|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Nuclear imaging in detection and monitoring of cardiotoxicity显示文摘Cardiotoxicity as a result of cancer treatment is a novel and serious public health issue that has a significant impact on a cancer patient’s management and outcome.The coexistence of cancer and cardiac disease in the same patient is more common because of aging population and improvements in the efficacy of antitumor agents.Left ventricular dysfunction is the most typical manifestation and can lead to heart failure.Left ventricular ejection fraction measurement by echocardiography and multigated radionuclide angiography is the most common diagnostic approach to detect cardiac damage,but it identifies a late manifestation of myocardial injury.Early non-invasive imaging techniques are needed for the diagnosis and monitoringof cardiotoxic effects.Although echocardiography and cardiac magnetic resonance are the most commonly used imaging techniques for cardiotoxicity assessment,greater attention is focused on new nuclear cardiologic techniques,which can identify high-risk patients in the early stage and visualize the pathophysiologic process at the tissue level before clinical manifestation.The aim of this review is to summarize the role of nuclear imaging techniques in the non-invasive detection of myocardial damage related to antineoplastic therapy at the reversible stage,focusing on the current role and future perspectives of nuclear imaging techniques and molecular radiotracers in detection and monitoring of cardiotoxicity. | Carmen D’Amore Paola Gargiulo Stefania Paolillo Angela Maria Pellegrino Tiziana Formisano Antonio Mariniello Giuseppe DellaRatta Elisabetta Iardino Marianna D’Amato Lucia La Mura Irma Fabiani Flavia Fusco Pasquale Perrone Filardi | 2014 | World Journal of Radiology2014，6，7： | 2 |
| 2 | Functional connectivity as revealed by spatial independent component analysis of fMRI measurements during rest显示文摘 | van de VEN V G FORMISANO E PRVULOVIC D | 2004 | Hum Brain Map2004，22，3： | 1 |
| 3 | Gastric cancer: surgical treatment and prognostic score显示文摘 | Guida F Formisano G Esposito D | 2008 | Minerva Chit2008，63，2： | 1 |
| 4 | Product and production process modeling and configuration显示文摘 | CAMPAGNA D FORMISANO A | 2013 | Fundamenta Inforrna- ticae2013，124，4： | 1 |
| 5 | The functional neuroanatomy of target detection:an fMRI study of visual and auditory oddball tasks显示文摘 | Linden DEJ Prvulovic D Formisano E | | 0，，08： | 1 |
| 6 | SNP genotyping in melons: genetic variation, population structure, and linkage disequilibrium显示文摘 | Cristina Esteras Gelsomina Formisano Cristina Roig Aurora Díaz José Blanca Jordi Garcia-Mas María Luisa Gómez-Guillamón Ana Isabel López-Sesé Almudena Lázaro Antonio J. Monforte Belén Picó | 2013 | Theoretical and Applied Genetics2013，，5： | 1 |
| 7 | Bisphenol A in polycystic ovary syndrome and its association with liver–spleen axis显示文摘 | Giovanni Tarantino Rossella Valentino Carolina Di Somma Vittoria D’Esposito Federica Passaretti Genoveffa Pizza Valentina Brancato Francesco Orio Pietro Formisano Annamaria Colao Silvia Savastano | 2013 | Clin Endocrinol2013，，3： | 1 |
| 8 | Reticulocyte count and reticulocyte maturation profile in human umbilical cord blood from healthy newborns显示文摘 | Maconi M Formisano D Cavalca L | 2010 | Lab Hematol2010，16，： | 1 |
| 9 | PPARG in Human Adipogenesis: Differential Contribution of Canonical Transcripts and Dominant Negative Isoforms显示文摘 | M. Aprile M. R. Ambrosio V. D’Esposito F. Beguinot P. Formisano V. Costa A. Ciccodicola Guangrui Yang | 2014 | PPAR Research2014，，： | 1 |
| 10 | Gastric cancer : surgical treat-ment and prognostic score 显示文摘 | Guida F Formisano G Esposito D | 2008 | Minerva Chir2008，63，2： | 1 |
| 11 | Functional locked-in syndrome as recovery phase of vegetative state显示文摘 | Formisano R D 'ippolito M Catani S | 2013 | Brain Injury2013，27，11： | 1 |
| 12 | Functional Connectivity as Revealed by Spatial Independent Component Analysis of Fmri Measurements During Rest 显示文摘 | Van de Ven VG Formisano E Prvulovic D | 2004 | Human B rain Mapping2004，22，3： | 1 |
