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| 1 | Electrical storm: A clinical and electrophysiological overview显示文摘Electrical storm(ES) is a clinical condition characterized by three or more ventricular arrhythmia episodes leading to appropriate implantable cardioverterdefibrillator(ICD) therapies in a 24 h period. Mostly, arrhythmias responsible of ES are multiple morphologies of monomorphic ventricular tachycardia(VT), but polymorphic VT and ventricular fibrillation can also result in ES. Clinical presentation is very dramatic in most cases, strictly related to the cardiac disease that may worsen electrical and hemodynamic decompensation. Therefore ES management is challenging in the majority of cases and a high mortality is the rule both in the acute and in the long-term phases. Different underlying cardiomyopathies provide significant clues into the mechanism of ES, which can arise in the setting of structural arrhythmogenic cardiomyopathies or rarely in patients with inherited arrhythmic syndrome, impacting on pharmacological treatment, on ICD programming, and on the opportunity to apply strategies of catheter ablation. This latter has become a pivotal form of treatment due to its high efficacy in modifying the arrhythmogenic substrate and in achieving rhythm stability, aiming at reducing recurrences of ventricular arrhythmia and at improving overall survival. In this review, the most relevant epidemiological and clinical aspects of ES, with regard to the acute and long-term follow-up implications, were evaluated, focusing on these novel therapeutic strategies of treatment. | Sergio Conti Salvatore Pala Viviana Biagioli Giuseppe Del Giorno Martina Zucchetti Eleonora Russo Vittoria Marino Antonio Dello Russo Michela Casella Francesca Pizzamiglio Valentina Catto Claudio Tondo Corrado Carbucicchio | 2015 | World Journal of Cardiology2015,7,9: | 9 |
| 2 | Neurological disorders and inflammatory bowel diseases显示文摘Extraintestinal manifestations occur in about one-third of patients living with inflammatory bowel disease(IBD) and may precede the onset of gastrointestinal symptoms by many years. Neurologic disorders associated with IBD are not frequent, being reported in 3% of patients, but they often represent an important cause of morbidity and a relevant diagnostic issue. In addition, the increasing use of immunosuppressant and biological therapies for IBD may also play a pivotal role in the development of neurological disorders of different type and pathogenesis. Hence, we provide a complete and profound review of the main features of neurological complications associated with IBD, with particular reference to those related to drugs and with a specific focus on their clinical presentation and possible pathophysiological mechanisms. | Giovanni Casella Gian Eugenio Tontini Gabrio Bassotti Luca Pastorelli Vincenzo Villanacci Luisa Spina Vittorio Baldini Maurizio Vecchi | 2014 | World Journal of Gastroenterology2014,20,27: | 7 |
| 3 | Effectiveness of an intervention for reducing social stigma towards mental illness in adolescents显示文摘AIM: To evaluate the effectiveness of an intervention for reducing social stigma towards mental illness in adolescents. The effect of gender and knowledge of someone with mental illness was measured. METHODS: Two hundred and eighty secondary school students were evaluated using the Community Attitudes towards Mental Illness(CAMI) questionnaire. The schools were randomized and some received the intervention and others acted as the control group. The programme consisted of providing information via a documentary film and of contact with healthcare staff in order to reduce the social stigma within the school environment. RESULTS: The intervention was effective in reducing the CAMI authoritarianism and social restrictiveness subscales. The intervention showed significant changes in girls in terms of authoritarianism and social restrictiveness, while boys only showed significant changes in