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| 1 | Spermiogram and sperm head morphometry assessed by multivariate cluster analysis results during adolescence (12-18 years) and the effect of varicocele显示文摘这个工作从精索静脉曲张的 12 ~ 18 岁,和效果在青少年评估精子头 morphometric 特征。在年龄的 150 和 224 个月之间的志愿者(平均数 191, n = 87 ) ,在 12 岁到达了 oigarche,在 Barranquilla 的区域被招募,哥伦比亚。精子头的 Morphometric 分析与主要部件(PC ) 和判别式分析被执行。联合精液和精子参数提供了五 PC:二与精子 morphometry 有关,到精子活动性,并且二到精液部件。精索静脉曲张和 nonvaricocele 组的 morphometric 结果上的判别式分析没提供一个有用分类矩阵。精液相关的 PC,最解释(40%) 与精子活动性有关。包括精子头延伸和尺寸,二 PC 是足够的评估精子 morphometric 特征。大多数 morphometric 变量与年龄被相关,随尺寸的增加和在精子头的延伸的减少。为头尺寸,全部精子人口能被划分成二 morphometric subpopulations, SP1 和 SP2,它没在青春期期间变化。为精索静脉曲张个人,一般来说,更大的有的 SP1 和更多的伸长的精子比 SP2 出发,它有更小并且更多的伸长的头比在 nonvaricocele 人。在摘要, CASA-Morph 和 multivariate 簇分析估计的精子头 morphometry 提供精液结构并且可能的更好的理解精子功能。Morphometric 分析比从常规精液分析获得的数据提供更多信息。 | Fernando Vasquez Caries Soler Patricia Camps Anthony Valverde Almudena Garcia-Molina | 2016 | Asian Journal of Andrology2016，18，6： | 5 |
| 2 | Efficiency of white lupin in the removal of mercury from contaminated soils: Soil and hydroponic experiments显示文摘This study examined the ability of the white lupin to remove mercury (Hg) from a hydroponic system (Hg concentrations 0, 1.25, 2.5, 5 and 10 μmol/L) and from soil in pots and lysimeters (total Hg concentration (19.2 ± 1.9) mg/kg availability 0.07%, and (28.9 ± 0.4) mg/kg availability 0.09%, respectively), and investigated the accumulation and distribution of Hg in different parts of the plant. White lupin roots efficiently took up Hg, but its translocation to the harvestable parts of the plant was low. The Hg concentration in the seeds posed no risk to human health according to the recommendations of the World Health Organization, but the shoots should not be used as fodder for livestock, at least when unmixed with other fodder crops. The accumulation of Hg in the hydroponically-grown plants was linear over the concentration range tested. The amount of Hg retained in the roots, relative to the shoots, was almost constant irrespective of Hg dose (90%). In the soil experiments, Hg accumulation increased with exposure time and was the greater in the lysimeter than in the pot experiments. Although Hg removal was the greater in the hydroponic system, revealing the potential of the white lupin to extract Hg, bioaccumulation was the greatest in the lysimeter-grown plants; the latter system more likely reflects the true behaviour of white lupin in the field when Hg availability is a factor that limits Hg removal. The present results suggest that the white lupin could be used in long-term soil reclamation strategies that include the goal of profitable land use in Hg-polluted areas. | Pilar Zornoza Rocío Milln M. Jos Sierra Almudena Seco Elvira Esteban | 2010 | Journal of Environmental Sciences2010，22，3： | 4 |
| 3 | Physical activation of graphene: An effective, simple and clean procedure for obtaining microporous graphene for high-performance Li/S batteries显示文摘Graphe ne nano sheets are a promising scaffold to accommodate S for achievi ng high performa nee Li/S battery. Nano sheet activation is used as a viable strategy to induce a micropore system and further improve the battery performance. Accordingly, chemical activation methods dominate despite the need of multiple stages, which slow down the process in addition to making them tiresome. Here, a three-dimensional (3D) N-doped graphene specimen