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| 1 | Oropharyngeal acid reflux and motility abnormalities of the proximal esophagus显示文摘AIM To investigate the relationship between pathological oropharyngeal(OP) acid exposure and esophageal motility in patients with extra-esophageal syndromes.METHODS In this prospective study we enrolled consecutive outpatients with extra-esophageal symptoms suspected to be related to gastroesophageal reflux disease(GERD). We enrolled only patients with a reflux symptom index(RSI) score-higher than 13 and with previous lung, allergy and ear, nose and throat evaluations excluding other specific diagnoses. All patients underwent 24-h OP pH-metry with the Dx probe and esophageal highresolution manometry(HRM). Patients were divided into two groups on the basis of a normal or pathological p H-metric finding(Ryan Score) and all manometric characteristics of the two groups were compared.RESULTS We examined 135 patients with chronic extra-esophageal syndromes. Fifty-one were considered eligible for the study. Of these, 42 decided to participate in the protocol. Patients were divided into two groups on the basis of normal or pathological OP acid exposure. All the HRM parameters were compared for the two groups. Significant differences were found in the median upper esophageal sphincter resting pressure(median 71 mmH g vs 126 mmH g, P = 0.004) and the median proximal contractile integral(median 215.5 cm·mmH g·s vs 313.5 cm·mmH g·s, P = 0.039), both being lower in the group with pathological OP acid exposure, and the number of contractions with small or large breaks, which were more frequent in the same group. This group also had a larger number of peristaltic contractions with breaks in the 20 mm Hg isobaric contour(38.7% vs 15.38%, P < 0.0001).CONCLUSION In patients with suspected GERD-related extraesophageal syndromes pathological OP acid exposure was associated with weaker proximal esophageal motility. | Sandro Passaretti Giorgia Mazzoleni Cristian Vailati Pier Alberto Testoni | 2016 | World Journal of Gastroenterology2016，22，40： | 5 |
| 2 | Clinical and molecular spectrum of Wiedemann-Steiner syndrome, an emerging member of the chromatinopathy family显示文摘Wiedemann-Steiner syndrome(OMIM#605130)is a rare congenital malformation syndrome characterized by hypertrichosis cubiti associated with short stature;consistent facial features,including long eyelashes,thick or arched eyebrows with a lateral flare,wide nasal bridge,and downslanting and vertically narrow palpebral fissures;mild to moderate intellectual disability;behavioral difficulties;and hypertrichosis on the back.It is caused by heterozygous pathogenic variants in KMT2A.This gene has an established role in histone methylation,which explains the overlap of Wiedemann-Steiner syndrome with other chromatinopathies,a heterogeneous group of syndromic conditions that share a common trigger:The disruption of one of the genes involved in chromatin modification,leading to dysfunction of the epigenetic machinery. | Paolo Fontana Francesco Fioravanti Passaretti Marianna Maioli Giuseppina Cantalupo Francesca Scarano Fortunato Lonardo | 2020 | World Journal of Medical Genetics2020，9，1： | 2 |
| 3 | Rectal Distensibility and Symptoms After Stapled and Milligan–Morgan Operation for Hemorrhoids显示文摘 | Maura Corsetti Paola Nardi Salvatore Pietro Sandro Passaretti Pier Alberto Testoni Carlo Staudacher | 2009 | Journal of Gastrointestinal Surgery2009，，12： | 1 |
| 4 | Injectable tissue-engineered cartilage using a bibrin glue polymer显示文摘 | Passaretti D Huang W | 1999 | Plast Reconstr Surg1999，103，7： | 1 |
| 5 | Injectable tissue-engineered cartilage using a fibrin glue polymer显示文摘 | Silverman RP Passaretti D Huang W | 1999 | Plast Reconstr Surg1999，103，7： | 1 |
| 6 | Injectable tissue- engineered cartilage using a fibrin glue polymer 显示文摘 | Silverman RP Passaretti D Huang W | 1999 | Plast Reeonstr Surg1999，103，7： | 1 |
| 7 | Cultured chondrocytes produce injectable tissue-engineered cartilage in hydrogel polymer显示文摘 | Passaretti D Silverman R P Huang W | 2001 | Tissue Eng2001，7，6： | 1 |
| 8 | Public reporting of health care-associated infections(HAIs):approach to choosing HAI measures显示文摘 | Passaretti CL Barclay P Pronovost P | 2011 | Infect Control Hosp Epidemiol2011，32，8： | 1 |
| 9 | The impact of sex, gender and pregnancy on 2009 H1 N1 disease 显示文摘 | KLEIN S L PASSARETTI C ANKER M | 2010 | Biol Sex Differ2010，4，1： | 1 |
| 10 | Application of high-opacity precipitated calcium carbonare显示文摘 | Juno D Passaretti Trudy D Young Michael J Herman | 1995 | Tappi Journal1995，，12： | 1 |
| 11 | Bisphenol-A im- pairs insulinaction and up-regulates inflammatory pathways in hu- man subcutaneous adipocytes and 3T3-L1 cells 显示文摘 | Valentino R D' Esposito V Passaretti F | 2013 | PLoS One2013，8，82： | 1 |
| 12 | Application of high-opacity precipitated calcium carbonate显示文摘 | Passaretti J D Young T D Herman M J | | 0，，： | 1 |
| 13 | A real-time multiplexed PCR assay for rapid detection and differentiation of Campylobacter jejuni and Campylobacter coli 显示文摘 | LAGIER M J JOSEPH L A PASSARETTI T V | 2004 | Molecular and Cellular Probes2004，18，4： | 1 |
| 14 | Adi- pocyte-released Insulin-like Growth Factor-1 is Regulated by Glu- cose and Fatty Acids and Controls Breast?Cancer Cell Growth in Vitro 显示文摘 | D'ESPOSITO V PASSARETTI F HAMMARSTEDT A | 2012 | Diabetologia2012，，10： | 1 |
| 15 | Bisphenol A in polycystic ovary syndrome and its association with liver–spleen axis显示文摘 | Giovanni Tarantino Rossella Valentino Carolina Di Somma Vittoria D’Esposito Federica Passaretti Genoveffa Pizza Valentina Brancato Francesco Orio Pietro Formisano Annamaria Colao Silvia Savastano | 2013 | Clin Endocrinol2013，，3： | 1 |
| 16 | Low-temperature synthesis and properties of cobalt sulfide (Co9S8),nickel sulfide (Ni3S2),and iron sulfide (Fe7S8)显示文摘 | Kershaw R Passaretti J D | 1984 | J Inorg Chem1984，23，： | 1 |
| 17 | Public reporting of health care-associated infections(HCAIs):approach to choosing HAI measures显示文摘 | Passaretti CL Barclay P Pronovost P | 2011 | Infect Control Hosp Epidemiol2011，32，8： | 1 |
| 18 | Chlorhexidine: expanding the armamentarium for infection control and prevention显示文摘 | Milstone AM Passaretti CL Perl TM | 2008 | Clin Infect Dis2008，46，2： | 1 |
| 19 | Injectable tissue-engineered cartilage using a fibrin glue polymer显示文摘 | Silverman RP David Passaretti Wynne Huang | 1999 | Plastic and reconstructive surgery1999，103，： | 1 |
| 20 | Anorectal mano- metry with water-perfused catheter in healthy adults with no functional bowel disorders 显示文摘 | Corsetti M Passaretti S Barzaghi F | 2010 | Colorectal Dis2010，12，： | 1 |
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