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| 1 | Preoperative radiotherapy versus selective postoperative chemoradiotherapy in patients with rectal cancer (MRC CR07 and NCIC-CTG C016): a multicentre, randomised trial显示文摘 | David Sebag-Montefiore Richard J Stephens Robert Steele John Monson Robert Grieve Subhash Khanna Phil Quirke Jean Couture Catherine de Metz Arthur Sun Myint Eric Bessell Gareth Griffiths Lindsay C Thompson Mahesh Parmar | 2009 | The Lancet2009，，9666： | 5 |
| 2 | Preoperative radiotherapy versus selective postoperative chemoradiotherapy in patients with rectal cancer (MRC CR07 and NCIC-CTG C016): a multicentre, randomised trial显示文摘 | David Sebag-Montefiore Richard J Stephens Robert Steele John Monson Robert Grieve Subhash Khanna Phil Quirke Jean Couture Catherine de Metz Arthur Sun Myint Eric Bessell Gareth Griffiths Lindsay C Thompson Mahesh Parmar | 2009 | The Lancet2009，，9666： | 3 |
| 3 | Preoperative radiotherapy versus selective postoperative chemoradiotherapy in patients with rectal cancer (MRC CR07 and NCIC-CTG C016): a multicentre, randomised trial显示文摘 | David Sebag-Montefiore Richard J Stephens Robert Steele John Monson Robert Grieve Subhash Khanna Phil Quirke Jean Couture Catherine de Metz Arthur Sun Myint Eric Bessell Gareth Griffiths Lindsay C Thompson Mahesh Parmar | 2009 | The Lancet . 2009 (9666)2009，，9666： | 3 |
| 4 | SLC26A4 mutation testing for hearing loss associated with enlargement of the vestibular aqueduct显示文摘Pendred syndrome(PS) is characterized by autosomal recessive inheritance of goiter associated with a defect of iodide organification, hearing loss, enlargement of the vestibular aqueduct(EVA), and mutations of the SLC26A4 gene. However, not all EVA patients have PSor SLC26A4 mutations. Two mutant alleles of SLC26A4 are detected in 1/4 of North American or European EVA populations, one mutant allele is detected in another 1/4 of patient populations, and no mutations are detected in the other 1/2. The presence of two mutant alleles of SLC26A4 is associated with abnormal iodide organification, increased thyroid gland volume, increased severity of hearing loss, and bilateral EVA. The presence of a single mutant allele of SLC26A4 is associated with normal iodide organification, normal thyroid gland volume, less severe hearing loss and either bilateral or unilateral EVA. When other underlying correlations are accounted for, the presence of a cochlear malformation or the size of EVA does not have an effect on hearing thresholds. This is consistent with observations of an Slc26a4 mutant mouse model of EVA in which hearing loss is independent of endolymphatic hydrops or inner ear malformations. Segregation analyses of EVA in families suggest that the patients carrying one mutant allele of SLC26A4 have a second, undetected mutant allele of SLC26A4, and the probability of a sibling having EVA is consistent with its segregation as an autosomal recessive trait. Patients without any mutations are an etiologically heterogeneous group in which siblings have a lower probability of having EVA. SLC26A4 mutation testing can provide prognostic information to guide clinical surveillance and management, as well as the probability of EVA affecting a sibling. | Taku Ito Julie Muskett Parna Chattaraj Byung Yoon Choi Kyu Yup Lee Christopher K Zalewski Kelly A King Xiangming Li Philine Wangemann Thomas Shawker Carmen C Brewer Seth L Alper Andrew J Griffith | 2013 | World Journal of Otorhinolaryngology2013，3，2： | 2 |
| 5 | Substrate heterogeneity and microfauna in soil organic ‘hotspots' as determinants of nitrogen capture and growth of ryegrass显示文摘 | Bonkowski M Griffiths B and Scrimgeour C | 2000 | Applied Soil Ecology2000，14，： | 2 |
| 6 | Change in pore size distribution due to consolidation of clays显示文摘 | Griffiths F J Joshi R C | 1989 | Gèotechnique1989，39，1： | 2 |
| 7 | A trade–off between reproduction and a condition–dependent sexually selected ornament in the house sparrow Passer domesticus显示文摘 | Griffith S. C | 2000 | Proceedings of the Royal Society B: Biological Sciences . 2000 (1448)2000，，： | 2 |
| 8 | Author co-citation: A literature measure of intellectual structure 显示文摘 | White H Griffith B C | 1981 | Journal of the A- merican Society for Information Science and Technology1981，32，3： | 1 |
| 9 | RhoC-GTPase is a novel tissue biomarker associated with biologically aggressive carcinomas of the breast显示文摘 | Kleer C G Griffith K A Sabel M S | 2005 | Breast Cancer Res Treat2005，93，2： | 1 |
| 10 | Isoniazid prophylaxis for tuberculosis in HIV infection:a meta analysis of randomized controlled trials显示文摘 | Bucher H C Griffith L Guyatt G | 1999 | AIDS1999，13，： | 1 |
| 11 | A prospective study of primary cytomegalovirus infection during pregnancy: final report 显示文摘 | Griffiths PD Baboonian C | 1984 | Br J Obstet Gynaecol1984，91，4： | 1 |
| 12 | An empirical examination of Bradford's law and the scattering of scientific literature显示文摘 | Drott M C Griffith B C | 1978 | Journal of the American Society for Information Science1978，29，5： | 1 |
| 13 | Learning author-topic models from text corpora显示文摘 | Rosen-Zvi M Chemudugunta C Griffiths T | | 0，，： | 1 |
| 14 | Relationships between size, mantle area and zooxanthellae numbers in five species of giant clam Cf'ridacnidae)显示文摘 | Griffiths C L Klumpp D W | 1997 | Oceanographic Literature Review1997，44，2： | 1 |
| 15 | Investigation of microinjection moulding:Factors affecting the replication quality显示文摘 | Sha B Dimov S Griffiths C | 2007 | Journal of Materials Processing Technology2007，183，23： | 1 |
| 16 | 显示文摘 | Griffiths C H Eastwood H K | 1974 | J Appl Phys1974，45，： | 1 |
| 17 | Disturbed memory amnesia related to intensive care显示文摘 | JONES C GRIFFITHS R D HUMPHRIS G | 2000 | Memory2000，8，2： | 1 |
| 18 | Investigation of Micro--injection Moulding: Factors Affecting the Replication Quality显示文摘 | Sha B Dimov S Griffiths C | 2007 | Journal of Materials Processing Technology2007，183，23： | 1 |
| 19 | The effect of nitrate-nitrogen on bacteria and the bacterial feeding fauna in the rhizosphere of different grass species 显示文摘 | WELSCHEN R VON ARENDONK J J C M | 1992 | Oecologia1992，91，： | 1 |
| 20 | Ductility components and limits of FRP - plated RC structures 显示文摘 | D J Oehlers M C Griffith M S Mohamed All | 2009 | Construction and Building Materials2009，23，4： | 1 |
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