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| 1 | Stepwise approach and surgery for gallbladder adenomyomatosis: a mini-review显示文摘BACKGROUND: Gallbladder adenomyomatosis (GBA) is a hyperplastic disease affecting the wall of the gallbladder, with some typical features. It has historically been considered a benign condition, nevertheless recent reports highlighted a potential role of GBA in predisposing to malignancies of the gallbladder. DATA SOURCES: We reviewed the literature concerning GBA from its identification until July 2012. Owing to the relative rarity of the disease, studies often are case reports or case series. Thus we herein report a summary of the key-points concerning diagnosis and treatment of GBA, easily applicable in everyday practice, rather than a systematic review. Also, results are integrated with our recent experience. RESULTS: In our experience, we observed a trend toward an increase of GBA during the last years, probably due to enhanced ultrasonographic technical advancements and physician's expertise. GBA has distinctive imaging features. Several recent reports highlight the potential risk of cancer associated with GBA; however the disease is still classified as a benign condition. Although its correlation with malignancy has not been demonstrated, it is prudent to recommend cholecystectomy in some cases. However, in selected asymptomatic patients, a wait-and-see policy is a viable alternative. We propose an algorithm, based on GBA pathological pattern (diffuse, segmental, localized or fundal), suitable for decision-making.CONCLUSIONS: In symptomatic patients and if the diagnosis is doubtful, cholecystectomy is mandatory. Postponing surgery is an option to be offered to asymptomatic patients with low-risk GBA pattern who adhere to scheduled follow-ups. | Gianluca Pellino Guido Sciaudone Giuseppe Candilio Giuseppe Perna Antonio Santoriello Silvestro Canonico Francesco SelvaggiAuthor | 2013 | Hepatobiliary & Pancreatic Diseases International2013，12，2： | 9 |
| 2 | Two-stage surgical treatment for septic non-union of the forearm显示文摘AIM To investigate the effectiveness of a two-stage surgical procedure for the treatment of septic forearm non-union.METHODS Septic non-unions are rare complications of forearm fractures. When they occur, they modify the relationship between forearm bones leading to a severe functional impairment. Treatment is challenging and surgery and antibiotic therapy are required to achieve infection resolution. It is even harder to obtain non-union healing with good functional results. The aim of this study is to present a two stages surgical treatment for septic forearm non-union with revision and temporary stabilization of the non-union until infection has cleared and subsequently perform a new synthesis with plate, opposite bone graft strut and intercalary graft. We retrospectively reviewed 18 patients with a mean age at the time of primary injury of 34.5 years(19-57 years) and a mean follow-up of 6 years(2-10 years). All patients presented an atrophic nonunion with a mean length of the bone defect of 1.8 cm(1.2-4 cm). Complications and clinical results after surgical treatment were recorded. RESULTS Mean time to resolution of the infectious process was 8.2 wk(range 4-20 wk) after the first surgery and specific antibiotic therapy. All the non-union healed with an average time of 5 mo(range 2-10 mo) after the second step surgery. Cultures on intraoperative samples werepositive in all cases. No major intraoperative complications occurred. Two patients developed minor complications and one needed a second surgical debridement for infection resolution. At the last follow-up functional results were excellent in 5(27.8%) patients, satisfactory in 10(55.5%) and unsatisfactory in 3(16.7%) patients. No activities of daily living(ADLs) limitations were reported by 12(66.6%) patients, slight by 3(16.6%) and severe limitation by 3(16.6%) patients. Mean visual analog scale at the last follow-up was 1(0-3).CONCLUSION The two-step technique has proven to be effective to achieve resolution of the infectious process and union with good functional results and low rate of complications. | Fabrizio Perna Federico Pilla Matteo Nanni Lisa Berti Giada Lullini Francesco Traina Cesare Faldini | 2017 | World Journal of Orthopedics2017，8，6： | 2 |
| 3 | Static and rotational intensity modulated techniques for head-neck cancer radiotherapy: A planning comparison显示文摘 | Sara Broggi Lucia Perna Francesco Bonsignore Giuseppe Rinaldin Claudio Fiorino Anna Chiara Cristina Frigerio Ivana Butti Giulia Sangalli Italo Dell’Oca Nadia Di Muzio Giovanni Mauro Cattaneo Fausto Declich | 2014 | Physica Medica2014，，： | 1 |
| 4 | A case of intermittent lumbar pain radiating to the right shoulder in a 76-year-old woman (2009: 6b)显示文摘 | Luciano Cardinale Francesco Ardissone Ubaldo Familiari Mariaelena Perna Cesare Fava | 2009 | European Radiology2009，，9： | 1 |
| 5 | Phenotypie and genotypie Helicobacter pylori clarithromycin resistance and therapeutic outcome: benefits and limits 显示文摘 | De Francesco V Zullo A lerardi E Giorgio F Perna F Hassan C Morini S Panella C Vaira D | 2010 | Journal of antimicrobial chemotherapy2010，65，2： | 1 |
| 6 | A Closer Look at Incidental Findings on Cardiac Computed Tomography显示文摘 | Stefano Bartoletti Francesco Perna Pasquale Santangeli Michela Casella | 2010 | Journal of the American College of Cardiology2010，，： | 1 |
| 7 | Genetic Heterogeneity in Italian Families with IgA Nephropathy: Suggestive Linkage for Two Novel IgA Nephropathy Loci显示文摘 | Luigi Bisceglia Giuseppina Cerullo Paola Forabosco Diletta Domenica Torres Francesco Scolari Michele Di Perna Marina Foramitti Antonio Amoroso Sara Bertok Jürgen Floege Peter Rene Mertens Klaus Zerres Efstathios Alexopoulos Dimitrios Kirmizis Mazzucco Erm | 2006 | The American Journal of Human Genetics2006，，6： | 1 |
| 8 | p66Shc protein, oxidative stress, and cardiovascular complications of diabetes: the missing link显示文摘 | Pietro Francia Francesco Cosentino Marzia Schiavoni Yale Huang Enrico Perna Giovani G. Camici Thomas F. Lüscher Massimo Volpe | 2009 | Journal of Molecular Medicine2009，，9： | 1 |
| 9 | Collateral findings during computed tomography scan for atrial fibrillation ablation:Let's take a look around显示文摘The growing number of atrial fibrillation catheter ablation procedures warranted the development of advanced cardiac mapping techniques, such as image integration between electroanatomical map and cardiac computed tomography. While scanning the chest before catheter ablation, it is frequent to detect cardiac and extracardiac collateral findings. Most collateral findings are promptly recognized as benign and do not require further attention. However, sometimes clinically relevant collateral findings are detected, which often warrant extra diagnostic examinations or even invasive procedure, and sometimes need to be followed-up over time. Even though reporting and further investigating collateral findings has not shown a clear survival benefit, almost all the working groups providing data on collateral findings reported some collateral findings eventually coming out to be malignancies, sometimes at an early stage. Therefore, there is currently no clear agreement about the right strategy to be followed. | Francesco Perna Michela Casella Maria Lucia Narducci Antonio Dello Russo Gianluigi Bencardino Gianluca Pontone Gemma Pelargonio Daniele Andreini Nicola Vitulano Francesca Pizzamiglio Edoardo Conte Filippo Crea Claudio Tondo | 2016 | World Journal of Cardiology2016，8，4： | 0 |
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