was physically activated with CO2, a clean and single step process, and used for the preparation of a sulfur composite (A-3DNG/S). The A-3DNG/S composite exhibited outstanding electrochemical properties such as an excellent rate capability (1,000 mAh·g^-1 at 2C), high reversible capacity and cycling stability (average capacity ~ 800 mAh·g^-1 at 1C after 200 cycles), values which exceed those measured in chemically activated graphene. Therefore, these results support the use of physical activation as a simple and efficient alternative to improve the performance of carbons as an S host for high-performance Li-S batteries. | Almudena Benitez Alvaro Caballero Julian Morales Jusef Hassoun Enrique Rodriguez-Castellon Jesus Canales-Vazquez | 2019 | Nano Research2019，12，4： | 3 |
| 4 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 5 | 肝切除术后手术部位感染的预测因素:美国国家外科质量改善计划数据多中心分析显示文摘目的术后感染是肝切除术后最常见的并发症,对住院时间、并发症发生率及死亡率有显著的影响。手术部位感染(SSI)是外科病人最常见的院内感染,占到所有感染中的38%。SSI是指单独发生在切口部位皮肤、或皮下组织、或脏器部位的感染。美国国家院内感染监测系统(NNISS)发布2002-2004年期间SSI的总体发生率为2.6%,这其中2/3为切口部位感染、1/3为脏器部位感染。文献报道指出肝切除术后感染发生率为4%~20%、SSI发生率为2.1%~14.5%。本研究的目的是确定肝切除术后SSI的预测因素。方法:对2005~2007年在美国173家医院接受肝切除的患者数据进行分析,这些数据均来自于美国外科医师学院—国立外科质量改善计划数据库(ACS-NSQIP)。ACS-NSQIP收集的患者资料包括术前危险因素、术中因素、及术后30日的并发症发生率和死亡率在内的135个变量。将接受肝段切除、肝左叶切除、肝右叶切除或者肝三叶切除的患者全部纳入研究中。总计接受开腹/腹腔镜肝切除手术的患者有2332例。主要检测的结果是术后30日SSI发生率(包括浅表的、深部的或者脏器部位的SSI)。对患者住院时间和术后30日死亡率也进行分析。根据不同的肝切除手术类型,使用方差分析和卡方检验对结果进行比较分析。结果:肝段切除术的SSI为9.7%,肝左叶切除术的SSI为11.2%,肝右叶切除术的SSI为13.3%,肝三叶切除术的SSI为18.3%,SSI的总体发生率为11.5%。SSI的发生率在各种不同肝切除手术之间的差异是有统计学意义的(P<0.001)。单变量分析得出的结论包括:SSI更常见于男性、吸烟、术前有开放性伤口,低白蛋白血症、血清胆红素和碱性磷酸酶水平升高的患者;手术时间和输血与SSI发生具有相关性。与未发生SSI组(n=2064)比较,发生SSI组(n=268)的住院时间增加6.1日(13.6日vs7.5日;P<0.001)、术后30日内再手术的可能性增加12.5%(16.0%vs 3.5%;P<0.001)、死亡率增加3.1%(5.2%vs 2.1%;P=0.002)。回归模型示SSI围手术期独立的预测因子是:术前有开放性伤口/感染,血清钠>145 mmol/L,低白蛋白血症,血清总胆红素>1.0mg/dl和手术时间。而手术方式、切口等级和输血不是独立的有显著意义的术中变量。深部脏器部位SSI发生的独立预测因子除上述变量以外,还包括有透析治疗史和吸烟。卡方检验示深部脏器SSI发生率与手术时间之间具有线性关系(P<0.001)。NSQIP指出术前开放性伤口常见的三大原因是:既往手术的开放性伤口、糖尿病性溃疡、褥疮。结论本研究的结果可能有以下作用:筛选术前存在SSI风险的患者并且予以纠正,以达到降低肝切除术后SSI发生率、死亡率、住院时间和最终的治疗费用的目的。 | Almudena Moreno Elola-Olaso 吴若林 耿小平 | 2012 | 肝胆外科杂志2012，20，3： | 2 |
| 6 | GOECP/SEOR clinical guidelines on radiotherapy for malignant pleural mesothelioma显示文摘Malignant pleural mesothelioma(MPM)is a rare tumor with poor prognosis and rising incidence.Palliative care is common in MPM as radical treatment with curative intent is often not possible due to metastasis or extensive locoregional involvement.Numerous therapeutic advances have been made in recent years,including the use of less aggressive surgical techniques associated with lower morbidity and mortality(e.g.,pleurectomy/decortication),technological advancements in the field of radiotherapy(intensity-modulated radiotherapy,image-guided radiotherapy,stereotactic body radiotherapy,proton therapy),and developments in systemic therapies(chemotherapy and immunotherapy).These improvements have had as yet only a modest effect on local control and survival.Advances in the management of MPM and standardization of care are hampered by the evidence to date,limited by high heterogeneity among studies and small sample sizes.In this clinical guideline prepared by the oncological group for the study of lung cancer of the Spanish Society of Radiation Oncology,we review clinical,histologic,and therapeutic aspects of MPM,with a particular focus on all aspects relating to radiotherapy,including the current evidence base,associations with chemotherapy and surgery,treatment volumes and planning,technological advances,and reradiation. | Javier Luna Andrea Bobo Joaquín José Cabrera-Rodriguez María Pagola Margarita Martín-Martín María Ángeles González Ruiz Miguel Montijano Aurora Rodríguez Lira Pelari-Mici Almudena Corbacho Marta Moreno Felipe Couñago | 2021 | World Journal of Clinical Oncology2021，12，8： | 2 |