| 13 | The experimental combination of rTMS and fMRI reveals the functional relevance of parietal cortex for visuospatial functions显示文摘 | A.T Sack D Hubl D Prvulovic E Formisano M Jandl F.E Zanella K Maurer R Goebel T Dierks D.E.J Linden | 2002 | Cognitive Brain Research2002，，1： | 1 |
| 14 | Functional connectivity as revealed by spatial independent component analysis of fMRI measurements during rest 显示文摘 | Van de Yen VG Formisano E Prvulovic D | 2004 | Human Brain Mapping2004，22，3： | 1 |
| 15 | Percutaneous laser ablation of cold benign thyroid nodules: a 3 year follow-up study in 122 patients 显示文摘 | Valcavi R Riganti F Bertani A Formisano D Pacella C M | 2010 | Thyroid2010，20，： | 1 |
| 16 | Functional connectivity as revealed by spatial independent component anal- ysis of fMRI measurements during rest 显示文摘 | van de Ven VG Formisano E Prvulovic D | 2004 | Hum Brain Mapp2004，22，3： | 1 |
| 17 | Usefulness of delayed enhancement by magnetic resonance imaging in hypertrophic cardiomyopathy as a marker of disease and its severity显示文摘 | Aquaro G D Masci P Formisano F | 2010 | AmJ Cardiol2010，105，3： | 1 |
| 18 | The Trichoderma-plant interaction is mediated by avirulence proteins produced by this fungus显示文摘The molecular basis of Trichoderma -plant interaction is very complex and still not completely understood. The colonization of the root system by rhizosphere competent strains of Trichoderma results in increased development of root/aerial systems, in improved yields and in plant disease control. Other beneficial effects, such as the induction of plant systemic resistance, have also been described. To understand the mechanisms involved we are using different approaches, including the making of transformants expressing genes that encode for compounds able to affect plant response to pathogens. Trichoderma transformants carrying the avirulence gene Avr4 from Cladosporium fulvum under the control of constitutive and inducible promoters were obtained and tested on tomato plants having the Cf4 resistance gene. Necrosis and suberification zones, similar to the symptoms appearing during Cladosporium-tomato interaction, were found when the roots of the Cf4 plants were treated with Avr4-Trichoderma. This demonstrates that selected Trichoderma strains are able to transfer to the plant molecules that may deeply affect metabolism, disease resistance etc. Therefore, these beneficial fungi can be regarded as biotechnological tools to provide a variety of crops with useful compounds. Moreover, in in vitro competition assays the transformants were found to be more effective as antagonists against Alternaria alternata than the wild type. Trichoderma sends a variety of biochemical signals to the plants including avirulence molecules; therefore the presence of avr-like proteins in the fungus proteome was investigated. Proteome analysis has permitted us to isolate and sequence many proteins potentially having this function. From the extracellular protein extracts, we have purified and sequenced a protein with structural characteristics similar to Avr4 of C. fulvum. The protein, Hytra1, was found to be a hydrophobin with chitin binding activity, the typical 8 cysteine residues, and 4 disulfide bridges. Infiltrations of the extracellular protein fractions containing Hytra1 resulted in a strong HR reaction on tobacco and tomato leaves, and induction of a novel phytoalexin. | Ruocco M Lanzuise S Woo S L Ambrosino P Marra R Turrà D Gigante S Formisano E Scala F Kip N P J G M de Wit Lorito M | 2004 | 浙江大学学报(农业与生命科学版)2004，30，4： | 1 |
| 19 | Analysis of essential oil from Teucrium maghrebinum Greuter et Burdet growing wild in Algeria显示文摘 | Formisano C Rigano D Senatore F | 2009 | Nat Prod Commun2009，4，3： | 1 |
| 20 | The functional neuroanatomy of target detection:An fMRI study of visual and auditory oddball tasks显示文摘 | Linden DEJ Prvulovic D Formisano E | | 0，，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员