authoritarianism. Following the intervention, a significant reduction was found in authoritarianism and social restrictiveness in those who knew someone with mental illness, and only in authoritarianism in those who did not know anyone with mental illness. CONCLUSION: The intervention was effective to reduce social stigma towards people with mental illness, especially in the area of authoritarianism. Some differences were found depending on gender and whether or not the subjects knew someone with mental illness. | Regina Vila-Badia Francisco Martínez-Zambrano Otilia Arenas Emma Casas-Anguera Esther García-Morales Raúl Villellas José Ramón Martín María Belén Pérez-Franco Tamara Valduciel Diana Casellas Mar García-Franco Jose Miguel Joaquim Balsera Gemma Pascual Eugènia Julia Susana Ochoa | 2016 | World Journal of Psychiatry2016,6,2: | 4 |
| 4 | Gastric metastasis by lung small cell carcinoma显示文摘胃肠道的转移瘤是稀罕的。我们由于主要的肺癌症描述胃的转移的一个案例,由上面的胃肠的内视镜检查法(UGIE ) 揭示了。到胃的造血的转移是一个稀罕事件。到我们的知识,仅仅 55 个案例在国际文学被描述了。在这些病人,预后是很差的。我们此处由肺报导胃的转移的一个案例小房间癌,与关于这个稀罕实体的文学的评论。 | Giovanni Casella Camillo Di Bella Antonino Roberto Cambareri Carmelo Antonio Buda Gianluigi Corti Filippo Magri Stefano Crippa Vittorio Baldini | 2006 | World Journal of Gastroenterology2006,12,25: | 3 |
| 5 | Evaluation of 5 versus 10 granulocyteaphaeresis sessions in steroid-dependent ulcerative colitis: A pilot, prospective, multicenter, randomized study显示文摘瞄准:与活跃类固醇依赖者 ulcerative 在病人与 10 个 granulocyteaphaeresis 会议相比评估 5 的功效。方法:在这名飞行员,未来,多集中使随机化的试用,有中等活跃的类固醇的 20 个病人 -- 依赖 ulcerative 被使随机化到 5 或 10 个 granulocyteaphaeresis 会议。主要目的是在 wk 的临床的宽恕 17。第二等的措施包括了内视镜的宽恕和类固醇消费。结果:九个病人被使随机化到 5 个 granulocyteaphaeresis 会议(组 1 ) 和 11 个病人到 10 个 granulocyteaphaeresis 会议(组 2 ) 。在 wk 17,在在组 2 的组 1 病人和 45.45% 的 37.5% 病人在临床的宽恕。临床的宽恕被内视镜的宽恕在所有情况中伴随。完成宽恕的百分之 86 个病人在 wk 是没有类固醇的 17。每日的类固醇要求在组 2 是显著地更低的。病人的 89% 在一年后续期间留在宽恕。一个严肃的不利事件不与学习治疗有关,被报导。结论:Granulocyteaphaeresis 为类固醇依赖者 ulcerative 的治疗安全、有效。在这张人口,增加 aphaeresis 会议的数字没与更高的宽恕率被联系,但是负担得起重要类固醇圆材效果。 | Elena Ricart Maria Esteve Montserrat Andreu Francesc Casellas David Monfort Miquel Sans Natalia Oudovenko Raúl Lafuente Julián Panés | 2007 | World Journal of Gastroenterology2007,13,15: | 3 |
| 6 | Colonisation by F aecalibacterium prausnitzii and maintenance of clinical remission in patients with ulcerative colitis显示文摘 | E. Varela C. Manichanh M. Gallart A. Torrejón N. Borruel F. Casellas F. Guarner M. Antolin | 2013 | Aliment Pharmacol Ther2013,,2: | 3 |
| 7 | Effect of heavy metals and water content on the strength of magnesium phosphate cements显示文摘 | Irene Buj Josep Torras Daniel Casellas Miquel Rovira Joan de Pablo | 2009 | Journal of Hazardous Materials2009,,1: | 2 |
| 8 | Histological healing in inflammatory bowel disease:A still unfulfilled promise显示文摘Treatment of inflammatory bowel disease(IBD) is traditionally based on several drugs,including salicylates,corticosteroids,and antibiotics;in addition,the therapeutic armamentarium has considerably evolved with the advent of newer,effective therapeutic measures(such as the biological agents) that are able to improve in a considerable manner both the clinical and endoscopic variables.Thus,mucosal healing,at least considered from an endoscopic point of view,is today regarded as the ultimate endpoint for treatment of these conditions.However,it is also increasingly clear that endoscopic healing is not necessarily paralleled by histological healing;There are few doubts that the latter should be considered as a true,objective healing and the ultimate goal to reach when treating patients with IBD.Unfortunately,and surprisingly,only a few,incomplete,and somewhat conflicting data exist on this topic,especially because there is still the need to standardize both histological assessment and the severity grading of these disorders;Issues that have not been yet been resolved for clinical practice and therapeutic trials.Hopefully,with the help of an increased awareness on the clinical researchers' side,and the availability of dedicated pathologists on the other side,this matter will be effectively faced and resolved in the near future. | Vincenzo Villanacci Elisabetta Antonelli Karel Geboes Giovanni Casella Gabrio Bassotti | 2013 | World Journal of Gastroenterology2013,19,7: | 2 |