| 7 | Repair of Acute Myocardial Infarction With Induced Pluripotent Stem Cells Induced by Human Stemness Factors显示文摘 | Timothy J. Nelson Almudena Martinez-Fernandez Satsuki Yamada Carmen Perez-Terzic Yasuhiro Ikeda Andre Terzic | 2009 | Circulation2009，，5： | 2 |
| 8 | Double attention bias for positive and emotional faces in clinical depression:Evidence from an eye-tracking study显示文摘 | Almudena Duque Carmelo Vazquez | 2015 | Journal of Behavior Therapy and Experimental Psychiatry2015，46，： | 1 |
| 9 | Steady-state visual evoked potentials can be explained by temporal superposition of transient event-related responses显示文摘 | ALMUDENA C PAULA P A CAMPO P | 2011 | Plos One2011，6，14： | 1 |
| 10 | Predictors of weight gain in a Mediterranean cohort : The seguimiento Universidad de Navarra study显示文摘 | Maira BR Almudena SV Enrique GG | 2007 | American Journal of Clinical Nutrition2007，83，2： | 1 |
| 11 | The effects of two alleles of IGF2 on fat content in pig carcasses and pork显示文摘 | Carmen Burgos Almudena Galve Carlos Moreno Juan Altarriba Raquel Reina Carmen García Pascual López-Buesa | 2011 | Meat Science2011，，2： | 1 |
| 12 | Repair of acute myocardial infarction by human stemness factors induced pluripotent stem cells显示文摘 | NELSON T J PHD M D ALMUDENA MARTINEZ -FERNANDEZ | 2009 | Circulation2009，120，： | 1 |
| 13 | Repair of acute myocardial infarction by human sternness factors induced pluripotent stem cells显示文摘 | Timothy J Nelson Almudena Martinez -Femandez and | 2009 | Circulation2009，120，： | 1 |
| 14 | Olfactory ensheathing glia:properties and function显示文摘 | Almudena R C Jesfis A | 1998 | Brain Research Bulletin1998，46，3： | 1 |
| 15 | The influence of lactic bacteria on the quality of malt显示文摘 | DEIRDRE P ELKE K ALMUDENA M | 2005 | J Inst Brew2005，111，： | 1 |
| 16 | Environmental Evaluation of Different Treatment Processes for Sludge from Urban Wastewater Treatments: Anaerobic Digestion versus Thermal Processes 显示文摘 | Almudena Hospido Teresa Moreira Maria Martin | 2005 | Urban Wastewater Treatments2005，10，5： | 1 |
| 17 | Life cycle inventory of partiele- board: a case study in the woods sector显示文摘 | Beatriz R Almudena H Teresa M | 2006 | The International Journalof Life Cycle Assessment2006，11，2： | 1 |
| 18 | Atorvastatin Reduces the Expression of Prostaglandin E2 Receptors in Human Carotid Atherosclerotic Plaques and Monocytic Cells: Potential Implications for Plaque Stabilization显示文摘 | Almudena Gómez-Hernández Eva Sánchez-Galán José Luis Martín-Ventura Cristina Vidal Luis Miguel Blanco-Colio Mónica Ortego Melina Vega Javier Serrano Luis Ortega Gonzalo Hernández José Tunón Jesús Egido | 2006 | Journal of Cardiovascular Pharmacology2006，，1： | 1 |
| 19 | Application of lactic acid bacteria in malting and brewing显示文摘 | Helge M Ulmer Declan L Goode Almudena Soriano | 2004 | Brewers Digest2004，79，2： | 1 |
| 20 | Mechanism and kinetics of sulfamethoxazole photocatalytic ozonation in water 显示文摘 | Femando J B Almudena A Juan F G | 2009 | Water Research2009，43，5： | 1 |
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