，： | 1 |
| 12 | Interaction between soil and a wide cutting blade using the discrete element method显示文摘 | SHMULEVICH I ASAF Z RUBINSTEIN D | 2007 | Soil & Tillage Research2007，97，1： | 1 |
| 13 | Interaction between soil and a wide cutting blade using the discrete element method显示文摘 | SHMULEVICH I ASAF Z RUBINSTEIN D | 2007 | Soil&Tillage Research2007，97，1： | 1 |
| 14 | Synthesis of higher fatty acid starch esters using vinyl laurate and stearate as reactants显示文摘 | Laura Junistia Asaf K Sugih | | 0，，： | 1 |
| 15 | Acute urinary retention in children 显示文摘 | Marans Rachel Mandel Asaf Gielchinsky Ilan | 2012 | Harefuah2012，151，6： | 1 |
| 16 | Google Android: A comprehensive security asssment 显示文摘 | Asaf Shabtal Yuval Fledel Uri Kanonv | 2010 | IEEE Security and Privacy2010，8，2： | 1 |
| 17 | Thermal history and tectonic subsidence of the Bohai Basin,northern China: a Cenozoic rifted and local pull-apart basin显示文摘 | Hu S B Paul B O′ Sullivan Asaf Raza | 2001 | Physics of the Earth and Planetary Interiors2001，126，： | 1 |
| 18 | Determination of discrete element model parameters required for soil tillage 显示文摘 | ASAF Z RLIBINSTEIN D SHMULEVICH I | 2007 | Soil and Tillage Research2007，92，12： | 1 |
| 19 | Evalu- ation of Link-track Performances Using DEM显示文摘 | ASAF Z RUBINSTEIN D SHMULEVICH I | 2006 | Journal of Terramechanics2006，43，2： | 1 |
| 20 | Growing epidemic of coronary hear disease in low-and middle-income countries显示文摘 | Thomas AG Asaf B Shuchi A | 2010 | Curt Probl Cardiol2010，35，2： | 1 |
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