| 9 | Antithrombin III (ATILL) replacement therapy in patients with sepsis and/or postsurgical complications: a controlled double-blind, randomized, multicenter study显示文摘 | F. Baudo T. M. Caimi F. deCataldo A. Ravizza S. Arlati G. Casella D. Carugo G. Palareti C. Legnani L. Ridolfi R. Rossi A. D’Angelo L. Crippa D. Giudici G. Gallioli A. Wolfler G. Calori | 1998 | Intensive Care Medicine1998,,4: | 2 |
| 10 | Factors that impact health-related quality of life in adults with celiac disease:A multicenter study显示文摘AIM: To evaluate the factors involved in the impairment of health-related quality of life (HRQOL) in patients with celiac disease.METHODS: A multicenter, cross-sectional prospective study was performed in patients with celiac disease who completed two HRQOL questionnaires: the gastrointestinal quality of life index (GIQLI) and the EuroQol-5D (EQ).RESULTS: Three hundred and forty patients (163 controlled with a gluten-free diet, and 177 newly diagnosed with a normal diet) were included. The GIQLI score was significantly better in patients on a gluten-free diet (GFD) than in non-treated patients on their usual diet, both in terms of the overall score (3.3 vs 2.7, respectively; P < 0.001), as well as on the individual questionnaire dimensions. Both the preference value of the EQ as the visual analogue scale were significantly better in treated than in non-treated patients (0.93 vs 0.72 P < 0.001 and 80 vs 70 P < 0.001, respectively). Variables significantly associated with a worse HRQOL score were female gender, failure to adhere to a GFD, and symptomatic status.CONCLUSION: In untreated celiac disease, the most important factors that influence patient perception of health are the presence of symptoms and a normal diet. HRQOL improves to levels similar to those described in the general population in celiac disease patients well controlled with a GFD. | F Casellas L Rodrigo J López Vivancos S Riestra C Pantiga JS Baudet F Junquera V Puig Diví C Abadia M Papo J Gelabert JR Malagelada | 2008 | World Journal of Gastroenterology2008,14,1: | 2 |
| 11 | Survey of human genes of retroviral origin: identification and transcriptome of the genes with coding capacity for complete envelope proteins 显示文摘 | de Parseval N Lazar V Casella JF | 2003 | J Virol2003,77,10: | 1 |
| 12 | Improved set estimators for a multivariate normal mean显示文摘 | Casella G | 1984 | Statistics & Decisions Supplement Issue1984,,1: | 1 |
| 13 | Urine detection of survivin is a sensitive marker for the noninvasive diagnosis of bladder cancer显示文摘 | Shariat SF Casella R Khoddami SM | 2004 | J Urol2004,17,21: | 1 |
| 14 | Berger, statistical inference显示文摘 | Casella G Roger L | 2008 | California: Brooks/Cole2008,,: | 1 |
| 15 | Explaining the Gibbs sampler显示文摘 | Casella G George E | 1992 | TheAmerican Statistician1992,46,3: | 1 |
| 16 | Comparison of common carotid artery intima-media thickness between Brazilian Euro-descendants and Afro-descendants with atherosclerosis risk factors 显示文摘 | Casella IB Sotelo FJ Yamazaki Y | 2009 | Clinics2009,64,7: | 1 |
| 17 | Selective activation of the p38MAPK pathway by synthetic monophosphoryl lipid A 显示文摘 | Cekie C Casella CR Eaves CA | 2009 | J Biol Chem2009,284,31: | 1 |
| 18 | Do procalcitonin algorithms modify mortality显示文摘 | Ferrari L Casella F Podda GM | | 0,,02: | 1 |
| 19 | Effect of the cutting process on the fatigue behavior of press hardened and high strength dual phase steels 显示文摘 | Lara A Picas I Casellas D | 2013 | Journal of Materials Processing Technology2013,213,11: | 1 |
| 20 | Effects of thermal hydrolysis on activated sludge solubilization显示文摘 | Laurent J Casellas M Carrere H | 2010 | Surface Properties and Heavy Metals Biosorption2010,166,3: | 1 |